专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09510922B2 Systems and methods for treatment of sleep apnea 有权
标题翻译：用于治疗睡眠呼吸暂停的系统和方法
公开(公告)号：US09510922B2
公开(公告)日：2016-12-06
申请号：US13113946
申请日：2011-05-23
申请人： Edward M. Gillis , John H. Shadduck , Csaba Truckai , Andrew Poutiatine , Paul J. Buscemi
发明人： Edward M. Gillis , John H. Shadduck , Csaba Truckai , Andrew Poutiatine , Paul J. Buscemi
IPC分类号： A61F2/00 , A61F5/56
CPC分类号： A61F2/00 , A61F5/566 , A61F2210/0004
摘要： An implant for treating an obstructive airway disorder includes an elongate implant body configured for implanting in airway-interface tissue. At least a portion of the elongate body carries a light transmission material for permitting light transmission therein. Systems and methods of treating an airway disorder including implanting an implant in an airway-interface tissue are also provided.
摘要翻译：用于治疗阻塞性气道障碍的植入物包括构造成用于植入气道界面组织中的细长植入体。细长体的至少一部分携带用于允许光透射的透光材料。还提供了治疗气道障碍的系统和方法，包括将植入物植入气道界面组织中。

2. 发明申请

US20140251344A1 PARTIALLY ERODABLE SYSTEMS FOR TREATMENT OF OBSTRUCTIVE SLEEP APNEA 审中-公开
标题翻译：用于治疗阻塞性睡眠的部分可清除系统
公开(公告)号：US20140251344A1
公开(公告)日：2014-09-11
申请号：US14282943
申请日：2014-05-20
申请人： Edward M. GILLIS
发明人： Edward M. GILLIS
IPC分类号： A61F5/56
CPC分类号： A61F5/566 , A61F5/56
摘要： The invention relates to devices and methods for reforming tissue surrounding the airway of a subject suffering from obstructive sleep apnea so as to open the airway and alleviate the occurrence of apneic events. Devices comprise a combination of resiliently deformable material and bioerodible material. The deformable portion of the device has a preferred shape that corresponds to the desired final shape of the device once placed in an airway. In making a transplant-ready device, however, the deformable portion is placed into a deformed shape and constrained in that shape by the bioerodible material. After implantation, the device gradually assumes the preferred shape as the constraining bioerodible material erodes. As the device gradually reforms toward the preferred shape, it reforms the tissue into the therapeutically desirable configuration. The gradual nature of the shape change generally stabilizes the device in the tissue, and supports tissue reforming into a stable configuration.
摘要翻译：本发明涉及用于重组患有阻塞性睡眠呼吸暂停的受试者的气道周围的组织以便打开气道并减轻呼吸暂停事件的发生的装置和方法。装置包括可弹性变形材料和生物可腐蚀材料的组合。装置的可变形部分具有对应于一旦放置在气道中的装置的期望最终形状的优选形状。然而，在制造移植就绪装置中，可变形部分被放置成变形的形状并且被生物可腐蚀的材料限制在该形状中。植入后，随着约束生物可侵蚀材料侵蚀，装置逐渐呈现出优选的形状。随着装置逐渐改变为优选的形状，它将组织改造成治疗期望的构型。形状变化的逐渐性质通常使组织中的装置稳定，并支持组织重整成稳定的构型。

3. 发明授权

US08707960B2 Partially erodable systems for treatment of obstructive sleep apnea 失效
标题翻译：用于治疗阻塞性睡眠呼吸暂停的部分可侵蚀系统
公开(公告)号：US08707960B2
公开(公告)日：2014-04-29
申请号：US12937564
申请日：2009-05-11
申请人： Edward M. Gillis , Octavian Iancea
发明人： Edward M. Gillis , Octavian Iancea
IPC分类号： A61F5/56
CPC分类号： A61F5/56 , A61F5/566
摘要： A method of maintaining airway patency in an airway of a patient. The method includes the steps of implanting a device into airway-forming tissue without affixing the device to the tissue and permitting a bioerodable portion of the device to bioerode to apply a force to the airway-forming tissue to maintain airway patency. The invention also provides devices for practicing the method.
摘要翻译：维持患者气道通气通畅的方法。该方法包括以下步骤：将装置植入气道形成组织中，而不将装置固定在组织上，并允许装置的生物可蚀染部分进行生物代谢反应，以对气道形成组织施加力以保持气道通畅。本发明还提供了用于实施该方法的装置。

