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1. 发明申请

US20100311865A1 Gypsum Board Containing Antimicrobial And Antibacterial Compounds 失效
标题翻译：含有抗菌和抗菌化合物的石膏板
公开(公告)号：US20100311865A1
公开(公告)日：2010-12-09
申请号：US12845979
申请日：2010-07-29
申请人： William Toreki , Gerald Olderman , Gregory Staab
发明人： William Toreki , Gerald Olderman , Gregory Staab
IPC分类号： C09D5/00
CPC分类号： A01N25/34 , A01N33/12 , B32B13/08 , E04C2/043 , Y10T428/31986 , Y10T428/31993 , Y10T428/31996 , A01N43/40 , A01N37/12 , A01N55/02 , A01N2300/00
摘要： A novel gypsum board having improved antimicrobial and antibacterial properties is disclosed. The board comprises a gypsum core, front and back paper facings, and a polymeric antimicrobial or antibacterial compound effective at inhibiting fungal growth. Preferred polymeric antimicrobial and antibacterial compounds include polyDADMAC, polyTMMC, and quaternized polyvinyl pyridine derivatives. The novel gypsum board further comprises a non-polymeric antimicrobial or antibacterial compound. Preferred non-polymeric antimicrobial or antibacteral compounds include cetyl pyridinium chloride and sodium pyrithione. The polymeric antimicrobial or antibacterial compound can be present in the gypsum core and/or on one or both of the paper facings. The non-polymeric antimicrobial or antibacterial compound may be encapsulated in a material or ionically associated with the polymeric antimicrobial or antibacterial compound to allow releases of the non-polymeric antimicrobial or antibacterial compound over time and/or upon exposure to moisture. Methods for preparing the aforementioned novel gypsum board are also disclosed.
摘要翻译：公开了具有改进的抗菌和抗菌性能的新型石膏板。该板包括石膏芯，正面和背面纸面，以及有效抑制真菌生长的聚合抗微生物或抗菌化合物。优选的聚合抗微生物和抗菌化合物包括polyDADMAC，polyTMMC和季铵化的聚乙烯吡啶衍生物。新型石膏板还包含非聚合抗微生物或抗菌化合物。优选的非聚合抗微生物或抗菌化合物包括氯化十六烷基吡啶鎓和吡啶硫酮钠。聚合物抗微生物或抗菌化合物可以存在于石膏芯中和/或在一个或两个纸面上。非聚合物抗微生物剂或抗菌化合物可以被包封在与聚合物抗微生物或抗菌化合物的离子缔合物质中，以允许随着时间和/或暴露于水分而释放非聚合物抗微生物剂或抗菌化合物。还公开了制备上述新型石膏板的方法。

2. 发明申请

US20100211035A1 Antimicrobial Bandage Material Comprising Superabsorbent and Non-Superabsorbent Layers 失效
标题翻译：包含超吸收剂和非超吸收层的抗菌绷带材料
公开(公告)号：US20100211035A1
公开(公告)日：2010-08-19
申请号：US12772686
申请日：2010-05-03
申请人： William Toreki , Gerald Olderman
发明人： William Toreki , Gerald Olderman
IPC分类号： A61L15/46
CPC分类号： A01N25/34 , A61F13/8405 , A61L15/46 , A61L2300/206 , A61L2300/208 , A61L2300/404 , A61L2300/606 , A01N25/10 , A01N33/12 , A01N47/44
摘要： This invention relates to methods and compositions for materials having a non-leaching coating that has antimicrobial properties. The coating is applied to substrates such as gauze-type wound dressings. Covalent, non-leaching, non-hydrolyzable bonds are formed between the substrate and the polymer molecules that form the coating. A high concentration of anti-microbial groups on multi-length polymer chains and relatively long average chain lengths, contribute to an absorbent or superabsorbent surface with a high level antimicrobial effect.
摘要翻译：本发明涉及具有抗菌性能的非浸出涂层的材料的方法和组合物。将涂层施加到诸如纱布式伤口敷料的基底上。在底物和形成涂层的聚合物分子之间形成共价，非浸出，不可水解的键。在多长度聚合物链上具有高浓度的抗微生物群和相当长的平均链长，有助于具有高水平抗微生物效果的吸收剂或超吸收剂表面。

