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1. 发明专利

SE515949C2 未知
公开(公告)号：SE515949C2
公开(公告)日：2001-10-29
申请号：SE0002771
申请日：2000-07-26
申请人： SVEN ERIK HOLMGREN , JONSSON TORD
发明人： HOLMGREN SVEN-ERIK , JONSSON TORD
IPC分类号： B60D1/02
摘要： The present invention concerns a trailer hitch for heavy vehicles, which exhibits a coupling housing arranged on the traction vehicle comprising a rear, vertical end piece from which extend's an upper, forward protruding coupling yoke piece and a lower, forward protruding coupling yoke piece, between which a low eye on a trailer and a low ball arranged in the tow eye are intended to be secured by means of a coupling pin running through a hole in the tow ball. In accordance with the invention, the trailer hitch is characterised by the following distinctive features: A principally vertical wedge (12) that is arranged between both coupling yoke pieces (3, 4) in front of the rear end piece (2) and is so designed that the wedging action increases, i.e. the force of the wedge increases as the wedge is pressed down; An intermediate piece (14) equipped partly with an upper forward protruding part (15) and partly a lower forward protruding part (17) is arranged between the wedge (12) and the tow ball (6) whereby the said parts are intended to abut against an upper (16) and a lower (18) part of the tow ball: The wedge (12) exhibits a spring device (13) acting on its top and intending to press down the wedge.

2. 发明专利

SE9302220D0 未知
公开(公告)号：SE9302220D0
公开(公告)日：1993-06-28
申请号：SE9302220
申请日：1993-06-28
申请人： SVEN-ERIK HOLMGREN
发明人： SVEN-ERIK *HOLMGREN
IPC分类号： B09B1/00 , B09C1/02

3. 发明授权

US07070976B2 Matrix metalloproteinase polypeptide 失效
标题翻译：基质金属蛋白酶多肽
公开(公告)号：US07070976B2
公开(公告)日：2006-07-04
申请号：US10791980
申请日：2004-03-03
申请人： Timothy Wood , Jonas Ekblom , Erik Holmgren , Mats Kihlén
发明人： Timothy Wood , Jonas Ekblom , Erik Holmgren , Mats Kihlén
IPC分类号： C12N9/64
CPC分类号： C12N9/6491 , C12N2799/021
摘要： The present invention provides genes encoding novel matrix metalloproteinases termed MMP; constructs and recombinant host cells incorporating the genes; the MMP polypeptides encoded by the genes; antibodies to the MMP polypeptides; and methods of making and using all of the foregoing.
摘要翻译：本发明提供了编码称为MMP的新型基质金属蛋白酶的基因; 构建体和掺入该基因的重组宿主细胞; 由该基因编码的MMP多肽; MMP多肽的抗体; 以及制作和使用上述所有方法。

4. 发明申请

US20060275869A1 Novel matrix metalloproteinases 审中-公开
公开(公告)号：US20060275869A1
公开(公告)日：2006-12-07
申请号：US11481859
申请日：2006-07-05
申请人： Timothy Wood , Jonas Ekblom , Erik Holmgren , Mats Kihlen
发明人： Timothy Wood , Jonas Ekblom , Erik Holmgren , Mats Kihlen
IPC分类号： C12P21/06 , C12N9/64 , C07H21/04 , C12N15/86
CPC分类号： C12N9/6491 , C12N2799/021
摘要： The present invention provides genes encoding novel matrix metalloproteinases termed MMP; constructs and recombinant host cells incorporating the genes; the MMP polypeptides encoded by the genes; antibodies to the MMP polypeptides; and methods of making and using all of the foregoing.

5. 发明授权

US06492424B1 Glucocorticoid and thyroid hormone receptor ligands for the treatment of metabolic disorders 失效
标题翻译：糖皮质激素和甲状腺激素受体配体用于治疗代谢紊乱
公开(公告)号：US06492424B1
公开(公告)日：2002-12-10
申请号：US09744865
申请日：2001-04-09
申请人： Theresa Apelqvist , Patrick Goede , Erik Holmgren
发明人： Theresa Apelqvist , Patrick Goede , Erik Holmgren
IPC分类号： A61K3119
CPC分类号： C07D295/192 , C07C59/68 , C07C59/90 , C07C65/40 , C07C69/736 , C07C69/92 , C07C217/90 , C07C233/56 , C07C235/34
摘要： Novel glucocorticoid and thyroid receptor ligands as provided which have the general formula (I): in which R1 is an aliphatic hydrocarbon, an aromatic hydrocarbon, carboxylic acid or ester thereof, alkenyl carboxylic acid or ester thereof, hydroxy, halogen, or cyano, or a pharmaceutically acceptable salt thereof. R2 and R3 are the same or different, and are hydrogen, halogen, alkyl of 1 to 4 carbons, or cycloalkyl of 3 to 5 carbons, at least one of R2 and R3 being other than hydrogen. X is carbonyl or methylene. R4 is an aliphatic, aromatic or heteroaromatic. Y is hydroxyl, methoxy, amino, or alkyl amino. n is an integer from 0 to 4. A method for treating diseases associated with metabolism dysfunction or which are dependent on the expression of a glucocorticoid or thyroid receptor gene such as diabetes, hypercholesterolemia, or obesity using these compounds is also disclosed.
摘要翻译：提供具有通式（I）的新型糖皮质激素和甲状腺受体配体：其中R 1是脂族烃，芳族烃，羧酸或其酯，链烯基羧酸或其酯，羟基，卤素或氰基，或其药学上可接受的盐。 R2和R3相同或不同，为氢，卤素，1至4个碳的烷基或3至5个碳的环烷基，R2和R3中的至少一个不是氢。 X是羰基或亚甲基。 R 4是脂族，芳族或杂芳族。 Y是羟基，甲氧基，氨基或烷基氨基。 n是0至4的整数。还公开了用于治疗与代谢功能障碍相关的疾病或依赖于使用这些化合物的糖皮质激素或甲状腺受体基因如糖尿病，高胆固醇血症或肥胖症的表达的方法。

