专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20130011848A1 Optical Instrument Including Excitation Source 有权
标题翻译：包括激发源的光学仪器
公开(公告)号：US20130011848A1
公开(公告)日：2013-01-10
申请号：US13611462
申请日：2012-09-12
申请人： Steven J. Boege , Howard G. King , Eugene F. Young , Johannes P. Sluis , Mark F. Oldham
发明人： Steven J. Boege , Howard G. King , Eugene F. Young , Johannes P. Sluis , Mark F. Oldham
IPC分类号： G01N21/75 , C12M1/40
CPC分类号： G01N21/6486 , B01L7/52 , C12Q2545/101 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/0628 , G01N2201/0635 , Y10S435/808 , Y10S435/809
摘要： An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with excitation beams generated by a light source. The light source can include an area light array of light emitting diodes, one or more solid state lasers, one or more micro-wire lasers, or a combination thereof. According to various embodiments, a Fresnel lens can be disposed along a beam bath between the light source and the reaction regions. Methods of analysis using the optical instrument are also provided.
摘要翻译：提供了一种光学仪器，用于同时用由光源产生的激发光束照射两个或更多个间隔开的反应区域。光源可以包括发光二极管的区域光阵列，一个或多个固态激光器，一个或多个微线激光器，或其组合。根据各种实施例，菲涅耳透镜可以沿着光源和反应区域之间的光束槽设置。还提供了使用光学仪器的分析方法。

2. 发明申请

US20120087832A1 Apparatus and Method for Differentiating Multiple Fluorescence Signals by Excitation Wavelength 有权
标题翻译：通过激发波长区分多个荧光信号的装置和方法
公开(公告)号：US20120087832A1
公开(公告)日：2012-04-12
申请号：US13333788
申请日：2011-12-21
申请人： Howard G. King , Steven J. Boege , Eugene F. Young , Mark F. Oldham
发明人： Howard G. King , Steven J. Boege , Eugene F. Young , Mark F. Oldham
IPC分类号： G01N21/64 , G01N21/63
CPC分类号： G01N21/6428 , B01L7/52 , B01L2300/1805 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6441 , G01N2201/062 , G01N2201/0627 , G01N2201/0628 , Y10S435/808
摘要： An apparatus and method are provided for differentiating multiple detectable signals by excitation wavelength. The apparatus can include a light source that can emit respective excitation light wavelengths or wavelength ranges towards a sample in a sample retaining region, for example, in a well. The sample can contain two or more detectable markers, for example, fluorescent dyes, each of which can be capable of generating increased detectable emissions when excited in the presence of a target component. The detectable markers can have excitation wavelength ranges and/or emission wavelength ranges that overlap with the ranges of the other detectable markers. A detector can be arranged for detecting an emission wavelength or wavelength range emitted from a first marker within the overlapping wavelength range of at least one of the other markers.
摘要翻译：提供一种用于通过激发波长区分多个可检测信号的装置和方法。该装置可以包括可以例如在一个井中的样品保留区域中的样品发射相应的激发光波长或波长范围的光源。样品可以包含两种或更多种可检测的标记，例如荧光染料，其中当荧光染料在靶组分存在下被激发时，其能够产生增加的可检测的发射。可检测标记物可以具有与其它可检测标记物的范围重叠的激发波长范围和/或发射波长范围。可以设置检测器，用于检测在至少一个其他标记的重叠波长范围内从第一标记发射的发射波长或波长范围。

