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1. 发明授权

US08709526B2 Use of a high-oleic and high-tocol diet in combination with a non-tocol antioxidant for improving animal meat quality 失效
标题翻译：使用高油酸和高蛋白饮食与非抗皱抗氧化剂联合，以改善动物肉质
公开(公告)号：US08709526B2
公开(公告)日：2014-04-29
申请号：US11530075
申请日：2006-09-08
申请人： Fred R. Wolf , Cindi S. Zimmermann , Court A. Saunders
发明人： Fred R. Wolf , Cindi S. Zimmermann , Court A. Saunders
IPC分类号： A23K1/00 , A23K1/18
CPC分类号： A23B4/20 , A23K20/158 , A23K20/174 , A23K50/10 , A23K50/30 , A23L3/3481 , A23L13/42 , A23L13/428 , A61K31/22 , A61K31/355
摘要： A novel method for improving the meat quality of an animal is provided. In one embodiment, the method comprises feeding the animal a diet supplemented with oleic acid and tocols and subsequently formulating the meat with a non-tocol antioxidant such as rosemary extract. The source of the oleic acid and/or tocols may be transgenic corn that employs the FAD-2 gene as a silencing agent for a high-oleic phenotype and/or expresses the HGGT gene for a high-tocotrienol phenotype. The method improves the quality of meat from both non-ruminants and ruminants.
摘要翻译：提供了一种改善动物肉质的新方法。在一个实施方案中，该方法包括向动物喂食补充有油酸和奶油的饮食，并随后用非蛋白抗氧化剂如迷迭香提取物配制肉。油酸和/或多酚的来源可以是使用FAD-2基因作为高油酸表型的沉默剂和/或表达高生育三烯酚表型的HGGT基因的转基因玉米。该方法提高了非反刍动物和反刍动物的肉质量。

2. 发明授权

US08563602B2 Method of improving animal tissue quality by supplementing the animal diet with oleic acid and selected tocols 失效
标题翻译：通过用油酸和选择的奶制品补充动物饮食来改善动物组织质量的方法
公开(公告)号：US08563602B2
公开(公告)日：2013-10-22
申请号：US13536226
申请日：2012-06-28
申请人： William D. Hitz , Thomas E. Sauber , Court Saunders , Fred R. Wolf
发明人： William D. Hitz , Thomas E. Sauber , Court Saunders , Fred R. Wolf
IPC分类号： A61K31/355 , A61P21/00
CPC分类号： A61K31/202 , A23K20/111 , A23K20/158 , A23K20/174 , A23K50/10 , A23K50/30 , A23K50/75
摘要： A novel method for improving the meat quality of an animal is provided. The method comprises feeding the animal a diet supplemented with oleic acid and selected tocols in amounts effective to improve the meat quality. The method may be practiced on non-ruminants and ruminants.
摘要翻译：提供了一种改善动物肉质的新方法。该方法包括以足以提高肉质的量给动物喂食补充有油酸的食物和选定的奶制品。该方法可以在非反刍动物和反刍动物上实施。

3. 发明申请

US20110070327A1 Use of High-Oleic Distillers Grains in Animal Feed to Improve Animal Product Quality 审中-公开
标题翻译：在动物饲料中使用高油源酒糟提高动物产品质量
公开(公告)号：US20110070327A1
公开(公告)日：2011-03-24
申请号：US12874298
申请日：2010-09-02
申请人： Fred R. Wolf , Fredric N. Owens , Cindi S. Zimmermann
发明人： Fred R. Wolf , Fredric N. Owens , Cindi S. Zimmermann
IPC分类号： A23K1/06 , A23K1/18
CPC分类号： A23K50/30 , A23K10/38 , A23K20/158 , A23K50/10 , A23K50/75 , Y02P60/873
摘要： A novel method for improving the meat, milk, and egg quality of livestock is provided. In one embodiment, the method comprises feeding the animal a diet supplemented with oleic acid and distillers grains. The source of the oleic acid may be distillers grain from high-oleic corn. The method improves the quality of meat from both non-ruminants and ruminants.
摘要翻译：提供了一种改善家畜肉，牛奶和鸡蛋质量的新方法。在一个实施方案中，该方法包括向动物喂食补充有油酸和酒糟的饮食。油酸的来源可能是来自高油酸玉米的酒糟。该方法提高了非反刍动物和反刍动物的肉质量。

