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1. 发明公开

EP1210169A1 MIXING APPARATUS 有权
标题翻译：混合装置
公开(公告)号：EP1210169A1
公开(公告)日：2002-06-05
申请号：EP00958824.5
申请日：2000-09-07
申请人： Evans, Eric George
发明人： ASHCROFT, Peter Leonard , ARNOLD, David William
IPC分类号： B01F5/02 , B01F11/00
CPC分类号： B01F11/0074 , B01F5/0218 , B01F15/00487 , B01F15/0201 , B01F15/0243 , B01F2215/005
摘要： Apparatus for mixing liquid in a container, comprises a hollow sleeve member (10) for location in the lower regions of the container (2), a plurality of circumferentially spaced outlets (16) being provided in the upper regions of the sleeve member (10), pump means (38) for creating a reciprocating flow of liquid applied to the lower regions of the sleeve member (10), and, in the flow path of liquid from the pump means (38) to the sleeve member (10), a transducer mechanism (30) cooperating with the sleeve member (10) and subjected to the reciprocating flow of liquid such as to rotate the sleeve member (10) about its central longitudinal axis in dependence upon said reciprocating flow.
摘要翻译：用于在容器中混合液体的设备包括用于定位在容器（2）的下部区域中的中空套筒构件（10），在套筒构件（10）的上部区域中设置有多个沿周向间隔开的出口（16）），用于产生施加到套筒构件（10）下部区域的往复液流的泵装置（38），以及在从泵装置（38）到套筒构件（10）的液体流动路径中，与套筒构件（10）配合并经受液体的往复流动的换能器机构（30），以便根据所述往复流动使套筒构件（10）围绕其中心纵向轴线旋转。

2. 发明授权

EP1210169B1 MIXING APPARATUS 有权
公开(公告)号：EP1210169B1
公开(公告)日：2003-11-26
申请号：EP00958824.5
申请日：2000-09-07
申请人： Evans, Eric George
发明人： ASHCROFT, Peter Leonard , ARNOLD, David William
IPC分类号： B01F5/02 , B01F11/00
CPC分类号： B01F11/0074 , B01F5/0218 , B01F15/00487 , B01F15/0201 , B01F15/0243 , B01F2215/005
摘要： Apparatus for mixing liquid in a container, comprises a hollow sleeve member (10) for location in the lower regions of the container (2), a plurality of circumferentially spaced outlets (16) being provided in the upper regions of the sleeve member (10), pump means (38) for creating a reciprocating flow of liquid applied to the lower regions of the sleeve member (10), and, in the flow path of liquid from the pump means (38) to the sleeve member (10), a transducer mechanism (30) cooperating with the sleeve member (10) and subjected to the reciprocating flow of liquid such as to rotate the sleeve member (10) about its central longitudinal axis in dependence upon said reciprocating flow.

3. 发明专利

ES2211593T3 未知
公开(公告)号：ES2211593T3
公开(公告)日：2004-07-16
申请号：ES00958824
申请日：2000-09-07
申请人： EVANS ERIC GEORGE
发明人： ASHCROFT PETER LEONARD , ARNOLD DAVID WILLIAM
IPC分类号： B01F5/02 , B01F15/00 , B01F15/02 , B01F11/00
摘要： Apparatus for mixing liquid in a container, comprises a hollow sleeve member for location in the lower regions of the container, a plurality of circumferentially spaced outlets being provided in the upper regions of the sleeve member, pump means for creating a reciprocating flow of liquid applied to the lower regions of the sleeve member, and in the flow path of liquid from the pump means to the sleeve member, a transducer mechanism cooperating with the sleeve member and subjected to the reciprocating flow of liquid such as to rotate the sleeve member about its central longitudinal axis in dependence upon said reciprocating flow.

4. 发明专利

DE60006828T2 未知
公开(公告)号：DE60006828T2
公开(公告)日：2004-09-30
申请号：DE60006828
申请日：2000-09-07
申请人： EVANS ERIC GEORGE
发明人： ASHCROFT PETER LEONARD , ARNOLD DAVID WILLIAM
IPC分类号： B01F5/02 , B01F15/00 , B01F15/02 , B01F11/00
摘要： Apparatus for mixing liquid in a container, comprises a hollow sleeve member for location in the lower regions of the container, a plurality of circumferentially spaced outlets being provided in the upper regions of the sleeve member, pump means for creating a reciprocating flow of liquid applied to the lower regions of the sleeve member, and in the flow path of liquid from the pump means to the sleeve member, a transducer mechanism cooperating with the sleeve member and subjected to the reciprocating flow of liquid such as to rotate the sleeve member about its central longitudinal axis in dependence upon said reciprocating flow.

