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1. 发明申请

WO2009029416A1 CONFINING/FOCUSING VORTEX FLOW TRANSMISSION STRUCTURE, MASS SPECTROMETRY SYSTEMS, AND METHODS OF TRANSMITTING PARTICLES, DROPLETS, AND IONS 审中-公开
标题翻译：配置/聚焦VORTEX流量传输结构，质谱系统以及发送颗粒，滴液和离子的方法
公开(公告)号：WO2009029416A1
公开(公告)日：2009-03-05
申请号：PCT/US2008/073005
申请日：2008-08-13
申请人： GEORGIA TECH RESEARCH CORPORATION , FEDOROV, Andrei, G.
发明人： FEDOROV, Andrei, G.
IPC分类号： G01N33/53 , B01D59/00
CPC分类号： H01J49/066 , Y10T137/2087 , Y10T137/2098 , Y10T137/2109
摘要： Briefly described, embodiments of the present disclosure include: confining/focusing vortex flow transmission structures, mass spectrometry systems including a confining/focusing vortex flow transmission structure, methods of using the confining/focusing vortex flow transmission structure, methods of using mass spectrometry system, methods of transmitting droplets and ions, methods of evaporating droplets and desolvating ions, and the like.
摘要翻译：简要描述，本公开的实施例包括：限制/聚焦涡流传输结构，包括限制/聚焦涡流传输结构的质谱系统，使用约束/聚焦涡流传输结构的方法，使用质谱系统的方法，透射液滴和离子的方法，蒸发液滴和脱溶剂的方法等。

2. 发明申请

WO2008147404A1 SYNTHESIS AND BIOLOGICAL ACTIVITY OF PHOTOPOLYMERIZABLE DERIVATIVES OF GLYPHOSATE 审中-公开
标题翻译：谷氨酸光合可衍生衍生物的合成和生物活性
公开(公告)号：WO2008147404A1
公开(公告)日：2008-12-04
申请号：PCT/US2007/026231
申请日：2007-12-21
申请人： BOWLING GREEN STATE UNIVERSITY , NECKERS, Douglas, C. , BOGDANOVA, Aneta , FEDOROV, Andrei, V.
发明人： NECKERS, Douglas, C. , BOGDANOVA, Aneta , FEDOROV, Andrei, V.
IPC分类号： A01N25/00
CPC分类号： A01N57/20
摘要： The present invention holds forth improvements in the field of herbicide synthesis, their application, and methods of plant and weed control and antifouling. The present invention includes the synthesis of new acrylate and methacrylate derivatives of a glyphosate. Two isomers resulting from a hindered rotation around the amide CN bond are observed for both acrylic and methacrylic analogs and barriers for internal rotation are obtained. Biological activity tests indicate that functionalized glyphosates possess herbicidal activity similar to the parent compound.
摘要翻译：本发明在除草剂合成领域，它们的应用以及植物和杂草控制和防污方法方面进行了改进。本发明包括合成草甘膦的新的丙烯酸酯和甲基丙烯酸酯衍生物。对于丙烯酸和甲基丙烯酸类似物都观察到由酰胺CN键周围的受阻旋转产生的两种异构体，并且获得了用于内部旋转的屏障。生物活性试验表明，官能化草甘膦具有类似于母体化合物的除草活性。

3. 发明申请

WO2005065072A2 ELECTROSPRAY SYSTEMS AND METHODS 审中-公开
标题翻译：电喷雾系统和方法
公开(公告)号：WO2005065072A2
公开(公告)日：2005-07-21
申请号：PCT/US2004/028482
申请日：2004-09-01
申请人： GEORGIA TECH RESEARCH CORPORATION , FEDOROV, Andrei, G. , DEGERTEKIN, F. Levent
发明人： FEDOROV, Andrei, G. , DEGERTEKIN, F. Levent
IPC分类号： B01D59/44 , B01L3/02 , H01J49/00 , H01J49/04 , H01J49/10 , H01L21/302 , H01L21/461
CPC分类号： B05B17/0638 , B01L3/0268 , B01L2400/0439 , B05B5/025 , F23D11/32 , H01J49/0018 , H01J49/165
摘要： Electrospray systems, electrospray structures, removable electrospray structures, methods of operating electrospray systems, and methods of fabricating electrospray systems, are disclosed.
摘要翻译：公开了电喷雾系统，电喷雾结构，可移除电喷雾结构，操作电喷雾系统的方法以及制造电喷雾系统的方法。

