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1. 发明公开

EP1274358A1 GENERATING SCANNING SPOT LOCATIONS FOR LASER EYE SURGERY 有权
标题翻译：正式扫描目标点眼激光手术
公开(公告)号：EP1274358A1
公开(公告)日：2003-01-15
申请号：EP01920403.1
申请日：2001-03-14
申请人： Visx, Incorporated , Yee, Kingman , Gross, Erik
发明人： YEE, Kingman , GROSS, Erik
IPC分类号： A61B18/18
CPC分类号： A61F9/008 , A61F9/00804 , A61F2009/00844 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882 , A61F2009/00897
摘要： Scanning spot locations are generated for ablating tissue using a scanning laser beam (104) over a treatment region by fitting a target function representing a desired lens profile of scanning spots in a particular treatment pattern. Symmetry effects are utilized to simplify the process for determining the scanning spot locations. In some embodiments, the basis function is a two-dimensional function representing a two-dimensional section of a three-dimensional treatment profile which has symmetry a with respect to the two-dimensional section extending along the treatment pattern. For example, the treatment pattern is generally straight for myopic and hyperopic cylinders, and is generally circular for myopia and hyperopia. The target function and the basis function may be discrete for implementation in a software algorithm (20), and be fitted using a least square fit. The fit produces ablation depths for discrete scanning spots which are used to calculate the number of pulses at each reference position along the two-dimensional section. The pulses are distributed along the treatment pattern to produce the desired overlapping effect.

2. 发明申请

WO2007106657A3 SPATIAL FREQUENCY WAVEFRONT SENSOR SYSTEM AND METHOD 审中-公开
标题翻译：空间波形传感器系统及方法
公开(公告)号：WO2007106657A3
公开(公告)日：2008-10-23
申请号：PCT/US2007062809
申请日：2007-02-26
申请人： AMO MFG USA LLC , GROSS ERIK , CAMPBELL CHARLES
发明人： GROSS ERIK , CAMPBELL CHARLES
IPC分类号： G01J1/20 , G01B11/02 , G06K9/36
CPC分类号： G01M11/0264 , A61B3/1015
摘要： Devices systems, and methods can characterize an optical surface of an object. A wavefront sensor system focuses light energy propagating from the object to form a pattern on a detector. The system maps the pattern to an array with a transform function such as a Fourier transform. The values of array correspond to characteristic locations and signals in a transform space, for example an intensity of spatial frequency signals in frequency space. The characteristic location and intensity of these signals in transform space are used to measure the optical surface. For example, a characteristic frequency of a spatial frequency intensity peak in Fourier transform space can be used to estimate the location of spots on the detector. Alternatively, the characteristics can be used to the measure sphere, cylinder and axis of a wavefront, wavefront elevation maps and point spread functions, often without locating positions of individual spots on the detector.
摘要翻译：设备系统和方法可以表征物体的光学表面。波前传感器系统聚焦从物体传播的光能以在检测器上形成图案。系统将模式映射到具有诸如傅里叶变换的变换函数的数组。阵列的值对应于变换空间中的特征位置和信号，例如频率空间中的空间频率信号的强度。这些信号在变换空间中的特征位置和强度用于测量光学表面。例如，可以使用傅里叶变换空间中的空间频率强度峰值的特征频率来估计检测器上的斑点的位置。或者，特征可以用于波前的测量球体，圆柱体和轴线，波前高程图和点扩散函数，通常不定位检测器上各个点的位置。

