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1. 发明授权

US07655040B2 Cardiac valve annulus reduction system 有权
标题翻译：心脏瓣膜减压系统
公开(公告)号：US07655040B2
公开(公告)日：2010-02-02
申请号：US10531819
申请日：2004-11-12
申请人： Nareak Douk , Nasser Rafiee , Eliot Bloom , Douglas A. Fogg , Rany Huynh , David D. Barone
发明人： Nareak Douk , Nasser Rafiee , Eliot Bloom , Douglas A. Fogg , Rany Huynh , David D. Barone
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61B17/00234 , A61B17/0401 , A61B2017/00243 , A61B2017/00783 , A61B2017/0414 , A61B2017/0496 , A61B2017/06052 , A61B2017/06176 , A61F2002/30545 , A61F2220/0016 , A61F2250/001
摘要： A catheter-based, annulus reduction device and system for cardiac valve repair and method of using the same. The system is usable for treating mitral valve regurgitation and comprises a catheter, a reduction ring carried within the catheter, the reduction ring including a plurality of exit ports formed in a side wall of the reduction ring and filament received in the reduction ring. The filament includes a plurality of radially extendible barbs corresponding to the sidewall openings. The reduction ring carrying the filament is deployed adjacent a mitral valve annulus and the filament is translated relative to the reduction ring to deploy the barbs through the exit ports and into the annulus and to further translate the reduction ring with deployed barbs to reshape the annulus.
摘要翻译：一种基于导管的减压装置和心脏瓣膜修复系统及其使用方法。该系统可用于治疗二尖瓣反流，并且包括导管，在导管内承载的还原环，所述还原环包括形成在所述还原环的侧壁中的多个出口和容纳在所述还原环中的细丝。灯丝包括对应于侧壁开口的多个可径向延伸的倒钩。承载细丝的还原环被布置在二尖瓣环附近，并且细丝相对于还原环平移，以将倒钩布置在出口端口并进入环形空间中，并且进一步将还原环用展开的倒钩重新平整以环形环。

2. 发明授权

US07131978B2 Surgical suturing instrument and method of use 有权
公开(公告)号：US07131978B2
公开(公告)日：2006-11-07
申请号：US10441652
申请日：2003-05-19
申请人： Gregory E. Sancoff , Joseph A. DiCarlo , Frederic P. Field , Douglas A. Fogg , Charles H. Pugsley, Jr.
发明人： Gregory E. Sancoff , Joseph A. DiCarlo , Frederic P. Field , Douglas A. Fogg , Charles H. Pugsley, Jr.
IPC分类号： A61B17/04
CPC分类号： A61B17/0644 , A61B17/0469 , A61B17/0483 , A61B17/064 , A61B17/068 , A61B17/2909 , A61B2017/00004 , A61B2017/00783 , A61B2017/00827 , A61B2017/06171 , A61B2017/0646 , A61B2017/2929 , A61F2/0063
摘要： A device is disclosed for introducing a flexible elongated element through at least two portions of a subject. In an embodiment, the device includes a proximal end and a distal end, as well as an advancement unit for longitudinally advancing the flexible elongated element toward the distal end such that a proximal end of the elongated element may pass from the distal end of said device with sufficient force to pass through the portions of the subject. The device also includes a securing unit for variably adjusting a securing force applied by the flexible elongated element to secure together the portions of the subject.

3. 发明授权

US07037315B2 Surgical suturing instrument and method of use 有权
标题翻译：手术缝合仪及其使用方法
公开(公告)号：US07037315B2
公开(公告)日：2006-05-02
申请号：US10243556
申请日：2002-09-13
申请人： Gregory E. Sancoff , Frederic P. Field , Douglas A. Fogg , Joseph A. DiCarlo
发明人： Gregory E. Sancoff , Frederic P. Field , Douglas A. Fogg , Joseph A. DiCarlo
IPC分类号： A61B17/04
CPC分类号： A61B17/064 , A61B17/0469 , A61B17/0483 , A61B17/068 , A61B2017/00004 , A61B2017/00827 , A61B2017/0498 , A61B2017/0646 , A61B2017/2929
摘要： A device is disclosed for introducing a flexible elongated element through at least two portions of a subject. In an embodiment, the device includes a proximal end and a distal end, as well as an advancement unit for longitudinally advancing the flexible elongated element toward the distal end such that a distal end of the elongated element may pass from the distal end of said device with sufficient force to pass through the portions of the subject. The device also includes a securing unit for variably adjusting a securing force applied by the flexible elongated element to secure together the portions of the subject.
摘要翻译：公开了用于通过受试者的至少两个部分引入柔性细长元件的装置。在一个实施例中，该装置包括近端和远端，以及用于将柔性细长元件朝向远端纵向前进的前进单元，使得细长元件的远端可以从所述装置的远端具有足够的力穿过受试者的部分。该装置还包括固定单元，用于可变地调节由柔性细长元件施加的固定力，以将主体的部分固定在一起。