5. 发明专利

AT254955T 未知
公开(公告)号：AT254955T
公开(公告)日：2003-12-15
申请号：AT00958824
申请日：2000-09-07
申请人： EVANS ERIC GEORGE
发明人： ASHCROFT PETER LEONARD , ARNOLD DAVID WILLIAM
IPC分类号： B01F5/02 , B01F15/00 , B01F15/02 , B01F11/00
摘要： Apparatus for mixing liquid in a container, comprises a hollow sleeve member for location in the lower regions of the container, a plurality of circumferentially spaced outlets being provided in the upper regions of the sleeve member, pump means for creating a reciprocating flow of liquid applied to the lower regions of the sleeve member, and in the flow path of liquid from the pump means to the sleeve member, a transducer mechanism cooperating with the sleeve member and subjected to the reciprocating flow of liquid such as to rotate the sleeve member about its central longitudinal axis in dependence upon said reciprocating flow.

6. 发明专利

IL255729D0 Methods of predicting pathogenicity of genetic sequence variants 未知
公开(公告)号：IL255729D0
公开(公告)日：2018-01-31
申请号：IL25572917
申请日：2017-11-16
申请人： COUNSYL INC , HAQUE IMRAN SAEEDUL , EVANS ERIC ANDREW , VIKRAM SHARAD MANDYAM , RASMUSSEN MATTHEW DAVID
发明人： HAQUE IMRAN SAEEDUL , EVANS ERIC ANDREW , VIKRAM SHARAD MANDYAM , RASMUSSEN MATTHEW DAVID
IPC分类号： G06F20060101
摘要： Recent developments in cost-effective DNA sequencing allows for individualized genomic screening of a subject for genetic sequence variants. Training a pathogenicity prediction model using semi-supervised training methods produces a better model for predicting the pathogenicity of a test genetic sequence variant. Provided herein are methods for predicting the pathogenicity of a test genetic sequence variant by utilizing a training data set comprising labeled benign genetic sequence variants unlabeled genetic sequence variants, the unlabeled genetic sequence variants comprising a mixture of benign genetic sequence variants and pathogenic genetic sequence variants. The genetic sequences are annotated with one or more features and a machine learning model is trained in a semi-supervised process based on the training data. The test genetic sequence is then annotated using the one or more features and the probability that the test genetic sequence variant is pathogenic is predicted based on the trained machine learning model.

7. 发明专利

DE60006828D1 未知
公开(公告)号：DE60006828D1
公开(公告)日：2004-01-08
申请号：DE60006828
申请日：2000-09-07
申请人： EVANS ERIC GEORGE
发明人： ASHCROFT PETER LEONARD , ARNOLD DAVID WILLIAM
IPC分类号： B01F5/02 , B01F15/00 , B01F15/02 , B01F11/00
摘要： Apparatus for mixing liquid in a container, comprises a hollow sleeve member for location in the lower regions of the container, a plurality of circumferentially spaced outlets being provided in the upper regions of the sleeve member, pump means for creating a reciprocating flow of liquid applied to the lower regions of the sleeve member, and in the flow path of liquid from the pump means to the sleeve member, a transducer mechanism cooperating with the sleeve member and subjected to the reciprocating flow of liquid such as to rotate the sleeve member about its central longitudinal axis in dependence upon said reciprocating flow.

8. 发明专利

CA2383997A1 MIXING APPARATUS 未知
公开(公告)号：CA2383997A1
公开(公告)日：2001-03-15
申请号：CA2383997
申请日：2000-09-07
申请人： EVANS ERIC GEORGE
发明人： ARNOLD DAVID WILLIAM , ASHCROFT PETER LEONARD
IPC分类号： B01F5/02 , B01F15/00 , B01F15/02 , B01F11/00
摘要： Apparatus for mixing liquid in a container, comprises a hollow sleeve member (10) for location in the lower regions of the container (2), a plurality of circumferentially spaced outlets (16) being provided in the upper regions of the sleeve member (10), pump means (38) for creating a reciprocating flow of liquid applied to the lower regions of the sleeve member (10), and, in the flow path of liquid from the pump means (38) to the sleeve member (10), a transducer mechanism (30) cooperating with the sleeve member (10) and subjected to the reciprocating flow of liquid such as to rotate the sleeve member (10) about its central longitudinal axis in dependence upon said reciprocating flow.

