专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20120015899A1 MODIFIED PLANT VIRUS PARTICLES AND USES THEREFOR 审中-公开
标题翻译：改良植物病毒颗粒及其用途
公开(公告)号：US20120015899A1
公开(公告)日：2012-01-19
申请号：US13125482
申请日：2009-10-25
申请人： George Lomonossoff , David Evans , Elisabet de los Pinos , Frank Sainsbury
发明人： George Lomonossoff , David Evans , Elisabet de los Pinos , Frank Sainsbury
IPC分类号： A61K31/7068 , C12N1/19 , C12N1/21 , A61P35/00 , C12N5/07
CPC分类号： C07K14/005 , A61K48/00 , C07K2319/85 , C12N7/00 , C12N2770/14023 , C12N2770/14042 , C12N2770/14045 , C12N2795/18123 , C12N2810/00 , C12N2810/10 , C12N2810/405
摘要： Aspects of the invention provide modified virus-like particles that are designed for therapeutic applications. In particular, aspects of the invention provide CCMV coat proteins that are modified to generate virus-like particles, including mosaic virus-like particles, that can package and/or deliver one or more diagnostic and/or therapeutic agents. The invention also provides methods for treating subjects with one or more modified virus-like particles.
摘要翻译：本发明的方面提供被设计用于治疗应用的经修饰的病毒样颗粒。特别地，本发明的方面提供了经修饰以产生病毒样颗粒（包括花叶病毒样颗粒）的CCMV外壳蛋白，其可包装和/或递送一种或多种诊断和/或治疗剂。本发明还提供了用一种或多种经修饰的病毒样颗粒治疗受试者的方法。

2. 发明授权

US08519113B2 Bipartite system, method and composition for the constitutive and inducible expression of high levels of foreign proteins in plants 有权
标题翻译：用于植物中高水平外源蛋白的组成型和诱导型表达的二分体系，方法和组成
公开(公告)号：US08519113B2
公开(公告)日：2013-08-27
申请号：US12300922
申请日：2006-05-22
申请人： George Lomonossoff , Li Liu , Carmen Canizares , Marc-Andre D'Aoust , Louis-Philippe Vezina
发明人： George Lomonossoff , Li Liu , Carmen Canizares , Marc-Andre D'Aoust , Louis-Philippe Vezina
IPC分类号： C12N15/83 , C12N15/40 , C12N7/01 , C12N5/14 , A01H5/00
CPC分类号： C12N15/8203 , C12N15/8218 , C12N15/8257 , C12N15/8258
摘要： This invention comprises a combined transgene/virus vector system for the expression of heterologous proteins in plants. While exemplified with respect to the bipartite RNA plant virus, Cowpect mosaic virus (CPMV), other bipartite viral systems may be used to advantage according to the method, system and composition described in detail herein.
摘要翻译：本发明包括用于在植物中表达异源蛋白质的组合的转基因/病毒载体系统。尽管关于两部分RNA植物病毒的例证，根据本文详细描述的方法，系统和组合，可以使用考威花叶病毒（CPMV），其他二分之一病毒系统。

3. 发明授权

US06649813B2 Induction of resistance to virus diseases by transformation of plants with a plant virus replicase gene 失效
标题翻译：通过用植物病毒复制酶基因转化植物来诱导对病毒疾病的抗性
公开(公告)号：US06649813B2
公开(公告)日：2003-11-18
申请号：US08708354
申请日：1996-09-04
申请人： Milton Zaitlin , Daniel Golemboski , George Lomonossoff
发明人： Milton Zaitlin , Daniel Golemboski , George Lomonossoff
IPC分类号： C12N1582
CPC分类号： C12N9/127 , C07K14/005 , C12N15/8283 , C12N2770/00022
摘要： The invention described herein discloses a virus-induced resistance that may be transferred from one plant generation to another in which transgenic plants containing a coding sequence, taken from the read-through portion of the replicase portion of the viral genome, are resistant to subsequent disease by the virus. The use of the 54 kDa coding sequence from TMV is described as a specific example of the broader technology. Thus, the invention defines a means for bringing about viral resistance in plants which have been transformed with nucleic acid copies of fragments or segments taken from the replicase portion of the pathogenic virus genome. In addition, the present invention defines transformed plants and their seeds which carry a portion of the viral genome which encodes for a portion of the read-through portion of the replicase genome of the pathogenic virus.
摘要翻译：本文所述的本发明公开了可以从一个植物代转移到另一个植物的病毒诱导的抗性，其中含有编码序列的转基因植物取自病毒基因组的复制酶部分的直读部分对后续疾病具有抗性由病毒。将来自TMV的54kDa编码序列的使用描述为更广泛技术的具体实例。因此，本发明限定了在已经用片段或片段的核酸拷贝从病原病毒基因组的复制酶部分取代的植物中产生病毒抗性的手段。此外，本发明定义了转化的植物及其种子，其携带病毒基因组的一部分，其编码病原体病毒的复制子基因组的部分透读部分。