4. 发明申请

US20140007885A1 SYSTEMS AND METHODS FOR TREATMENT OF SLEEP APNEA 审中-公开
标题翻译：用于治疗睡眠APNEA的系统和方法
公开(公告)号：US20140007885A1
公开(公告)日：2014-01-09
申请号：US13935052
申请日：2013-07-03
申请人： Edward M. Gillis , Andrew Poutiatine , Paul J. Buscemi , John H. Shadduck
发明人： Edward M. Gillis , Andrew Poutiatine , Paul J. Buscemi , John H. Shadduck
IPC分类号： A61F5/56
CPC分类号： A61F5/566
摘要： Methods for treating sleep apnea. A method includes implanting at least first and second elongated implants in a tongue or soft palate of a patient, wherein each of the first and second implants is configured to have a first, expanded configuration and a second, contracted configuration, wherein implanting comprises implanting the first and second implants having their first, expanded configurations. The invention also provides systems for treating sleep apnea that can be used with the methods.
摘要翻译：睡眠呼吸暂停治疗方法一种方法包括将至少第一和第二细长植入物植入患者的舌或软腭中，其中第一和第二植入物中的每一个被配置为具有第一扩张构型和第二收缩构造，其中植入包括植入第一和第二植入物具有其第一，扩展的构型。本发明还提供了用于治疗可与该方法一起使用的睡眠呼吸暂停的系统。

5. 发明申请

US20140000631A1 SYSTEMS AND METHODS FOR TREATMENT OF SLEEP APNEA 有权
标题翻译：用于治疗睡眠APNEA的系统和方法
公开(公告)号：US20140000631A1
公开(公告)日：2014-01-02
申请号：US13539081
申请日：2012-06-29
申请人： Edward M. GILLIS , Csaba TRUCKAI , Paul J. Buscemi
发明人： Edward M. GILLIS , Csaba TRUCKAI , Paul J. Buscemi
IPC分类号： A61F5/56 , B23P11/00
CPC分类号： A61F5/566 , A61F2/00 , A61F2210/0004 , A61F2250/0018 , Y10T29/49826
摘要： Methods of maintaining airway patency in an airway of a patient. A method includes the steps of wrapping a bioerodable material at least partway around an axis to create a wound bioerodable implant, and coupling two points on the bioerodable material to each other. The invention also provides systems for maintaining airway patency in an airway of a patient that may be used with the methods.
摘要翻译：维持患者气道通气通畅的方法。一种方法包括以下步骤：将至少一部分可生物侵蚀的材料缠绕在轴线周围以产生缠绕的可生物侵蚀的植入物，并将可生物侵蚀的材料上的两个点彼此连接。本发明还提供了可以与该方法一起使用的用于维持患者气道中的气道通畅的系统。

6. 发明申请

US20130312767A1 Partially Erodable Systems for Treatment of Obstructive Sleep Apnea 失效
标题翻译：用于治疗阻塞性睡眠呼吸暂停的部分可侵蚀系统
公开(公告)号：US20130312767A1
公开(公告)日：2013-11-28
申请号：US13954589
申请日：2013-07-30
申请人： Edward M. Gillis
发明人： Edward M. Gillis
IPC分类号： A61F5/56
CPC分类号： A61F5/566 , A61F5/56
摘要： The invention relates to devices and methods for reforming tissue surrounding the airway of a subject suffering from obstructive sleep apnea so as to open the airway and alleviate the occurrence of apneic events. Devices comprise a combination of resiliently deformable material and bioerodible material. The deformable portion of the device has a preferred shape that corresponds to the desired final shape of the device once placed in an airway. In making a transplant-ready device, however, the deformable portion is placed into a deformed shape and constrained in that shape by the bioerodible material. After implantation, the device gradually assumes the preferred shape as the constraining bioerodible material erodes. As the device gradually reforms toward the preferred shape, it reforms the tissue into the therapeutically desirable configuration. The gradual nature of the shape change generally stabilizes the device in the tissue, and supports tissue reforming into a stable configuration.
摘要翻译：本发明涉及用于重组患有阻塞性睡眠呼吸暂停的受试者的气道周围的组织以便打开气道并减轻呼吸暂停事件的发生的装置和方法。装置包括可弹性变形材料和生物可腐蚀材料的组合。装置的可变形部分具有对应于一旦放置在气道中的装置的期望最终形状的优选形状。然而，在制造移植就绪装置中，可变形部分被放置成变形的形状并且被生物可腐蚀的材料限制在该形状中。植入后，随着约束生物可侵蚀材料侵蚀，装置逐渐呈现出优选的形状。随着装置逐渐改变为优选的形状，它将组织改造成治疗期望的构型。形状变化的逐渐性质通常使组织中的装置稳定，并支持组织重整成稳定的构型。

7. 发明申请

US20130098374A1 PARTIALLY ERODABLE SYSTEMS FOR TREATMENT OF OBSTRUCTIVE SLEEP APNEA 有权
公开(公告)号：US20130098374A1
公开(公告)日：2013-04-25
申请号：US13711537
申请日：2012-12-11
申请人： Edward M. Gillis , Octavian Iancea
发明人： Edward M. Gillis , Octavian Iancea
IPC分类号： A61F5/56
CPC分类号： A61F5/56 , A61F5/566
摘要： A method of maintaining airway patency in an airway of a patient which includes the steps of implanting a device into tissue adjacent an airway, the device having a bioerodable material wound around a resiliently deformable body to temporarily maintain the deformable body in a stretched, deformed state, and permitting the bioerodable material of the device to bioerode to apply a force to maintain airway patency. The invention also provides devices for practicing the method.

