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1. 发明申请

US20140328782A1 PEPTIDE INHIBITING MATRIX METALLOPROTEANASES ACTIVITY AND USE THEREOF 有权
标题翻译：肽抑制基质金属蛋白酶活性及其用途
公开(公告)号：US20140328782A1
公开(公告)日：2014-11-06
申请号：US14343850
申请日：2011-11-02
申请人： Young Ji Chung , Eun Mi Kim
发明人： Young Ji Chung , Eun Mi Kim
IPC分类号： C07K7/06 , A61Q19/00 , A61K31/728 , A61Q19/02 , A61K38/08 , A61K8/64
CPC分类号： C07K7/06 , A61K8/64 , A61K31/728 , A61K38/00 , A61K38/08 , A61K2800/782 , A61Q19/00 , A61Q19/02 , A61Q19/06 , A61Q19/08
摘要： The present invention relates to a peptide inhibiting a matrix metalloproteanases activity and use thereof. The peptide inhibiting a matrix metalloproteanases activity exhibits an excellent efficacy of improving the condition of skin by directly inhibiting the matrix metalloproteanases activity. In addition, a composition containing the peptide of the invention has excellent bioactivities of inhibiting the activity of hyaluronic acid degrading enzymes, adipogenesis in fat cells, angiogenesis, and the like, thereby being useful for the treatment of various disease such as anti-obesity, anti-cancer, anti-inflammation, and the like, and skin permeability is excellent due to the small size of the peptide, thereby being useful in various fields. The peptide of the invention having excellent activity and safety can be advantageously applied to drugs, quasi-drugs, and cosmetics.
摘要翻译：本发明涉及抑制基质金属蛋白酶活性的肽及其用途。抑制基质金属蛋白酶活性的肽表现出通过直接抑制基质金属蛋白酶活性来改善皮肤状况的优异功效。此外，含有本发明的肽的组合物具有优异的抑制透明质酸降解酶的活性，脂肪细胞中脂肪形成，血管发生等的生物活性，因此可用于治疗各种疾病如抗肥胖，抗癌，抗炎等，并且由于肽的小尺寸，皮肤渗透性优异，因此可用于各种领域。具有优异的活性和安全性的本发明的肽可以有利地应用于药物，准药物和化妆品。

2. 发明申请

US20140255338A1 EDAR LIGAND DERIVED PEPTIDES AND USE THEREOF 有权
标题翻译： EDAR配体衍生肽及其用途
公开(公告)号：US20140255338A1
公开(公告)日：2014-09-11
申请号：US14236406
申请日：2012-05-09
申请人： Yong Ji Chung , Eun Mi Kim
发明人： Yong Ji Chung , Eun Mi Kim
IPC分类号： C07K14/525 , A61Q19/00 , A61Q19/08 , A61K8/64 , A61Q7/00
CPC分类号： A61Q7/00 , A61K8/64 , A61K38/00 , A61Q19/00 , A61Q19/007 , A61Q19/08 , C07K14/525
摘要： The present invention relates to novel peptides derived from an EDAR (EDAR receptor) ligand which belongs to TNF (tumor necrosis factor)-α family and to uses of the same. The present peptides of EDA3 derived from EDA and EDphD1 derived from EDAR ligand possess identical or similar activities to naturally occurring EDA and have much higher stability and skin penetration potency than naturally occurring EDA. Therefore, the composition containing the present peptide not only shows excellent effects on improvement in hair loss and promotion of hair growth, but also has superior efficacies on treatment of an EDA signal transduction pathway-related disorder. In addition, the outstanding activity and stability of the present peptide described above may be greatly advantageous in application to pharmaceutical compositions, quasi-drugs and cosmetics.
摘要翻译：本发明涉及衍生自属于TNF（肿瘤坏死因子）-α家族的EDAR（EDAR受体）配体的新型肽及其用途。衍生自EDA的EDA3和源自EDAR配体的EDphD的本发明肽具有与天然存在的EDA相同或相似的活性，并且具有比天然存在的EDA更高的稳定性和皮肤穿透效力。因此，含有本发明肽的组合物，不仅对改善脱发和促进毛发生长具有优异的效果，而且对于EDA信号转导通路相关病症的治疗也具有优异的效果。此外，上述本发明肽的突出活性和稳定性在用于药物组合物，准药物和化妆品中可能是非常有利的。