4. 发明申请

US20080199565A1 Chewing Gum Containing Physiological Cooling Agents 审中-公开
标题翻译：含有生理冷却剂的口香糖
公开(公告)号：US20080199565A1
公开(公告)日：2008-08-21
申请号：US12111635
申请日：2008-04-29
申请人： Fred R. Wolf , Gordon N. McGrew , Jeffrey S. Hook , Lindell C. Richey , Mansukh M. Patel , Robert J. Yatka , David L. Witkewitz , Michael J. Greenberg , Henry T. Tyrpin , Kathryn T. Nelson
发明人： Fred R. Wolf , Gordon N. McGrew , Jeffrey S. Hook , Lindell C. Richey , Mansukh M. Patel , Robert J. Yatka , David L. Witkewitz , Michael J. Greenberg , Henry T. Tyrpin , Kathryn T. Nelson
IPC分类号： A23G4/06 , A23G4/20
CPC分类号： A23G4/06 , A23G4/062 , A23G4/068 , A23G4/20 , A23G2200/00
摘要： A method for producing a chewing gum, as well as the chewing gum so produced, incorporates a physiological cooling agent, such as acyclic carboxamide, or combinations of physiological cooling agents. In another embodiment a combination of physiological cooling agents is made in a modified release structure. The modified release/cooling agents combination is preferably obtained by physically modifying the properties of the combination of cooling agents by coating and drying. When incorporated into gum, these particles are adapted to enhance the shelf stability of the flavor and/or produce a modified release when the gum is chewed. In another embodiment, the physiological cooling agent is present with menthol and menthone.In another embodiment, coated chewing gum has a coating that comprises a physiological cooling agent. The preferred inventive chewing gum provides a high flavor impact in which the harsh notes normally associated with such a high flavor impact have been reduced or eliminated. In addition, the preferred inventive gum provides a clean, high-quality, cooling chewing gum coating with xylitol or other polyols where xylitol has been reduced in concentration or eliminated.
摘要翻译：用于生产口香糖的方法以及如此制备的口香糖包含生理冷却剂，例如无环羧酰胺，或生理冷却剂的组合。在另一个实施方案中，将生理冷却剂的组合制成改性释放结构。改性释放/冷却剂组合优选通过涂覆和干燥来物理改变冷却剂组合的性质来获得。当掺入胶中时，这些颗粒适于增强风味剂的贮存稳定性和/或当咀嚼口香糖时产生改性释放物。在另一个实施方案中，生理冷却剂存在薄荷醇和薄荷酮。在另一个实施方案中，涂覆的口香糖具有包含生理冷却剂的涂层。优选的本发明的口香糖提供高风味影响，其中通常与如此高的风味影响相关联的刺耳味通常已被减少或消除。此外，优选的本发明的胶提供了具有木糖醇或其它多元醇的清洁，高质量的冷却口香糖涂料，其中木糖醇已经被浓缩或被消除。

