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1. 发明授权

US6140105A Cellulose-producing bacteria 失效
标题翻译：纤维素生产菌
公开(公告)号：US6140105A
公开(公告)日：2000-10-31
申请号：US359812
申请日：1999-07-23
申请人： Kunihiko Watanabe , Hiroshi Takemura , Mari Tabuchi , Naoki Tahara , Hiroshi Toyosaki , Yasushi Morinaga , Takayasu Tsuchida , Hisato Yano , Fumihiro Yoshinaga
发明人： Kunihiko Watanabe , Hiroshi Takemura , Mari Tabuchi , Naoki Tahara , Hiroshi Toyosaki , Yasushi Morinaga , Takayasu Tsuchida , Hisato Yano , Fumihiro Yoshinaga
IPC分类号： C12P19/04 , C12N1/20
CPC分类号： C12R1/02 , C12P19/04 , C12R1/01 , Y10S435/823
摘要： Novel cellulose-producing bacteria including one capable of producing of a bacterial cellulose having a weight-average degree of polymerization in terms of polystyrene of 1.6.times.10.sup.4 or above, one capable of producing a bacterial cellulose containing a small amount of the fraction with low degrees of polymerization, one producing a Bingham polysaccharide as a by-product, and one producing a small amount of water-soluble polysaccharide; a method for the production of bacterial cellulose, which comprises culturing these cellulose-producing bacteria; and bacterial cellulose thus obtained.
摘要翻译：新型的纤维素生成菌，包括能够生产聚苯乙烯换算重量平均聚合度为1.6×10 4以上的细菌纤维素的纤维素生成菌，能够生产含少量低分子量的细菌纤维素的细菌纤维素聚合，一种生产宾汉多糖作为副产物，一种生产少量水溶性多糖; 一种生产细菌纤维素的方法，包括培养这些纤维素生产菌; 和由此获得的细菌纤维素。

2. 发明授权

US3962034A Method for producing S-adenosylmethionine or methylthioadenosine by yeast 失效
标题翻译： YEAST生产S-腺苷甲基或甲基二氢叶酸的方法
公开(公告)号：US3962034A
公开(公告)日：1976-06-08
申请号：US527071
申请日：1974-11-25
申请人： Takayasu Tsuchida , Fumihiro Yoshinaga , Shinji Okumura
发明人： Takayasu Tsuchida , Fumihiro Yoshinaga , Shinji Okumura
IPC分类号： C12P19/40 , C12D13/06
CPC分类号： C12P19/40 , Y10S435/911 , Y10S435/921 , Y10S435/93 , Y10S435/938 , Y10S435/94
摘要： S-adenosylmethionine and methylthioadenosine are produced in the culture medium of yeast grown in a media containing L-methionine.

3. 发明授权

US6132998A Process for continuously preparing bacterial cellulose 失效
标题翻译：连续制备细菌纤维素的方法
公开(公告)号：US6132998A
公开(公告)日：2000-10-17
申请号：US981495
申请日：1998-02-26
申请人： Takaaki Naritomi , Tohru Kouda , Michi Naritomi , Hisato Yano , Fumihiro Yoshinaga
发明人： Takaaki Naritomi , Tohru Kouda , Michi Naritomi , Hisato Yano , Fumihiro Yoshinaga
IPC分类号： C08B37/00 , C12P19/04 , C12R1/02 , C08B15/00 , C12P19/00
CPC分类号： C12P19/04
摘要： An object of the present invention is to obtain the high production rate and yield of BC. The present invention relates to a process for the production of cellulosic material at a production rate of 0.4 g/L/hr or more, which comprises culturing cellulose-producing bacteria while maintaining the concentration of the residual sugars in a culture broth at 20 g/L or less, and to a process for the production of cellulosic material at a production rate of 0.4 g/L/hr or more, which comprises culturing cellulose-producing bacteria in a culture medium containing a factor which improves an apparent affinity of substrate for sugars.
摘要翻译： PCT No.PCT / JP97 / 01713 Sec。 371日期1998年2月26日 102（e）日期1998年2月26日PCT提交1997年5月21日PCT公布。 WO97 / 44477 PCT公开号日期1997年11月27日本发明的目的是获得BC的高生产率和产量。本发明涉及以0.4g / L / hr以上的生产速度生产纤维素材料的方法，该方法包括培养纤维素生产细菌，同时保持培养液中残留糖的浓度为20g / L以下，生产速度为0.4g / L / hr以上的纤维素材料的制造方法，其特征在于，在含有提高基材表观亲和性的因素的培养基中培养纤维素生成菌糖。