3. 发明申请

US20080206293A1 Absorbent substrate with a non-leaching antimicrobial activity and a controlled-release bioactive agent. 审中-公开
标题翻译：具有非浸出抗菌活性的吸收性底物和受控释放的生物活性剂。
公开(公告)号：US20080206293A1
公开(公告)日：2008-08-28
申请号：US12036107
申请日：2008-02-22
申请人： William Toreki , Bernd Liesenfeld , David Moore , Gregory Schultz , Gerald Olderman , Gregory Staab
发明人： William Toreki , Bernd Liesenfeld , David Moore , Gregory Schultz , Gerald Olderman , Gregory Staab
IPC分类号： A61K9/00 , A61F13/00 , A61K31/65 , A61K38/18 , A01N25/08 , A01P1/00 , A61P31/04 , A61K38/02 , A01N25/00 , A61K31/165 , A61K31/14
CPC分类号： A61L15/44 , A61L15/46
摘要： This invention relates to antimicrobial wound dressings having a non-leaching antimicrobial activity, releasable antimicrobial and antiprotease agents, and a controlled-release bioactive agent such as doxycycline. The Wound dressing material is absorbent and acts as a substrate for antimicrobial and antiprotease agents as well as bioactive agents. More generally, this invention relates to methods and compositions for materials having a non-leaching coating that has antimicrobial properties. The coating is applied to substrates such as gauze-type wound dressings, powders and other substrates. Covalent, non-leaching, non-hydrolyzable bonds are formed between the substrate and the polymer molecules that form the coating. A high concentration of anti-microbial groups on multi-length polymeric molecules and relatively long average chain lengths, contribute to an absorbent or superabsorbent surface with a high level antimicrobial efficacy. Utilization of non-leaching coatings having a plurality of anionic or cationic sites is used according to this invention to bind a plurality of oppositely charged biologically or chemically active compounds, and to release the bound oppositely charged biologically or chemically active compounds from said substrate over a period of time to achieve desired objectives as diverse as improved wound healing to reduction in body odor.
摘要翻译：本发明涉及具有非浸出抗微生物活性的抗微生物伤口敷料，可释放的抗微生物剂和抗蛋白酶试剂，以及控释释放生物活性剂如多西环素。伤口敷料材料是吸收剂并用作抗微生物剂和抗蛋白酶剂以及生物活性剂的底物。更一般来说，本发明涉及具有抗菌性能的非浸出涂层的材料的方法和组合物。将涂层施加到诸如纱布式伤口敷料，粉末和其它底物的基底上。在底物和形成涂层的聚合物分子之间形成共价，非浸出，不可水解的键。在多长度聚合物分子上具有高浓度的抗微生物群和相当长的平均链长，有助于具有高水平抗微生物效能的吸收剂或超吸收剂表面。根据本发明使用具有多个阴离子或阳离子位点的非浸出涂层的使用以结合多个带相反电荷的生物或化学活性化合物，并通过一个或多个阴离子或化学活性化合物从所述底物上释放结合的带相反电荷的生物或化学活性化合物一段时间以达到预期的目标，如改善伤口愈合以减少体臭。

4. 发明授权

US08343523B2 Disinfectant with durable activity based on alcohol-soluble quaternary ammonium polymers and copolymers 失效
标题翻译：基于醇溶性季铵聚合物和共聚物的具有持久活性的消毒剂
公开(公告)号：US08343523B2
公开(公告)日：2013-01-01
申请号：US12350784
申请日：2009-01-08
申请人： William Toreki , Gerald Olderman , Rustom S. Kanga
发明人： William Toreki , Gerald Olderman , Rustom S. Kanga
IPC分类号： A01N33/02 , A01N25/00 , A01P1/00
CPC分类号： A01N47/44 , A01N33/12 , A01N31/02 , A01N31/16 , A01N2300/00
摘要： An alcohol- or glycol-soluble, water-insoluble, disinfectant composition and a method of using the same for disinfecting and for providing a prolonged antimicrobial property to a variety of surfaces, including skin. The composition comprises at least one alcohol or glycol and an antimicrobial polymer that is capable of imparting an antimicrobial property to a surface without the use of a metal or a metal-containing compound. The composition is applied to a surface and allowed to evaporate leaving a coating of antimicrobial polymer. Alternatively, the composition is incorporated into or within the substrate.
摘要翻译：醇或二醇可溶的水不溶性消毒剂组合物及其使用方法，用于消毒，并为多种表面（包括皮肤）提供延长的抗微生物性能。组合物包含至少一种醇或二醇和能够赋予表面抗微生物性能而不使用金属或含金属的化合物的抗微生物聚合物。将组合物施加到表面并允许蒸发，留下抗微生物聚合物的涂层。或者，将组合物掺入或在基底内。

