专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2008103126A1 NOVEL COMBINATION OF COMPOUNDS TO BE USED IN THE TREATMENT OF AIRWAY DISEASES, ESPECIALLY CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) AND ASTHMA 审中-公开
标题翻译：用于治疗气道疾病，特别是慢性阻塞性肺疾病（COPD）和哮喘的化合物的新组合
公开(公告)号：WO2008103126A1
公开(公告)日：2008-08-28
申请号：PCT/SE2008/050204
申请日：2008-02-21
申请人： ASTRAZENECA AB , ERIKSSON, Tomas , HANSSON, Johan , MENSONIDES-HARSEMA, Marguerite , MO, John
发明人： ERIKSSON, Tomas , HANSSON, Johan , MENSONIDES-HARSEMA, Marguerite , MO, John
IPC分类号： A61K31/438 , A61K31/569 , A61P11/06 , A61P11/08 , C07D471/10 , C07D491/107
CPC分类号： A61K31/438 , A61K31/569 , C07D471/10 , C07D491/10
摘要： The present invention provides a pharmaceutical product comprising, in combination of, (a) a (therapeutically effective) dose of a first active ingredient, which is a compound of formula (I) or a pharmaceutically acceptable salt thereof; and (b) a (therapeutically effective) dose of a second active ingredient, which is a glucocorticoid receptor agonist; and optionally, (c) a (therapeutically effective) dose of a third active ingredient, which is a β 2 -agonist. The invention further relates to pharmaceutical compositions comprising said combination and to methods of treating treatment of airway diseases, especially chronic obstructive pulmonary disease (COPD) and asthma in mammals by administrating said combination. The invention further relates to a kit comprising the combination and use of said kit in treatment of airway diseases such as COPD and asthma.
摘要翻译：本发明提供了包含（a）（治疗有效）剂量的第一活性成分（其为式（I）的化合物或其药学上可接受的盐）的药物产品，和（b）（治疗有效的）剂量的第二活性成分，其是糖皮质激素受体激动剂; 和（c）（治疗有效的）剂量的第三活性成分，其为β2激动剂。本发明还涉及包含所述组合的药物组合物和通过施用所述组合来治疗气道疾病，特别是慢性阻塞性肺疾病（COPD）和哺乳动物哮喘的治疗方法。本发明还涉及包含所述试剂盒在治疗气道疾病如COPD和哮喘中的组合和用途的试剂盒。

2. 发明申请

WO2007093217A1 AN OVERVOLTAGE PROTECTOR CIRCUIT AND A DETECTOR CIRCUIT FOR SUPERVISING SUCH A PROTECTOR CIRCUIT 审中-公开
标题翻译：用于监控这种保护电路的过电压保护器电路和检测器电路
公开(公告)号：WO2007093217A1
公开(公告)日：2007-08-23
申请号：PCT/EP2006/060019
申请日：2006-02-16
申请人： Telefonaktiebolaget LM Ericsson (publ) , ERIKSSON, Tomas
发明人： ERIKSSON, Tomas
IPC分类号： H02H3/04 , H02H9/04 , H02H9/06
CPC分类号： H02H3/048 , H02H9/06
摘要： An overvoltage protector circuit (14) for telecommunication equipments (12), said protector circuit including a gas discharge tube (17) connected to a communication line (11) for passing any harmful surge currents appearing in the line to ground (15). A degradation detector circuit (18) is arranged to detect any degradation of the gas discharge tube (17), the detector circuit comprises a reference gas discharge tube (19) with a higher breakdown voltage than the supervised gas discharge tube (17) and an alarm circuit loop (20) connected to an alarm system (30). Said alarm system is arranged to detect when current is breaking through the reference gas discharge tube (19) and to initiate a degradation alarm.
摘要翻译：一种用于电信设备（12）的过电压保护器电路（14），所述保护器电路包括连接到通信线路（11）的气体放电管（17），用于将出现在地线（15）中的任何有害的浪涌电流传递。降级检测器电路（18）被布置成检测气体放电管（17）的任何劣化，检测器电路包括具有比监督气体放电管（17）更高的击穿电压的参考气体放电管（19）和报警电路回路（20）连接到报警系统（30）。所述报警系统被布置成检测当前的电流是否穿过参考气体放电管（19）并发起降级报警。