3. 发明授权

US08497241B2 WNT10-derived peptide and use thereof 有权
标题翻译： WNT10衍生肽及其用途
公开(公告)号：US08497241B2
公开(公告)日：2013-07-30
申请号：US13393370
申请日：2009-11-24
申请人： Young Ji Chung , Eun Mi Kim , Sang Su Song , Kyoung Mi Cho
发明人： Young Ji Chung , Eun Mi Kim , Sang Su Song , Kyoung Mi Cho
IPC分类号： A61K38/08 , A61P17/00 , A61P17/14 , A61P35/00 , A61P19/10 , A61P19/02 , A61P3/10 , A61Q19/08 , C07K7/06
CPC分类号： A61K8/64 , A61K38/18 , A61Q7/00 , A61Q19/00 , C07K14/475
摘要： The present invention relates to a WNT10-derived peptide, a composition for improving hair loss and skin conditions using the same, and a composition for treating a WNT10 signal transduction pathway-related disorder and DKK-1 protein-induced disorder the same. WNT10-derived peptide of the present invention possesses identical or similar activities to natural-occurring WNT10, and has much higher stability and skin penetration potency than natural-occurring WNT10. Therefore, the composition containing the present peptide not only shows excellent effects on improvement in hair loss (for example, promotion of hair growth or production of hair), but also has superior efficacies on treatment of a WNT10 signal transduction pathway-related disorder and a DKK-1 protein-induced disorder. In addition, the outstanding activity and stability of the present peptide described above may be greatly advantageous in application to pharmaceutical compositions, quasi-drugs and cosmetics.
摘要翻译：本发明涉及WNT10衍生肽，用于改善脱发的组合物和使用该组合物的皮肤状态，以及用于治疗WNT10信号转导途径相关病症和DKK-1蛋白诱导障碍的组合物。本发明的WNT10衍生肽具有与天然存在的WNT10相同或相似的活性，并且具有比天然存在的WNT10高得多的稳定性和皮肤穿透效力。因此，含有本发明肽的组合物对于改善脱发（例如，促进头发生长或毛发生产）显示出优异的效果，而且对治疗WNT10信号转导通路相关病症和 DKK-1蛋白诱导的病症。此外，上述本发明肽的突出活性和稳定性在用于药物组合物，准药物和化妆品中可能是非常有利的。

4. 发明申请

US20130114137A1 POLARIZER HAVING ENHANCED PHOTODURABILITY AND METHOD FOR PREPARING THE SAME 有权
标题翻译：具有增强的可光化性的极化剂及其制备方法
公开(公告)号：US20130114137A1
公开(公告)日：2013-05-09
申请号：US13666334
申请日：2012-11-01
申请人： Chang Seok BAE , Jin Sook KIM , Eun Mi KIM , Pil Joo KIM , Eun Su PARK , Jae Bin SONG
发明人： Chang Seok BAE , Jin Sook KIM , Eun Mi KIM , Pil Joo KIM , Eun Su PARK , Jae Bin SONG
IPC分类号： G02B5/30 , B05D3/12 , B05D5/06
CPC分类号： G02B5/3083
摘要： A polarizer includes boric acid, potassium iodide, and a zinc salt. The zinc salt has a concentration gradient in which the concentration of the zinc salt gradually decreases from a surface of the polarizer to an interior thereof
摘要翻译：偏振片包括硼酸，碘化钾和锌盐。锌盐具有浓度梯度，其中锌盐的浓度从偏振器的表面到其内部逐渐降低