5. 发明授权

US6007849A Chewing gum containing meadowfoam oil 失效
标题翻译：口香糖含花草油
公开(公告)号：US6007849A
公开(公告)日：1999-12-28
申请号：US202542
申请日：1998-12-16
申请人： Fred R. Wolf
发明人： Fred R. Wolf
IPC分类号： A23G4/00 , A23G4/06 , A23G4/08 , A23G3/30
CPC分类号： A23G4/068 , A23G4/066 , A23G4/08
摘要： Improved chewing gum formulations and bases, as well as methods of producing chewing gum and bases are provided. The chewing gum includes meadowfoam seed oils from the plant genus Limnanthes. Meadowfoam seed oils can be used in the base and/or gum as a plasticizer. In an embodiment, meadowfoam oil is added to sucrose-type gum formulations replacing a small or large quantity of other fats, oils, and waxes. A variety of base and chewing gum formulations including meadowfoam oil can be created and/or utilized pursuant to the present invention.
摘要翻译： PCT No.PCT / US96 / 10638 Sec。 371日期1998年12月16日第 102（e）1998年12月16日PCT PCT 1996年6月20日PCT公布。 WO97 / 48285 PCT公开号日期1997年12月24日提供了改进的口香糖制剂和碱，以及生产口香糖和碱的方法。口香糖包括来自Limnanthes植物属的白兰地泡菜籽油。草莓泡沫籽油可以用作基础和/或树胶中的增塑剂。在一个实施方案中，将花粉发泡油加入到蔗糖型胶体制剂中，代替少量或大量的其它脂肪，油和蜡。根据本发明，可以产生和/或利用各种基础和口香糖制剂，包括花粉发泡油。

6. 发明授权

US5952019A Chewing gum containing gum talha 有权
标题翻译：口香糖含胶糖
公开(公告)号：US5952019A
公开(公告)日：1999-09-14
申请号：US142773
申请日：1998-11-18
申请人： Robert J. Yatka , Lindell C. Richey , Michael A. Reed , Jeffrey S. Hook , Fred R. Wolf
发明人： Robert J. Yatka , Lindell C. Richey , Michael A. Reed , Jeffrey S. Hook , Fred R. Wolf
IPC分类号： A23G4/00 , A23G4/08 , A23G4/10 , A23G3/30
CPC分类号： A23G4/10 , A23G4/08
摘要： Chewing gums containing gum talha and methods of making such gums are disclosed. In one embodiment, the gum comprises about 5% to about 95% gum base, about 0.1% to about 10% flavoring agent and gum talha, the gum talha being part of the bulking agent in the gum. The gum talha provides the gum with unique properties, and the gum is non-cariogenic. In another embodiments, the gum talha is codried with sweeteners or coevaporated with a plasticizing syrup to produce unique sweetening ingredients and syrups for gum. The gum talha may also be provided in the form of a rolling compound on the gum, or used with sugars or polyols to form a hard coating for a coated pellet gum.
摘要翻译： PCT No.PCT / US96 / 03508 Sec。 371日期：1998年11月18日 102（e）1998年11月18日日期PCT 1996年3月14日PCT公布。出版物WO97 / 33485 日期：1997年9月18日公开了含有牙龈的牙龈和制造这种牙龈的方法。在一个实施方案中，胶包含约5％至约95％的胶基，约0.1％至约10％的调味剂和胶树胶，胶质胶是牙龈中填充剂的一部分。牙龈胶提供独特的口香糖，口香糖是非致龋的。在另一个实施方案中，胶质糖与甜味剂共同化或与增塑糖浆共蒸发以产生独特的甜味成分和糖浆。胶质滑石也可以在口香糖上以滚动化合物的形式提供，或与糖或多元醇一起使用以形成用于涂覆的颗粒胶的硬涂层。

7. 发明授权

US5480805A Composition for modulating sterols in yeast 失效
标题翻译：用于调节酵母中的甾醇的组合物
公开(公告)号：US5480805A
公开(公告)日：1996-01-02
申请号：US240496
申请日：1994-05-10
申请人： Fred R. Wolf , Richard E. Cuellar
发明人： Fred R. Wolf , Richard E. Cuellar
IPC分类号： C12N9/90 , C12N15/61 , C12N1/19 , C12N15/81
CPC分类号： C12N9/90
摘要： A structural gene encoding a polypeptide with .DELTA.8-7 sterol isomerase activity is disclosed, Recombinant DNA molecules useful for transforming yeast and mutant yeast transformed with such recombinant DNA molecules are also disclosed. The structural gene is useful for modulating the accumulation of sterols in yeast comprising increasing the expression level of a structural gene encoding a polypeptide having .DELTA.8-7 sterol isomerase activity in a mutant yeast having single or double defects in the expression of sterol biosynthetic enzymes is provided.
摘要翻译：公开了编码具有DELTA 8-7甾醇异构酶活性的多肽的结构基因，用于转化酵母的重组DNA分子和用这种重组DNA分子转化的突变酵母。结构基因可用于调节酵母中甾醇的积累，包括在具有单或双缺陷的甾醇生物合成酶表达的突变体酵母中增加编码具有DELTA 8-7甾醇异构酶活性的多肽的结构基因的表达水平为提供。