3. 发明申请

WO0159757A3 METHOD AND APPARATUS FOR COMPRESSION OF SPEECH ENCODED PARAMETERS 审中-公开
标题翻译：用于压缩语音编码参数的方法和装置
公开(公告)号：WO0159757A3
公开(公告)日：2002-11-07
申请号：PCT/EP0101183
申请日：2001-02-05
申请人： ERICSSON TELEFON AB L M , MEKURIA FISSEHA , DELLIEN NIDZARA , ERIKSSON TOMAS
发明人： MEKURIA FISSEHA , DELLIEN NIDZARA , ERIKSSON TOMAS
IPC分类号： G10L19/00 , H04M1/65 , H03M7/30
CPC分类号： G10L19/00 , H04M1/6505
摘要： A communication apparatus having a speech encoded and speech decoder able to retrieve and store voice messages in memory is described. The messages are stored in the memory according to a more compressed message format than the speech-encoding format of the speech encoder. The apparatus includes a frame interpolation block for decompressing stored messages and thereby creating a signal in the speech-encoding format. A frame-decimation block compresses a speech-encoded signal, thereby allowing a corresponding voice message to be stored in the memory in the message format. A statistical analysis is performed to determine inter-frame redundancy of parameters of the encoded signal. A portion of those parameters having relatively high inter-frame redundancy are compressed using a lossless compression algorithm, while a portion of those parameters having relatively low inter-frame redundancy are compressed using a lossy compression algorithm. Other parameters are not compressed according to pre-determined criteria irrespective of their inter-frame redundancy.
摘要翻译：描述了具有能够在存储器中检索和存储语音消息的语音编码和语音解码器的通信装置。消息根据比语音编码器的语音编码格式更加压缩的消息格式存储在存储器中。该装置包括用于对存储的消息进行解压缩并由此创建语音编码格式的信号的帧内插块。帧抽取块压缩语音编码信号，从而允许相应的语音消息以消息格式存储在存储器中。执行统计分析以确定编码信号的参数的帧间冗余。使用无损压缩算法压缩具有相对较高的帧间冗余的那些参数的一部分，而使用有损压缩算法来压缩具有相对低的帧间冗余的那些参数的一部分。不考虑其帧间冗余，其他参数也不会根据预先确定的标准进行压缩。

4. 发明申请

WO2002076457A1 NOVEL AMIDES, PREPARATION AND THERAPEUTIC USE AS MODULATORS OF CCR-RECEPTOR ACTIVITY 审中-公开
标题翻译：作为CCR-受体活性的调节剂的新辅剂，制剂和治疗用途
公开(公告)号：WO2002076457A1
公开(公告)日：2002-10-03
申请号：PCT/SE2002/000541
申请日：2002-03-19
申请人： ASTRAZENECA AB , ERIKSSON, Tomas , LAWITZ, Karolina
发明人： ERIKSSON, Tomas , LAWITZ, Karolina
IPC分类号： A61K31/4468
CPC分类号： C07D401/12 , C07D401/14
摘要： The invention provides compounds of general formula (I), wherein R 1 , X, Y, n, R 2 , Z 1 , Z 2 , A 1 , A 2 , Q, R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , t and R 16 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
摘要翻译：本发明提供通式（I）的化合物，其中R 1，X，Y，n，R 2，Z 1，Z 2，A 1，A 2， R 3，R 4，R 5，R 6，R 7，R 8，t和R 16如本说明书中所定义，其制备方法，药物组合物包含它们及其在治疗中的用途。