4. 发明授权

US6110712A Cellulose-producing bacteria 失效
标题翻译：纤维素生产菌
公开(公告)号：US6110712A
公开(公告)日：2000-08-29
申请号：US274470
申请日：1999-03-23
申请人： Takayasu Tsuchida , Naoto Tonouchi , Akira Seto , Yukiko Kojima , Masanobu Matsuoka , Fumihiro Yoshinaga
发明人： Takayasu Tsuchida , Naoto Tonouchi , Akira Seto , Yukiko Kojima , Masanobu Matsuoka , Fumihiro Yoshinaga
IPC分类号： C12P19/04 , C12R1/02 , C12N1/20
CPC分类号： C12R1/02 , C12P19/04 , Y10S435/823
摘要： This invention relates to a microorganism that is capable of producing a cellulosic product (referred to hereinafter as a "cellulose-producing bacterium") and belongs to a novel subspecies which is substantialy negative or very slightly positive in oxidation of acetates and lactates. This invention also relates to novel saccharide analog-resistant strains, amino acid analog-resistant strains and levan sucrase-defective strains. Further, this invention relates to a method for the production of cellulosic material (bacterial cellulose:"BC"), which comprises culturing these novel bactria and to bacterial cellulose which may be thus obtained. A larger amount of bacterial cellulose may be produced by culturing Acetobacter xylinum subsp. nonacetoxidans, the present resistant strains and the levan sucrase-defective strains, which have been derived and bred from the cellulose-producing bacteria, than by culturing the BPR 2001 strain in the medium containing especially sucrose or glucose as carbon sources.
摘要翻译： PCT No.PCT / JP87 / 00514 Sec。 371日期1998年2月3日 102（e）日1998年2月3日PCT 1997年2月24日提交PCT本发明涉及能够生产纤维素产品（以下称为“纤维素生产细菌”）的微生物，属于新亚种，在乙酸盐和乳酸盐的氧化中具有显着的负性或非常微量的阳性。本发明还涉及新型糖类似物抗性菌株，氨基酸类似物抗性菌株和levan蔗糖酶缺陷菌株。此外，本发明涉及一种生产纤维素材料（细菌纤维素“BC”）的方法，该方法包括培养这些新型细菌和可得到的细菌纤维素。可以通过培养木醋杆菌（Subst。）来生产更多的细菌纤维素。通过在特别是蔗糖或葡萄糖作为碳源的培养基中培养BPR 2001菌株，从纤维素生产细菌中衍生和繁殖的本发明的耐药菌株，本发明的抗性菌株和levan蔗糖酶缺陷菌株。

5. 发明授权

US5962277A Cellulose-producing bacteria 失效
标题翻译：纤维素生产菌
公开(公告)号：US5962277A
公开(公告)日：1999-10-05
申请号：US930587
申请日：1998-01-09
申请人： Kunihiko Watanabe , Hiroshi Takemura , Mari Tabuchi , Naoki Tahara , Hiroshi Toyosaki , Yasushi Morinaga , Takayasu Tsuchida , Hisato Yano , Fumihiro Yoshinaga
发明人： Kunihiko Watanabe , Hiroshi Takemura , Mari Tabuchi , Naoki Tahara , Hiroshi Toyosaki , Yasushi Morinaga , Takayasu Tsuchida , Hisato Yano , Fumihiro Yoshinaga
IPC分类号： C12P19/04 , C12N1/20
CPC分类号： C12R1/02 , C12P19/04 , C12R1/01 , Y10S435/823
摘要： Novel cellulose-producing bacteria including one capable of producing of a bacterial cellulose having a weight-average degree of polymerization in terms of polystyrene of 1.6.times.10.sup.4 or above, one capable of producing a bacterial cellulose containing a small amount of the fraction with low degrees of polymerization, one producing a Bingham polysaccharide as a by-product, and one producing a small amount of water-soluble polysaccharide; a method for the production of bacterial cellulose, which comprises culturing these cellulose-producing bacteria; and bacterial cellulose thus obtained.
摘要翻译： PCT No.PCT / JP96 / 00481 Sec。 371日期1998年1月9日 102（e）日期1998年1月9日PCT 1996年2月29日PCT PCT。出版物WO96 / 33222 日期：1996年10月24日新型的纤维素生成菌包括能够生产聚苯乙烯换算重量平均聚合度为1.6×10 4以上的细菌纤维素的纤维素生产菌，能够生产含有少量产生低聚合度的馏分，一种产生宾汉多糖作为副产物，一种产生少量的水溶性多糖; 一种生产细菌纤维素的方法，包括培养这些纤维素生产菌; 和由此获得的细菌纤维素。

