专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2018195468A2 DISPOSABLE SYSTEM FOR ANALYSIS OF HEMOSTATIC FUNCTION 审中-公开
公开(公告)号：WO2018195468A2
公开(公告)日：2018-10-25
申请号：PCT/US2018/028630
申请日：2018-04-20
申请人： HEMOSONICS, LLC , VIOLA, Francesco , HIGGINS, Timothy , HOMYK, Andrew , COREY, F. Scott , REGAN, Frank , WALKER, William F. , BRYANT, David , GIVENS, Thomas
发明人： VIOLA, Francesco , HIGGINS, Timothy , HOMYK, Andrew , COREY, F. Scott , REGAN, Frank , WALKER, William F. , BRYANT, David , GIVENS, Thomas
IPC分类号： G01N33/49
摘要： A disposable system, in some embodiments, includes a multi-channel or multi-chamber test cartridge device configured to operate with a testing system for evaluation of hemostasis in a subject by in vitro evaluation of a test sample from the subject. The disposable system, in some embodiments, is configured to interrogate the test sample to evaluate clot stiffness, strength, or other mechanical properties of the test sample to assess the function of various physiological processes occur during coagulation and/or dissolution of the resulting clot.

2. 发明申请

WO2018195468A3 DISPOSABLE SYSTEM FOR ANALYSIS OF HEMOSTATIC FUNCTION 审中-公开
公开(公告)号：WO2018195468A3
公开(公告)日：2018-10-25
申请号：PCT/US2018/028630
申请日：2018-04-20
申请人： HEMOSONICS, LLC , VIOLA, Francesco , HIGGINS, Timothy , HOMYK, Andrew , COREY, F. Scott , REGAN, Frank , WALKER, William F. , BRYANT, David , GIVENS, Thomas
发明人： VIOLA, Francesco , HIGGINS, Timothy , HOMYK, Andrew , COREY, F. Scott , REGAN, Frank , WALKER, William F. , BRYANT, David , GIVENS, Thomas
IPC分类号： G01N33/49
摘要： A disposable system, in some embodiments, includes a multi-channel or multi-chamber test cartridge device configured to operate with a testing system for evaluation of hemostasis in a subject by in vitro evaluation of a test sample from the subject. The disposable system, in some embodiments, is configured to interrogate the test sample to evaluate clot stiffness, strength, or other mechanical properties of the test sample to assess the function of various physiological processes occur during coagulation and/or dissolution of the resulting clot.

3. 发明申请

WO0101152A9 METHOD AND APPARATUS FOR PRESENTING THROMBOSIS AND HEMOSTASIS ASSAY DATA 审中-公开
标题翻译：用于提供血栓形成和HEMOSTASIS测定数据的方法和装置
公开(公告)号：WO0101152A9
公开(公告)日：2002-05-02
申请号：PCT/US0018310
申请日：2000-06-30
申请人： AKZO NOBEL NV , GIVENS THOMAS B , BRAUN PAUL , BECK LISA
发明人： GIVENS THOMAS B , BRAUN PAUL , BECK LISA
IPC分类号： G01N33/86 , G01N33/49 , G01N33/68 , G06F19/00
CPC分类号： G01N33/4905 , G01N33/86 , G01N2800/226 , G01N2800/385 , G06F19/324 , G16H10/40 , G16H10/60 , G16H50/20
摘要： A method is disclosed for presenting data from an assay relating to thrombosis-hemostasis on an unknown sample (103), and data from a plurality of assays relating to thrombosis-hemostasis from known sample populations. Data is provided from at least one time dependent measurement profile for each of a plurality of known blood samples and a respective property over time is measured so as to derive at least one time-dependent measurement (101) for an unknown blood sample (103). Data from these steps are transformed to one or more predictor variables (110) from which a topological feature map (113) is created which has spatial locations that correspond to intrinsic features of the predictor variables (110). A determination is made of the position on the map (113) of the unknown sample (103) corresponding to its set of predictor variables (110) and then a presentation is made of the data from the unknown blood sample time-dependent measurement profile (101) relative to the data from the known blood sample time-dependent measurement profile.
摘要翻译：公开了一种用于从与未知样品（103）上的血栓形成止血有关的测定中提供数据的方法，以及与来自已知样品群体的血栓形成止血有关的多个测定的数据。从多个已知血液样本中的每一个的至少一个时间依赖性测量轮廓提供数据，并测量随时间的相应属性，以便为未知血液样品（103）导出至少一个时间依赖性测量（101）。来自这些步骤的数据被转换成一个或多个预测变量（110），从中创建拓扑特征图（113），其具有对应于预测变量（110）的固有特征的空间位置。确定对应于其预测变量组（110）的未知样本（103）的地图（113）上的位置，然后从来自未知血液样本时间依赖性测量轮廓的数据（ 101）相对于来自已知血液样本时间依赖性测量轮廓的数据。