4. 发明申请

US20160122420A1 ANTIBODY DISPLAY 审中-公开
标题翻译：抗体显示
公开(公告)号：US20160122420A1
公开(公告)日：2016-05-05
申请号：US14896343
申请日：2014-06-05
申请人： David J. ROWLANDS , George LOMONOSSOFF , Hadrien PEYRET
发明人： David J. ROWLANDS , George LOMONOSSOFF , Hadrien PEYRET
IPC分类号： C07K16/18 , C12N7/00 , G01N33/68 , C07K14/005
CPC分类号： C07K16/18 , C07K14/005 , C07K14/02 , C07K16/00 , C07K2317/22 , C07K2317/569 , C07K2319/35 , C07K2319/735 , C07K2319/75 , C12N7/00 , C12N2730/10122 , C12N2730/10123 , C12N2730/10134 , C12N2730/10142 , C12N2730/10151 , G01N33/6857 , G01N2333/02
摘要： The invention provides a protein comprising a first and a second copy of hepatitis B core antigen (HBcAg) in tandem, in which one or both of the copies of HBcAg comprises a single-domain antibody fragment in the el loop.
摘要翻译：本发明提供一种包含乙型肝炎核心抗原（HBcAg）的第一和第二拷贝的蛋白质，其中HBcAg的一个或两个拷贝在el环中包含单结构域抗体片段。

5. 发明申请

US20090181460A1 Bipartite System, Method and Composition for the Constitutive and Inducible Expression of High Levels of Foreign Proteins in Plants 有权
标题翻译：用于植物中高水平外源蛋白的组成型和诱导表达的双系统，方法和组成
公开(公告)号：US20090181460A1
公开(公告)日：2009-07-16
申请号：US12300922
申请日：2006-05-22
申请人： George Lomonossoff , Li Liu , Carmen Canizares , Marc-Andre D'Aoust , Louis-Philippe Vezina
发明人： George Lomonossoff , Li Liu , Carmen Canizares , Marc-Andre D'Aoust , Louis-Philippe Vezina
IPC分类号： C12N15/82 , C12N15/63 , A01H5/00 , C12N5/04
CPC分类号： C12N15/8203 , C12N15/8218 , C12N15/8257 , C12N15/8258
摘要： This invention comprises a combined transgene/virus vector system for the expression of heterologous proteins in plants. While exemplified with respect to the bipartite RNA plant virus, Cowpect mosaic virus (CPMV), other bipartite viral systems may be used to advantage according to the method, system and composition described in detail herein.
摘要翻译：本发明包括用于在植物中表达异源蛋白质的组合的转基因/病毒载体系统。尽管关于两部分RNA植物病毒的例证，根据本文详细描述的方法，系统和组合，可以使用考威花叶病毒（CPMV），其他二分之一病毒系统。

6. 发明授权

US5596132A Induction of resistance to virus diseases by transformation of plants with a portion of a plant virus genome involving a read-through replicase gene 失效
标题翻译：通过植物病毒基因组转化植物来感染病毒性疾病，涉及到一种可读复制基因
公开(公告)号：US5596132A
公开(公告)日：1997-01-21
申请号：US488672
申请日：1995-06-07
申请人： Milton Zaitlin , Daniel Golemboski , George Lomonossoff
发明人： Milton Zaitlin , Daniel Golemboski , George Lomonossoff
IPC分类号： C07K14/08 , C12N9/12 , C12N15/33 , C12N15/82 , A01H4/00 , C12N5/14 , C12N15/40
CPC分类号： C12N9/127 , C07K14/005 , C12N15/8283 , C12N2770/00022
摘要： The invention described herein discloses a virus-induced resistance that may be transferred from one plant generation to another in which transgenic plants containing a coding sequence, taken from the read-through portion of the replicase portion of the viral genome, are resistant to subsequent disease by the virus. The use of the 54 kDa coding sequence from TMV is described as a specific example of the broader technology. Thus, the invention defines a means for bringing about viral resistance in plants which have been transformed with nucleic acid copies of fragments or segments taken from the replicase portion of the pathogenic virus genome. In addition, the present invention defines transformed plants and their seeds which carry a portion of the viral genome which codes for a portion of the read-through portion of the replicase genome of the pathogenic virus.
摘要翻译：本文所述的本发明公开了可以从一个植物代转移到另一个植物的病毒诱导的抗性，其中含有编码序列的转基因植物取自病毒基因组的复制酶部分的直读部分对后续疾病具有抗性由病毒。将来自TMV的54kDa编码序列的使用描述为更广泛技术的具体实例。因此，本发明限定了在已经用片段或片段的核酸拷贝从病原病毒基因组的复制酶部分取代的植物中产生病毒抗性的手段。此外，本发明定义了转化的植物及其种子，其携带病毒基因组的一部分，其编码致病病毒的复制酶基因组的部分透读部分。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式