8. 发明授权

US5365017A Method and composition for increasing sterol accumulation in higher plants 失效
公开(公告)号：US5365017A
公开(公告)日：1994-11-15
申请号：US119263
申请日：1993-09-09
申请人： Joseph Chappell , Court A. Saunders , Fred R. Wolf , Richard E. Cuellar
发明人： Joseph Chappell , Court A. Saunders , Fred R. Wolf , Richard E. Cuellar
IPC分类号： A01H5/00 , C12N5/10 , C12N9/04 , C12N15/09 , C12N15/53 , C12N15/82 , C12P33/00 , A01H1/04 , C12N15/00 , C12N9/02 , C07H21/04
CPC分类号： C12N9/0006 , C12N15/8243 , C12N15/8286
摘要： A method of increasing sterol accumulation in a plant by increasing the copy number of a gene encoding a polypeptide having HMG-CoA reductase activity is disclosed. The copy number is preferably increased by transforming plants with a recombinant DNA molecule comprising a vector operatively linked to an exogenous DNA segment that encodes a polypeptide having HMG-CoA reductase activity, and a promoter suitable for driving the expression of said polypeptide. Also disclosed are a method of increasing cycloartenol accumulation in a plant, a method of increasing the resistance of plants to pests and the transformed plants themselves.

