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1. 发明申请

WO2005033727A1 TIMING OF MRI DATA ACQUISITION INVOLVING IMPLANTABLE MEDICAL DEVICES 审中-公开
标题翻译：涉及可植入医疗器械的MRI数据采集时序
公开(公告)号：WO2005033727A1
公开(公告)日：2005-04-14
申请号：PCT/US2004/031749
申请日：2004-09-28
申请人： MEDTRONIC, INC. , ZEIJEMAKER, Volkert, A. , GOEDEKE, Steven, D.
发明人： ZEIJEMAKER, Volkert, A. , GOEDEKE, Steven, D.
IPC分类号： G01R33/567
CPC分类号： G01R33/5673 , A61N1/3718
摘要： The invention is directed to techniques in which magnetic resonance imaging (MRI) is coordinated with the operation of an implantable medical device (IMD). By using an IMD to sense conditions, MRI can be improved because the sensed conditions can accurately define timing for application of electromagnetic radiation bursts. Moreover, by applying stimulation pulses specifically to coordinate the electromagnetic radiation bursts, the MRI may also be improved. In one embodiment, a cardiac pacemaker is used to sense the ECG of the subject and transmit the ECG to the MRI scanner. Moreover, the pacemaker may be used to alter the heart frequency of the subject (e.g. induction of arrhythmia).
摘要翻译：本发明涉及其中磁共振成像（MRI）与可植入医疗装置（IMD）的操作协调的技术。通过使用IMD来感测条件，可以改善MRI，因为感测的条件可以准确地定义施加电磁辐射突发的定时。此外，通过特异地施加刺激脉冲来协调电磁辐射脉冲串，也可以改善MRI。在一个实施例中，使用心脏起搏器来感测对象的ECG并将ECG发送到MRI扫描仪。此外，起搏器可用于改变受试者的心脏频率（例如心律失常的诱发）。

2. 发明申请

WO2011136826A1 ACTIVE CIRCUIT MRI/EMI PROTECTION POWERED BY INTERFERING ENERGY FOR A MEDICAL STIMULATION LEAD AND DEVICE 审中-公开
标题翻译：有源电路通过干扰医疗刺激引线和器件的能量来实现MRI / EMI保护
公开(公告)号：WO2011136826A1
公开(公告)日：2011-11-03
申请号：PCT/US2010/049427
申请日：2010-09-20
申请人： MEDTRONIC, INC. , GOEDEKE, Steven D. , HAUBRICH, Gregory J. , WAHLSTRAND, John D.
发明人： GOEDEKE, Steven D. , HAUBRICH, Gregory J. , WAHLSTRAND, John D.
IPC分类号： A61N1/05 , A61N1/08 , A61N1/37 , A61N1/36
CPC分类号： A61N1/05 , A61N1/086 , A61N1/3605 , A61N1/3718
摘要： An implantable lead for use with a medical device (IMD) includes active circuits incorporated into the lead to reduce the creation of an induced current, or dissipate the induced current and heat created due to an induced current in the lead. The active circuits are powered by the magnetic resonant imaging energy or interfering magnetic or electrical fields. According to various embodiments, the lead and/or its components can be provided to reduce or dissipate a current and heat induced by various external magnetic or electrical fields.
摘要翻译：与医疗装置（IMD）一起使用的可植入引线包括并入导线中的有源电路，以减少感应电流的产生，或消散由于引线中的感应电流而产生的感应电流和热量。有源电路由磁共振成像能量或干扰磁场或电场供电。根据各种实施例，可以提供引线和/或其部件以减少或消散由各种外部磁场或电场引起的电流和热。

3. 发明申请

WO2007127648A3 SELECTIVELY IMPLEMENTABLE DIGITAL SIGNAL PROCESSING CIRCUIT FOR AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：一种可植入医疗设备的选择性数字信号处理电路
公开(公告)号：WO2007127648A3
公开(公告)日：2007-12-21
申请号：PCT/US2007066832
申请日：2007-04-18
申请人： MEDTRONIC INC , GILLBERG JEFFREY M , GOEDEKE STEVEN D
发明人： GILLBERG JEFFREY M , GOEDEKE STEVEN D
IPC分类号： A61N1/372 , A61N1/08 , A61N1/37 , A61N1/378 , G06F1/32
CPC分类号： A61N1/37 , A61B2560/0209 , A61N1/08 , A61N1/372 , A61N1/378
摘要： Embodiments of the invention include an implantable medical device having a digital signal processing circuit associated with an implantable medical device function. The digital signal processing circuit can be selectively implementable according to the clinical need of a patient. Embodiments of the invention also include methods of making and using such implantable medical devices.
摘要翻译：本发明的实施例包括具有与可植入医疗装置功能相关联的数字信号处理电路的可植入医疗装置。数字信号处理电路可以根据患者的临床需要选择性地实施。本发明的实施例还包括制造和使用这种可植入医疗装置的方法。