4. 发明授权

US06511489B2 Surgical suturing instrument and method of use 失效
标题翻译：手术缝合仪及其使用方法
公开(公告)号：US06511489B2
公开(公告)日：2003-01-28
申请号：US10082510
申请日：2001-10-19
申请人： Frederic P. Field , Douglas A. Fogg , Gregory E. Sancoff
发明人： Frederic P. Field , Douglas A. Fogg , Gregory E. Sancoff
IPC分类号： A61B1704
CPC分类号： A61B17/0682 , A61B17/0467 , A61B17/0469 , A61B17/064 , A61B17/0644 , A61B17/068 , A61B2017/0649
摘要： A device is disclosed for introducing a flexible elongated element through at least two portions of a subject. In a preferred embodiment, the device includes a proximal end and a distal end, and an advancement unit for longitudinally advancing the flexible elongated element toward the distal end of the device such that a proximal end of the elongated element may exit from the distal end of the device with sufficient force to pass through the subject. The device also includes a curved die at the distal end of the device for imparting a looping configuration to portions of the flexible elongated element exiting the distal end of the device, and a curved guide at the distal end for receiving the looped flexible elongated element as it returns to the distal end of the device. In a further feature of the invention, a cutting mechanism is provided to permit the looped flexible elongated element. to be separated from the remainder of the flexible elongated element. And in a further feature of the invention, the cutting mechanism is adapted to deform the trailing end of the looped flexible elongated element so that the trailing end is forced distally, toward the subject being sutured.
摘要翻译：公开了用于通过受试者的至少两个部分引入柔性细长元件的装置。在优选实施例中，装置包括近端和远端，以及前进单元，用于将柔性细长元件朝向装置的远端纵向前进，使得细长元件的近端可从该装置具有足够的力穿过受试者。该装置还包括在装置的远端处的弯曲模具，用于将环形构造用于离开装置的远端的柔性细长元件的部分，以及在远端处的弯曲导向件，用于将环形柔性细长元件接收为它返回到设备的远端。在本发明的另一个特征中，提供切割机构以允许环形柔性细长元件。与柔性细长元件的其余部分分离。而且在本发明的另一个特征中，切割机构适于使环形柔性细长元件的后端变形，使得尾端被迫向远侧朝向被缝合的被检体。

5. 发明授权

US06332889B1 Surgical suturing instrument and method of use 有权
标题翻译：手术缝合仪及其使用方法
公开(公告)号：US06332889B1
公开(公告)日：2001-12-25
申请号：US09368273
申请日：1999-08-03
申请人： Gregory E. Sancoff , Frederic P. Field , Douglas A. Fogg
发明人： Gregory E. Sancoff , Frederic P. Field , Douglas A. Fogg
IPC分类号： A61B1704
CPC分类号： A61B17/064 , A61B17/0469 , A61B17/0483 , A61B17/0491 , A61B17/12013 , A61B2017/00004 , A61B2017/0646
摘要： A device is disclosed for introducing a flexible elongated element through at least two portions of a subject. In an embodiment, the device includes a proximal end and a distal end, as well as an advancement unit for longitudinally advancing the flexible elongated element toward the distal end such that a proximal end of the elongated element may pass from the distal end of said device with sufficient force to pass through the portions of the subject. The device also includes a securing unit for variably adjusting a securing force applied by the flexible elongated element to secure together the portions of the subject.
摘要翻译：公开了用于通过受试者的至少两个部分引入柔性细长元件的装置。在一个实施例中，该装置包括近端和远端，以及用于将柔性细长元件朝向远端纵向前进的前进单元，使得细长元件的近端可以从所述装置的远端具有足够的力穿过受试者的部分。该装置还包括固定单元，用于可变地调节由柔性细长元件施加的固定力，以将主体的部分固定在一起。