5. 发明申请

US20060194072A1 Antifungal gypsum board 失效
公开(公告)号：US20060194072A1
公开(公告)日：2006-08-31
申请号：US10546850
申请日：2004-02-25
申请人： William Toreki , Gerald Olderman , Gregory Staab
发明人： William Toreki , Gerald Olderman , Gregory Staab
IPC分类号： B32B13/08 , B05D3/02 , B05D1/02
CPC分类号： A01N25/34 , A01N33/12 , B32B13/08 , E04C2/043 , Y10T428/31986 , Y10T428/31993 , Y10T428/31996 , A01N43/40 , A01N37/12 , A01N55/02 , A01N2300/00
摘要： A novel improved gypsum board having improved antifungal properties is disclosed. The board comprises a gypsum core, front and back paper facings and a polymeric antifungal agent effective at inhibiting fungal growth. A preferred polymeric antifungal agent is polyDADMAC or polyTMMC. In addition to the polymeric antifungal agent, a non-polymeric antifungal agent, such as cetyl pyridinium chloride, sodium or zinc pyrithione, or both, may be included. The polymeric antifungal agent can be present in the gypsum core and/or on one or both of the paper facings. In addition, the antifungal agent may be encapsulated in a material or ionically associated with the polymeric antifungal agent, that releases the antifungal agent over time and/or upon exposure to moisture. Also disclosed are methods for preparing the aforementioned improved antifungal gypsum board.

6. 发明申请

US20090246165A1 Disinfectant with Quarternary Ammonium Polymer and Copolymers 有权
标题翻译：具有季铵聚合物和共聚物的消毒剂
公开(公告)号：US20090246165A1
公开(公告)日：2009-10-01
申请号：US12064487
申请日：2006-08-22
申请人： William Toreki , Gerald Olderman
发明人： William Toreki , Gerald Olderman
IPC分类号： A61K31/74 , A01N33/12 , A61P31/00 , A01P1/00
CPC分类号： A01N33/12 , A01N25/02 , A01N25/10 , A01N31/02 , A01N47/44 , A01N2300/00
摘要： An alcohol-soluble, water-insoluble, disinfectant composition and a method of using the same for disinfecting and for providing a prolonged antimicrobial property to a variety of surfaces, including skin. The composition comprises an antimicrobial polymer that is capable of imparting an antimicrobial property to a surface without the use of a metal or metal-containing compound. The composition is applied to a surface and allowed to evaporate leaving a coating of antimicrobial polymer.
摘要翻译：醇溶性，水不溶性消毒剂组合物以及使用该组合物进行消毒并为各种表面（包括皮肤）提供延长的抗微生物性能的方法。该组合物包含抗微生物聚合物，其能够在不使用含金属或金属的化合物的情况下赋予表面抗微生物性能。将组合物施加到表面并允许蒸发，留下抗微生物聚合物的涂层。

7. 发明申请

US20090117164A1 Disinfectant with Durable Activity Based on Alcohol-Soluble Quaternary Ammonium Polymers and Copolymers 失效
标题翻译：基于醇溶性季铵盐聚合物和共聚物的耐久活性消毒剂
公开(公告)号：US20090117164A1
公开(公告)日：2009-05-07
申请号：US12350784
申请日：2009-01-08
申请人： William Toreki , Gerald Olderman
发明人： William Toreki , Gerald Olderman
IPC分类号： A01N33/02 , A01P1/00 , A01N25/00
CPC分类号： A01N47/44 , A01N33/12 , A01N31/02 , A01N31/16 , A01N2300/00
摘要： An alcohol- or glycol-soluble, water-insoluble, disinfectant composition and a method of using the same for disinfecting and for providing a prolonged antimicrobial property to a variety of surfaces, including skin. The composition comprises at least one alcohol or glycol and an antimicrobial polymer that is capable of imparting an antimicrobial property to a surface without the use of a metal or a metal-containing compound. The composition is applied to a surface and allowed to evaporate leaving a coating of antimicrobial polymer. Alternatively, the composition is incorporated into or within the substrate.
摘要翻译：醇或二醇可溶的水不溶性消毒剂组合物及其使用方法，用于消毒，并为多种表面（包括皮肤）提供延长的抗微生物性能。组合物包含至少一种醇或二醇和能够赋予表面抗微生物性能而不使用金属或含金属的化合物的抗微生物聚合物。将组合物施加到表面并允许蒸发，留下抗微生物聚合物的涂层。或者，将组合物掺入或在基底内。