4. 发明申请

WO2013109365A1 VASOCONSTRICTOR FOR USE IN THE TREATMENT OF ABNORMAL UTERINE BLEEDING AND APPARATUS FOR DELIVERY THEREOF 审中-公开
标题翻译：用于治疗异常子宫切除术的血管造影剂及其输送装置
公开(公告)号：WO2013109365A1
公开(公告)日：2013-07-25
申请号：PCT/US2012/069257
申请日：2012-12-12
申请人： GOEDEKE, Steven D. , EUTENEUER, Charles L. , HEKTNER, Thomas K. , CROMPTON, David M.
发明人： GOEDEKE, Steven D. , EUTENEUER, Charles L. , HEKTNER, Thomas K. , CROMPTON, David M.
IPC分类号： A61K31/4174 , A61P7/04 , A61M25/00
CPC分类号： A61K31/4174 , A61F6/225 , A61F13/2074 , A61K9/0036 , A61M31/002
摘要： Method and apparatus (100, 161, 200, 215, 300, 400, 450, 500, 600, 650) are disclosed for applying a therapeutic amount of a non-systemic vasoconstrictor inside the uterus (12) to control abnormal uterine bleeding. The abnormal bleeding can be due to excessive menstrual blood flow, bleeding from a surgical procedure, postpartum bleeding or any other acute or chronic condition. The vasoconstrictor includes topical agents such as an alpha-adrenergic agonist, for example oxymetazoline. The delivery system (100, 200) can include a catheter having means for retaining position of a distal portion (102) within the uterus (12). A proximal portion (104) can extend outside of the body for coupling to a vasoconstrictor source, or alternatively, the proximal portion (104) can terminate within the vaginal canal (20) and include a docking port (154) for coupling to a source of vasoconstrictor that is inserted therein. In other embodiments, an applicator (161, 215, 300, 400, 450, 500, 600, 650) is disclosed that is positioned in fluid communication with the lumen of the cervix (24) and allows application of a vasoconstrictor therein.
摘要翻译：公开了用于在子宫（12）内施用治疗量的非系统性血管收缩剂以控制异常子宫出血的方法和装置（100,161,200,215,300,400,450,500,600,650）。异常出血可能是由于月经量过多，外科手术出血，产后出血或其他急性或慢性疾病。血管收缩剂包括局部剂，例如α-肾上腺素能激动剂，例如羟甲唑啉。输送系统（100,200）可以包括具有用于保持在子宫（12）内的远端部分（102）的位置的装置的导管。近端部分（104）可以延伸到身体的外部，用于联接到血管收缩源，或者替代地，近端部分（104）可以终止在阴道内（20）内，并且包括用于联接到源的对接端口（154）的血管收缩剂。在其它实施例中，公开了一种定位成与子宫颈（24）的内腔流体连通并且允许在其中施加血管收缩剂的施加器（161,215,300,400,450,500,600,650）。