4. 发明申请

WO1996041291A1 A METHOD AND APPARATUS FOR PREDICTING THE PRESENCE OF CONGENITAL AND ACQUIRED IMBALANCES AND THERAPEUTIC CONDITIONS 审中-公开
标题翻译：一种用于预测浓度和收集的不平衡和治疗条件的方法和装置
公开(公告)号：WO1996041291A1
公开(公告)日：1996-12-19
申请号：PCT/US1996008905
申请日：1996-06-05
申请人： AKZO NOBEL N.V. , GIVENS, Thomas, B. , BRAUN, Paul , FISCHER, Timothy, J.
发明人： AKZO NOBEL N.V.
IPC分类号： G06F19/00
CPC分类号： G01N33/4905 , C07K16/18 , G01N33/86 , G01N35/00 , G01N2800/226 , G01N2800/385 , G06F19/00 , G16H10/40 , G16H10/60 , G16H50/20 , G16H50/50
摘要： A method and apparatus are disclosed for predicting the presence of at least one congenital or acquired imbalance or therapeutic condition associated with thrombosis/hemostasis from at least one time-dependent measurement profile, (Figs. 3-6). At least one time-dependent measurement on an unknown sample is performed and a respective property of said sample is measured over time so as to derive a time-dependent measurement profile, (Figs. 3-6). A set of a plurality of predictor variables are defined which sufficiently define the data of the time-dependent measurement profile, (Fig. 13). A model is then derived that represents the relationship between the congenital or acquired imbalance or therapeutic condition, and the set of predictor variables. Subsequently, the model is utilized to predict the existence of the congenital or acquired imbalance or therapeutic condition in the unknown sample.
摘要翻译：公开了一种用于从至少一个时间依赖性测量轮廓预测与血栓形成/止血相关的至少一种先天性或获得性不平衡或治疗状况的存在的方法和装置（图3-6）。对未知样品进行至少一次时间依赖性测量，并且随时间测量所述样品的相应性质，从而导出时间依赖性测量分布（图3-6）。定义一组多个预测变量，其充分地限定了时间依赖性测量轮廓的数据（图13）。然后导出代表先天或获得性不平衡或治疗条件之间的关系的模型以及预测变量的集合。随后，该模型用于预测未知样本中先天性或获得性不平衡或治疗条件的存在。

5. 发明申请

WO1995005590A1 METHOD AND INSTRUMENT FOR AUTOMATICALLY PERFORMING ANALYSIS RELATING TO THROMBOSIS AND HEMOSTASIS 审中-公开
标题翻译：自动执行与血栓形成和血栓形成相关的分析方法和仪器
公开(公告)号：WO1995005590A1
公开(公告)日：1995-02-23
申请号：PCT/US1994009226
申请日：1994-08-16
申请人： AKZO NOBEL N.V. , FISCHER, Timothy, J. , CALLAHAN, Janet, B. , BRAUN, Paul, J. , GIVENS, Thomas, B. , HULETTE, William, C. , HOFFMAN, Julie, F. , LINK, John, G. , SWOPE, Charles, H.
发明人： AKZO NOBEL N.V.
IPC分类号： G01N01/28
CPC分类号： G01N35/00693 , G01N33/4905 , G01N35/00712 , G01N35/0092 , G01N2035/00366 , G01N2035/00702 , G01N2035/0093
摘要： This invention relates to a novel, fully automated spectrophotometric analyzer and method used for testing blood samples in the clinical laboratory for thrombosis and hemostasis properties. The analyzer tests samples in a fully randomized format, and is fully automated in the areas of specimen handling, sample preparation, optical inspection, data analysis and total quality control for imprecision and bias.
摘要翻译：本发明涉及一种新型全自动分光光度分析仪和用于在临床实验室检测血液血栓形成和止血性质的血液样品的方法。分析仪以完全随机格式对样品进行测试，并在样品处理，样品制备，光学检测，数据分析和不精确和偏倚的全面质量控制领域完全自动化。