6. 发明授权

US06818434B2 Cellulose-producing bacteria 失效
标题翻译：纤维素生产菌
公开(公告)号：US06818434B2
公开(公告)日：2004-11-16
申请号：US10162073
申请日：2002-06-05
申请人： Kunihiko Watanabe , Hiroshi Takemura , Mari Tabuchi , Naoki Tahara , Hiroshi Toyosaki , Yasushi Morinaga , Takayasu Tsuchida , Hisato Yano , Fumihiro Yoshinaga
发明人： Kunihiko Watanabe , Hiroshi Takemura , Mari Tabuchi , Naoki Tahara , Hiroshi Toyosaki , Yasushi Morinaga , Takayasu Tsuchida , Hisato Yano , Fumihiro Yoshinaga
IPC分类号： C12P1904
CPC分类号： C12R1/02 , C12P19/04 , C12R1/01 , Y10S435/823
摘要： Novel cellulose-producing bacteria including one capable of producing of a bacterial cellulose having a weight-average degree of polymerization in terms of polystyrene of 1.6×104 or above, one capable of producing a bacterial cellulose containing a small amount of the fraction with low degrees of polymerization, one producing a Bingham polysaccharide as a by-product, and one producing a small amount of water-soluble polysaccharide; a method for the production of bacterial cellulose, which comprises culturing these cellulose-producing bacteria; and bacterial cellulose thus obtained.
摘要翻译：新型的纤维素生成菌，包括能够生产聚苯乙烯换算重量平均聚合度为1.6×10 4以上的细菌纤维素的纤维素生产菌，能够生产含有少量馏分的细菌纤维素的细菌纤维素，低聚合度，一种生产宾汉多糖作为副产物，一种产生少量水溶性多糖; 一种生产细菌纤维素的方法，包括培养这些纤维素生产菌; 和由此获得的细菌纤维素。

7. 发明授权

US06316251B1 Gene, group of genes, and novel &bgr;-gluclosidase 失效
标题翻译：基因，基因组和新型β-葡糖苷酶
公开(公告)号：US06316251B1
公开(公告)日：2001-11-13
申请号：US09147236
申请日：1999-04-08
申请人： Naoto Tonouchi , Takayasu Tsuchida , Fumihiro Yoshinaga , Naoki Tahara , Hisato Yano , Takahisa Hayashi
发明人： Naoto Tonouchi , Takayasu Tsuchida , Fumihiro Yoshinaga , Naoki Tahara , Hisato Yano , Takahisa Hayashi
IPC分类号： C12N1563
CPC分类号： C12N9/1059 , C12N9/2445 , C12N15/52 , C12Y302/01004 , C12Y302/01021
摘要： An object of the present invention is to provide novel genes and gene group involved in cellulose synthesis of microorganisms. The present invention relates to a gene group encoding cellulase, cellulose synthase complex, &bgr;-glucosidase and the like, and to novel &bgr;-glucosidase.
摘要翻译：本发明的目的是提供涉及微生物纤维素合成的新基因和基因组。本发明涉及编码纤维素酶，纤维素合成酶复合物，β-葡糖苷酶等的基因组和新型β-葡糖苷酶。

