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1. 发明授权

US09676914B2 Process for producing polymer foams 有权
公开(公告)号：US09676914B2
公开(公告)日：2017-06-13
申请号：US14651764
申请日：2013-12-23
申请人： Fondazione Istituto Italiano de Tecnologia
发明人： Despina Fragouli , Elisa Mele , Athanasia Athanasiou
IPC分类号： C08J9/26 , C08J9/36 , C08J9/00 , A61L27/48 , A61L27/56
CPC分类号： C08J9/26 , A61L27/48 , A61L27/56 , A61L2400/08 , C08J9/0061 , C08J9/36 , C08J2201/046 , C08J2201/0464 , C08J2205/022 , C08J2205/05 , C08J2333/06 , C08J2375/04 , C08J2383/04 , C08J2389/00 , C08J2400/14 , C08J2401/02 , C08J2405/04 , C08J2405/08 , C08J2431/04 , C08J2433/26 , C08J2477/06
摘要： Process for the production of a polymer foam with use of hydrogel pearls as porosity generating template, comprising the steps of:—providing a matrix of polymer or prepolymer in viscous state including, as a dispersed phase, hydrogel pearls, where said pearls are dispersed in said matrix so as to generate intercommunicating cells,—causing the solidification of the matrix of polymer or prepolymer to obtain said polymer foam including said hydrogel pearls, characterised in that it comprises the operation of subjecting the thus obtained foam to conditions which cause the dehydration of said hydrogel pearls so as to obtain a reduction of volume of said pearls and—removing the dehydrated pearls by immersion in water of the polymer foam or by exposure of the foam to a flow of pressurized gas or water.

2. 发明申请

US20190177313A1 PIPERZINYL METHANONE NAAA INHIBITORS 审中-公开
公开(公告)号：US20190177313A1
公开(公告)日：2019-06-13
申请号：US16301200
申请日：2017-05-16
申请人： The Regents of the University of California , Fondazione Istituto Italiano De Tecnologia
发明人： Daniele Piomelli , Rita Scarpelli , Marco Migliore
IPC分类号： C07D417/04 , A61P25/28 , A61P25/16 , C07D413/04 , C07D417/14
摘要： Disclosed herein, inter alia, are compositions and methods for modulating the activity of N-acylethanolamine acid amidase for the treatment of a pathological state, including pain, an inflammatory condition, or a neurodegenerative disorder.

3. 发明申请

US20160039117A1 Method for Producing Shaped Polymeric Microparticles 审中-公开
标题翻译：生产聚合物微粒的方法
公开(公告)号：US20160039117A1
公开(公告)日：2016-02-11
申请号：US14782459
申请日：2014-04-08
申请人： Fondazione Istituto Italiano de Tecnologia
发明人： Raffaele Vecchione , Renato De Alteriis , Paolo Antonio Netti
IPC分类号： B29B9/12
CPC分类号： B29B9/12 , B29B9/16 , B29B2009/125 , B29B2009/166 , B29K2067/04
摘要： Method for producing shaped polymeric microparticles of non-spherical shape, comprising the steps of: placing one or more microparticles of substantially spherical shape in a respective micro-cavity of a mould having the desired non-spherical shape; subjecting said microparticles to softening by exposure to a solvent or mixture of solvent/non-solvent, in the liquid or vapour state, adapted to plasticize the polymeric material constituting said microparticles, and possibly assisting the solvent plasticization process by heat treatment, not excluding the possibility, in less critical cases in terms of conservation of the microstructure, of carrying out heat treatment exclusively, at a temperature not exceeding 40% of the glass transition temperature of the polymer material; and removing said microparticles from the mould cavities.
摘要翻译：一种制造非球形的成型聚合物微粒的方法，包括以下步骤：将一个或多个基本上为球形的微粒放置在具有所需非球形的模具的相应微腔中; 通过暴露于液体或蒸汽状态的溶剂或非溶剂的溶剂或混合物来使所述微粒软化，其适于塑化构成所述微粒的聚合物材料，并且可能通过热处理辅助溶剂增塑过程，不排除在不超过聚合物材料的玻璃化转变温度的40％的温度的情况下，在微观结构保存的不太关键的情况下，专门进行热处理的可能性; 并从模腔中除去所述微粒。

4. 发明申请

US20150315353A1 Process for Producing Polymer Foams 有权
标题翻译：生产聚合物泡沫的方法
公开(公告)号：US20150315353A1
公开(公告)日：2015-11-05
申请号：US14651764
申请日：2013-12-23
申请人： FONDAZIONE ISTITUTO ITALIANO DE TECNOLOGIA
发明人： Despina Fragouli , Elisa Mele , Athanasia Athanasiou
IPC分类号： C08J9/26 , C08J9/36 , C08J9/00
CPC分类号： C08J9/26 , A61L27/48 , A61L27/56 , A61L2400/08 , C08J9/0061 , C08J9/36 , C08J2201/046 , C08J2201/0464 , C08J2205/022 , C08J2205/05 , C08J2333/06 , C08J2375/04 , C08J2383/04 , C08J2389/00 , C08J2400/14 , C08J2401/02 , C08J2405/04 , C08J2405/08 , C08J2431/04 , C08J2433/26 , C08J2477/06
摘要： Process for the production of a polymer foam with use of hydrogel pearls as porosity generating template, comprising the steps of:—providing a matrix of polymer or prepolymer in viscous state including, as a dispersed phase, hydrogel pearls, where said pearls are dispersed in said matrix so as to generate intercommunicating cells,—causing the solidification of the matrix of polymer or prepolymer to obtain said polymer foam including said hydrogel pearls, characterised in that it comprises the operation of subjecting the thus obtained foam to conditions which cause the dehydration of said hydrogel pearls so as to obtain a reduction of volume of said pearls and—removing the dehydrated pearls by immersion in water of the polymer foam or by exposure of the foam to a flow of pressurized gas or water.
摘要翻译：使用水凝胶珍珠作为孔隙率产生模板生产聚合物泡沫体的方法，包括以下步骤：提供粘性状态的聚合物或预聚物基质，包括作为分散相的水凝胶珍珠，其中所述珍珠分散在所述基质以产生相互连通的细胞， - 使聚合物或预聚物基质凝固得到包括所述水凝胶珍珠的所述聚合物泡沫体，其特征在于，其包括将由此获得的泡沫体经受使引起脱水的条件的操作所述水凝胶珍珠，以便通过浸入聚合物泡沫的水中或通过将泡沫暴露于加压气体或水的流动来获得所述珍珠的体积减少和脱水珍珠的去除。

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