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    • 2. 发明申请
    • PRODUCTION AND USE OF REGULATORY T CELLS
    • 生产和使用调节性T细胞
    • WO2007125362A1
    • 2007-11-08
    • PCT/GB2007/050210
    • 2007-04-24
    • ISIS INNOVATION LTDFENG, GangWOOD, Kathryn, JayneBUSHELL, Andrew, Richard
    • FENG, GangWOOD, Kathryn, JayneBUSHELL, Andrew, Richard
    • C12N5/06
    • C12N5/0636
    • An ex vivo method for generating a population of Treg capable of suppressing rejection of an organ or tissue transplant from a donor animal in a recipient animal, comprises culturing CD4 + T cells from the recipient animal in the presence of IFN-γ plus either donor specific or third-party antigen presenting cells, and harvesting a population of Treg capable of suppressing rejection in the recipient animal. The Treg can be administered, for example intravenously to the recipient, preferably immediately prior to the transplant to suppress transplant rejection. A similar strategy applicable to generating a population of Treg capable of suppressing an autoimmune condition in an animal wherein the animal mounts an immune reaction against an autoantigen, comprises culturing CD4 + T cells from the animal in the presence of cells presenting the autoantigen and IFN-γ and harvesting a population of autoantigen reactive Treg.
    • 用于产生能够抑制受体动物中供体动物的器官或组织移植排斥反应的Treg群体的离体方法包括:在受体动物的存在下培养CD4 + T细胞, IFN-α 加上供体特异性或第三方抗原呈递细胞,以及收获能抑制受体动物排斥反应的Treg群体。 Treg可以例如静脉内施用于接受者,优选在移植前,以抑制移植排斥。 适用于产生能够抑制动物中自身免疫状态的Treg群体的类似策略,其中动物对抗自身抗原产生免疫反应,包括在动物的存在下培养CD4 + T细胞, 呈现自身抗原和IFN- 并收获自身抗原反应性Treg群体。
    • 6. 发明授权
    • Cap assembly with desirable safety performance
    • 盖组件具有理想的安全性能
    • US08409736B2
    • 2013-04-02
    • US12819403
    • 2010-06-21
    • Peng WangFeng-gang ZhaoWei Chen
    • Peng WangFeng-gang ZhaoWei Chen
    • H01M2/12
    • H01M2/0408H01M2/1241H01M10/425H01M2200/103
    • A cap assembly with desirable safety performance for use in lithium ion batteries, includes an insulating gasket defining a through hole therein, a rupture plate positioned in the through hole, a vent plate defining an air hole electrically connected with the rupture plate, a current interrupt device disposed on the rupture plate, and an end cap defining an air exhaust hole assembled on the current interrupt device. The current interrupt device has an upper conductive plate electrically connected with the end cap, a lower conductive plate electrically connected with the rupture plate, and a fuse electrically connecting the upper conductive plate and the lower conductive plate. When the current intensity in the lithium ion battery exceeds a predetermined value, the fuse melts to cut off the current path.
    • 具有用于锂离子电池的理想安全性能的盖组件包括在其中限定通孔的绝缘衬垫,位于通孔中的断裂板,限定与断裂板电连接的气孔的通气板,电流中断 设置在破裂板上的装置和限定在当前中断装置上组装的排气孔的端盖。 电流中断装置具有与端盖电连接的上导电板,与断裂板电连接的下导电板,以及将上导电板和下导电板电连接的保险丝。 当锂离子电池中的电流强度超过预定值时,熔断熔断电流路径。
    • 8. 发明申请
    • CAP ASSEMBLY WITH DESIRABLE SAFETY PERFORMANCE
    • 具有安全性能的CAP大会
    • US20100330402A1
    • 2010-12-30
    • US12819403
    • 2010-06-21
    • Peng WangFeng-gang ZhaoWei Chen
    • Peng WangFeng-gang ZhaoWei Chen
    • H01M2/12
    • H01M2/0408H01M2/1241H01M10/425H01M2200/103
    • A cap assembly with desirable safety performance for use in lithium ion batteries, includes an insulating gasket defining a through hole therein, a rupture plate positioned in the through hole, a vent plate defining an air hole electrically connected with the rupture plate, a current interrupt device disposed on the rupture plate, and an end cap defining an air exhaust hole assembled on the current interrupt device. The current interrupt device has an upper conductive plate electrically connected with the end cap, a lower conductive plate electrically connected with the rupture plate, and a fuse electrically connecting the upper conductive plate and the lower conductive plate. When the current intensity in the lithium ion battery exceeds a predetermined value, the fuse melts to cut off the current path.
    • 具有用于锂离子电池的理想安全性能的盖组件包括在其中限定通孔的绝缘衬垫,位于通孔中的断裂板,限定与断裂板电连接的气孔的通气板,电流中断 设置在破裂板上的装置和限定在当前中断装置上组装的排气孔的端盖。 电流中断装置具有与端盖电连接的上导电板,与断裂板电连接的下导电板,以及将上导电板和下导电板电连接的保险丝。 当锂离子电池中的电流强度超过预定值时,熔断熔断电流路径。
    • 10. 发明申请
    • RELIABILITY PROCESSING METHODS AND SYSTEMS IN THE NETWORKING OF METRO ETHERNET NETWORK PROVIDING MULTI-SERVICE
    • 网络提供多业务网络的可靠性处理方法与系统
    • US20090290591A1
    • 2009-11-26
    • US12536030
    • 2009-08-05
    • Xuejiang ZHANGGuangyu SUNFeng GANGMing WEIXindong TENGHongsen MAOShudong WANG
    • Xuejiang ZHANGGuangyu SUNFeng GANGMing WEIXindong TENGHongsen MAOShudong WANG
    • H04L12/56
    • H04L45/00H04L45/28H04L45/586
    • A reliability processing method and system in networking of Metro Ethernet Network providing multi-service are provided. The method includes: establishing a Virtual Router Redundancy Protocol (VRRP) group with at least two service control gateways, establishing network connections between an access device (UPE) and the service control gateways in the Virtual Router Redundancy Protocol group by a Virtual Private LAN Service (VPLS); establishing Layer 2 service and Layer 3 service connections between an active service control gateway and the Access device after active and standby service control gateways in the Virtual Router Redundancy Protocol group are determined according to a processing result of a Virtual Router Redundancy Protocol message, and performing Layer 2 service and Layer 3 service processing. With the present invention, when the MAN service is in fault, all the Layer 2 and Layer 3 services may be switched to the standby service control gateway quickly, and the switching may be on the order of milliseconds. Therefore, the reliability of the Layer 2 and Layer 3 services of the MAN may be sufficiently guaranteed, and the overhead of the system may be reduced significantly.
    • 提供了提供多业务的城域以太网网络的可靠性处理方法和系统。 该方法包括:通过至少两个服务控制网关建立虚拟路由冗余协议(VRRP)组,通过虚拟专用局域网服务在虚拟路由器冗余协议组中建立接入设备(UPE)与业务控制网关之间的网络连接 (VPLS); 根据虚拟路由器冗余协议消息的处理结果确定虚拟路由器冗余协议组中的主备服务控制网关之后,在活动业务控制网关与接入设备之间建立二层业务和三层业务连接,并执行 二层业务和三层业务处理。 根据本发明,当MAN业务处于故障状态时,所有二层和三层业务都可以快速切换到备用业务控制网关,并且交换可能在几毫秒左右。 因此,可以充分保证城域网二层和三层业务的可靠性,同时可以显着降低系统开销。