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    • 2. 发明授权
    • Molecular control of transgene segregation and its escape by a recoverable block of function (RBF) system
    • 转基因分离的分子控制及其可逆功能障碍(RBF)系统的逃逸
    • US06849776B1
    • 2005-02-01
    • US09617543
    • 2000-07-14
    • Viktor KuvshinovKimmo KoivuAnne KanervaEija Pehu
    • Viktor KuvshinovKimmo KoivuAnne KanervaEija Pehu
    • A01H1/02A01H1/04C12N15/31C12N15/55C12N15/82A01H5/00A01H1/00
    • C12N15/8251A01H1/02A01H1/04C12N15/8213C12N15/8241C12N15/8261C12N15/8263C12N15/8265C12N15/8287Y02A40/146
    • The invention is related to a method and a DNA construct for controlling transgene segregation in a sexually reproducing multicellular organism (SRMO), especially in such SRMOs which are susceptible of interbreeding with their cultured or wild-type relatives. The method and construct allows the farmer to reuse the transgenic crop without risk for escape of the transgene into the environment. The DNA construct is a recoverable block of function (RBF) system comprising at least one blocking construct (BC), and at least one means for recovering the blocked functions. The BC has a capacity of blocking at least one molecular or physiological function essential for the development and/or reproductive cycle of the SRMO. The BC is closely linked to the transgene of intereset (TGI). The blocked function is recoverable by an external treatment or intervention, which is optionally combined with one or more recovering constructs (RC). Different types of RBFs, including single, full, delayed, double, multiple and reversed delayed RBF are disclosed.
    • 本发明涉及一种用于控制性生殖多细胞生物体(SRMO)中转基因分离的方法和DNA构建体,特别是在易受其培养或野生型亲本杂交的SRMO中。 该方法和结构允许农民重新利用转基因作物,而不会将转基因逃离到环境中的风险。 DNA构建体是包含至少一个阻断构建体(BC)的可恢复功能块(RBF)系统,以及用于恢复阻断功能的至少一种装置。 BC具有阻断SRMO的发育和/或生殖循环所必需的至少一种分子或生理功能的能力。 BC与intereset(TGI)的转基因密切相关。 阻断的功能可以通过外部治疗或干预来恢复,其可选地与一种或多种恢复构建体(RC)组合。 公开了不同类型的RBF,包括单个,全部,延迟,双重,多个和反向延迟RBF。
    • 8. 发明申请
    • Transformation system for Camelina sativa
    • Camelina sativa的转化体系
    • US20120192318A1
    • 2012-07-26
    • US13385329
    • 2012-02-14
    • Viktor KuvshinovAnne KanervaKimmo KoivuEija Pehu
    • Viktor KuvshinovAnne KanervaKimmo KoivuEija Pehu
    • A01H5/00A01H5/10C12N5/04
    • C12N15/8205
    • In order to better aid consumers of prescription medicine and the like in efficient and rapid identification of the correct pill to be taken from among multiple containers, a novel group of articles of manufacture adapted for use with end-use prescription medicine containers at least includes a plurality of predetermined medicine purpose types corresponding to different types of medical or vitality purposes that underlying medicines are targeted to treat or address. Each article of manufacture is adapted to be coupled to an end-use, target prescription medicine container by an end-user or pharmacy function, and each article of manufacture at least includes an ideogram adapted to encourage a psychological association with, and identification of, the medicine expected to be placed in the target prescription medicine container to which the article of manufacture is adapted, and each article of manufacture is associated with a particular medicine purpose type.
    • 为了更好地帮助处方药等的消费者高效快速地鉴定从多个容器中取出的正确药丸,适于与终端使用处方药容器一起使用的新一批制造制品至少包括 多种预定的药物目的类型对应于基础药物被针对性地治疗或解决的不同类型的医疗或活力目的。 每个制品都适用于通过终端用户或药房功能与最终用途的目标处方药容器相连,并且每个制品至少包括适于鼓励心理关联的识别, 期望将药物放置在适于制造制品的目标处方药容器中,并且每个制品与特定药物目的类型相关联。