6. 发明授权

US5721114A Expression system for producing apolipoprotein AI-M 失效
标题翻译：载脂蛋白AI-M的表达系统
公开(公告)号：US5721114A
公开(公告)日：1998-02-24
申请号：US448606
申请日：1995-08-25
申请人： Lars Abrahamsen , Erik Holmgren , Christina Kalderen , Mats Lake , .ANG.sa Mikaelsson , Torsten Sejlitz
发明人： Lars Abrahamsen , Erik Holmgren , Christina Kalderen , Mats Lake , .ANG.sa Mikaelsson , Torsten Sejlitz
IPC分类号： C12N15/09 , C07K14/775 , C12N1/21 , C12N15/12 , C12N15/71 , C12P21/02 , C12R1/19 , C12R1/91 , C12P21/06 , C07H21/04 , C12N1/20 , C12N15/00
CPC分类号： C07K14/775 , C12N15/71 , C07K2319/02
摘要： The invention relates to an expression system giving high extracellular production of apolipoprotein AI-M (Milano) using E. coli and comprises a plasmid carrying an origin of replication, an inducible promoter sequence, a DNA sequence coding for a signal peptide, a DNA sequence coding for apolipoprotein AI-M, and a transcription terminator. The invention also relates to a method of producing apolipoprotein AI-M using the expression system.
摘要翻译： PCT No.PCT / SE93 / 01061 Sec。 371日期1995年8月25日 102（e）日期1995年8月25日PCT 1993年12月9日PCT公布。第WO94 / 13819号公报日期：1994年6月23日本发明涉及使用大肠杆菌提供载脂蛋白AI-M（Milano）的高细胞外产生的表达系统，并且包含携带复制起点的质粒，诱导型启动子序列，编码信号的DNA序列肽，编码载脂蛋白AI-M的DNA序列和转录终止子。本发明还涉及使用表达系统产生载脂蛋白AI-M的方法。

7. 发明授权

US5411732A Preparation of fused proteins, antibodies and processes therefore 失效
标题翻译：因此制备融合蛋白，抗体和过程
公开(公告)号：US5411732A
公开(公告)日：1995-05-02
申请号：US130430
申请日：1993-10-01
申请人： Bjorn Lowenadler , Erik Holmgren , Mathias Uhlen , Bjorn Nilsson
发明人： Bjorn Lowenadler , Erik Holmgren , Mathias Uhlen , Bjorn Nilsson
IPC分类号： C07K14/575 , A61K39/00 , C07K14/00 , C07K14/195 , C07K14/31 , C07K14/41 , C07K14/65 , C07K16/00 , C07K16/44 , C07K19/00 , C12N15/00 , C12N15/09 , C12P21/00 , C12P21/02 , C12R1/19 , G01N33/531 , G01N33/577
CPC分类号： A61K39/00 , A61K39/0005 , C07K14/31 , C07K14/65 , C07K16/44 , A61K2039/6068
摘要： A process for preparing antibodies specific for an amino acid sequence which comprises immunizing a mammal with a fused protein comprising said amino acid sequence fused to an immunogenic IgG binding protein is disclosed.
摘要翻译：公开了一种制备对氨基酸序列特异性的抗体的方法，其包括用包含与免疫原性IgG结合蛋白融合的所述氨基酸序列的融合蛋白免疫哺乳动物。

