专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08152462B1 Card seal with conical flexible seal 有权
标题翻译：卡密封带锥形柔性密封
公开(公告)号：US08152462B1
公开(公告)日：2012-04-10
申请号：US12543796
申请日：2009-08-19
申请人： Gregory C Williams
发明人： Gregory C Williams
IPC分类号： F01D11/02
CPC分类号： F01D11/02 , F05D2240/59 , F16J15/3292
摘要： A card seal with an annular arrangement of cards that are positioned within an annular groove of a casing, and a conical flexible seal is secured to the casing on the low pressure side of the cards. The cards and the flexible seal both includes slanted surfaces that interact during operation such that the flexible seal gap decreases with the rotor shaft and the cards are secured within the annular groove during assembly and installation of the card seal. The flexible seal blocks leakage through the cards and includes an axial extending inner end that can include an abradable material to allow for rub with the shaft while decreasing the gap to prevent leakage across the cards.
摘要翻译：具有定位在壳体的环形凹槽内的卡环的环形卡片和圆锥形柔性密封件的卡片密封件固定到卡片的低压侧上的壳体。卡片和柔性密封件都包括在操作期间相互作用的倾斜表面，使得柔性密封间隙随着转子轴的减小而减小，并且在组装和安装卡片密封件期间卡被固定在环形凹槽内。柔性密封件阻止通过卡片的泄漏，并且包括轴向延伸的内端，其可以包括可磨损材料，以允许与轴一起摩擦，同时减小间隙以防止渗漏在卡上。

2. 发明申请

US20110087004A1 ENHANCED ORAL TRANSCOMPARTMENTAL DELIVERY OF THERAPEUTIC OR DIAGNOSTIC AGENTS 审中-公开
标题翻译：治疗或诊断药物的加强口服转运
公开(公告)号：US20110087004A1
公开(公告)日：2011-04-14
申请号：US12818955
申请日：2010-06-18
申请人： Srinivasan Ramanathan , Stanley Stein , Michael Leibowitz , Patrick J. Sinko , Tamara Minko , Gregory C. Williams , Goubao Zhang , Xiaoping Zhang , Shahrair Pooyan , Seong Hee Park , Bo Qiu , Pankaj Paranjpe
发明人： Srinivasan Ramanathan , Stanley Stein , Michael Leibowitz , Patrick J. Sinko , Tamara Minko , Gregory C. Williams , Goubao Zhang , Xiaoping Zhang , Shahrair Pooyan , Seong Hee Park , Bo Qiu , Pankaj Paranjpe
IPC分类号： C07K7/06
CPC分类号： A61K38/08 , A61K47/60 , A61K47/62 , A61K47/665 , B82Y5/00
摘要： The invention is directed to pharmaceutical compositions and methods for delivery of a therapeutic or diagnostic agent from one bodily compartment to one or more other bodily compartment by administering one of the following conjugates: a polymer having multiple functional groups at least one of which is covalently bound to a therapeutic or diagnostic agent, and at least one cell uptake promoter covalently bound to the therapeutic or diagnostic agent; or a polymer and at least one cell uptake promoter bound thereto; the polymer further comprising multiple functional groups at least one of which is covalently bound a therapeutic or diagnostic agent.
摘要翻译：本发明涉及通过施用以下缀合物之一将治疗剂或诊断剂从一个身体隔室递送至一个或多个其它身体隔室的药物组合物和方法：具有多个官能团的聚合物，其中至少一个共价结合至少一种与治疗剂或诊断剂共价结合的细胞摄取促进剂; 或与其结合的聚合物和至少一种细胞摄取促进剂; 所述聚合物还包含多个官能团，其中至少一个与治疗剂或诊断剂共价结合。