6. 发明授权

US5871484A Apparatus and method for administering a biologically active substance to a bone 失效
标题翻译：将生物活性物质施用于骨骼的装置和方法
公开(公告)号：US5871484A
公开(公告)日：1999-02-16
申请号：US556230
申请日：1995-11-09
申请人： Alan R. Spievack , Douglas A. Fogg , Christopher P. Messina
发明人： Alan R. Spievack , Douglas A. Fogg , Christopher P. Messina
IPC分类号： A61B17/58 , A61B17/72 , A61M31/00 , A61B17/56
CPC分类号： A61M31/002 , A61B17/72 , Y10S606/916
摘要： A bone fastener is adapted to deliver biologically active substances to a bone site. An applicator is saturated with the substance and is disposed within an inner cavity of the fastener, near the bone site. Channels through the body of the fastener permit the substance to flow to the bone site. The substance can include therapeutic drugs, such as antibiotics, analgesics, bone morphogenic proteins, DNA, chemotherapy drugs and angiogenesis factors.
摘要翻译：骨紧固件适于将生物活性物质递送至骨部位。施用器被物质饱和，并且被设置在靠近骨部位的紧固件的内腔内。通过紧固件的身体的通道允许物质流动到骨部位。该物质可以包括治疗药物，例如抗生素，止痛剂，骨形态发生蛋白，DNA，化疗药物和血管生成因子。

7. 发明授权

US07011668B2 Surgical suturing instrument and method of use 有权
公开(公告)号：US07011668B2
公开(公告)日：2006-03-14
申请号：US10202530
申请日：2002-07-23
申请人： Gregory E. Sancoff , Douglas A. Fogg , Frederic P. Field
发明人： Gregory E. Sancoff , Douglas A. Fogg , Frederic P. Field
IPC分类号： A61B17/04
CPC分类号： A61B17/064 , A61B17/068 , A61B2017/00004 , A61B2017/0646
摘要： A device is disclosed for introducing a flexible elongated element through at least two portions of a subject. In an embodiment, the device includes a proximal end and a distal end, as well as an advancement unit for longitudinally advancing the flexible elongated element toward the distal end such that a proximal end of the elongated element may pass from the distal end of said device with sufficient force to pass through the portions of the subject. The device also includes a securing unit for variably adjusting a securing force applied by the flexible elongated element to secure together the portions of the subject.

8. 发明授权

US06786913B1 Surgical suturing instrument and method of use 有权
标题翻译：手术缝合仪及其使用方法
公开(公告)号：US06786913B1
公开(公告)日：2004-09-07
申请号：US09496305
申请日：2000-02-01
申请人： Gregory E. Sancoff , Douglas A. Fogg , Frederic P. Field
发明人： Gregory E. Sancoff , Douglas A. Fogg , Frederic P. Field
IPC分类号： A61B1704
CPC分类号： A61B17/0469 , A61B17/0483 , A61B17/0491 , A61B17/062 , A61B17/064 , A61B17/068 , A61B17/12013 , A61B2017/00004 , A61B2017/0646
摘要： A device is disclosed for introducing a flexible elongated element through at least two portions of a subject. In an embodiment, the device includes a proximal end and a distal end, as well as an advancement unit for longitudinally advancing the flexible elongated element toward the distal end such that a proximal end of the elongated element may pass from the distal end of said device with sufficient force to pass through the portions of the subject. The device also includes a securing unit for variably adjusting a securing force applied by the flexible elongated element to secure together the portions of the subject.
摘要翻译：公开了用于通过受试者的至少两个部分引入柔性细长元件的装置。在一个实施例中，该装置包括近端和远端，以及用于将柔性细长元件朝向远端纵向前进的前进单元，使得细长元件的近端可以从所述装置的远端具有足够的力穿过受试者的部分。该装置还包括固定单元，用于可变地调节由柔性细长元件施加的固定力，以将主体的部分固定在一起。