8. 发明授权

US6013490A Method for cultivating apparatus for the production of bacterial cellulose in an aerated and agitated culture 失效
标题翻译：培养在充气和搅拌培养物中生产细菌纤维素的装置的方法
公开(公告)号：US6013490A
公开(公告)日：2000-01-11
申请号：US824096
申请日：1997-03-25
申请人： Tohru Kouda , Yasuhisa Nagata , Hisato Yano , Fumihiro Yoshinaga
发明人： Tohru Kouda , Yasuhisa Nagata , Hisato Yano , Fumihiro Yoshinaga
IPC分类号： C12M1/04 , C12P19/12 , C08B1/00
CPC分类号： C12P19/12 , C12M27/06
摘要： A method for the production of a bacterial cellulose by cultivating a cellulose-producing bacteria for at least a certain period of time under such an apparatus condition that an oxygen-transfer coefficient (K.sub.L a) is about 25 to about 50/hr, said K.sub.L a is determined by using a simulated suspension containing 2% by weight of BC and having a plastic viscosity of 15 to 20 poise.
摘要翻译：在氧传递系数（KLa）为约25〜约50 /小时的设备条件下，通过在至少一定时间内培养纤维素生成细菌来生产细菌纤维素的方法，所述KLa为通过使用含有2重量％的BC并具有15至20泊的塑性粘度的模拟悬浮液来确定。

9. 发明授权

US4371613A Method for producing purine arabinosides 失效
标题翻译：嘌呤阿拉伯糖苷生产方法
公开(公告)号：US4371613A
公开(公告)日：1983-02-01
申请号：US930046
申请日：1978-08-01
申请人： Takashi Utagawa , Takeshi Miyoshi , Hirokazu Morisawa , Akihiro Yamazaki , Fumihiro Yoshinaga , Koji Mitsugi
发明人： Takashi Utagawa , Takeshi Miyoshi , Hirokazu Morisawa , Akihiro Yamazaki , Fumihiro Yoshinaga , Koji Mitsugi
IPC分类号： C07H19/16 , C12P19/40 , C12P19/32
CPC分类号： C12P19/40 , C07H19/16
摘要： Purine-arabinosides and a method for making purine-arabinosides are disclosed. The method comprises contacting an arabinose donor and a purine source in the presence of an effective amount of enzyme produced by a bacterium and capable of transarabinosylation from the arabinose donor to the purine source, whereby a 9-(.beta.-D-arabinofuranosyl)-purine is produced.
摘要翻译：公开了嘌呤 - 阿拉伯糖苷和制备嘌呤 - 阿拉伯糖苷的方法。该方法包括在有效量的由细菌产生并能够从阿拉伯糖供体转运到嘌呤源的阿拉伯糖基化反应的存在下使阿拉伯糖供体和嘌呤源接触，由此将9-（β-D-阿拉伯呋喃糖基） - 嘌呤生产。

10. 发明授权

US4224409A Method for producing L-proline by fermentation 失效
标题翻译：通过发酵生产L-脯氨酸的方法
公开(公告)号：US4224409A
公开(公告)日：1980-09-23
申请号：US7782
申请日：1979-01-30
申请人： Shigeru Nakamori , Hajimu Morioka , Fumihiro Yoshinaga
发明人： Shigeru Nakamori , Hajimu Morioka , Fumihiro Yoshinaga
IPC分类号： C12P13/24 , C12R1/01 , C12R1/13 , C12R1/15
CPC分类号： C12P13/24
摘要： A method for producing L-proline by fermentation which comprises culturing an L-proline producing mutant in a culture medium until L-proline is accumulated in the culture medium, and recovering the accumulated L-proline; said mutant belonging to the genus Brevibacterium, Corynebacterium or Microbacterium and being resistant to DL-3,4-dehydroproline.
摘要翻译：一种通过发酵生产L-脯氨酸的方法，其包括在培养基中培养L-脯氨酸生产突变体直至在培养基中积累L-脯氨酸，并回收累积的L-脯氨酸; 所述突变体属于短杆菌属，棒状杆菌属或微杆菌属，并且对DL-3,4-脱氢脯氨酸具有抗性。

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