3. 发明申请

WO03077795A9 BLEND AND TRANSITION ZONES FOR CORNEAL ABLATIONS 审中-公开
标题翻译：混合和过渡区域进行退火
公开(公告)号：WO03077795A9
公开(公告)日：2004-02-19
申请号：PCT/US0307903
申请日：2003-03-12
申请人： VISX INC , GROSS ERIK , HOFER RICH , WONG JONATHAN
发明人： GROSS ERIK , HOFER RICH , WONG JONATHAN
IPC分类号： A61F20060101 , A61F9/007 , A61F9/01
CPC分类号： A61F9/008 , A61F9/00806 , A61F9/00808 , A61F9/00817 , A61F2009/00844 , A61F2009/00846 , A61F2009/00848 , A61F2009/00872 , A61F2009/0088
摘要： Methods, devices, and systems for reprofiling a surface of a cornea (104) of an eye ablate a portion of the cornea to create an ablation zone (103) with an optically correct central optical zone (110) disposed in a central portion of the cornea, and a blend zone disposed peripherally to the central optical zone and at least partially within an optical zone (108) of the eye. The blend zone can have an optical power that gradually diminishes with increasing radius from the central optical zone.
摘要翻译：用于重新生成眼睛角膜（104）的表面的方法，装置和系统消融角膜的一部分以产生具有光学校正的中心光学区（110）的消融区（103），所述光学校正中心光学区设置在角膜，以及配置区域，其设置在所述中心光学区域周围并且至少部分地位于所述眼睛的光学区域（108）内。混合区域可以具有随中心光学区域的半径增加而逐渐减小的光学功率。

4. 发明申请

WO2005081955A3 VOLUMETRIC POINT SPREAD FUNCTION FOR EYE DIAGNOSIS AND TREATMENT 审中-公开
标题翻译：用于眼睛诊断和治疗的体积点扩展功能
公开(公告)号：WO2005081955A3
公开(公告)日：2007-06-07
申请号：PCT/US2005005708
申请日：2005-02-22
申请人： VISX INC , GROSS ERIK , DAI GUANGMING , CAMPBELL CHARLES
发明人： GROSS ERIK , DAI GUANGMING , CAMPBELL CHARLES
IPC分类号： A61B3/10 , A61B3/02 , A61B3/103
CPC分类号： A61B3/0025 , A61F2009/00872
摘要： Systems and methods analyze, diagnose, and/or treat a patient's eye using modified forms of the point spread function ("PSF") tailored to the vision system. Factors that alter perception of visual aberrations can be included and/or volumetric point spread functions calculated, often using point spread function calculations throughout a range of optical distances to more fully indicate the variation in visual perception of optics at different distances. A variety of visual affects of the human optical system can be simulated, analyzed, and modeled, including: single versus multiple wavelength sources, chromatic aberrations, retinal resolution, wavelength-dependent visual response, Stiles-Crawford effects, and/or non-linearity of retinal response. The perceived point spread function can offer objective confirmation of the patient's visual perception, allow a treating physician to see a closer approximation of what the patient sees, indicate the scale and significance of wavefront aberrations, and/or show which aberrations affect vision and which do not.
摘要翻译：系统和方法使用针对视觉系统定制的点扩散功能（“PSF”）的修改形式来分析，诊断和/或治疗患者的眼睛。可以包括改变视觉异常感知的因素和/或体积点扩散函数，通常在光学距离范围内使用点扩散函数计算，以更完全地指示不同距离的光学器件的视觉感知的变化。可以模拟，分析和建模人类光学系统的各种视觉影响，包括：单波长与多波长源，色差，视网膜分辨率，波长依赖视觉反应，Stiles-Crawford效应和/或非线性的视网膜反应。感知点扩散功能可以提供患者视觉感知的客观确认，允许治疗医师看到患者看到的更接近的近似值，指示波前像差的规模和意义，和/或显示哪些像差影响视力，哪些不。

5. 发明申请

WO2003077795A2 APPLICATION OF BLEND ZONES, DEPTH REDUCTION, AND TRANSITION ZONES TO ABLATION SHAPES 审中-公开
标题翻译：混合区，深度减少和过渡区应用于排列形状
公开(公告)号：WO2003077795A2
公开(公告)日：2003-09-25
申请号：PCT/US2003/007903
申请日：2003-03-12
申请人： VISX, INC. , GROSS, Erik , HOFER, Rich , WONG, Jonathan
发明人： GROSS, Erik , HOFER, Rich , WONG, Jonathan
IPC分类号： A61F
CPC分类号： A61F9/008 , A61F9/00806 , A61F9/00808 , A61F9/00817 , A61F2009/00844 , A61F2009/00846 , A61F2009/00848 , A61F2009/00872 , A61F2009/0088
摘要： Methods, devices, and systems for reprofiling a surface of a cornea of an eye ablate a portion of the cornea to create an ablation zone with an optically correct central optical zone disposed in a central portion of the cornea, and a blend zone disposed peripherally to the central optical zone and at least partially within an optical zone of the eye. The blend zone can have an optical power that gradually diminishes with increasing radius from the central optical zone.
摘要翻译：用于重新生成眼睛角膜表面的方法，装置和系统消融角膜的一部分以产生具有设置在角膜中心部分的光学校正中心光学区的消融区，以及混合区，中心光学区域并且至少部分地在眼睛的光学区域内。混合区域可以具有随中心光学区域的半径增加而逐渐减小的光学功率。