6. 发明申请

WO1994002828A1 CASSETTE AND CUVETTE LOADING MECHANISM 审中-公开
标题翻译： CASSETTE和CUVETTE加载机制
公开(公告)号：WO1994002828A1
公开(公告)日：1994-02-03
申请号：PCT/US1993006811
申请日：1993-07-21
申请人： AKZO N.V. , LEWIS, Gregory, D. , ROBERTS, Roger, G. , GIVENS, Thomas, B.
发明人： AKZO N.V.
IPC分类号： G01N01/28
CPC分类号： B01L9/00 , B01L9/06 , G01N21/13 , G01N2035/0465 , Y10T436/113332 , Y10T436/114165
摘要： A cassette for storing and dispensing cuvettes comprising an enclosable frame (34) defining an interior volume for storing cuvettes. The frame (34) includes a removable cover (38) to aid in loading a plurality of cuvettes into the cassette. The frame (34) also includes a sidewall having a pivotally mounted door (40) for pivoting between a closed position and an open position for dispensing the cuvettes from the cassette. A locking mechanism (46, 48) for locking the door in the closed position to avoid inadvertent dispensing of cuvettes.
摘要翻译：一种用于存储和分配比色皿的盒，包括限定用于存储比色皿的内部容积的可封闭框架（34）。框架（34）包括可移除的盖（38），以帮助将多个比色杯装载到盒中。框架（34）还包括具有枢转安装的门（40）的侧壁，用于在关闭位置和用于从盒中分配比色杯的打开位置之间枢转。一种用于将门锁定在关闭位置以避免意外分配比色杯的锁定机构（46,48）。

7. 发明申请

WO1991008462A1 CUVETTE AND LINEAR DRIVE MECHANISM THEREFOR 审中-公开
标题翻译： CUVETTE和线性驱动机制
公开(公告)号：WO1991008462A1
公开(公告)日：1991-06-13
申请号：PCT/US1990006990
申请日：1990-11-30
申请人： AKZO N.V. , KARP, Joseph, George , GIVENS, Thomas, Beecher , LINK, John, Glenn
发明人： AKZO N.V.
IPC分类号： G01N21/03
CPC分类号： G01N21/03 , G01N35/026 , G01N35/04 , G01N2035/0413 , G01N2035/0487
摘要： A cuvette (10) for use in an optical instrument which includes a linear drive mechanism formed of a lead screw (30) for positioning the cuvette (10) along a linear path in the instrument. The cuvette has a body including at least one reaction well (14A-14D) and an engaging feature (24) for operatively engaging the threads of the lead screw (30) so the cuvette can be positioned along the linear path of the instrument. Preferably the reaction wells (14A-14D) have a trapezoïd-shape cross section in a plane parallel to the optical path of the instrument in order to maximize the optical viewing area.

8. 发明授权

US1611832A Combination vacuum tank and registering device 失效
公开(公告)号：US1611832A
公开(公告)日：1926-12-21
申请号：US75604124
申请日：1924-12-15
申请人： GIVENS THOMAS T
发明人： GIVENS THOMAS T
IPC分类号： B60K15/06
CPC分类号： B60K15/061 , Y10T74/18896

9. 发明授权

US1589068A Combination vacuum tank and registering device 失效
标题翻译：组合真空罐和配准装置
公开(公告)号：US1589068A
公开(公告)日：1926-06-15
申请号：US648125
申请日：1925-02-02
申请人： GIVENS THOMAS T
发明人： GIVENS THOMAS T
IPC分类号： F02M37/02
CPC分类号： F02M37/02

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式