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1. 发明授权

US07596256B1 Computer assisted detection of lesions in volumetric medical images 有权
标题翻译：计算机辅助检测体积医学图像中的病变
公开(公告)号：US07596256B1
公开(公告)日：2009-09-29
申请号：US10246070
申请日：2002-09-16
申请人： Kaufman Arie , Dongqing Chen , Jerome Liang , Mark R. Wax
发明人： Kaufman Arie , Dongqing Chen , Jerome Liang , Mark R. Wax
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , G06T7/12 , G06T2207/10072 , G06T2207/30032
摘要： A computer-assisted detection method is provided for detecting suspicious locations of lesions in the volumetric medical images. The method includes steps of features extraction and fusion. The first step is computing gradient feature for extraction of the layer of Partial Volume Effect (LPVE) between different tissues that related to specific organs. The LPVE will combine with the result of voxel classification to fulfill the task of tissue classification. After tissue classification, the contour of tissue boundary is determined. The gradient feature is also used to determine the direction that intensity changes. This direction that intensity changes most dramatically serves as the normal vector for voxel on the contour of the tissue boundary. The second step is to determine a local surface patch on the contour for each voxel on the contour. A local landmark system is then created on that patch and the so-called Euclidean Distance Transform Vector (EDTV) is computed based on those landmarks. The EDTV is the basic shape feature for lesion detection whose development and invasion results abnormal shape change on the tissue boundary. A vector classification algorithm for pattern recognition based on EDTVs is also provided. The voxel on the contour of tissue boundary can be grouped into areas based on similar pattern to form lesion patch and local lesion volume. That area will further be analyzed for estimation of the likelihood of lesion.
摘要翻译：提供了一种用于检测体积医学图像中病变的可疑位置的计算机辅助检测方法。该方法包括特征提取和融合的步骤。第一步是在与特定器官相关的不同组织之间提取部分体积效应（LPVE）层的计算梯度特征。 LPVE将结合体素分类的结果来完成组织分类的任务。组织分类后，确定组织边界的轮廓。梯度特征也用于确定强度变化的方向。强度变化最大的方向是组织边界轮廓上的体素的法向量。第二步是为轮廓上的每个体素确定轮廓上的局部表面贴片。然后在该补丁上创建一个局部地标系统，并根据这些地标计算所谓的欧几里德距离变换向量（EDTV）。 EDTV是病变检测的基本形状特征，其发育和侵袭在组织边界上形成异常形状变化。还提供了基于EDTV的模式识别的矢量分类算法。组织边界轮廓上的体素可以基于相似的模式分组成区域，形成病变斑块和局部病变体积。该区域将进一步分析以估计病变的可能性。

2. 发明授权

US07012603B2 Motion artifact detection and correction 失效
公开(公告)号：US07012603B2
公开(公告)日：2006-03-14
申请号：US10301036
申请日：2002-11-21
申请人： Dongqing Chen , Ingmar Bitter
发明人： Dongqing Chen , Ingmar Bitter
IPC分类号： G06T15/00
CPC分类号： G06T11/008 , G06T2211/412
摘要： An apparatus and method are provided for motion artifact detection and correction, where an apparatus includes a scanning device for receiving two-dimensional image slices of an object, a rendering device in signal communication with the scanning device for rendering a three-dimensional volume representation of the two-dimensional image slices, and a correction device in signal communication with the rendering device for correcting motion artifacts within the three-dimensional volume representation; and a corresponding method for detecting motion artifacts within scan data of a region comprising an object includes creating a three-dimensional representation with volume elements of the region based on the scan data, analyzing the volume elements along a boundary of the object, and determining the existence of a motion artifact in response to the analyzing.

3. 发明申请

US20090226065A1 Sampling medical images for virtual histology 审中-公开
标题翻译：抽取医学图像进行虚拟组织学
公开(公告)号：US20090226065A1
公开(公告)日：2009-09-10
申请号：US11664833
申请日：2005-10-07
申请人： Dongqing Chen
发明人： Dongqing Chen
IPC分类号： G06K9/00 , A61B5/05 , G06T17/00 , G06F17/00
CPC分类号： G06F19/325 , G06F16/5862 , G06F19/321 , G06T7/0012 , G06T7/11 , G06T2207/10072 , G06T2207/20101 , G06T2207/30032
摘要： A system (300, 400, 800) and method (100, 200) are provided for building a digital sample library of lesions or cancers from medical images, the system (300) including an image scanner (310), image visualization or reviewing equipment (320) in signal communication with the image scanner, a digital sample library database (332), and a network for data communication connected between the library, the reviewing equipment, and the at least one scanner; and the method (100) including acquiring patient medical images (112), detecting target lesions in the acquired patient medical images (114, 116, 118), extracting digital samples (120) of the detected target lesions, collecting pathological and histological results (124, 126) of the detected target lesions, collecting diagnostic results of the detected target lesions (128), performing model selection and feature extraction (122) for each digital sample of a lesion, and storing (130) each extracted digital sample for library evolution.
摘要翻译：提供一种系统（300,400,800）和方法（100,200），用于从医学图像建立病变或癌症的数字样本库，所述系统（300）包括图像扫描仪（310），图像可视化或复查设备（320），与所述图像扫描器进行信号通信，数字样本库数据库（332）和连接在所述库，所述检查设备和所述至少一个扫描仪之间的用于数据通信的网络; 并且所述方法（100）包括获取患者医学图像（112），检测获取的患者医学图像（114,116,118）中的目标病变，提取检测到的目标病变的数字样本（120），收集病理学和组织学结果收集检测到的目标病变的诊断结果（128），为病变的每个数字样本执行模型选择和特征提取（122），并存储（130）每个提取的数字样本库演化。