8. 发明申请

US20120239007A1 Implantable Devices and Methods for Treatment of Pain by Delivery of Fentanyl and Fentanyl Congeners 审中-公开
标题翻译：植入式装置和通过递送芬太尼和芬太尼同系物治疗疼痛的方法
公开(公告)号：US20120239007A1
公开(公告)日：2012-09-20
申请号：US13355217
申请日：2012-01-20
申请人： Edward M. Gillis , Barbara J. F. Laidlaw , John Culwell , James A. Filice , Peter Wickman , Andrew J. Poutiatine , John S. Dinka , Randolph M. Johnson , Felix Theeuwes
发明人： Edward M. Gillis , Barbara J. F. Laidlaw , John Culwell , James A. Filice , Peter Wickman , Andrew J. Poutiatine , John S. Dinka , Randolph M. Johnson , Felix Theeuwes
IPC分类号： A61M5/168
CPC分类号： A61F2/02 , A61F2250/0067 , A61K9/0004 , A61K9/0024 , A61K31/4468 , A61K31/4535 , A61K47/10 , A61K47/14 , A61K47/26 , A61M5/141 , A61M5/14276 , A61M5/1452 , A61M5/168 , A61M5/16804 , A61M5/16881 , A61M31/002 , A61M2005/14264 , Y02A50/401
摘要： The invention features devices and methods for treatment of pain. The drug delivery device is a drug delivery system adapted for whole implantation in a subject and to provide pain relief by delivery of fentanyl or a fentanyl congener (e.g., sufentanil) over a protracted period of time (e.g., at least 3 days or more than 3 days). The device comprises a housing defining a reservoir that contains a drug formulation, a pump operatively connected to the housing so as to facilitate movement of drug out of the reservoir and out of the device, and a thermal expansion element which defines a flow pathway comprising a thermal expansion channel to accommodate thermal expansion of formulation in the reservoir. The device can further comprise a valve positioned within the flow pathway so as to prevent movement of drug out of the reservoir prior to use.
摘要翻译：本发明的特征在于用于治疗疼痛的装置和方法。药物递送装置是适于整个植入受试者的药物递送系统，并通过在持续的时间段内输送芬太尼或芬太尼（例如舒芬太尼）来提供疼痛缓解（例如，至少3天或更多 3天）。该装置包括限定容纳药物制剂的储存器的壳体，可操作地连接到壳体的泵，以促进药物从储存器移出并离开装置;以及热膨胀元件，其限定流动通路，该热膨胀元件包括热膨胀通道，以适应储层中配方的热膨胀。该装置还可以包括位于流动通道内的阀，以便在使用之前防止药物从储存器中移动。

9. 发明申请

US20120017919A1 SYSTEMS AND METHODS FOR TREATMENT OF SLEEP APNEA 有权
标题翻译：用于治疗睡眠APNEA的系统和方法
公开(公告)号：US20120017919A1
公开(公告)日：2012-01-26
申请号：US13188385
申请日：2011-07-21
申请人： Edward M. Gillis , John H. Shadduck , Csaba Truckai , Andrew Poutiatine , Paul J. Buscemi
发明人： Edward M. Gillis , John H. Shadduck , Csaba Truckai , Andrew Poutiatine , Paul J. Buscemi
IPC分类号： A61F5/56
CPC分类号： A61F5/566
摘要： A method of treating an airway disorder includes placing an implant in a patient's tongue, wherein the implant has first and second end portions that attach to tissue, and a tensioned medial portion between the first and second ends. The medial portion is configured to apply a pressure of less than a predetermined amount. Device systems associated with such methods are also provided.
摘要翻译：治疗气道障碍的方法包括将植入物放置在患者舌头中，其中植入物具有连接到组织的第一和第二端部以及在第一和第二端之间的张紧的中间部分。内侧部分构造成施加小于预定量的压力。还提供了与这种方法相关联的设备系统。

10. 发明申请

US20110226263A1 SYSTEMS AND METHODS FOR TREATMENT OF SLEEP APNEA 有权
标题翻译：用于治疗睡眠APNEA的系统和方法
公开(公告)号：US20110226263A1
公开(公告)日：2011-09-22
申请号：US13053059
申请日：2011-03-21
申请人： Edward M. Gillis , Andrew Poutiatine , John H. Shadduck , Csaba Truckai
发明人： Edward M. Gillis , Andrew Poutiatine , John H. Shadduck , Csaba Truckai
IPC分类号： A61F5/56
CPC分类号： A61F5/566 , A61F2/00 , A61F5/56 , A61F2210/0004
摘要： A system for treating an airway disorder is provided with an implant body configured to conform to an airway-interface tissue site in a manner compatible with normal physiological function of the site. In some embodiments, the implant body includes an adjustment element configured to allow in-situ adjustment of the implant body between first and second tensioning forces applied to the site. Methods of using such systems are also provided.
摘要翻译：一种用于治疗气道障碍的系统设置有植入体，其构造成以与该部位的正常生理功能相适应的方式与气道界面组织部位一致。在一些实施例中，植入物主体包括调整元件，其被配置为允许植入物本体在施加到部位的第一和第二张力之间进行原位调整。还提供了使用这种系统的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式