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1. 发明授权

US06824553B1 High performance braided catheter 失效
标题翻译：高性能编织导管
公开(公告)号：US06824553B1
公开(公告)日：2004-11-30
申请号：US09648378
申请日：2000-08-25
申请人： Gene Samson , Uriel Hiram Chee , Kim Nguyen , Edward J. Snyder , Erik T. Engelson
发明人： Gene Samson , Uriel Hiram Chee , Kim Nguyen , Edward J. Snyder , Erik T. Engelson
IPC分类号： A61M2900
CPC分类号： A61M25/005 , A61M25/0053 , A61M25/0054 , A61M2025/0081
摘要： This is a catheter assembly and a section of that catheter assembly. That catheter assembly may be used in accessing a tissue target within the body, typically a target which is accessible through the vascular system. Central to the invention is the use of a braided metallic reinforcing member, typically of super-elastic alloy ribbon, situated within the catheter body in such a way to create a catheter having an exceptionally thin wall, controlled stiffness, high resistance to kinking, and complete recovery in vivo from kinking situations. The braid may have a single pitch or may vary in pitch along the axis of the catheter or catheter section. The braided ribbon reinforcing member typically is placed between a flexible outer tubing member and an inner tubing member to produce a catheter section which is very flexible but highly kink resistant. The catheter sections made according to this invention may be used alone or in conjunction with other catheter sections either made using the concepts shown herein or made in other ways. The more proximal sections of the catheter assembly are often substantially stiffer than the more distal sections due to the presence of stiff polymeric tubing or metallic tubing or composited materials in the stiffer section.
摘要翻译：这是导管组件和导管组件的一部分。该导管组件可用于进入体内的组织靶，通常是通过血管系统可接近的靶。本发明的中心是使用位于导管主体内的编织金属加强构件，通常为超弹性合金带，以形成具有特别薄壁，受控刚度，高抗扭结性的导管，以及从扭结情况完全恢复体内。编织物可以具有单个间距，或者可以沿着导管或导管部分的轴线变化。编织带加强构件通常放置在柔性外管构件和内管构件之间以产生非常柔性但高度扭结的导管部分。根据本发明制造的导管部分可以单独使用或与使用本文所示的概念或以其他方式制成的其它导管部分结合使用。由于在刚性部分中存在刚性聚合物管或金属管或合成材料，所以导管组件的近端部分通常比较远的部分更坚硬。

2. 发明授权

US06409721B1 Process for forming an occlusion in a body cavity 失效
标题翻译：在体腔中形成闭塞的方法
公开(公告)号：US06409721B1
公开(公告)日：2002-06-25
申请号：US09523540
申请日：2000-03-10
申请人： E. Thomas Wheelock , Erik T. Engelson , Harold F. Carrison
发明人： E. Thomas Wheelock , Erik T. Engelson , Harold F. Carrison
IPC分类号： A61B1814
CPC分类号： A61B17/12022 , A61B17/1214 , A61B2017/12063
摘要： This invention is an apparatus for the formation of occlusions in spaces in the human body, occluding such as thrombi in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas. In particular, it deals with a one piece assembly having an improved electrolytically erodable link to an occlusive member and further having an incorporated return electrode in the assembly. The occlusion-forming member is introduced to and is intended to remain at the desired occlusion site. The invention also relates to the joint itself. The invention further includes a method for introduction and electrolytic separation of the device.
摘要翻译：本发明是一种用于在人体空间中形成闭塞的装置，阻塞动脉，静脉，动脉瘤，血管畸形和动静脉瘘等血栓。特别地，它涉及具有改进的电解腐蚀性连接到闭塞构件的一体式组件，并且在组件中还具有并入的返回电极。将闭塞形成构件引入并且旨在保留在期望的闭塞部位。本发明还涉及接头本身。本发明还包括用于引入和电解分离该装置的方法。

