会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 1. 发明公开
    • An arrangement for setting the nips of the rollers of sheet manipulating apparatus
    • Vorrichtung zum Einstellen der Walzenspalten a einer blattbearbeitenden Maschine。
    • EP0118999A1
    • 1984-09-19
    • EP84300772.5
    • 1984-02-07
    • Cove, Eric BenjaminMORGANA SYSTEMS LIMITED
    • Cove, Eric BenjaminReynolds, Richard Austin
    • B65H45/16
    • B65H45/144B65H45/148
    • An arangement for the remote control of the setting of the nip between a fixed roller (57) and an adjustable roller (58) of apparatus which manipulates i.e. folds, slits, scores, perforates or deflects of paper, cardboard or the like, comprises a caliper (64) coupled to the adjustable roller and having a gap (66) the dimension of which varies in accordance with the dimension of the nip. By opening the caliper land inserting a specimen of a sheet in the gap the nip between the rollers is adjusted automatically to suit the specimen. The movable arm (72) of the caliper is formed by a block in which a spindle (73) of the movable roller is journalled and which is moved by a cam (77) operated by a handle acting through a Bowden cable (79).
    • 用于遥控固定辊(57)和可操纵纸张,纸板等的折叠,狭缝,刻痕,穿孔或偏转的设备的可调节辊(58)之间的辊隙的设置的布置包括: 联接到可调节辊的卡钳(64)具有间隙(66),该间隙的尺寸根据辊隙的尺寸而变化。 通过打开卡钳并将片材的样品插入间隙中,辊之间的辊隙被自动调节以适合样品。 卡钳的可移动臂(72)由块体形成,其中可动辊的主轴(73)被支承并且由通过鲍登缆线(79)作用的手柄操作的凸轮(77)移动。
    • 2. 发明公开
    • Buckle plate for sheet manipulating apparatus
    • Stauchfalztaschefüreine blattbearbeitende Maschine。
    • EP0118228A1
    • 1984-09-12
    • EP84300773.3
    • 1984-02-07
    • Cove, Eric BenjaminMORGANA SYSTEMS LIMITED
    • Garratt, Paul StuartCove, Eric Benjamin
    • B65H45/16
    • B65H45/144B65H45/148
    • A buckle plate (8 or 9), for use in a machine which manipulates i.e. folds or deflects sheets of paper, cardboard or the like, comprises a rectangular frame (81) having a multiplicity of pairs of transversely extending guide members (84) between which a sheet slides. A carrier (88) extending transversely of the guide members supports a plurality of sheet control members (89) in spaces between the guide members so that the control members can be moved between a first position in which they form deflecting surfaces for deflecting a sheet and a second position in which they act as stop members for locating a sheet to be folded. The second position is adjustable in accordance with the size of the sheet and the position of the fold. The carrier is slidably mounted in the frame so that the control members can be moved in unison between the first and second positions.
    • 用于机器的带扣板(8或9),其操作即折叠或偏转纸张,纸板或类似物,包括矩形框架(81),其具有多对横向延伸的引导构件(84),所述导向构件 哪一张幻灯片。 横向于引导构件延伸的托架88在引导构件之间的空间中支撑多个片材控制构件89,使得控制构件能够在它们形成用于偏转片材的偏转表面的第一位置和第一位置之间移动, 第二位置,其作为用于定位待折叠的片材的止动构件。 第二位置可以根据片材的尺寸和折叠位置进行调节。 载体可滑动地安装在框架中,使得控制构件能够在第一和第二位置之间一致地移动。
    • 10. 发明申请
    • Orally bioavailable CCI-779 formulations
    • 口服生物可利用的CCI-779制剂
    • US20060183766A1
    • 2006-08-17
    • US11352726
    • 2006-02-13
    • Joseph BoniMuhammad AshrafEric Benjamin
    • Joseph BoniMuhammad AshrafEric Benjamin
    • A61K31/4745
    • A61K9/2095A61K9/146A61K9/2027A61K31/4745
    • A CCI-779 oral dosage form is provided in which, after oral administration to a subject, the CCI-779 has a whole blood peak concentration (Cmax) of 5.4±1.8 ng/mL and an area under the curve (AUC) of about 66±about 22 ng-hr/ml and the sirolimus has a Cmax of 18.7±9.6 ng/mL and an AUC of about 600±about 228 ng-hr/ml, for a 25 mg unit dose of CCI-779. Another CCI-779 oral dosage form is provided which, after oral administration thereof to a subject, the CCI-779 has a Cmax of 5.7±1.7 ng/mL and an AUC of about 60±about 20 ng-hr/ml and the sirolimus has a Cmax of 17.1±8.1 ng/mL and an AUC of about 548±about 187 ng-hr/ml in whole blood, for a 25 mg unit dose of CCI-779. Products containing these oral dosage forms, and methods of use thereof, are also described.
    • 提供CCI-779口服剂型,其中口服给予受试者后,CCI-779具有5.4±1.8ng / mL的全血峰浓度(C max)和面积 在约66±约22ng-hr / ml的曲线(AUC)下,西罗莫司的C max最大值为18.7±9.6ng / mL,AUC为约600±约228ng-hr / ml,用于25mg单位剂量的CCI-779。 提供了另一种CCI-779口服剂型,其在口服给予受试者后,CCI-779的C max≥5.7±1.7ng / mL,AUC为约60±20 ng-hr / ml,并且西罗莫司在全血中的C max最大值为17.1±8.1ng / mL,AUC为约548±约187ng-hr / ml,对于25mg单位剂量 的CCI-779。 还描述了含有这些口服剂型的产品及其使用方法。