4. 发明申请

WO2009145828A2 TWO SLOW-STEP POLYMERASE ENZYME SYSTEMS AND METHODS 审中-公开
标题翻译：两个慢步聚合酶酶系统和方法
公开(公告)号：WO2009145828A2
公开(公告)日：2009-12-03
申请号：PCT/US2009002003
申请日：2009-03-30
申请人： PACIFIC BIOSCIENCES CALIFORNIA , BJORNSON KEITH , LEE HAROLD , KORLACH JONAS , TURNER STEPHEN , BIBILLO AREK , CHRISTIANS FRED , EMIG ROBIN , HE MOLLY , PARK INSIL , JIA LEI , FEDOROV ANDREI , LYLE JOHN
发明人： BJORNSON KEITH , LEE HAROLD , KORLACH JONAS , TURNER STEPHEN , BIBILLO AREK , CHRISTIANS FRED , EMIG ROBIN , HE MOLLY , PARK INSIL , JIA LEI , FEDOROV ANDREI , LYLE JOHN
IPC分类号： C12Q1/68 , C12N9/12 , C12Q1/48
CPC分类号： C12Q1/6869 , C12Q1/6874 , C12Q2527/125 , C12Q2527/119 , C12Q2527/101 , C12Q2565/1015 , C12Q2527/137 , C12Q2521/101
摘要： Compositions, kits, methods and systems for nucleotide sequencing comprising producing polymerase reactions that exhibit two kinetically observable steps within an observable phase of the polymerase reaction. Two slow step systems can be produced, for example, by selecting the appropriate polymerase enzyme, polymerase reaction conditions including cofactors, and polymerase reaction substrates including the primed template and nucleotides.
摘要翻译：用于核苷酸测序的组合物，试剂盒，方法和系统，其包括产生聚合酶反应，其在聚合酶反应的可观察期内显示两个动力学可观察步骤。可以通过例如选择合适的聚合酶，包括辅因子的聚合酶反应条件和包括引发的模板和核苷酸的聚合酶反应底物来产生两个缓慢的步骤系统。

5. 发明申请

WO2007126500A1 REMOTE CURING OF POLYMER COATING BY GASEOUS, VAPOROUS OR AEROSOL INITIATING AGENT 审中-公开
标题翻译：由气体，蒸气或航空发动剂远程固化聚合物涂层
公开(公告)号：WO2007126500A1
公开(公告)日：2007-11-08
申请号：PCT/US2007/004840
申请日：2007-02-23
申请人： BOWLING GREEN STATE UNIVERSITY , NECKERS, Douglas, C. , FEDOROV, Andrei, V. , ERMOSHKIN, Andrey, A.
发明人： NECKERS, Douglas, C. , FEDOROV, Andrei, V. , ERMOSHKIN, Andrey, A.
IPC分类号： C04B16/00 , C04B7/00 , C08L93/00
CPC分类号： B05D3/046 , B05D1/60
摘要： The present invention is a method and apparatus for remote curing of resin- coated surfaces and articles by means of a vaporous curing agent. The method of the present invention includes the steps: (a) providing a surface of the substrate with a layer of a coating precursor comprising a curable material and a stabilized curing agent that is adapted to react with a gaseous, vaporous or aerosol initiating agent to activate the stabilized curing agent so as to cause the curable material to undergo a curing reaction; (b) subjecting the coating precursor to the gaseous, vaporous or aerosol initiating agent for sufficient time to initiate the curing reaction, and allowing the coating precursor to form a cured coating on the substrate. Another variation of the method of the present invention involves the reversal of the positions of the active compounds utilizing the interaction between the gaseous, vaporous or aerosol curing agent and coating precursor comprising a curable material and initiating agent.
摘要翻译：本发明是通过蒸发固化剂远程固化树脂涂层表面和制品的方法和装置。本发明的方法包括以下步骤：（a）为基材的表面提供包含可固化材料和稳定的固化剂的涂层前体层，其适于与气态，气态或气溶胶引发剂反应，激活稳定的固化剂，使可固化材料发生固化反应; （b）使涂料前体经历气态，气态或气溶胶引发剂足够的时间以引发固化反应，并使涂料前体在基材上形成固化的涂层。本发明方法的另一个变化是使用气态，气相或气溶胶固化剂与包含可固化材料和引发剂的涂层前体之间的相互作用来反转活性化合物的位置。

6. 发明申请

WO2012021733A3 PHOTODAMAGE MITIGATION COMPOUNDS AND SYSTEMS 审中-公开
标题翻译：光化学减轻化合物和体系
公开(公告)号：WO2012021733A3
公开(公告)日：2012-08-02
申请号：PCT/US2011047468
申请日：2011-08-11
申请人： PACIFIC BIOSCIENCES CALIFORNIA , YUE STEPHEN , WEBER ROBERT , KONG XIANGXU , FEDOROV ANDREI , LYLE JOHN
发明人： YUE STEPHEN , WEBER ROBERT , KONG XIANGXU , FEDOROV ANDREI , LYLE JOHN
IPC分类号： G01N33/52 , C12Q1/25 , C12Q1/68
CPC分类号： C12Q1/6869 , C12N13/00 , C12Q1/25 , G01N33/52 , G01N33/54373 , G01N2333/91245 , G01N2333/916
摘要： Compositions, devices, systems and methods for reducing and/or preventing photo-induced damage of one or more reactants in an illuminated analytical reaction by addition of one or more photoprotective compounds to the reaction mixture and allowing the reaction to proceed for a period that is less than a photo-induced damage threshold period.
摘要翻译：用于通过向反应混合物中加入一种或多种光保护性化合物并允许反应进行一段时间，以减少和/或防止照明分析反应中的一种或多种反应物的光诱导损伤的组合物，装置，系统和方法小于光致伤害阈值期。