3. 发明申请

US20120021351A1 CONTINUOUS PROCESS FOR PRODUCING TONER USING AN OSCILLATORY FLOW CONTINUOUS REACTOR 有权
标题翻译：使用振荡流连续反应器生产墨粉的连续工艺
公开(公告)号：US20120021351A1
公开(公告)日：2012-01-26
申请号：US12839698
申请日：2010-07-20
申请人： Mark E. Mang , Grazyna Kmiecik-Lawrynowicz , Eugene F. Young , Maura A. Sweeney
发明人： Mark E. Mang , Grazyna Kmiecik-Lawrynowicz , Eugene F. Young , Maura A. Sweeney
IPC分类号： G03G9/08
CPC分类号： G03G9/0804 , G03G9/0819 , G03G9/08711
摘要： The present disclosure provides for oscillatory flow continuous reactors suitable for use in forming emulsion aggregation toners. The reactor may include at least one receptacle being a flexible, tubular member. The reactor may also include a plurality of baffles disposed, at spaced apart intervals, along an interior space of the tubular member, each of the plurality of baffles including one or more orifices. Additionally, one or more fluids may flow through the tubular member. The oscillatory flow continuous reactor may be used in an emulsion aggregation process to produce toner particles.
摘要翻译：本公开提供了适用于形成乳液聚集调色剂的振荡流连续反应器。反应器可以包括至少一个容器，其是柔性管状构件。反应器还可以包括沿着管状构件的内部空间以间隔开的间隔设置的多个挡板，多个挡板中的每一个包括一个或多个孔。另外，一种或多种流体可以流过管状构件。振荡流连续反应器可以用于乳液聚集过程中以产生调色剂颗粒。

4. 发明申请

US20110020744A1 METHODS FOR REDUCING PLASTICIZATION AND BLOCKING IN TONER COMPOSITIONS 有权
标题翻译：减少碳粉组合物中的塑化和阻塞的方法
公开(公告)号：US20110020744A1
公开(公告)日：2011-01-27
申请号：US12898614
申请日：2010-10-05
申请人： Mark E. Mang , Eugene F. Young
发明人： Mark E. Mang , Eugene F. Young
IPC分类号： G03G9/09 , G03G9/08
CPC分类号： G03G9/08755 , G03G9/0817 , G03G9/0821 , G03G9/08782 , G03G9/08797 , G03G9/0904
摘要： Use of a wax in a toner, such as carnauba wax, to give an increase in charge control agent in a toner, such as a magenta toner, to give an increased glass transition temperature is disclosed. The toner may contain a resin comprising amorphous and crystalline polyesters to provide good low melt characteristics.
摘要翻译：公开了在诸如巴西棕榈蜡之类的调色剂中使用蜡以使调色剂如品红色调色剂中的电荷控制剂增加以提高玻璃化转变温度。调色剂可以含有包含无定形和结晶聚酯的树脂，以提供良好的低熔融特性。

5. 发明申请

US20100216143A1 Apparatus and Method for Differentiating Multiple Fluorescence Signals by Excitation Wavelength 审中-公开
标题翻译：通过激发波长区分多个荧光信号的装置和方法
公开(公告)号：US20100216143A1
公开(公告)日：2010-08-26
申请号：US12642009
申请日：2009-12-18
申请人： Howard G. King , Steven J. Boege , Eugene F. Young , Mark F. Oldham
发明人： Howard G. King , Steven J. Boege , Eugene F. Young , Mark F. Oldham
IPC分类号： C12Q1/68 , G01J1/58
摘要： An apparatus and method are provided for differentiating multiple detectable signals by excitation wavelength. The apparatus can include a light source that can emit respective excitation light wavelengths or wavelength ranges towards a sample in a sample retaining region, for example, in a well. The sample can contain two or more detectable markers, for example, fluorescent dyes, each of which can be capable of generating increased detectable emissions when excited in the presence of a target component. The detectable markers can have excitation wavelength ranges and/or emission wavelength ranges that overlap with the ranges of the other detectable markers. A detector can be arranged for detecting an emission wavelength or wavelength range emitted from a first marker within the overlapping wavelength range of at least one of the other markers.
摘要翻译：提供一种用于通过激发波长区分多个可检测信号的装置和方法。该装置可以包括可以例如在一个井中的样品保留区域中的样品发射相应的激发光波长或波长范围的光源。样品可以包含两种或更多种可检测的标记，例如荧光染料，其中当荧光染料在靶组分存在下被激发时，其能够产生增加的可检测的发射。可检测标记物可以具有与其它可检测标记物的范围重叠的激发波长范围和/或发射波长范围。可以设置检测器，用于检测在至少一个其他标记的重叠波长范围内从第一标记发射的发射波长或波长范围。