5. 发明授权

US08354142B2 Method for coating polyimide layer using inkjet device 有权
标题翻译：使用喷墨装置涂布聚酰亚胺层的方法
公开(公告)号：US08354142B2
公开(公告)日：2013-01-15
申请号：US12691362
申请日：2010-01-21
申请人： Ki Du Cho , Bong Chul Kim , Hui Jae Lee , Sun Ja Kim , Hwang Un Seo , Hang Sup Cho , Eun Mi Kim
发明人： Ki Du Cho , Bong Chul Kim , Hui Jae Lee , Sun Ja Kim , Hwang Un Seo , Hang Sup Cho , Eun Mi Kim
IPC分类号： B05D5/00
CPC分类号： G02F1/133723 , G02F1/1303 , H01L27/1248
摘要： A method for coating a polyimide layer includes, placing a substrate on a print table; jetting polyimide liquid onto the substrate from a jetting surface provided over the print table; and wiping the jetting surface by moving a wiper from one side of the jetting surface to another side of the jetting surface while the wiper contacts the jetting surface, wherein the wiper is made of one of a perfluoro-based polymer.
摘要翻译：涂布聚酰亚胺层的方法包括：将基材放置在印刷台上; 从设置在所述印刷台上的喷射面喷射聚酰亚胺液体到所述基板上; 并且当擦拭器与喷射表面接触时，通过将擦拭器从喷射表面的一侧移动到喷射表面的另一侧来擦拭喷射表面，其中刮水器由全氟基聚合物之一制成。

6. 发明申请

US20120245086A1 WNT10-Derived Peptide and Use Thereof 有权
标题翻译： WNT10衍生肽及其用途
公开(公告)号：US20120245086A1
公开(公告)日：2012-09-27
申请号：US13393370
申请日：2009-11-24
申请人： Young Ji Chung , Eun Mi Kim , Sang Su Song , Kyoung Mi Cho
发明人： Young Ji Chung , Eun Mi Kim , Sang Su Song , Kyoung Mi Cho
IPC分类号： A61K38/08 , A61P17/00 , A61Q19/08 , A61P17/14 , A61P35/00 , A61P19/10 , A61P19/02 , A61P3/10 , C07K7/06 , A61P19/00
CPC分类号： A61K8/64 , A61K38/18 , A61Q7/00 , A61Q19/00 , C07K14/475
摘要： The present invention relates to a WNT10-derived peptide, a composition for improving hair loss and skin conditions using the same, and a composition for treating a WNT10 signal transduction pathway-related disorder and DKK-1 protein-induced disorder using the same. WNT10-derived peptide of the present invention possesses identical or similar activities to natural-occurring WNT10, and has much higher stability and skin penetration potency than natural-occurring WNT10. Therefore, the composition containing the present peptide not only shows excellent effects on improvement in hair loss (for example, promotion of hair growth or production of hair), but also has superior efficacies on treatment of a WNT10 signal transduction pathway-related disorder and a DKK-1 protein-induced disorder. In addition, the outstanding activity and stability of the present peptide described above may be greatly advantageous in application to pharmaceutical compositions, quasi-drugs and cosmetics.
摘要翻译：本发明涉及WNT10衍生肽，用于改善脱发的组合物和使用该组合物的皮肤状态，以及使用该组合物治疗WNT10信号转导通路相关病症和DKK-1蛋白质诱导障碍的组合物。本发明的WNT10衍生肽具有与天然存在的WNT10相同或相似的活性，并且具有比天然存在的WNT10高得多的稳定性和皮肤穿透效力。因此，含有本发明肽的组合物对于改善脱发（例如，促进头发生长或毛发生产）显示出优异的效果，而且对治疗WNT10信号转导通路相关病症和 DKK-1蛋白诱导的病症。此外，上述本发明肽的突出活性和稳定性在用于药物组合物，准药物和化妆品中可能是非常有利的。

