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    • 5. 发明申请
    • DETECTION OF MECHANICAL STRESS ON COATED ARTICLES
    • 检测涂层制品的机械应力
    • WO2012125736A2
    • 2012-09-20
    • PCT/US2012/029089
    • 2012-03-14
    • SIO2 MEDICAL PRODUCTS, INC.FISK, Thomas E.
    • FISK, Thomas E.
    • A61M5/31
    • G01L1/24A61M5/3129A61M5/347A61M5/5086A61M2005/3104A61M2205/0294A61M2205/6081
    • A medical device comprising a wall, a coating of SiO x , and a piezochromic material is disclosed. The piezochromic material is associated with the wall, and changes its appearance when the wall is exposed to mechanical stress exceeding a threshold intensity. Also disclosed is a method of interrogating a closed medical device for processing damage, comprising at least the acts of providing a closed medical device and inspecting the medical device. The medical device is inspected from the exterior for a change in the appearance of at least some of its piezochromic material that is characteristic of exposure of the wall to mechanical stress exceeding a threshold intensity greater than zero. Optionally in any embodiment inspecting is carried out using a spectrophotometer to determine the change in the color of at least some of its piezochromic material.
    • 公开了包括壁,SiOx涂层和压敏变色材料的医疗装置。 压电变色材料与壁相关联,并且当壁暴露于超过阈值强度的机械应力时改变其外观。 还公开了询问用于处理损伤的封闭式医疗装置的方法,至少包括提供封闭的医疗装置和检查医疗装置的动作。 医疗设备从外部检查其至少一些其压电色素材料的外观变化,其特征在于壁的机械应力超过超过零的阈值强度。 可选地,在任何实施例中,使用分光光度计进行检查以确定其压电色素材料的至少一些的颜色变化。
    • 7. 发明申请
    • VESSEL PROCESSING
    • 船舶加工
    • WO2010132579A3
    • 2011-03-31
    • PCT/US2010034568
    • 2010-05-12
    • CV HOLDINGS LLCFISK THOMAS EFELTS JOHN TABRAMS ROBERT S
    • FISK THOMAS EFELTS JOHN TABRAMS ROBERT S
    • C23C16/44A61J1/05C23C16/04C23C16/50C23C16/54
    • C23C16/54A61M5/3129A61M2005/3131C23C16/045C23C16/503C23C16/52G01M3/26G01N21/9072G01N21/9081
    • A vessel processing system for coating of a vessel is provided, the system comprising: a first processing station configured for performing a first processing of an interior surface of the vessel, a second processing station spaced from the first processing station and configured for performing a second processing of the interior surface of the vessel, a vessel holder comprising a vessel port configured to receive and seat an opening of the vessel for processing the interior surface of the seated vessel via the vessel port at the first processing station and at the second processing station, and a conveyor arrangement for transporting the vessel holder and the seated vessel after the first processing from the first processing station to the second processing station for the second processing of the interior surface of the seated vessel at the second processing station.
    • 提供了一种用于涂覆容器的容器处理系统,该系统包括:第一处理站,被配置为执行容器的内表面的第一处理;第二处理站,与第一处理站间隔开并且被配置为执行第二处理站 处理容器的内表面的容器保持器,容器保持器包括容器端口,该容器端口构造成容纳和安置容器的开口,用于经由第一处理站处的容器端口和第二处理站处理就座容器的内表面 以及传送装置,用于在第一处理站之后将容器保持器和就座容器从第一处理站传送到第二处理站,用于在第二处理站处对就座容器的内表面进行第二次处理。
    • 9. 发明申请
    • HALOGENATED OR PARYLENE POLYMER COATING
    • 聚合或聚合物涂料
    • WO2014052792A1
    • 2014-04-03
    • PCT/US2013/062247
    • 2013-09-27
    • SIO2 MEDICAL PRODUCTS, INC.RESNICK, Paul R.FISK, Thomas E.WEIKART, Christopher
    • RESNICK, Paul R.FISK, Thomas E.WEIKART, Christopher
    • C23C14/16C08F2/46
    • A61M5/31513A61J1/06A61M2005/3131A61M2207/00A61M2207/10C23C16/045C23C16/401
    • A container, for example a syringe, cartridge, vial or similar article including a barrel or other vessel and a stopper, O-ring, plunger tip or piston. The vessel substrate defines a lumen and an internal sliding surface on the vessel substrate adjacent to the lumen. The stopper, O-ring, plunger tip or piston has an external sliding surface slidable in the lumen at least substantially in contact with the internal sliding surface. The internal sliding surface, the external sliding surface, or both are made at least in part of a parylene or halogenated polymer, which can be in the form of a coating or a bulk material. Methods of making the syringe, cartridge, or similar article using chemical vapor deposition, as by depositing the parylene or halogenated polymer directly or with intervening layers to define the external sliding surface, the internal internal sliding surface, or both are disclosed.
    • 容器,例如注射器,药筒,小瓶或类似物品,其包括镜筒或其他容器和塞子,O形环,柱塞尖端或活塞。 容器衬底限定了与腔相邻的容器衬底上的管腔和内部滑动表面。 止动器O形环,柱塞尖端或活塞具有可在内腔中滑动至少基本上与内部滑动表面接触的外部滑动表面。 内部滑动表面,外部滑动表面或两者均至少部分由聚对二甲苯或卤化聚合物制成,其可以是涂层或散装材料的形式。 公开了通过使用化学气相沉积来制造注射器,药筒或类似物品的方法,如通过直接或间接沉积聚对二甲苯或卤化聚合物以限定外部滑动表面,内部内部滑动表面或两者。