专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

EP0865276A4 POLYAMINE DERIVATIVES OF 1-AMINOINDAN 失效
标题翻译：聚氨基甲酸乙酯氨基酸
公开(公告)号：EP0865276A4
公开(公告)日：2003-07-30
申请号：EP96923658
申请日：1996-07-05
申请人： GILAD GAD , GILAD VARDA
发明人： GILAD GAD , GILAD VARDA , STERLING JEFFREY , HERZIG YAACOV , LERNER DAVID , VEINBERG ALEX , MILMAN ISAAC , FINKELSTEIN NINA
IPC分类号： A61K31/135 , A61K31/155 , C07C211/42 , C07C233/41 , C07C279/12 , A61K31/15 , C07C243/20 , C07C247/14 , C07C281/16
CPC分类号： C07C279/12 , A61K31/135 , A61K31/155 , C07C211/42 , C07C233/41 , C07C2602/24

2. 发明公开

EP0865276A1 POLYAMINE DERIVATIVES OF 1-AMINOINDAN 失效
标题翻译：多胺我氨基二氢化茚
公开(公告)号：EP0865276A1
公开(公告)日：1998-09-23
申请号：EP96923658.0
申请日：1996-07-05
申请人： Gilad, Gad , Gilad, Varda
发明人： GILAD, Gad , GILAD, Varda , STERLING, Jeffrey , HERZIG, Yaacov , LERNER, David , VEINBERG, Alex , MILMAN, Isaac , FINKELSTEIN, Nina
IPC分类号： A61K31 , C07C211 , C07C233 , C07C279
CPC分类号： C07C279/12 , A61K31/135 , A61K31/155 , C07C211/42 , C07C233/41 , C07C2602/24
摘要： A compound of general formula (I), wherein n is 1 or 2; R1 and R2 are each independently hydrogen, hydroxy, substituted or unsubstituted C1-4 alkyl, substituted or unsubstituted C1-4 alkoxy or halogeno; R5 is hydrogen, substituted or unsubstituted C1-4 alkyl, amino or NR6R7; R3, R4, R6 and R7 are each independently hydrogen or (CH2)m-[NH(CH2)x]y-NHR11 wherein m is from 0-5, y is from 0-5 and each x is independently from 1-5 and R11 is hydrogen or C(NH)NH2; provided that when R3 and R4 are both hydrogen, R5 is amino or NR6R7; pharmaceutically acceptable salts and optically active isomers thereof.

3. 发明专利

IL122836D0 Polyamine derivatives of 1-aminoindan 未知
公开(公告)号：IL122836D0
公开(公告)日：1998-08-16
申请号：IL12283696
申请日：1996-07-05
申请人： GILAD GAD , GILAD VARDA
IPC分类号： A61K31/135 , A61K31/155 , C07C211/42 , C07C233/41 , C07C279/12 , C07C
摘要： A compound of general formula I (I) wherein n is 1 or 2; R1 and R2 are each independently hydrogen, hydroxy, substituted or unsubstituted C1-4 alkyl, substituted or unsubstituted C1-4 alkoxy or halogeno; R5 is hydrogen, substituted or unsubstituted C1-4 alkyl, amino or NR6R7; R3, R4, R6 and R7 are each independently hydrogen or (CH2)m-[NH(CH2)x]y-NHR11 wherein m is from 0-5, y is from 0-5 and each x is independently from 1-5 and R11 is hydrogen or C(NH)NH2; provided that when R3 and R4 are both hydrogen, R5 is amino or NR6R7; pharmaceutically acceptable salts and optically active isomers thereof.

4. 发明申请

WO2010030470A1 AGMATINE CONTAINING DIETARY SUPPLEMENTS, NUTRACEUTICALS, AND FOODS 审中-公开
标题翻译：含有膳食补充剂，营养物和食品的食品
公开(公告)号：WO2010030470A1
公开(公告)日：2010-03-18
申请号：PCT/US2009/054013
申请日：2009-08-17
申请人： GILAD, Gad, M. , GILAD, Varda, H.
发明人： GILAD, Gad, M. , GILAD, Varda, H.
IPC分类号： A23L1/305 , A23L2/52 , A61P25/02 , A23K1/16 , A61K31/155
CPC分类号： A23K20/142 , A23K20/147 , A23L2/52 , A23L33/17 , A61K31/155
摘要： The invention is dietary supplements, nutraceutical compositions, and medical foods that have cytoprotective and health promoting effects. The compositions contain an effective amount of dietary agmatine as a cytoprotective ingredient consisting of nutraceutical acceptable salts thereof. The compositions may contain agmatine alone or in combination with other dietary ingredients having health promoting effects. The compositions can be prepared with dietary accepted excipients as lubricants, glidants, sorbants, and disintegrants, and compatible forms of carriers, including but not limited to, powders, tablets, capsules, soft gelatin capsule, controlled release capsules and tablets, lozenges and chewable preparations, liquid suspensions, suspensions in an edible supporting matrix or foodstuff and oral rehydration solutions, to enable consumption of said compositions.
摘要翻译：本发明是具有细胞保护和健康促进作用的膳食补充剂，营养组合物和医疗食品。组合物含有有效量的膳食丁胺作为由其营养药物可接受的盐组成的细胞保护成分。组合物可以单独使用丁胺或与具有健康促进作用的其它膳食成分组合。组合物可以用膳食公认的赋形剂制备为润滑剂，助流剂，吸附剂和崩解剂，以及载体的相容形式，包括但不限于粉末，片剂，胶囊，软明胶胶囊，控释胶囊和片剂，锭剂和咀嚼物制剂，液体悬浮液，可食用支持基质中的悬浮液或食品和口服补液溶液，以使所述组合物能够消耗。