6. 发明授权

US07498164B2 Instrument for monitoring nucleic acid sequence amplification reaction 有权
标题翻译：监测核酸序列扩增反应的仪器
公开(公告)号：US07498164B2
公开(公告)日：2009-03-03
申请号：US10456196
申请日：2003-06-06
申请人： Mark F. Oldham , Eugene F. Young
发明人： Mark F. Oldham , Eugene F. Young
IPC分类号： C12M1/34 , C12M3/00 , G01N21/64 , G01J1/58 , F21V9/16
CPC分类号： G01N21/6486 , B01L3/5085 , B01L7/52 , C12Q2545/101 , G01N21/274 , G01N21/6428 , G01N21/645 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/0628 , G01N2201/0635 , Y10S435/808 , Y10S435/809
摘要： An instrument is provided that can monitor nucleic acid sequence amplifications reactions, for example, PCR amplification of DNA and DNA fragments. The instrument includes a multi-notch filter disposed along one or both of an excitation beam path and an emission beam path. Methods are also provided for monitoring nucleic acid sequence amplifications using an instrument that includes a multi-notch filter disposed along a beam path.
摘要翻译：提供了可以监测核酸序列扩增反应的仪器，例如DNA和DNA片段的PCR扩增。仪器包括沿激发光束路径和发射光束路径中的一个或两个设置的多陷波滤波器。还提供了使用包括沿着光束路径设置的多陷波滤波器的仪器来监测核酸序列扩增的方法。

7. 发明授权

US07476480B2 Processes for producing toner by treatment with enzyme 有权
标题翻译：用酶处理生产调色剂的方法
公开(公告)号：US07476480B2
公开(公告)日：2009-01-13
申请号：US11651738
申请日：2007-01-09
申请人： Steven M. Malachowski , Amy A. Grillo , Eugene F. Young
发明人： Steven M. Malachowski , Amy A. Grillo , Eugene F. Young
IPC分类号： G03G9/08
CPC分类号： G03G9/0806 , G03G9/0804 , G03G9/08711 , G03G9/08775 , G03G9/08777 , G03G9/08782 , G03G9/08795 , G03G9/08797 , G03G9/09725 , G03G9/09733
摘要： Herein is disclosed a process for producing emulsion aggregation toner including (i) adding a base to an emulsion aggregation toner to increase the pH of the toner to from about 7 to about 12; (ii) sieving and filtering the toner; (iii) washing the toner with an enzyme selected from the group consisting of carboxylic ester hydrolase and sulfuric ester hydrolase; (iv) filtering the toner; (v) washing the toner with reverse osmosis or deionized water; and (vi) adding an acid to reduce the pH of the toner to from about 3 to about 8.
摘要翻译：本文公开了一种生产乳液聚集调色剂的方法，其包括（i）向乳液聚集调色剂中加入碱以将调色剂的pH提高至约7至约12; （ii）筛分和过滤调色剂; （iii）用选自羧酸酯水解酶和硫酸酯水解酶的酶洗涤调色剂; （iv）过滤调色剂; （v）用反渗透或去离子水洗涤调色剂; 和（vi）加入酸以将调色剂的pH降低至约3至约8。

8. 发明申请

US20090009767A1 Optical instrument including excitation source 有权
标题翻译：光学仪器包括激发源
公开(公告)号：US20090009767A1
公开(公告)日：2009-01-08
申请号：US12217410
申请日：2008-07-03
申请人： Steven J. Boege , Howard G. King , Eugene F. Young , Johannes P. Sluis , Mark F. Oldham
发明人： Steven J. Boege , Howard G. King , Eugene F. Young , Johannes P. Sluis , Mark F. Oldham
IPC分类号： G01N21/64
CPC分类号： G01N21/6486 , B01L7/52 , C12Q2545/101 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/0628 , G01N2201/0635 , Y10S435/808 , Y10S435/809
摘要： An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with excitation beams generated by a light source. The light source can include an area light array of light emitting diodes, one or more solid state lasers, one or more micro-wire lasers, or a combination thereof. According to various embodiments, a Fresnel lens can be disposed along a beam bath between the light source and the reaction regions. Methods of analysis using the optical instrument are also provided.
摘要翻译：提供了一种光学仪器，用于同时用由光源产生的激发光束照射两个或更多个间隔开的反应区域。光源可以包括发光二极管的区域光阵列，一个或多个固态激光器，一个或多个微线激光器，或其组合。根据各种实施例，菲涅耳透镜可以沿着光源和反应区域之间的光束槽设置。还提供了使用光学仪器的分析方法。