6. 发明申请

WO2007106657A2 SPATIAL FREQUENCY WAVEFRONT SENSOR SYSTEM AND METHOD 审中-公开
标题翻译：空间频率波形传感器系统及方法
公开(公告)号：WO2007106657A2
公开(公告)日：2007-09-20
申请号：PCT/US2007062809
申请日：2007-02-26
申请人： VISX INC , GROSS ERIK , CAMPBELL CHARLES
发明人： GROSS ERIK , CAMPBELL CHARLES
CPC分类号： G01M11/0264 , A61B3/1015
摘要： Devices systems, and methods can characterize an optical surface of an object. A wavefront sensor system focuses light energy propagating from the object to form a pattern on a detector. The system maps the pattern to an array with a transform function such as a Fourier transform. The values of array correspond to characteristic locations and signals in a transform space, for example an intensity of spatial frequency signals in frequency space. The characteristic location and intensity of these signals in transform space are used to measure the optical surface. For example, a characteristic frequency of a spatial frequency intensity peak in Fourier transform space can be used to estimate the location of spots on the detector. Alternatively, the characteristics can be used to the measure sphere, cylinder and axis of a wavefront, wavefront elevation maps and point spread functions, often without locating positions of individual spots on the detector.
摘要翻译：设备系统和方法可以表征物体的光学表面。波前传感器系统聚焦从物体传播的光能以在检测器上形成图案。系统将模式映射到具有诸如傅里叶变换的变换函数的数组。阵列的值对应于变换空间中的特征位置和信号，例如频率空间中的空间频率信号的强度。这些信号在变换空间中的特征位置和强度用于测量光学表面。例如，可以使用傅里叶变换空间中的空间频率强度峰值的特征频率来估计检测器上的斑点的位置。或者，该特征可以用于测量球体，波前的圆柱体和轴线，波前高程图和点扩散函数，通常不会在检测器上定位各个点的位置。

7. 发明申请

WO2005081955A2 VOLUMETRIC POINT SPREAD FUNCTION FOR EYE DIAGNOSIS AND TREATMENT 审中-公开
标题翻译：用于眼睛诊断和治疗的体积点扩展功能
公开(公告)号：WO2005081955A2
公开(公告)日：2005-09-09
申请号：PCT/US2005/005708
申请日：2005-02-22
申请人： VISX, INCORPORATED , GROSS, Erik , DAI, Guangming , CAMPBELL, Charles
发明人： GROSS, Erik , DAI, Guangming , CAMPBELL, Charles
IPC分类号： A61B3/02 , A61B3/103
CPC分类号： A61B3/0025 , A61F2009/00872
摘要： Systems and methods analyze, diagnose, and/or treat a patient's eye using modified forms of the point spread function ("PSF") tailored to the vision system. Factors that alter perception of visual aberrations can be included and/or volumetric point spread functions calculated, often using point spread function calculations throughout a range of optical distances to more fully indicate the variation in visual perception of optics at different distances. A variety of visual affects of the human optical system can be simulated, analyzed, and modeled, including: single versus multiple wavelength sources, chromatic aberrations, retinal resolution, wavelength-dependent visual response, Stiles-Crawford effects, and/or non-linearity of retinal response. The perceived point spread function can offer objective confirmation of the patient's visual perception, allow a treating physician to see a closer approximation of what the patient sees, indicate the scale and significance of wavefront aberrations, and/or show which aberrations affect vision and which do not.
摘要翻译：系统和方法使用针对视觉系统定制的点扩散功能（“PSF”）的修改形式来分析，诊断和/或治疗患者的眼睛。可以包括改变视觉异常感知的因素和/或体积点扩散函数，通常在光学距离范围内使用点扩散函数计算，以更完全地指示不同距离的光学器件的视觉感知的变化。可以模拟，分析和建模人类光学系统的各种视觉影响，包括：单波长与多波长源，色差，视网膜分辨率，波长依赖视觉反应，Stiles-Crawford效应和/或非线性的视网膜反应。感知点扩散功能可以提供患者视觉感知的客观确认，允许治疗医师看到患者看到的更接近的近似值，指示波前像差的规模和意义，和/或显示哪些像差影响视力，哪些不。