3. 发明授权

US6066158A Mechanical clot encasing and removal wire 失效
标题翻译：机械凝块包裹和去除线
公开(公告)号：US6066158A
公开(公告)日：2000-05-23
申请号：US686304
申请日：1996-07-25
申请人： Erik T. Engelson , Gene Samson
发明人： Erik T. Engelson , Gene Samson
IPC分类号： A61B17/22 , A61F2/958 , A61M29/00 , A61M29/02
CPC分类号： A61B17/3207 , A61B17/221 , A61B17/320725 , A61B17/32075 , A61B2017/22034 , A61B2017/22061 , A61B2017/2212 , A61M2025/1095 , A61M25/10 , A61M29/02
摘要： This is a surgical device usually delivered through an intravascular catheter. It is designed to pierce and remove emboli often found in tortuous vasculature. The device includes several sections. The device has a core element. Placed around the distal end of the core wire is a collapsible but self expanding embolism collection assembly. That collector assembly is typically joined to the core wire at its distal end. The collector assembly may have a generally conical distal portion when expanded and may have a proximal section having varied purposes, e.g. for centering the collector assembly in the vascular lumen. The assembly further may have an actuator which permits the collector assembly to expand after deployment.
摘要翻译：这是通常通过血管内导管递送的手术装置。它旨在刺穿和去除经常在弯曲脉管系统中发现的栓子。该设备包括几个部分。该设备具有核心元件。放置在芯线远端的是可折叠但自膨胀的栓塞收集组件。该集电器组件通常在其远端处连接到芯线。收集器组件可以在膨胀时具有大致锥形的远侧部分，并且可以具有不同目的的近端部分，例如，用于将收集器组件对准在血管腔中。组件还可以具有致动器，其允许收集器组件在展开之后膨胀。

4. 发明授权

US6030369A Micro catheter shaft 失效
标题翻译：微导管轴
公开(公告)号：US6030369A
公开(公告)日：2000-02-29
申请号：US887950
申请日：1997-07-03
申请人： Erik T. Engelson , Mark Carter
发明人： Erik T. Engelson , Mark Carter
IPC分类号： A61M25/00 , A61M25/16 , A61M5/00
CPC分类号： A61M25/0045 , A61M2025/0042 , A61M25/0009
摘要： This is a catheter having a shaft, the layers of which are coextruded in an intermittently changing pattern that produces particular mechanical and frictional properties in the structure. The outer layer of the catheter shaft is comprised of a material which has greater flexibility than the material which comprises the inner layer of the catheter shaft. The stiffer material which comprises the inner layer has frictional properties which facilitate guidewire passage and control. The invention includes the substituent shaft per se and a method of making the shaft.
摘要翻译：这是具有轴的导管，其轴线以间歇变化的图案共挤出，在结构中产生特定的机械和摩擦特性。导管轴的外层由与包括导管轴的内层的材料相比具有更大柔性的材料构成。包含内层的更硬的材料具有促进导丝通过和控制的摩擦性能。本发明包括取代轴本身以及制造轴的方法。

5. 发明授权

US5984929A Fast detaching electronically isolated implant 失效
标题翻译：快速分离电子隔离植入物
公开(公告)号：US5984929A
公开(公告)日：1999-11-16
申请号：US941458
申请日：1997-09-30
申请人： Mehran Bashiri , Michael P. Wallace , Pete Phong Pham , Cong Thach , Chad C. Roue , Erik T. Engelson
发明人： Mehran Bashiri , Michael P. Wallace , Pete Phong Pham , Cong Thach , Chad C. Roue , Erik T. Engelson
IPC分类号： A61B17/12 , A61F2/01 , A61F2/02 , A61F2/06 , A61F2/84 , A61B17/00
CPC分类号： A61F2/95 , A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/1215 , A61B17/12154 , A61F2/01 , A61B2017/12063 , A61F2002/011 , A61F2002/016 , A61F2002/9505 , A61F2230/0006 , A61F2230/005 , A61F2230/0069 , A61F2230/0091
摘要： This is an implant for placement in the human body and an assembly for so placing that implant. Most desirably, it is an implant for use in the vasculature of the human body and is used to occlude some space in that vasculature as a portion of a treatment regimen. The implant itself is preferably a component of a deployment device using an electrolytically severable joint. The implant is electrically isolated from the electrolytically severable joint by a highly resistive or insulative layer. Such isolation and minimization of the conductive pathway from the placement apparatus to the body's fluids appears to enhance the susceptibility of the electrolytic joint to quick erosion and detachment of the implant from the deployment media. Although the implant itself is preferably a vaso-occlusive device, it may instead be a stent, a vena cava filter, or other implant which may be installed in this manner.
摘要翻译：这是用于放置在人体中的植入物和用于使得植入物放置的组件。最理想的是，它是用于人体脉管系统的植入物，并且用于封闭该脉管系统中的一些空间作为治疗方案的一部分。植入物本身优选是使用电解可分割接头的展开装置的部件。植入物通过高电阻或绝缘层与电解可分离的接头电隔离。从放置装置到身体的流体的导电通路的这种隔离和最小化似乎增强了电解接头对植入物从展开介质的快速侵蚀和分离的敏感性。虽然植入物本身优选为血管闭塞装置，但它可以是支架，腔静脉过滤器或可以以这种方式安装的其它植入物。