3. 发明申请

US20130072447A1 ENHANCED ORAL TRANSCOMPARTMENTAL DELIVERY OF THERAPEUTIC OR DIAGANOSTIC AGENTS 审中-公开
标题翻译：治疗或诊断药物的加强口服转运
公开(公告)号：US20130072447A1
公开(公告)日：2013-03-21
申请号：US13471083
申请日：2012-05-14
申请人： Srinivasan Ramanathan , Stanley Stein , Michael Leibowitz , Patrick J. Sinko , Tamara Minko , Gregory C. Williams , Goubao Zhang , Xiaoping Zhang , Shahrair Pooyan , Seong Hee Park , Bo Qiu , Pankaj Paranjpe
发明人： Srinivasan Ramanathan , Stanley Stein , Michael Leibowitz , Patrick J. Sinko , Tamara Minko , Gregory C. Williams , Goubao Zhang , Xiaoping Zhang , Shahrair Pooyan , Seong Hee Park , Bo Qiu , Pankaj Paranjpe
IPC分类号： A61K47/48 , A61K38/08 , A61K47/34
CPC分类号： A61K38/08 , A61K47/60 , A61K47/62 , A61K47/665 , B82Y5/00
摘要： The invention is directed to pharmaceutical compositions and methods for delivery of a therapeutic or diagnostic agent from one bodily compartment to one or more other bodily compartment by administering one of the following conjugates: a polymer having multiple functional groups at least one of which is covalently bound to a therapeutic or diagnostic agent, and at least one cell uptake promoter covalently bound to the therapeutic or diagnostic agent; or a polymer and at least one cell uptake promoter bound thereto; the polymer further comprising multiple functional groups at least one of which is covalently bound a therapeutic or diagnostic agent.
摘要翻译：本发明涉及通过施用以下缀合物之一将治疗剂或诊断剂从一个身体隔室递送至一个或多个其它身体隔室的药物组合物和方法：具有多个官能团的聚合物，其中至少一个共价结合至少一种与治疗剂或诊断剂共价结合的细胞摄取促进剂; 或与其结合的聚合物和至少一种细胞摄取促进剂; 所述聚合物还包含多个官能团，其中至少一个与治疗剂或诊断剂共价结合。

4. 发明授权

US07740882B2 Enhanced oral and transcompartmental delivery of therapeutic or diagnostic agents 失效
标题翻译：增强口服和跨部门治疗或诊断药物的输送
公开(公告)号：US07740882B2
公开(公告)日：2010-06-22
申请号：US11170652
申请日：2005-06-29
申请人： Srinivasan Ramanathan , Stanley Stein , Michael Leibowitz , Patrick J. Sinko , Tamara Minko , Gregory C. Williams , Goubao Zhang , Xiaoping Zhang , Shahrair Pooyan , Seong Hee Park , Bo Qiu , Pankaj Paranjpe
发明人： Srinivasan Ramanathan , Stanley Stein , Michael Leibowitz , Patrick J. Sinko , Tamara Minko , Gregory C. Williams , Goubao Zhang , Xiaoping Zhang , Shahrair Pooyan , Seong Hee Park , Bo Qiu , Pankaj Paranjpe
IPC分类号： A61K9/20 , A61K38/04 , A61K38/00 , A61K51/00
CPC分类号： A61K47/48346 , A61K38/08 , A61K47/60 , A61K47/62 , A61K47/665 , B82Y5/00
摘要： The invention is directed to pharmaceutical compositions and methods for delivery of a therapeutic or diagnostic agent from one bodily compartment to one or more other bodily compartment by administering one of the following conjugates: a polymer having multiple functional groups at least one of which is covalently bound to a therapeutic or diagnostic agent, and at least one cell uptake promoter covalently bound to the therapeutic or diagnostic agent; or a polymer and at least one cell uptake promoter bound thereto; the polymer further comprising multiple functional groups at least one of which is covalently bound a therapeutic or diagnostic agent.
摘要翻译：本发明涉及通过施用以下缀合物之一将治疗剂或诊断剂从一个身体隔室递送至一个或多个其它身体隔室的药物组合物和方法：具有多个官能团的聚合物，其中至少一个共价结合至少一种与治疗剂或诊断剂共价结合的细胞摄取促进剂; 或与其结合的聚合物和至少一种细胞摄取促进剂; 所述聚合物还包含多个官能团，其中至少一个与治疗剂或诊断剂共价结合。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式