9. 发明授权

US07008789B2 Instrument for monitoring polymerase chain reaction of DNA 有权
公开(公告)号：US07008789B2
公开(公告)日：2006-03-07
申请号：US10216620
申请日：2002-08-09
申请人： Michael R. Gambini , Susan Atwood Stone, legal representative , Judith K. Atwood, legal representative , Eugene F. Young , Edward J. Lakatos , Anthony L. Cerrone
发明人： John G. Atwood, deceased
IPC分类号： C12M1/34
CPC分类号： G01N21/6428 , B01L3/5085 , B01L7/52 , B01L2200/10 , B01L2300/0654 , B01L2300/0663 , B01L2300/1811 , C12Q1/686 , C12Q2545/101 , G01N21/274 , G01N21/645 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/06113 , G01N2201/0628 , G01N2201/0635 , G01N2201/0636 , G01N2201/068 , C12Q2563/107
摘要： An optical instrument monitors PCR replication of DNA in a reaction apparatus having a temperature cycled block with vials of reaction ingredients including dye that fluoresces in presence of double-stranded DNA. A beam splitter passes an excitation beam to the vials to fluoresce the dye. An emission beam from the dye is passed by the beam splitter to a CCD detector from which a processor computes DNA concentration. A reference strip with a plurality of reference emitters emit reference beams of different intensity, from which the processor selects an optimum emitter for compensating for drift. Exposure time is automatically adjusted for keeping within optimum dynamic ranges of the CCD and processor. A module of the beam splitter and associated optical filters is associated with selected dye, and is replaceable for different dyes.

10. 发明授权

US06965105B2 Scanning system and method for scanning a plurality of samples 有权
标题翻译：用于扫描多个样本的扫描系统和方法
公开(公告)号：US06965105B2
公开(公告)日：2005-11-15
申请号：US10387755
申请日：2003-03-13
申请人： Mark F. Oldham , Eugene F. Young
发明人： Mark F. Oldham , Eugene F. Young
IPC分类号： B01L3/00 , G01N21/25 , G01N21/64 , H01J3/14 , H01J5/16 , H01J40/14
CPC分类号： G01N21/6452 , B01L3/5085 , B01L2200/025 , B01L2300/0806 , B01L2300/0819
摘要： A system for detecting fluorescence emitted from a plurality of samples in a sample tray is provided. The system generally includes a plurality of lenses positioned in a linear arrangement, a linear actuator configured to translate the plurality of lenses, an excitation light source for generating an excitation light, an excitation light direction mechanism for directing the excitation light to a single lens of the plurality of lenses at a time so that a single sample holder aligned with the lens is illuminated at a time, and an optical detection system for analyzing light from the sample holders. In certain embodiments, the optical detection system includes a light dispersing element configured to spectrally disperse the light from the sample holder being illuminated, and a lens element configured to receive light from the light dispersing element and direct the light onto a light detection device. A method of scanning a sample tray having a plurality of samples positioned in sample holders to detect fluorescence is also provided.
摘要翻译：提供了一种用于检测从样品盘中的多个样品发出的荧光的系统。该系统通常包括以线性布置定位的多个透镜，被配置为平移多个透镜的线性致动器，用于产生激发光的激发光源，用于将激发光引导到单个透镜的激发光方向机构一次使多个透镜一次照射与镜片对准的单个样品保持器，以及用于分析来自样品保持器的光的光学检测系统。在某些实施例中，光学检测系统包括光分散元件，其被配置为光谱地分散来自被照亮的样品保持器的光;以及透镜元件，被配置为接收来自光分散元件的光并将光引导到光检测装置。还提供了扫描具有位于样品架中的多个样品以检测荧光的样品盘的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式