6. 发明授权

US5749849A Variable stiffness balloon catheter 失效
标题翻译：可变刚度球囊导管
公开(公告)号：US5749849A
公开(公告)日：1998-05-12
申请号：US557075
申请日：1996-08-12
申请人： Erik T. Engelson
发明人： Erik T. Engelson
IPC分类号： A61M25/00 , A61M29/02 , A61M31/00
CPC分类号： A61M29/02 , A61M25/0045 , A61M25/0054 , A61M2025/0079 , A61M2025/1063
摘要： This invention is a single-lumen balloon catheter and assembly having a variable stiffness shaft that allows for greater guidewire trackability and proximal pushability than previous designs. The catheter has an elongate tubular body that is made of inner and outer coaxial tubes, the inner tube being made of proximal and distal sections, the proximal section being stiffer than the distal section and the distal section being stiffer than the outer tube.
摘要翻译： PCT No.PCT / US94 / 05679 Sec。 371日期：1996年8月12日 102（e）日期1996年8月12日PCT 1994年5月20日PCT公布。公开号WO94 / 27668 日期1994年12月8日本发明是具有可变刚度轴的单腔气囊导管和组件，其允许比以前的设计更大的导丝跟踪性和近端推挤性。导管具有由内外同轴管制成的细长管状体，内管由近端和远端部分制成，近端部分比远端部分更硬，远端部分比外管更硬。

7. 发明授权

US5261916A Detachable pusher-vasoocclusive coil assembly with interlocking ball and keyway coupling 失效
标题翻译：具有互锁球和键槽联轴器的可拆卸推动器 - 血管闭塞线圈组件
公开(公告)号：US5261916A
公开(公告)日：1993-11-16
申请号：US806912
申请日：1991-12-12
申请人： Erik T. Engelson
发明人： Erik T. Engelson
IPC分类号： A61B17/03 , A61B17/12 , A61F2/88 , A61F2/95 , A61M25/12 , A61M25/14 , A61M29/00 , A61B17/00
CPC分类号： A61B17/12022 , A61B17/1214 , A61F2/88 , A61F2/95 , A61B2017/1205 , A61B2017/12054 , A61F2002/9505
摘要： A pusher-vasoocclusive coil assembly that is advanced through a catheter to a site within a vessel and is manipulated to detach the coil from the assembly. The coil has an enlarged member at its proximal end and the pusher has a keyway at its distal end that receives the enlarged member in interlocking engagement. The pusher and coil are coupled by placing the enlarged member in the keyway and enclosing the coupled assembly with a coaxial sleeve. The coil-pusher-sleeve assembly is positioned at the site and the sleeve is retracted to allow the member to move out of the keyway to uncouple the pusher and coil.
摘要翻译：推进器 - 血管收缩线圈组件，其通过导管前进到血管内的部位，并被操纵以将线圈从组件分离。线圈在其近端具有扩大的构件，并且推动器在其远端具有键槽，其接合互锁接合的扩大构件。推动器和线圈通过将扩大构件放置在键槽中并且用同轴套筒封闭联接组件而联接。线圈推动器 - 套筒组件定位在该位置处并且套筒缩回以允许构件移出键槽以使该推动器和线圈脱开。

8. 发明授权

US4739768A Catheter for guide-wire tracking 失效
标题翻译：导丝跟踪导管
公开(公告)号：US4739768A
公开(公告)日：1988-04-26
申请号：US869597
申请日：1986-06-02
申请人： Erik T. Engelson
发明人： Erik T. Engelson
IPC分类号： A61M25/01 , A61M25/00 , A61B6/00
CPC分类号： A61M25/09 , A61M25/0045 , A61M2025/0047 , A61M2025/0048
摘要： A catheter for use with a guide wire which can be guided from an external body access site to an internal tissue, and into the tissue along a tortuous path of at least about 5 cm through vessels of less than about 3 mm lumen inner diameter. The catheter includes a relatively stiff proximal segment dimensioned to track the wire from the access site to a region adjacent the internal tissue, and a relatively flexible distal segment dimensioned to track the wire along the tortuous path within the soft tissue.
摘要翻译：一种用于导线的导管，其可以从外部身体进入部位被引导到内部组织，并且沿着至少约5cm的曲折路径通过小于约3mm管腔内径的血管进入组织。导管包括相对刚性的近端段，其尺寸适于跟踪从进入位置到邻近内部组织的区域的线，以及尺寸适于沿着软组织内的曲折路径跟踪线的相对柔性的远侧段。