9. 发明授权

US07666194B2 Surgical suturing instrument and method of use 有权
标题翻译：手术缝合仪及其使用方法
公开(公告)号：US07666194B2
公开(公告)日：2010-02-23
申请号：US10352600
申请日：2003-01-28
申请人： Frederic P. Field , Douglas A. Fogg , Gregory E. Sancoff
发明人： Frederic P. Field , Douglas A. Fogg , Gregory E. Sancoff
IPC分类号： A61B17/04
CPC分类号： A61B17/0469 , A61B17/0467 , A61B17/0491 , A61B17/064 , A61B17/0644 , A61B17/068 , A61B17/2909 , A61B2017/00783 , A61B2017/0498 , A61B2017/06171 , A61B2017/0649 , A61F2/0063
摘要： A device is disclosed for introducing a flexible elongated element through at least two portions of a subject. In a preferred embodiment, the device includes a proximal end and a distal end, and an advancement unit for longitudinally advancing the flexible elongated element toward the distal end of the device such that a proximal end of the elongated element may exit from the distal end of the device with sufficient force to pass through the subject. The device also includes a curved die at the distal end of the device for imparting a looping configuration to portions of the flexible elongated element exiting the distal end of the device, and a curved guide at the distal end for receiving the looped flexible elongated element as it returns to the distal end of the device. In a further feature of the invention, a cutting mechanism is provided to permit the looped flexible elongated element to be separated from the remainder of the flexible elongated element. And in a further feature of the invention, the cutting mechanism is adapted to deform the trailing end of the looped flexible elongated element so that the trailing end is forced distally, toward the subject being sutured.
摘要翻译：公开了用于通过受试者的至少两个部分引入柔性细长元件的装置。在优选实施例中，装置包括近端和远端，以及前进单元，用于将柔性细长元件朝向装置的远端纵向前进，使得细长元件的近端可从该装置具有足够的力穿过受试者。该装置还包括在装置的远端处的弯曲模具，用于将环形构造用于离开装置的远端的柔性细长元件的部分，以及在远端处的弯曲导向件，用于将环形柔性细长元件接收为它返回到设备的远端。在本发明的另一个特征中，提供切割机构以允许环形柔性细长元件与柔性细长元件的其余部分分离。而且在本发明的另一个特征中，切割机构适于使环形柔性细长元件的后端变形，使得尾端被迫向远侧朝向被缝合的被检体。

10. 发明授权

US07131979B2 Surgical suturing instrument and method of use 有权
标题翻译：手术缝合仪及其使用方法
公开(公告)号：US07131979B2
公开(公告)日：2006-11-07
申请号：US10440805
申请日：2003-05-19
申请人： Joseph A. DiCarlo , Frederic P. Field , Douglas A. Fogg , Gregory E. Sancoff
发明人： Joseph A. DiCarlo , Frederic P. Field , Douglas A. Fogg , Gregory E. Sancoff
IPC分类号： A61B17/04
CPC分类号： A61B17/068 , A61B17/0467 , A61B17/0469 , A61B17/0482 , A61B17/0483 , A61B17/064 , A61B17/0644 , A61B17/2909 , A61B2017/00004 , A61B2017/00783 , A61B2017/06171 , A61B2017/0646 , A61B2017/0649 , A61B2017/2929 , A61F2/0063
摘要： A device is disclosed for introducing a flexible elongated element through at least two portions of a subject. The device includes an advancement unit for advancing the flexible elongated element toward the end of the device such that the elongated element may exit from the device with sufficient force to pass through the subject. The device also includes a curved die for imparting a looping configuration to portions of the flexible elongated element exiting the device, and a curved guide for receiving the looped flexible elongated element as it returns to the end of the device. A cutting mechanism is provided to permit the looped flexible elongated element to be separated from the remainder of the flexible elongated element. The cutting mechanism is adapted to deform the trailing end of the looped flexible elongated element so that the trailing end is forced distally, toward the subject being sutured.
摘要翻译：公开了用于通过受试者的至少两个部分引入柔性细长元件的装置。该装置包括用于使柔性细长元件朝向装置的端部前进的前进单元，使得细长元件可以以足够的力从装置中离开穿过受试者。该装置还包括弯曲模具，用于将环形结构赋予离开装置的柔性细长元件的部分，以及弯曲导向件，用于当其返回到装置的端部时接收环形柔性细长元件。提供切割机构以允许环形柔性细长元件与柔性细长元件的其余部分分离。切割机构适于使环形柔性细长元件的后端变形，使得尾端被迫向远侧，朝向被缝合的对象。

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