9. 发明申请

WO1982002743A1 FLUID-PESSURE OPERATED MOTORS 审中-公开
标题翻译：流体动力电动机
公开(公告)号：WO1982002743A1
公开(公告)日：1982-08-19
申请号：PCT/GB1982000039
申请日：1982-02-12
申请人： KINGDOM ENG CO LTD , EVANS ERIC GEORGE , MASON FRANK WILLIAM , HUDSON ANTHONY JOHN
发明人： KINGDOM ENG CO LTD
IPC分类号： F01L25/06
CPC分类号： F01B11/02 , F01L25/063 , F04B49/12
摘要： An air motor comprising a piston and cylinder unit and control means mounted wholly within a housing secured to the unit. The housing comprises two parts (11, 12) at the ends of the cylinder (10) and a manifold assembly (28, 30) extending alongside the cylinder (10) and these end parts. The control means comprises a changeover valve (25) in the manifold assembly and two control valves (26, 27) in the respective end parts (11, 12) which are operated by mechanical actuators (K 1, K2) engaged by the piston (13) when it reaches the ends of its stroke and thereupon cause the changeover valve to change over the supply of compressed air from an inlet (60) in the manifold assembly, from one end of the cylinder to the other thereby to reverse the movement of the piston so that the piston reciprocates in the cylinder. The piston may comprise two parts (51, 52) which are adjustable to vary its effective length and hence its strocke.
摘要翻译：一种包括活塞和气缸单元的气动马达和完全安装在固定到该单元的壳体内的控制装置。壳体在气缸（10）的端部处包括两个部分（11,12）和沿气缸（10）和这些端部部分延伸的歧管组件（28,30）。控制装置包括歧管组件中的转换阀（25）和在各个端部（11,12）中的两个由活塞接合的机械致动器（K 1，K 2）操作的控制阀（26,27） 13）当其到达其行程的端部并且随后使得切换阀从压缩机组件中的入口（60）从气缸的一端到另一端的压缩空气的供给转换时，活塞使得活塞在气缸中往复运动。活塞可以包括两个部分（51,52），其可调节以改变其有效长度并因此改变其频率。

10. 发明申请

WO2014015084A2 SYSTEM AND METHODS FOR DETECTING GENETIC VARIATION 审中-公开
标题翻译：用于检测遗传变异的系统和方法
公开(公告)号：WO2014015084A2
公开(公告)日：2014-01-23
申请号：PCT/US2013/050965
申请日：2013-07-17
申请人： COUNSYL, INC. , RICHARDS, Hunter , EVANS, Eric , SRINIVASAN, Balaji , SRINIVASAN, Subramaniam , SHAH, Abhik , PATTERSON, A., Scott , CHU, Clement
发明人： RICHARDS, Hunter , EVANS, Eric , SRINIVASAN, Balaji , SRINIVASAN, Subramaniam , SHAH, Abhik , PATTERSON, A., Scott , CHU, Clement
IPC分类号： C40B50/18 , C40B20/00
CPC分类号： C12Q1/6869 , C12Q1/6827 , C12Q1/6874 , C12Q2525/155 , C12Q2525/161 , C12Q2537/143 , C12Q2563/179 , C12Q2565/543 , C12Q2535/122 , C12Q2565/514
摘要： The invention provides methods, apparatuses, and compositions for high- throughput amplification sequencing of specific target sequences in one or more samples. In some aspects, barcode-tagged polynucleotides are sequenced simultaneously and sample sources are identified on the basis of barcode sequences. In some aspects, sequencing data are used to determine one or more genotypes at one or more loci comprising a causal genetic variant. In some aspects, systems and methods of detecting genetic variation are provided.
摘要翻译：本发明提供了用于一个或多个样品中特定靶序列的高通量扩增测序的方法，装置和组合物。在一些方面，条形码标记的多核苷酸被同时测序，并且根据条形码序列鉴定样品来源。在一些方面，测序数据用于确定包含致病性遗传变体的一个或多个基因座处的一种或多种基因型。在一些方面，提供了检测遗传变异的系统和方法。

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