7. 发明申请

US20110312884A1 Noggin-Derived Peptide and Use Thereof 有权
标题翻译： Noggin衍生肽及其用途
公开(公告)号：US20110312884A1
公开(公告)日：2011-12-22
申请号：US13145390
申请日：2009-11-24
申请人： Young Ji Chung , Young Deug Kim , Eun Mi Kim , Sang Su Song , Il Hong , Kyoung Mi Cho , Su Mi Kim , Sang Min Han
发明人： Young Ji Chung , Young Deug Kim , Eun Mi Kim , Sang Su Song , Il Hong , Kyoung Mi Cho , Su Mi Kim , Sang Min Han
IPC分类号： A61K38/10 , C07K7/08 , A61K38/08 , A61P29/00 , A61K8/64 , A61P19/08 , A61Q19/00 , A61Q19/08 , A61Q7/00 , C07K7/06 , A61P17/00
CPC分类号： C07K14/475 , A61K38/00 , C07K5/1019 , C07K2319/00
摘要： Disclosed are a noggin-derived peptide and a composition containing the same for promoting hair growth, improving skin conditions, providing anti-inflammatory function, or preventing or treating bone diseases. The disclosed noggin-derived peptide performs a function identical or similar to that of natural human noggin and is superior in stability and skin permeability as compared thereto. The composition containing the peptide of the present disclosure as an active ingredient exhibits remarkably superior effects in treating, preventing or improving growth factor-related symptoms, e.g. hair loss, skin conditions or cut, or treating, preventing or improving growth factor overexpression-related symptoms. Therefore, the superior activity and stability of the peptide of the present disclosure are greatly advantageous in application to medicine, quasi-drugs and cosmetics.
摘要翻译：公开了一种头蛋白衍生肽和含有其的组合物，其用于促进毛发生长，改善皮肤状况，提供抗炎功能，或预防或治疗骨骼疾病。所公开的头蛋白衍生肽具有与天然人头蛋白相同或相似的功能，并且与其相比具有优异的稳定性和皮肤渗透性。含有本公开的肽作为活性成分的组合物在治疗，预防或改善生长因子相关症状方面表现出显着的优异效果，例如，脱发，皮肤状况或切割，或治疗，预防或改善生长因子过表达相关症状。因此，本公开的肽的优异的活性和稳定性在应用于医药，准药物和化妆品方面是非常有利的。

8. 发明申请

US20100160238A1 TGFP-CAP Peptide and its Uses 有权
标题翻译： TGFP-CAP肽及其用途
公开(公告)号：US20100160238A1
公开(公告)日：2010-06-24
申请号：US12596479
申请日：2007-09-12
申请人： Yong Ji Chung , Young Deug Kim , Eun Mi Kim , Jun Young Choi , Jin Seuk Kim , Sang Su Song , Kyoung Mi Cho
发明人： Yong Ji Chung , Young Deug Kim , Eun Mi Kim , Jun Young Choi , Jin Seuk Kim , Sang Su Song , Kyoung Mi Cho
IPC分类号： C07K14/495 , C07K7/06 , C07K7/08 , A61K38/08 , A61K38/10 , A61K38/16 , A61P37/06 , A61P35/00 , A61P27/06 , A61P19/02 , A61P29/00 , A61P25/28 , A61P17/02 , A61P17/06 , A61P9/10 , A61P1/00
CPC分类号： C07K14/495 , A61K8/64 , A61K38/00 , A61K38/1841 , A61Q19/02 , C07K7/08
摘要： The present invention relates to a GFP-CAP peptide having an amino acid sequence derived from TGF-β1 (transforming growth factor-β1) and a cell adhesion sequence, wherein the amino acid sequence derived from TGF-β1 consists of the amino acid sequence of SEQ ID NO:1 and the TGFP-CAP peptide is represented by the following formula I: Ile-Trp-Ser-Leu-Asp-Thr-Gln-Tyr-Cell adhesion sequence (I). The TGFP-CAP peptide of the present invention exhibits excellent anti-angiogenic activity. In addition, the TGFP-CAP peptide of the present invention prevents effectively melanin generation in skin to have skin whitening effects. The present peptide shows much higher stability and permeability to skin than natural-occurring TGF-β1. Such plausible activities and safety of the present peptide enable advantageously to application to drugs, quasi-drugs and cosmetics.
摘要翻译：本发明涉及具有衍生自TGF-β1（转化生长因子-β1）的氨基酸序列的GFP-CAP肽和细胞粘附序列，其中衍生自TGF-β1的氨基酸序列由的SEQ ID NO：1的氨基酸序列和TGFP-CAP肽由下式I表示：Ile-Trp-Ser-Leu-Asp-Thr-Gln-Tyr-细胞粘附序列（I）。本发明的TGFP-CAP肽表现出优异的抗血管生成活性。此外，本发明的TGFP-CAP肽有效地防止皮肤中的黑色素产生，从而具有皮肤美白效果。本发明的肽比天然存在的TGF-β1显示出更高的对皮肤的稳定性和渗透性。本发明肽的这种合理的活性和安全性有利地适用于药物，准药物和化妆品。