8. 发明申请

US20050033251A1 Controlled release of biologically active substances from select substrates 审中-公开
标题翻译：从选择的底物控制释放生物活性物质
公开(公告)号：US20050033251A1
公开(公告)日：2005-02-10
申请号：US10786959
申请日：2004-02-25
申请人： William Toreki , Gregory Staab , Gerald Olderman
发明人： William Toreki , Gregory Staab , Gerald Olderman
IPC分类号： A61F13/15 , A61L15/46 , A61F13/20
CPC分类号： A61L15/46 , A01N25/34 , A61F13/8405 , A61L2300/206 , A61L2300/208 , A61L2300/404 , A61L2300/606 , A01N25/10 , A01N33/12 , A01N47/44
摘要： This invention relates to methods and compositions for materials having a non-leaching coating that has antimicrobial properties. The coating is applied to substrates such as gauze-type wound dressings, powders and other substrates. Covalent, non-leaching, non-hydrolyzable bonds are formed between the substrate and the polymer molecules that form the coating. A high concentration of anti-microbial groups on multi-length polymer chains and relatively long average chain lengths, contribute to an absorbent or superabsorbent surface with a high level antimicrobial efficacy. Utilization of non-leaching coatings having a plurality of anionic or cationic sites is used according to this invention to bind a plurality of oppositely charged biologically or chemically active compounds, and to release the bound oppositely charged biologically or chemically active compounds from said substrate over a period of time to achieve desired objectives as diverse as improved wound healing to reduction in body odor.
摘要翻译：本发明涉及具有抗菌性能的非浸出涂层的材料的方法和组合物。将涂层施加到诸如纱布式伤口敷料，粉末和其它底物的基底上。在底物和形成涂层的聚合物分子之间形成共价，非浸出，不可水解的键。在多长度聚合物链上具有高浓度的抗微生物群和相当长的平均链长，有助于具有高水平抗微生物效能的吸收剂或超吸收剂表面。根据本发明使用具有多个阴离子或阳离子位点的非浸出涂层的使用以结合多个带相反电荷的生物或化学活性化合物，并通过一个或多个化学活性化合物从所述底物上释放结合的带相反电荷的生物或化学活性化合物一段时间以达到预期的目标，如改善伤口愈合以减少体臭。

9. 发明授权

US08227017B2 System and method for enhancing the efficacy of antimicrobial contact lenses and other surfaces 失效
标题翻译：用于增强抗微生物隐形眼镜和其它表面的功效的系统和方法
公开(公告)号：US08227017B2
公开(公告)日：2012-07-24
申请号：US12742923
申请日：2008-11-13
申请人： Susan Leander , William Toreki , Gerald Olderman , Albina Mikhaylova
发明人： Susan Leander , William Toreki , Gerald Olderman , Albina Mikhaylova
IPC分类号： B05D3/10 , A61K9/08 , G02C7/04
CPC分类号： A61L12/08 , A61L12/145
摘要： A system and method of enhancing the antimicrobial and biofilm-resistant efficacy of surfaces that have cationic polyelectrolytes nonleachably bound thereto in order to impart antimicrobial activity to the surface. The system for enhancing antimicrobial efficacy involves brushing, dipping, wiping, spraying, or storing the surface in a solution containing citrate ion. The method involves treatment of the surface with a solution which enhances the antimicrobial and biofilm-resistant efficacy of the surface, and which prevents a loss of the antimicrobial properties of the surface which may occur over time. Preferably, the enhancement agent is citrate ion and the cationic polyelectrolyte is poly(diallyldimethylammonium chloride), also known as polyDADMAC. The system is particularly beneficial for surfaces of articles such as contact lenses.
摘要翻译：提高具有阳离子聚电解质与其无关的表面的抗微生物和抗生物膜抗性功效的系统和方法，以赋予表面抗微生物活性。用于增强抗微生物功效的系统涉及刷洗，浸渍，擦拭，喷雾或将表面储存在含有柠檬酸根离子的溶液中。该方法包括用提高表面的抗微生物和抗生物膜的功效的溶液处理表面，并且防止表面随时间发生的抗微生物性能的损失。优选地，增强剂是柠檬酸根离子，阳离子聚电解质是聚（二烯丙基二甲基氯化铵），也称为聚DADMAC。该系统特别有益于诸如隐形眼镜的物品的表面。

10. 发明申请

US20120141396A1 SKIN DISINFECTANT WITH QUATERNARY AMMONIUM POLYMERS 审中-公开
标题翻译：皮肤与季铵盐聚合物的消毒剂
公开(公告)号：US20120141396A1
公开(公告)日：2012-06-07
申请号：US13341470
申请日：2011-12-30
申请人： William Toreki , Gerald Olderman
发明人： William Toreki , Gerald Olderman
IPC分类号： A61K31/785 , A61P39/00 , A61P31/00
CPC分类号： A01N33/12 , A01N25/02 , A01N25/10 , A01N31/02 , A01N47/44 , A01N2300/00
摘要： An alcohol-soluble, water-insoluble, disinfectant composition and a method of using the same for disinfecting and for providing a prolonged antimicrobial property to a variety of surfaces, including skin. The composition comprises an antimicrobial polymer that is capable of imparting an antimicrobial property to a surface without the use of a metal or metal-containing compound. The composition is applied to a surface and allowed to evaporate leaving a coating of antimicrobial polymer.
摘要翻译：醇溶性，水不溶性消毒剂组合物以及使用该组合物进行消毒并为各种表面（包括皮肤）提供延长的抗微生物性能的方法。该组合物包含抗微生物聚合物，其能够在不使用含金属或金属的化合物的情况下赋予表面抗微生物性能。将组合物施加到表面并允许蒸发，留下抗微生物聚合物的涂层。

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