9. 发明授权

US5153269A Thermoplastic elastomer blends of a polyvinyl chloride-acrylate copolymer and a cured acrylate elastomer 失效
标题翻译：聚氯乙烯 - 丙烯酸酯共聚物和固化的丙烯酸酯弹性体的热塑性弹性体共混物
公开(公告)号：US5153269A
公开(公告)日：1992-10-06
申请号：US620677
申请日：1990-12-03
申请人： William S. Greenlee , Josef C. Vyvoda , Fred R. Wolf
发明人： William S. Greenlee , Josef C. Vyvoda , Fred R. Wolf
IPC分类号： C08L27/06 , C08L33/08
CPC分类号： C08L27/06 , C08L33/08
摘要： Thermoplastic elastomer blends containing polyvinyl chloride having improved oil resistance, exceptionally low compression set and softness are made by mixing a polyvinyl chloride-acrylate copolymer with effective amounts of cured acrylate elastomers. The polyvinyl chloride-acrylate copolymer has an inherent viscosity of from about 0.3 to about 4.0 and is made from a vinyl constituent which is a vinyl chloride monomer with an optional vinyl component comonomer and one or more acrylate monomers having the formula ##STR1## wherein R.sup.1 is an aliphatic, an aromatic, or combinations thereof, having from 1 to 18 carbon atoms, or a halogen derivative thereof, or hydrogen, and R.sup.2 is an aliphatic, an aromatic, an alkyl hydroxyl, or combinations thereof, having from 1 to 18 carbon atoms, or a halogen derivative thereof; or a hydrocarbyl ether such as an alkoxyalkyl, a phenoxyaryl, a phenoxyalkyl, or combinations thereof, having from 2 to 1,000 carbon atoms, or a substituted halogen, oxygen, sulfur, or nitrogen derivative thereof, and wherein the acrylate elastomer is made from one or more acrylate monomers having the formula ##STR2## wherein R.sup.3 is an aliphatic, an aromatic, or combinations thereof, having from 1 to 18 carbon atoms, or a halogen derivative thereof, or hydrogen, and R.sup.4 is an aliphatic, an aromatic, an alkyl hydroxyl, or combinations thereof, having from 1 to 18 carbon atoms, or a halogen derivative thereof; or a hydrocarbyl ether such as an alkoxyalkyl, a phenoxyaryl, a phenoxyalkyl, or combinations thereof having from 2 to 1,000 carbon atoms, or a substituted halogen, oxygen, sulfur, or nitrogen derivative thereof.
摘要翻译：通过将聚氯乙烯 - 丙烯酸酯共聚物与有效量的固化的丙烯酸酯弹性体混合，制备含有改善的耐油性，特别低的压缩永久变形和柔软度的聚氯乙烯的热塑性弹性体共混物。聚氯乙烯 - 丙烯酸酯共聚物的特性粘度为约0.3至约4.0，并且由乙烯基成分制成，该乙烯基成分是具有任选的乙烯基成分共聚单体的氯乙烯单体和一种或多种具有式I的丙烯酸酯单体其中R 1是具有1至18个碳原子的脂族，芳族或其组合，或其卤素衍生物或氢，并且R 2是脂族，芳族，烷基羟基或其组合，其具有1 至18个碳原子，或其卤素衍生物; 或具有2至1,000个碳原子的烃基醚如烷氧基烷基，苯氧基芳基，苯氧基烷基或其组合，或其取代的卤素，氧，硫或氮衍生物，其中丙烯酸酯弹性体由一种或更多具有式II的丙烯酸酯单体，其中R 3是具有1至18个碳原子的脂族，芳族或其组合，或其卤素衍生物或氢，并且R 4是脂族，芳族，具有1至18个碳原子的烷基羟基或其组合，或其卤素衍生物; 或具有2至1,000个碳原子的烃基醚如烷氧基烷基，苯氧基芳基，苯氧基烷基或其组合，或其取代的卤素，氧，硫或氮衍生物。

10. 发明授权

US5589619A Process and composition for increasing squalene and sterol accumulation in higher plants 失效
标题翻译：在高等植物中增加角鲨烯和甾醇积累的方法和组合物
公开(公告)号：US5589619A
公开(公告)日：1996-12-31
申请号：US308551
申请日：1994-12-08
申请人： Joseph Chappell , Court A. Saunders , Fred R. Wolf
发明人： Joseph Chappell , Court A. Saunders , Fred R. Wolf
IPC分类号： A01H5/00 , C12N5/10 , C12N9/04 , C12N15/09 , C12N15/53 , C12N15/82 , C12P33/00 , C12N15/00
CPC分类号： C12N9/0006 , C12N15/8243 , C12N15/8286
摘要： A process of increasing squalene and sterol accumulation in a transgenic plant by increasing the amount of a gene encoding a polypeptide having HMG-CoA reductase activity is disclosed. The amount is preferably increased by transforming plant cells with a recombinant DNA molecule comprising a vector operatively linked to an exogenous DNA segment that encodes a polypeptide having HMG-CoA reductase activity, and a promoter suitable for driving the expression of said polypeptide to form a transformed plant cell and regenerating a transgenic plant from that transformed cell. Also disclosed are a process of increasing pest resistance in a transgenic plant, transgenic plants and transgenic seeds capable of germinating into transgenic plants.
摘要翻译：公开了通过增加编码具有HMG-CoA还原酶活性的多肽的基因的量来增加转基因植物中角鲨烯和甾醇积累的方法。优选通过用包含可操作地连接到编码具有HMG-CoA还原酶活性的多肽的外源DNA区段的载体的重组DNA分子和适于驱动所述多肽的表达以形成转化的载体的启动子来转化植物细胞来增加量植物细胞并从转化细胞再生转基因植物。还公开了在转基因植物，转基因植物和能够发芽转化植物的转基因种子中增加害虫抗性的方法。

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