5. 发明申请

WO2011094458A1 AGMATINE CONTAINING DIETARY SUPPLEMENTS, NUTRACEUTICALS AND FOODS 审中-公开
标题翻译：含有膳食补充剂，营养食品的食品
公开(公告)号：WO2011094458A1
公开(公告)日：2011-08-04
申请号：PCT/US2011/022792
申请日：2011-01-27
申请人： GILAD, Gad , GILAD, Varda
发明人： GILAD, Gad , GILAD, Varda
IPC分类号： A23L1/305
CPC分类号： A61K31/155 , A23C9/13 , A23K20/142 , A23K20/147 , A23L2/52 , A23L33/10 , A23L33/17 , A23V2002/00 , A61K45/06
摘要： The invention is dietary supplements, nutraceutical compositions, medical foods, and animal feeds that have cytoprotective (cell and tissue protection) and health promoting effects. The compositions contain a high dose range of agmatine and nutraceutical acceptable salts thereof as dietary fortification for providing effective long-term cytoprotection and affording for soft stool. The compositions may contain agmatine alone or in combination with other dietary ingredients having health promoting effects. The compositions can be prepared with dietary accepted excipients and compatible forms of carriers, including but not limited to, powders, tablets, capsules, controlled release carriers, lozenges and chewable preparations, liquid suspensions, suspensions in an edible supporting matrix or foodstuff and oral rehydration solutions, to enable consumption of said compositions..
摘要翻译：本发明是具有细胞保护（细胞和组织保护）和健康促进作用的膳食补充剂，营养保健组合物，医疗食品和动物饲料。该组合物含有高剂量范围的胍丁胺及其营养药物可接受的盐作为用于提供有效的长期细胞保护并提供软粪便的饮食强化。组合物可以单独使用丁胺或与具有健康促进作用的其它膳食成分组合。组合物可以用膳食公认的赋形剂和相容形式的载体制备，包括但不限于粉末，片剂，胶囊，控释载体，锭剂和咀嚼制剂，液体悬浮液，可食用支持基质或食品中的悬浮液和口服补液解决方案，以使消费所述组合物。

6. 发明申请

WO1997002027A1 POLYAMINE DERIVATIVES OF 1-AMINOINDAN 审中-公开
标题翻译： 1-氨基茚的聚胺衍生物
公开(公告)号：WO1997002027A1
公开(公告)日：1997-01-23
申请号：PCT/US1996011318
申请日：1996-07-05
申请人： TEVA PHARMACEUTICAL INDUSTRIES, LTD. , GILAD, Gad , GILAD, Varda , STERLING, Jeffrey , HERZIG, Yaacov , LERNER, David , VEINBERG, Alex , MILMAN, Isaac , FINKELSTEIN, Nina
发明人： TEVA PHARMACEUTICAL INDUSTRIES, LTD.
IPC分类号： A61K31/15
CPC分类号： C07C279/12 , A61K31/135 , A61K31/155 , C07C211/42 , C07C233/41 , C07C2602/24
摘要： A compound of general formula (I), wherein n is 1 or 2; R1 and R2 are each independently hydrogen, hydroxy, substituted or unsubstituted C1-4 alkyl, substituted or unsubstituted C1-4 alkoxy or halogeno; R5 is hydrogen, substituted or unsubstituted C1-4 alkyl, amino or NR6R7; R3, R4, R6 and R7 are each independently hydrogen or (CH2)m-[NH(CH2)x]y-NHR11 wherein m is from 0-5, y is from 0-5 and each x is independently from 1-5 and R11 is hydrogen or C(NH)NH2; provided that when R3 and R4 are both hydrogen, R5 is amino or NR6R7; pharmaceutically acceptable salts and optically active isomers thereof.
摘要翻译：通式（I）的化合物，其中n为1或2; R 1和R 2各自独立地为氢，羟基，取代或未取代的C 1-4烷基，取代或未取代的C 1-4烷氧基或卤素; R5是氢，取代或未取代的C1-4烷基，氨基或NR6R7; R3，R4，R6和R7各自独立地为氢或（CH2）m- [NH（CH2）x] y-NHR11，其中m为0-5，y为0-5，并且各x独立地为1-5 和R 11是氢或C（NH）NH 2; 条件是当R3和R4都是氢时，R5是氨基或NR6R7; 其药学上可接受的盐和旋光异构体。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式