7. 发明申请

WO2012021733A2 PHOTODAMAGE MITIGATION COMPOUNDS AND SYSTEMS 审中-公开
标题翻译：光降解减缓化合物和体系
公开(公告)号：WO2012021733A2
公开(公告)日：2012-02-16
申请号：PCT/US2011/047468
申请日：2011-08-11
申请人： PACIFIC BIOSCIENCES OF CALIFORNIA, INC. , YUE, Stephen , WEBER, Robert , KONG, Xiangxu , FEDOROV, Andrei , LYLE, John
发明人： YUE, Stephen , WEBER, Robert , KONG, Xiangxu , FEDOROV, Andrei , LYLE, John
IPC分类号： G01N33/52 , C12Q1/25 , C12Q1/68
CPC分类号： C12Q1/6869 , C12N13/00 , C12Q1/25 , G01N33/52 , G01N33/54373 , G01N2333/91245 , G01N2333/916
摘要： Compositions, devices, systems and methods for reducing and/or preventing photo-induced damage of one or more reactants in an illuminated analytical reaction by addition of one or more photoprotective compounds to the reaction mixture and allowing the reaction to proceed for a period that is less than a photo-induced damage threshold period.
摘要翻译：用于通过向反应混合物添加一种或多种光保护性化合物来减少和/或防止照射分析反应中一种或多种反应物的光致损伤的组合物，装置，系统和方法，反应进行的时间小于光诱导损伤阈值时间。

8. 发明申请

WO2005065072A3 ELECTROSPRAY SYSTEMS AND METHODS 审中-公开
标题翻译：电喷雾系统和方法
公开(公告)号：WO2005065072A3
公开(公告)日：2006-04-27
申请号：PCT/US2004028482
申请日：2004-09-01
申请人： GEORGIA TECH RES INST , FEDOROV ANDREI G , DEGERTEKIN F LEVENT
发明人： FEDOROV ANDREI G , DEGERTEKIN F LEVENT
IPC分类号： B01D59/44 , B01L3/02 , H01J49/00 , H01J49/04 , H01J49/10 , H01L21/302 , H01L21/461
CPC分类号： B05B17/0638 , B01L3/0268 , B01L2400/0439 , B05B5/025 , F23D11/32 , H01J49/0018 , H01J49/165
摘要： Electrospray systems, electrospray structures, removable electrospray structures, methods of operating electrospray systems, and methods of fabricating electrospray systems, are disclosed.
摘要翻译：公开了电喷雾系统，电喷雾结构，可移除电喷雾结构，操作电喷雾系统的方法以及制造电喷雾系统的方法。

9. 发明申请

WO2012009206A3 SEQUENCING REACTIONS WITH ALKALI METAL CATIONS FOR PULSE WIDTH CONTROL 审中-公开
公开(公告)号：WO2012009206A3
公开(公告)日：2012-01-19
申请号：PCT/US2011/043227
申请日：2011-07-07
申请人： PACIFIC BIOSCIENCES OF CALIFORNIA, INC. , FEDOROV, Andrei , LYLE, John , BJORNSON, Keith , HANES, Jeremiah
发明人： FEDOROV, Andrei , LYLE, John , BJORNSON, Keith , HANES, Jeremiah
IPC分类号： C12Q1/68 , C12N15/10 , C12N15/11 , G01N33/84
摘要： Compositions, kits, methods and systems for single molecule nucleotide sequencing comprising producing polymerase reactions having monovalent cations that control the median pulse width for incorporated nucleotides are disclosed. The levels of alkali metals such as lithium, sodium, potassium, rubidium, and cesium in the polymerization are used to control pulse width while allowing other sequencing parameters to remain within a desirable range.

10. 发明申请

WO2009145828A3 TWO SLOW-STEP POLYMERASE ENZYME SYSTEMS AND METHODS 审中-公开
公开(公告)号：WO2009145828A3
公开(公告)日：2009-12-03
申请号：PCT/US2009/002003
申请日：2009-03-30
申请人： PACIFIC BIOSCIENCES OF CALIFORNIA, INC. , BJORNSON, Keith , LEE, Harold , KORLACH, Jonas , TURNER, Stephen , BIBILLO, Arek , CHRISTIANS, Fred , EMIG, Robin , HE, Molly , PARK, Insil , JIA, Lei , FEDOROV, Andrei , LYLE, John
发明人： BJORNSON, Keith , LEE, Harold , KORLACH, Jonas , TURNER, Stephen , BIBILLO, Arek , CHRISTIANS, Fred , EMIG, Robin , HE, Molly , PARK, Insil , JIA, Lei , FEDOROV, Andrei , LYLE, John
IPC分类号： C12Q1/68 , C12N9/12 , C12Q1/48
摘要： Compositions, kits, methods and systems for nucleotide sequencing comprising producing polymerase reactions that exhibit two kinetically observable steps within an observable phase of the polymerase reaction. Two slow step systems can be produced, for example, by selecting the appropriate polymerase enzyme, polymerase reaction conditions including cofactors, and polymerase reaction substrates including the primed template and nucleotides.

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