5. 发明申请

WO2013090321A1 VASOCONSTRICTOR FOR USE IN THE TREATMENT OF ABNORMAL UTERINE BLEEDING 审中-公开
标题翻译：用于治疗异常子宫切除术的血管造影剂
公开(公告)号：WO2013090321A1
公开(公告)日：2013-06-20
申请号：PCT/US2012/069075
申请日：2012-12-12
申请人： GOEDEKE, Steven D.
发明人： GOEDEKE, Steven D.
IPC分类号： A61K31/4174 , A61K45/06 , A61K9/02 , A61F13/20 , A61P7/04
CPC分类号： A61K31/4174 , A61F6/225 , A61F13/2074 , A61K9/0036 , A61M31/002
摘要： Method and apparatus (10, 50) are disclosed for applying a therapeutic amount of a vasoconstrictor (20, 54) within the vaginal canal to control abnormal uterine bleeding. The abnormal bleeding can be due to excessive menstrual blood flow, bleeding from a surgical procedure, postpartum bleeding or any other acute or chronic condition. The vasoconstrictor (20, 54) includes topical agents such as an alpha-adrenergic agonist, for example oxymetazoline. The vasoconstrictor (20, 54) can be applied within the vaginal canal using any of many delivery apparatus. The vasoconstrictor (20, 54) can be included on a carrier member (10, 50) that is positioned in the vaginal canal and remains in place for a period of time, such as a tampon (12). In some embodiments, the carrier member (10, 50) can be a polymer ring (52) or other shape that is inserted in the upper portion of the vaginal canal, such as the fornix area.
摘要翻译：公开了用于在阴道内施用治疗量的血管收缩剂（20,54）以控制异常子宫出血的方法和装置（10,50）。异常出血可能是由于月经量过多，外科手术出血，产后出血或其他急性或慢性疾病。血管收缩剂（20,54）包括局部剂，例如α-肾上腺素能激动剂，例如羟甲唑啉。血管收缩剂（20,54）可以使用任何多种递送装置在阴道内施用。血管收缩剂（20,54）可以包含在位于阴道内的载体构件（10,50）上并保持一段时间的位置，例如卫生棉条（12）。在一些实施例中，载体构件（10,50）可以是聚合物环（52）或插入阴道的上部，例如穹窿区域的其他形状。

6. 发明申请

WO2012057873A1 PROTECTING AN IMPLANTABLE MEDICAL DEVICE FROM EFFECTS CAUSED BY AN INTERFERING RADIATION FIELD 审中-公开
标题翻译：由干扰辐射场引起的影响保护可植入医疗器械
公开(公告)号：WO2012057873A1
公开(公告)日：2012-05-03
申请号：PCT/US2011/034645
申请日：2011-04-29
申请人： MEDTRONIC. INC. , STANCER, Christopher C. , GOEDEKE, Steven D. , NOWAK, Michael E.
发明人： STANCER, Christopher C. , GOEDEKE, Steven D. , NOWAK, Michael E.
IPC分类号： A61N1/08 , H01P1/20 , A61N1/37 , A61N1/375 , A61N1/372
CPC分类号： A61N1/375 , A61N1/025 , A61N1/3718 , A61N1/37211 , A61N1/3754 , H01P1/20
摘要： Techniques are described for protecting an implantable medical device (IMD) from effects caused by interfering radiated fields. An IMD incorporating these techniques may include a telemetry conduction path that includes a first end electrically coupled to a telemetry antenna and a second end electrically coupled to a telemetry circuit disposed within a housing of the IMD. The IMD may further include a stub filter electrically coupled to the telemetry conduction path and configured to attenuate an interfering signal induced in the telemetry conduction path. The stub filter may include a dielectric and a conductor disposed within the dielectric. The conductor may include a first end electrically coupled to the telemetry conduction path and a second end configured in an open circuit configuration. The conductor may have an electrical length approximately equal to one-quarter wavelength of the interfering signal when propagating through the stub filter.
摘要翻译：描述了用于保护植入式医疗装置（IMD）免受由干扰辐射场引起的影响的技术。包含这些技术的IMD可以包括遥测传导路径，其包括电耦合到遥测天线的第一端和电耦合到设置在IMD的壳体内的遥测电路的第二端。 IMD还可以包括电耦合到遥测传导路径并被配置为衰减在遥测传导路径中感应的干扰信号的短截线滤波器。短截线过滤器可以包括电介质和布置在电介质内的导体。导体可以包括电耦合到遥测传导路径的第一端和以开路结构配置的第二端。当通过短截线过滤器传播时，导体可以具有大约等于干扰信号的四分之一波长的电长度。

7. 发明申请

WO2007127648A2 SELECTIVELY IMPLEMENTABLE DIGITAL SIGNAL PROCESSING CIRCUIT FOR AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于可移植医疗设备的可选择的可执行数字信号处理电路
公开(公告)号：WO2007127648A2
公开(公告)日：2007-11-08
申请号：PCT/US2007/066832
申请日：2007-04-18
申请人： MEDTRONIC, INC. , GILLBERG, Jeffrey M. , GOEDEKE, Steven D.
发明人： GILLBERG, Jeffrey M. , GOEDEKE, Steven D.
CPC分类号： A61N1/37 , A61B2560/0209 , A61N1/08 , A61N1/372 , A61N1/378
摘要： Embodiments of the invention include an implantable medical device having a digital signal processing circuit associated with an implantable medical device function. The digital signal processing circuit can be selectively implementable according to the clinical need of a patient. Embodiments of the invention also include methods of making and using such implantable medical devices.
摘要翻译：本发明的实施例包括具有与可植入医疗装置功能相关联的数字信号处理电路的可植入医疗装置。数字信号处理电路可以根据患者的临床需要选择性地实施。本发明的实施例还包括制造和使用这种可植入医疗装置的方法。