9. 发明授权

US4655746A Catheter device 失效
标题翻译：导管装置
公开(公告)号：US4655746A
公开(公告)日：1987-04-07
申请号：US803816
申请日：1985-12-02
申请人： John R. Daniels , Erik T. Engelson , Garbriel B. Vegh
发明人： John R. Daniels , Erik T. Engelson , Garbriel B. Vegh
IPC分类号： A61F2/958 , A61M1/36 , A61M25/00
CPC分类号： A61M25/1011 , A61M1/3615
摘要： A catheter device for transferring fluid material to or from one or more selected-length segment of a vessel. The device includes first and second catheters, each having a tube with distal and proximal ends, an inflatable balloon carried on the tube, adjacent the distal tube end, and a fluid conduit for supplying the balloon, with such operatively positioned in the vessel. A central region of the second-catheter tube is axially shiftable within the first-catheter tube, allowing the balloons to be placed at desired relative positions in the vessel. Fluid is injected into the region between the two balloons through a fluid passageway formed in a channel in the first-catheter tube.
摘要翻译：一种导管装置，用于将流体材料输送到或从容器的一个或多个选定长度的段进行传送。该装置包括第一和第二导管，每个导管具有带有远端和近端的管，邻近远端管端承载在管上的可膨胀气囊，以及用于供应气囊的流体导管，可操作地定位在容器中。第二导管管的中心区域在第一导管管内可轴向移动，允许气囊放置在容器中期望的相对位置。流体通过形成在第一导管中的通道中的流体通道注入到两个气囊之间的区域中。

10. 发明授权

US6096034A Aneurysm closure device assembly 失效
标题翻译：动脉瘤闭合装置组装
公开(公告)号：US6096034A
公开(公告)日：2000-08-01
申请号：US96806
申请日：1998-06-12
申请人： David Kupiecki , Clifford Teoh , Hong Doan , Son M. Gia , Erik T. Engelson , Uriel Hiram Chee , Mehran Bashiri , Joseph C. Eder
发明人： David Kupiecki , Clifford Teoh , Hong Doan , Son M. Gia , Erik T. Engelson , Uriel Hiram Chee , Mehran Bashiri , Joseph C. Eder
IPC分类号： A61B17/00 , A61B17/12 , A61F2/00 , A61F2/06 , A61F2/82 , A61F2/88 , A61L29/00 , A61M31/00
CPC分类号： A61F2/88 , A61B17/12022 , A61B17/12118 , A61B17/12145 , A61B17/12154 , A61B2017/12063 , A61F2002/30092 , A61F2210/0014 , A61F2250/0039 , A61F2310/00023
摘要： This is an artificial occlusion kit for implanting and retaining an artificial occlusion device in a body space adjacent to and extending from a body lumen in a mammal. The includes at least one occlusion device and a retaining device for blocking the migration of the occlusion device out of the occlusion site. The retaining device is radially expandable at a retaining site adjacent the body space to be occluded to a diameter that is sufficient to engage the body lumen wall at the retaining site and form a barrier across the entrance zone of the body space to be occluded. The expanded retaining device also forms a lumen for flow through body lumen at the retaining site. The retaining device may be placed in the body temporarily or permanently. At least one semi-penetrable space may also be provided in the retaining device, allowing introduction of occlusion devices into the body space to be occluded, but preventing subsequent migration of the occlusion devices out of the body space. This semi-penetrable space may also be distensible to allow for delivery of occlusion devices therethrough. An introducer wire or a tapered-tip delivery catheter may be used to distend the distensible space and deliver the occlusion devices. The retaining device structure may further include a radiopaque metal wire wound into a primary helix over an inner core member made of a superelastic alloy of nickel and titanium.
摘要翻译：这是一种用于将人工闭塞装置植入和保持在与哺乳动物的体腔相邻并从其延伸的身体空间中的人造闭塞套件。包括至少一个闭塞装置和用于阻挡闭塞装置移出闭塞部位的保持装置。保持装置可以在靠近身体空间的保持位置处径向展开，以被阻塞到直径足以与保持位置处的身体腔壁接合并形成穿过要被遮挡的身体空间的入口区域的屏障。扩张的保持装置还形成用于在保留位置处流过体腔的流明。保持装置可以临时或永久地放置在身体中。还可以在保持装置中设置至少一个半透入空间，从而允许将遮挡装置引入身体空间以被阻塞，但是防止闭塞装置随后从身体空间中移出。这种半透入空间也可以是可扩张的，以允许通过其中的封闭装置的输送。导引线或锥形输送导管可用于扩张可扩张空间并输送遮挡装置。保持装置结构还可以包括在由镍和钛的超弹性合金制成的内芯构件上缠绕到主螺旋中的不透射线金属线。

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