5. 发明申请

WO1998012219A1 METHIONINE, PENICILLAMINE AND CYSTEINE-ANALOGUE CONTAINING PEPTIDES HAVING IMMUNOMODULATING ACTIVITY 审中-公开
标题翻译：含有免疫调节活性的甲硫氨酸，苯胺胺和CYSTEINE-ANALOGUE含有肽
公开(公告)号：WO1998012219A1
公开(公告)日：1998-03-26
申请号：PCT/SE1997001554
申请日：1997-09-15
申请人： ASTRA AKTIEBOLAG , BERGSTRAND, Håkan , ERIKSSON, Tomas , LINDVALL, Magnus , SÄRNSTRAND, Bengt
发明人： ASTRA AKTIEBOLAG
IPC分类号： C07K07/06
CPC分类号： C07K7/06 , A61K38/00
摘要： Physiologically active peptides of 8ormula (I): A-R1-R2-R3-(R4)x-B, wherein each variable has the meaning mentioned in the description at least one of R1, R2 and R3 being R8 and at most one of R1, R2 and R3 being cysteine; and R8 is an amino acid residue of formula (II) or formula (III), wherein each variable has the meaning described in the description, the entire peptide sequence containing 3 to 30 amino acid residues; or a homo- or heterodimers thereof. These peptides are absorbable by the epithelial cell lining in a mammal resulting in a modulated immune response and thereby a therapeutic effect against disease.
摘要翻译：（I）：A-R1-R2-R3-（R4）xB的生理活性肽，其中每个变量具有说明书中提及的含义，R 1，R 2和R 3中的至少一个为R 8，并且至少一个R 1， R2和R3是半胱氨酸; 并且R 8是式（II）或式（III）的氨基酸残基，其中每个变量具有描述中描述的含义，整个含有3至30个氨基酸残基的肽序列; 或其同二聚体或异二聚体。这些肽可以通过哺乳动物的上皮细胞衬里吸收，导致调节的免疫应答，从而对抗疾病的治疗效果。

6. 发明申请

WO2010129157A1 ISOTOPE PRODUCTION SYSTEM AND CYCLOTRON HAVING A MAGNET YOKE WITH A PUMP ACCEPTANCE CAVITY 审中-公开
标题翻译：同位素生产系统和带有泵接收孔的磁铁的循环
公开(公告)号：WO2010129157A1
公开(公告)日：2010-11-11
申请号：PCT/US2010/031394
申请日：2010-04-16
申请人： GENERAL ELECTRIC COMPANY , NORLING, Janas , ERIKSSON, Tomas
发明人： NORLING, Janas , ERIKSSON, Tomas
IPC分类号： H05H13/00 , H05H7/00 , H05H13/02 , H05H7/14
CPC分类号： H05H13/005 , H05H7/00 , H05H7/14 , H05H13/02
摘要： A cyclotron that includes a magnet assembly to produce a magnetic field to direct charged particles along a desired path. The cyclotron also includes a magnet yoke that has a yoke body that surrounds an acceleration chamber. The magnet assembly is located in the yoke body. The yoke body forms a pump acceptance (PA) cavity that is fluidicly coupled to the acceleration chamber. The cyclotron also includes a vacuum pump that is configured to introduce a vacuum into the acceleration chamber. The vacuum pump is positioned in the PA cavity.
摘要翻译：回旋加速器，其包括磁体组件以产生磁场，以沿着期望的路径引导带电粒子。回旋加速器还包括具有围绕加速室的轭体的磁轭。磁体组件位于轭体中。轭体形成流体耦合到加速室的泵接受（PA）腔。回旋加速器还包括被构造成将真空引入加速室的真空泵。真空泵定位在PA腔中。

7. 发明申请

WO2010129103A1 ISOTOPE PRODUCTION SYSTEM AND CYCLOTRON HAVING REDUCED MAGNETIC STRAY FIELDS 审中-公开
标题翻译：同位素生产系统和具有减少磁场的循环
公开(公告)号：WO2010129103A1
公开(公告)日：2010-11-11
申请号：PCT/US2010/028573
申请日：2010-03-25
申请人： GENERAL ELECTRIC COMPANY , NORLING, Jonas , ERIKSSON, Tomas
发明人： NORLING, Jonas , ERIKSSON, Tomas
IPC分类号： H05H13/00
CPC分类号： H05H13/00 , Y10T29/49002
摘要： A cyclotron that includes a magnet yoke that has a yoke body that surrounds an acceleration chamber and a magnet assembly. The magnet assembly is configured to produce magnetic fields to direct charged particles along a desired path. The magnet assembly is located in the acceleration chamber. The magnetic fields propagate through the acceleration chamber and within the magnet yoke. A portion of the magnetic fields escape outside of the magnet yoke as stray fields. The magnet yoke is dimensioned such that the stray fields do not exceed 5 Gauss at a distance of 1 meter from an exterior boundary.
摘要翻译：回旋加速器包括具有包围加速室的轭体和磁体组件的磁轭。磁体组件被配置为产生磁场以沿着期望的路径引导带电粒子。磁体组件位于加速室中。磁场传播通过加速室和磁轭内。一部分磁场作为杂散场逃逸到磁轭外。磁轭的尺寸设计使得杂散场与外部边界距离1米的距离不超过5高斯。