8. 发明申请

WO2005079908A3 IMPLANTABLE MEDICAL DEVICES WITH DUAL-MEMORY SUPPORT 审中-公开
标题翻译：具有双存储器支持的可植入医疗器械
公开(公告)号：WO2005079908A3
公开(公告)日：2007-04-19
申请号：PCT/US2005005154
申请日：2005-02-17
申请人： MEDTRONIC INC , GOEDEKE STEVEN D
发明人： GOEDEKE STEVEN D
IPC分类号： A61N1/372 , A61N1/375
CPC分类号： A61N1/37264 , A61N1/025 , A61N1/37211 , A61N1/37229
摘要： The invention is directed to implantable medical devices (IMDs) with dual-memory support. An IMD is designed to detect the presence or absence of a programmable non-volatile memory, such as flash memory. The IMD processor determines whether operation instructions reside in non-programmable non-volatile memory or in programmable non-volatile memory as a function of an output from a detector circuit.
摘要翻译：本发明涉及具有双存储器支持的可植入医疗装置（IMD）。 IMD被设计为检测可编程非易失性存储器（例如闪存）的存在或不存在。 IMD处理器根据检测器电路的输出确定操作指令是否位于非可编程非易失性存储器或可编程非易失性存储器中。

9. 发明申请

WO2005079908A2 IMPLANTABLE MEDICAL DEVICES WITH DUAL-MEMORY SUPPORT 审中-公开
标题翻译：具有双存储器支持的可植入医疗器械
公开(公告)号：WO2005079908A2
公开(公告)日：2005-09-01
申请号：PCT/US2005/005154
申请日：2005-02-17
申请人： MEDTRONIC, INC. , GOEDEKE, Steven, D.
发明人： GOEDEKE, Steven, D.
IPC分类号： A61N
CPC分类号： A61N1/37264 , A61N1/025 , A61N1/37211 , A61N1/37229
摘要： The invention is directed to implantable medical devices (IMDs) with dual-memory support. An IMD is designed to detect the presence or absence of a programmable non-volatile memory, such as flash memory. The IMD processor determines whether operation instructions reside in non-programmable non-volatile memory or in programmable non-volatile memory as a function of an output from a detector circuit.
摘要翻译：本发明涉及具有双存储器支持的可植入医疗装置（IMD）。 IMD被设计为检测可编程非易失性存储器（例如闪存）的存在或不存在。 IMD处理器根据检测器电路的输出确定操作指令是否位于非可编程非易失性存储器或可编程非易失性存储器中。

10. 发明申请

WO2005070498A1 DEVICE AND METHOD FOR REDUCING IMPLANTABLE DEFIBRILLATOR VOLUME 审中-公开
标题翻译：用于减少可植入的剔除器体积的装置和方法
公开(公告)号：WO2005070498A1
公开(公告)日：2005-08-04
申请号：PCT/US2005/001068
申请日：2005-01-12
申请人： MEDTRONIC, INC. , GOEDEKE, Steven, D. , PAPE, Forrest, C.M.
发明人： GOEDEKE, Steven, D. , PAPE, Forrest, C.M.
IPC分类号： A61N1/39
CPC分类号： A61N1/375 , A61N1/3968 , A61N1/3975
摘要： A battery/capacitor assembly for use in an implantable medical device comprises a battery and at least one capacitor housed in a unitary metal encasement. Either the battery, capacitor, or both may be coated with an insulating layer (e.g. plastic). In addition, a metallic layer may be disposed between the battery and the at least one capacitor.
摘要翻译：用于可植入医疗装置的电池/电容器组件包括电池和容纳在单一金属外壳中的至少一个电容器。电池，电容器或两者都可以涂覆有绝缘层（例如塑料）。此外，金属层可以设置在电池和至少一个电容器之间。

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