9. 发明申请

US20090137274A1 MOBILE COMMUNICATION DEVICE WITH ENHANCED IMAGE COMMUNICATION CAPABILITY 有权
标题翻译：具有增强图像通信能力的移动通信设备
公开(公告)号：US20090137274A1
公开(公告)日：2009-05-28
申请号：US12359584
申请日：2009-01-26
申请人： Eun-Mi KIM , Yoo-Seok Cho , Dong-Eun Kim , Jung-Pil Yun
发明人： Eun-Mi KIM , Yoo-Seok Cho , Dong-Eun Kim , Jung-Pil Yun
IPC分类号： H04M1/00
CPC分类号： G06F1/1616 , G06F1/1605 , G06F1/1647 , G06F1/165 , G06F1/1681 , G06F1/1686 , G06F1/1692 , H04M1/0218 , H04M1/0245 , H04M2250/16 , H04M2250/52 , H04N2007/145
摘要： A mobile communication device includes a first body, a folder portion rotatably coupled with the first body and positionable between open and closed positions, a first display unit coupled to the folder portion and configured to display first information, and a second display unit coupled to a first side of the first body and configured to receive input and display second information, wherein at least one of text information and graphic information received through the second display unit is displayed on the first display unit.
摘要翻译：移动通信设备包括：第一主体，与第一主体可旋转地联接并且可在打开和关闭位置之间定位的文件夹部分，耦合到文件夹部分并被配置为显示第一信息的第一显示单元，以及耦合到第一主体的第二显示单元第一主体的第一侧，并被配置为接收输入和显示第二信息，其中通过第二显示单元接收的文本信息和图形信息中的至少一个显示在第一显示单元上。

10. 发明授权

US07499074B2 Mobile communication device with enhanced image communication capability 有权
标题翻译：具有增强图像通信功能的移动通信设备
公开(公告)号：US07499074B2
公开(公告)日：2009-03-03
申请号：US11023084
申请日：2004-12-27
申请人： Eun-Mi Kim , Yoo-Seok Cho , Dong-Eun Kim , Jung-Pil Yun
发明人： Eun-Mi Kim , Yoo-Seok Cho , Dong-Eun Kim , Jung-Pil Yun
IPC分类号： H04N7/14 , H04M1/00
CPC分类号： G06F1/1616 , G06F1/1605 , G06F1/1647 , G06F1/165 , G06F1/1681 , G06F1/1686 , G06F1/1692 , H04M1/0218 , H04M1/0245 , H04M2250/16 , H04M2250/52 , H04N2007/145
摘要： The present invention discloses a mobile communication device that allows the user to easily perform simultaneous voice communication and image communication that allows the user to transmit high quality image information to another user and receive high quality image information from another user. The mobile communication device provides multiple cameras and/or display screens that allow a user to easily photograph a subject and view captured images that are received either from a camera located in the device or from another user.
摘要翻译：本发明公开了一种移动通信设备，其允许用户容易地执行语音通信和图像通信，允许用户将高质量的图像信息发送给另一用户，并从另一用户接收高质量的图像信息。移动通信设备提供多个照相机和/或显示屏幕，其允许用户容易地拍摄被摄体并查看从位于设备中的照相机或从另一用户接收的拍摄图像。

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