8. 发明申请

WO2007106657A9 SPATIAL FREQUENCY WAVEFRONT SENSOR SYSTEM AND METHOD 审中-公开
公开(公告)号：WO2007106657A9
公开(公告)日：2007-09-20
申请号：PCT/US2007/062809
申请日：2007-02-26
申请人： AMO MANUFACTURING USA, LLC , GROSS, Erik , CAMPBELL, Charles
发明人： GROSS, Erik , CAMPBELL, Charles
IPC分类号： G01M11/02 , A61B3/10
摘要： Devices systems, and methods can characterize an optical surface of an object. A wavefront sensor system focuses light energy propagating from the object to form a pattern on a detector. The system maps the pattern to an array with a transform function such as a Fourier transform. The values of array correspond to characteristic locations and signals in a transform space, for example an intensity of spatial frequency signals in frequency space. The characteristic location and intensity of these signals in transform space are used to measure the optical surface. For example, a characteristic frequency of a spatial frequency intensity peak in Fourier transform space can be used to estimate the location of spots on the detector. Alternatively, the characteristics can be used to the measure sphere, cylinder and axis of a wavefront, wavefront elevation maps and point spread functions, often without locating positions of individual spots on the detector.

9. 发明申请

WO2004112588A3 ITERATIVE FOURIER RECONSTRUCTION FOR LASER SURGERY AND OTHER OPTICAL APPLICATIONS 审中-公开
公开(公告)号：WO2004112588A3
公开(公告)日：2004-12-29
申请号：PCT/US2004/020733
申请日：2004-06-17
申请人： VISX, INCORPORATED , CHERNYAK, Dimitri , CAMPBELL, Charles, E. , GROSS, Erik , SOMANI, Seema , DAI, Guangming
发明人： CHERNYAK, Dimitri , CAMPBELL, Charles, E. , GROSS, Erik , SOMANI, Seema , DAI, Guangming
IPC分类号： A61B3/00
摘要： Methods, systems and software for determine an optical surface model for an optical tissue system using Fourier transformation algorithms. A method of reconstructing optical tissues of an eye comprises transmitting an image through the optical tissues of the eye. The surface gradients from the transmitted image are measured across the optical tissues of the eye. A Fourier transform algorithm is applied to the surface gradients to reconstruct an optical surface model that corresponds to the optical tissues of the eye.

10. 发明申请

WO2004112588A2 ITERATIVE FOURIER RECONSTRUCTION FOR LASER SURGERY AND OTHER OPTICAL APPLICATIONS 审中-公开
标题翻译：用于激光手术和其他光学应用的重复FOURIER重建
公开(公告)号：WO2004112588A2
公开(公告)日：2004-12-29
申请号：PCT/US2004/020733
申请日：2004-06-17
申请人： VISX, INCORPORATED , CHERNYAK, Dimitri , CAMPBELL, Charles, E. , GROSS, Erik , SOMANI, Seema , DAI, Guangming
发明人： CHERNYAK, Dimitri , CAMPBELL, Charles, E. , GROSS, Erik , SOMANI, Seema , DAI, Guangming
IPC分类号： A61B
CPC分类号： A61B3/1015 , G01J9/00
摘要： Methods, systems and software for determine an optical surface model for an optical tissue system using Fourier transformation algorithms. A method of reconstructing optical tissues of an eye comprises transmitting an image through the optical tissues of the eye. The surface gradients from the transmitted image are measured across the optical tissues of the eye. A Fourier transform algorithm is applied to the surface gradients to reconstruct an optical surface model that corresponds to the optical tissues of the eye.
摘要翻译：用于使用傅里叶变换算法确定光学组织系统的光学表面模型的方法，系统和软件。重建眼睛的光学组织的方法包括通过眼睛的光学组织传输图像。来自透射图像的表面梯度在眼睛的光学组织上测量。将傅里叶变换算法应用于表面梯度以重建对应于眼睛的光学组织的光学表面模型。

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