8. 发明申请

US20100281609A1 Cover Intended for a Pool Unit within a Pool System 审中-公开
标题翻译：池系统中的池单元的封面
公开(公告)号：US20100281609A1
公开(公告)日：2010-11-11
申请号：US11992613
申请日：2006-09-14
申请人： Lars Erik Holmgren
发明人： Lars Erik Holmgren
IPC分类号： E04H4/10
CPC分类号： E04H4/10 , E04H4/106 , E04H4/129 , F24S10/17 , F24S10/73 , F24S20/50 , Y02E10/44
摘要： The present invention relates to a cover (10) intended for a pool system (1), the cover being lightly flexible and formed as a pool-covering structure and serving as a protection, where said cover (10) is adapted to cooperate in edge-related fashion with a guide arrangement (11) or similar means, said cover (10) being oriented by support means (112) at a predetermined distance from the upper surface of a body of liquid or body of water enclosed by the pool. Said cover is integrally formed with and/or adapted to support liquid-Tillable or liquid-filled channels (14, 14a) where said channels are adapted to be included in one or more thermal energy absorbing units (6a) included in one or more suntrap apparatuses (6). A liquid in these liquid-filled channels (14), heated by solar energy, is adapted to be heat exchanged with said body of liquid or body of water (2) enclosed by the pool.
摘要翻译：本发明涉及一种用于游泳池系统（1）的盖子（10），该盖子轻微柔性并形成为一个游泳池覆盖结构并用作保护，其中所述盖子（10）适于在边缘与导向装置（11）或类似装置相关联的方式，所述盖（10）由支撑装置（112）定位，距离由池围绕的液体或水体的上表面预定的距离。所述盖整体形成有和/或适于支撑液体可填充或液体填充的通道（14,14a），其中所述通道适于包括在包含在一个或多个分束器中的一个或多个热能吸收单元（6a）中装置（6）。在这些由太阳能加热的液体填充通道（14）中的液体适于与由池围绕的液体或水体（2）进行热交换。

9. 发明授权

US06739614B2 Trailer hitch 失效
标题翻译：拖车搭便车
公开(公告)号：US06739614B2
公开(公告)日：2004-05-25
申请号：US10333822
申请日：2003-04-02
申请人： Sven-Erik Holmgren , Tord Jonsson
发明人： Sven-Erik Holmgren , Tord Jonsson
IPC分类号： B60D102
CPC分类号： B60D1/241 , B60D1/02
摘要： A trailer hitch for heavy vehicles has a coupling housing arranged on the traction vehicle with a rear, vertical end piece from which extends an upper, forward protruding coupling yoke piece and a lower, forward protruding coupling yoke piece, between which a tow eye on a trailer and a tow ball arranged in the tow eye are intended to be secured by means of a coupling pin running through a hole in the tow ball. A principally vertical wedge (12) is arranged between both coupling yoke pieces (3, 4) in front of the rear end piece (2) and is so designed that the wedging action increases, i.e. the force of the wedge increases, as the wedge is pressed down. An intermediate piece (14), equipped partly with an upper, forward protruding part (15) and partly a lower, forward protruding part (17), is arranged between the wedge (12) and the tow ball (6), whereby the parts are intended to abut against an upper (16) and a lower (18) part of the tow ball. The wedge (12) exhibits a spring device (13) acting on its top and intending to press down the wedge.
摘要翻译：用于重型车辆的挂车挂钩具有布置在牵引车辆上的联接器壳体，其具有后部垂直端部件，从其延伸了上部，前部突出的联接轭架件和下部，前部突出的联接轭架件，布置在拖曳眼睛中的拖车和拖曳球旨在通过穿过拖曳球中的孔的联接销固定。在后端件（2）的前面的两个联接轭件（3,4）之间布置有一个主要的垂直楔形件（12），并且被设计成楔形作用增加，即楔形件的力增加，楔形件被按下。设置在楔形件（12）和拖曳球（6）之间的部分地具有上部前部突出部分（15）和部分下部前部突出部分（17）的中间件（14），由此部件旨在抵靠拖曳球的上部（16）和下部（18）部分。楔形物（12）表现出弹簧装置（13），其作用在其顶部并且有意压下楔形物。

10. 发明授权

US06734005B2 Matrix metalloproteinases 失效
标题翻译：基质金属蛋白酶
公开(公告)号：US06734005B2
公开(公告)日：2004-05-11
申请号：US09862631
申请日：2001-05-22
申请人： Timothy Wood , Jonas Ekblom , Erik Holmgren , Mats Kihlén
发明人： Timothy Wood , Jonas Ekblom , Erik Holmgren , Mats Kihlén
IPC分类号： C07A2104
CPC分类号： C12N9/6491 , C12N2799/021
摘要： The present invention provides genes encoding novel matrix metalloproteinases termed MMP; constructs and recombinant host cells incorporating the genes; the MMP polypeptides encoded by the genes; antibodies to the MMP polypeptides; and methods of making and using all of the foregoing.
摘要翻译：本发明提供了编码称为MMP的新型基质金属蛋白酶的基因; 构建体和掺入该基因的重组宿主细胞; 由该基因编码的MMP多肽; MMP多肽的抗体; 以及制作和使用上述所有方法。

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