专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5486459A Biologically relevant methods for the rapid determination of sterility 失效
标题翻译：用于快速测定不育的生物相关方法
公开(公告)号：US5486459A
公开(公告)日：1996-01-23
申请号：US380195
申请日：1995-01-30
申请人： Jeffrey C. Burnham , George J. Hageage , Douglas Jambard-Sweet , Judy Hendricks
发明人： Jeffrey C. Burnham , George J. Hageage , Douglas Jambard-Sweet , Judy Hendricks
IPC分类号： C12M1/12 , C12M1/34 , C12M1/40 , C12Q1/22 , G01N21/00
CPC分类号： C12Q1/22 , Y10S435/81 , Y10S435/832 , Y10S435/842 , Y10S435/92
摘要： The invention is directed to biological processes and apparatus for determining the efficacy of a sterilization cycle based upon the recovery of activity of interactive enzyme systems comprising enzymes, coenzymes, catalysts, cofactors, substrates or any other necessary reagents. The invention provides a vital process for expediting sterility verification before utilization of the articles thought to be sterilized. The invention involves the rapid detection of any surviving interactive enzymatic activity which directly relates to the probability of any biological spores surviving in a test sample. An absence of a change indicates that the sterilization process had inactivated the enzyme system thereby preventing the interactive reaction from taking place which is a rapid equivalent to directly detecting the survivability of bacterial spores in a similar test. The methods and apparatus of the invention are useful in the health care industry such as in hospitals, laboratories, and research institutions, in food and environmental technology, and in all technologies which utilize sterilization in manufacturing, production or waste disposal.
摘要翻译：本发明涉及用于基于包含酶，辅酶，催化剂，辅因子，底物或任何其它必需试剂的相互作用的酶系统的活性的恢复来确定灭菌循环的功效的生物过程和装置。本发明提供了在使用被认为消毒的物品之前加速无菌验证的重要过程。本发明涉及快速检测任何存活的互动酶活性，其直接涉及在测试样品中存活的任何生物孢子的概率。没有变化表明灭菌过程已经使酶系统失活，从而防止相互作用反应的发生，其在类似试验中快速等同于直接检测细菌孢子的生存性。本发明的方法和装置在医疗保健行业如医院，实验室和研究机构，食品和环境技术以及在制造，生产或废物处理中利用灭菌的所有技术中都是有用的。

IPRDB

热门服务

关于我们

友情链接

联系方式