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    • 1. 发明授权
    • Resin composition and metal laminate plate
    • 树脂组合物和金属层压板
    • US08173264B2
    • 2012-05-08
    • US12282602
    • 2006-03-17
    • Masao KawaguchiKiyomi ImagawaShuji TaharaEiji Ohtsubo
    • Masao KawaguchiKiyomi ImagawaShuji TaharaEiji Ohtsubo
    • B32B15/08
    • C08G73/1064B32B7/12B32B15/08B32B27/281B32B2307/306B32B2457/08C08G73/1039C08G73/124H05K1/0346Y10T428/31681
    • A resin composition comprises a polyimide resin composition or precursor thereof obtained from an acid dianhydride component containing a compound represented by the following Formula (1) and a diamine component containing a diamine compound represented by the following Formula (2), and a bismaleimide compound represented by the following Formula (3), wherein the diamine component contains a diamine compound (a) in which m in the Formula (2) represents an integer of 0 or 1 and a diamine component (b) in which m in the Formula (2) represents an integer of 2 to 6 in a molar ratio (a:b) of from 100:0 to 50:50, wherein, in the Formula (2), when m is 2 or more, each X may be independently the same or different, and represents O, SO2, S, CO, CH2, C(CH3)2, C(CF3)2 or a direct bond, wherein, in the Formula (3), n represents an integer of 0 to 6.
    • 树脂组合物包含由含有由下式(1)表示的化合物的酸二酐组分和含有由下式(2)表示的二胺化合物的二胺组分得到的聚酰亚胺树脂组合物或其前体,以及表示的二马来酰亚胺化合物 通过下式(3)表示,其中二胺成分含有式(2)中的m表示0或1的整数的二胺化合物(a)和式(2)中的m的二胺成分(b) )表示摩尔比(a:b)为100:0〜50:50的2〜6的整数,其中,在式(2)中,当m为2以上时,各X可以独立地相同 或不同的,并且表示O,SO 2,S,CO,CH 2,C(CH 3)2,C(CF 3)2或直接键,其中,在式(3)中,n表示0〜6的整数。
    • 9. 发明授权
    • Synthetic peptide, lung surfactant containing the same and remedy for
respiratory distress syndrome
    • 含有相同的合成肽,肺表面活性剂和呼吸窘迫综合征的补救
    • US5827825A
    • 1998-10-27
    • US652450
    • 1996-06-05
    • Tsunetomo TakeiEiji OhtsuboHirosi Ohkawa
    • Tsunetomo TakeiEiji OhtsuboHirosi Ohkawa
    • A61K38/00C07K14/785
    • C07K14/785A61K38/00
    • Synthetic peptides containing the following specific sequence: Xaa-Pro-Val-Xbb-Xcc-Lys-Arg-W (wherein Xaa is absent or represents Cys or Ser, Xbb represents His or Asn, Xcc represents Leu or Ile and W represents a hydrophobic peptide portion.), an intermediate for producing the peptide, a process for producing the peptide, a lung surfactant comprising the peptide and a lipid mixture and a remedy for respiratory distress syndrome containing the surfactant as the active ingredient. The peptide is easy to isolate and purify and suitable for mass production. As it is highly soluble in methanol and the like, it can readily be blended with a lipid mixture and is suited for the preparation of a lung surfactant. As the lung surfactant has a good supensibility and a potent surface activity, it is useful as a remedy for respiratory distress syndrome.
    • PCT No.PCT / JP94 / 02057 Sec。 371日期:1996年6月5日 102(e)日期1996年6月5日PCT 1994年12月7日PCT公布。 公开号WO95 / 15980 日期:1995年6月15日含有以下具体序列的合成肽:Xaa-Pro-Val-Xbb-Xcc-Lys-Arg-W(其中Xaa不存在或表示Cys或Ser,Xbb表示His或Asn,Xcc表示Leu或Ile W表示疏水性肽部分),生成肽的中间体,肽的制造方法,含有该肽的肺表面活性剂和脂质混合物,以及含有表面活性剂作为活性成分的呼吸窘迫综合症的治疗剂。 该肽易于分离和纯化,适合批量生产。 由于其高度可溶于甲醇等,因此可容易地与脂质混合物混合,并且适用于制备肺表面活性剂。 由于肺表面活性剂具有良好的显着性和强力的表面活性,因此作为呼吸窘迫综合征的治疗方法是有用的。