8. 发明申请

WO2010008341A1 A COMBINATION OF (A) GLUCOCORTICOID RECEPTOR MODULATOR AND (B) A MUSCARINIC ANTAGONIST 审中-公开
标题翻译：（A）葡萄糖胆碱受体调节剂的组合和（B）肌肉酸碱调节剂
公开(公告)号：WO2010008341A1
公开(公告)日：2010-01-21
申请号：PCT/SE2009/050900
申请日：2009-07-15
申请人： ASTRAZENECA AB , ERIKSSON, Tomas , HANSSON, Thomas
发明人： ERIKSSON, Tomas , HANSSON, Thomas
IPC分类号： A61K31/416 , A61K31/421 , A61K31/46 , A61P11/00 , A61P11/06
CPC分类号： A61K45/06 , A61K9/0073 , A61K31/416 , A61K31/421 , A61K31/46
摘要： The present invention relates to a combination of (a) a glucocorticoid receptor modulator and (b) a muscarinic antagonist. The invention further relates to pharmaceutical compositions comprising said combination and to methods of treatment of airway diseases, such as chronic obstructive pulmonary disease (COPD) and asthma in mammals by administrating said combination. The invention further relates to a kit comprising the combination and use of said kit in treatment of airway diseases.
摘要翻译：本发明涉及（a）糖皮质激素受体调节剂和（b）毒蕈碱拮抗剂的组合。本发明还涉及包含所述组合的药物组合物和通过施用所述组合治疗气道疾病如慢性阻塞性肺病（COPD）和哺乳动物哮喘的方法。本发明还涉及包含所述试剂盒在治疗气道疾病中的组合和用途的试剂盒。

9. 发明申请

WO2009142589A1 COMBINATION OF (A) GLUCOCORTICOID RECEPTOR MODULATOR AND (B) A MUSCARINIC ANTAGONIST 审中-公开
标题翻译：（A）葡萄糖激素受体调节剂的组合和（B）一种肌钙蛋白
公开(公告)号：WO2009142589A1
公开(公告)日：2009-11-26
申请号：PCT/SE2009/050564
申请日：2009-05-19
申请人： ASTRAZENECA AB , BAYER SCHERING PHARMA AG , ERIKSSON, Tomas , HANSSON, Thomas
发明人： ERIKSSON, Tomas , HANSSON, Thomas
IPC分类号： A61K31/416 , A61P11/00
CPC分类号： A61K45/06 , A61K31/416 , A61K2300/00
摘要： The present invention relates to a combination of (a) a glucocorticoid receptor modulator and (b) a muscarinic antagonist. The invention further relates to pharmaceutical compositions comprising said combination and to methods of treatment of airway diseases, such as chronic obstructive pulmonary disease (COPD) and asthma in mammals by administrating said combination. The invention also relates to a kit comprising the combination and use of said kit in treatment of airway diseases.
摘要翻译：本发明涉及（a）糖皮质激素受体调节剂和（b）毒蕈碱拮抗剂的组合。本发明还涉及包含所述组合的药物组合物和通过施用所述组合治疗气道疾病如慢性阻塞性肺病（COPD）和哺乳动物哮喘的方法。本发明还涉及包含所述试剂盒在治疗气道疾病中的组合和用途的试剂盒。

10. 发明申请

WO2003051839A1 NOVEL COMPOUNDS 审中-公开
标题翻译：新型化合物
公开(公告)号：WO2003051839A1
公开(公告)日：2003-06-26
申请号：PCT/SE2002/002304
申请日：2002-12-11
申请人： ASTRAZENECA AB , ERIKSSON, Tomas , NOORI, Ghazi
发明人： ERIKSSON, Tomas , NOORI, Ghazi
IPC分类号： C07D211/58
CPC分类号： C07D211/58
摘要： The invention provides compounds of formula[Chemical formula should be inserted here. Please see paper copy]wherein m, R 1 and R 2 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
摘要翻译：本发明提供了式[化学式]的化合物。请参见纸质文件]其中m，R> 1和R 2如说明书中所定义，其制备方法，含有它们的药物组合物及其在治疗中的用途。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式