4. 发明申请

US20170273666A1 METHOD FOR STORING ULTRASONIC SCAN IMAGE AND ULTRASONIC DEVICE 审中-公开
公开(公告)号：US20170273666A1
公开(公告)日：2017-09-28
申请号：US15514000
申请日：2014-09-24
申请人： Jiajiu YANG , Dongqing CHEN , Yincheng LU , Wen I an MAO , Menachem HALMANN , GENERAL ELECTRIC COMPANY
发明人： Jiajiu YANG , Dongqing CHEN , Yincheng LU , Wenlan MAO , Menachem HALMANN
IPC分类号： A61B8/08
CPC分类号： A61B8/5215 , A61B8/54 , G01N29/00 , G01N29/0636 , G01N29/0654 , G01N29/4436 , G01N29/4472
摘要： The present invention provides a method for storing an ultrasonic scan image and an ultrasonic device. The ultrasonic device may include: an image acquiring unit configured to scan a target object to obtain an image; a buffer unit configured to store the obtained image; a processing unit configured to compute a similarity of a frame of the image; and a storage unit, wherein when it is determined that the computed similarity of the frame is less than a threshold, the processing unit stores frames with a similarity equal to or greater than the threshold previous to the frame in the storage unit. Therefore, the image may be stored automatically based upon the similarity information of the frame of the ultrasonic scanning image.

5. 发明授权

US07706600B2 Enhanced virtual navigation and examination 有权
标题翻译：增强虚拟导航和检查
公开(公告)号：US07706600B2
公开(公告)日：2010-04-27
申请号：US10380210
申请日：2001-10-02
申请人： Kevin Kreeger , Sarang Lakare , Zhenrong Liang , Mark R. Wax , Ingmar Bitter , Frank Dachille , Dongqing Chen , Arie E. Kaufman
发明人： Kevin Kreeger , Sarang Lakare , Zhenrong Liang , Mark R. Wax , Ingmar Bitter , Frank Dachille , Dongqing Chen , Arie E. Kaufman
IPC分类号： G06K9/00 , G06K9/36 , A61B5/05 , G06T15/00
CPC分类号： G06T19/20 , G06T7/12 , G06T7/62 , G06T7/64 , G06T15/08 , G06T15/10 , G06T2200/04 , G06T2207/10072 , G06T2207/20044 , G06T2207/20132 , G06T2207/30028 , G06T2207/30061 , G06T2207/30172 , G06T2210/41 , G06T2219/028 , G06T2219/2012
摘要： Virtual navigation (2255) and examination of virtual objects are enhanced using methods of insuring that an entire surface to be examined has been properly viewed. A user interface (FIG. 23) identifies regions which have not been subject to examination and provides a mechanism (2250) to route the user to these regions in the 3D display. Virtual examination is further improved by the use of measuring disks (905) to enhance quantitative measurements such as diameter, distance, volume and angle. Yet another enhancement to the virtual examination of objects is a method of electronic segmentation, or cleaning, which corrects for partial volume effects occurring in an object.
摘要翻译：虚拟导航（2255）和虚拟对象的检查是通过确保正确观察整个被检查表面的方法得到增强。用户界面（图23）识别未经检查的区域，并且提供将用户定向到3D显示中的这些区域的机构（2250）。通过使用测量盘（905）进一步提高虚拟检查以增强诸如直径，距离，体积和角度的定量测量。对物体的虚拟检查的另一个增强是电子分割或清洁的方法，其校正在对象中发生的部分体积效应。

6. 发明授权

US07486811B2 System and method for performing a three-dimensional virtual examination of objects, such as internal organs 有权
公开(公告)号：US07486811B2
公开(公告)日：2009-02-03
申请号：US11613297
申请日：2006-12-20
申请人： Arie E. Kaufman , Zhengrong Liang , Mark R. Wax , Ming Wan , Dongqing Chen , Bin Li
发明人： Arie E. Kaufman , Zhengrong Liang , Mark R. Wax , Ming Wan , Dongqing Chen , Bin Li
IPC分类号： G06K9/00 , A61B6/00
CPC分类号： G06T17/00 , G06T7/0012 , G06T7/11 , G06T7/136 , G06T7/64 , G06T15/08 , G06T19/00 , G06T2207/10081 , G06T2207/20044 , G06T2207/20064 , G06T2207/30028 , G06T2207/30101
摘要： Methods for generating a three-dimensional visualization image of an object, such as an internal organ, using volume visualization techniques are provided. The techniques include a multi-scan imaging method; a multi-resolution imaging method; and a method for generating a skeleton of a complex three dimension object. The applications include virtual cystoscopy, virtual laryngoscopy, virtual angiography, among others.

7. 发明申请

US20070276214A1 Systems and Methods for Automated Segmentation, Visualization and Analysis of Medical Images 审中-公开
标题翻译：医学图像自动分割，可视化和分析的系统和方法
公开(公告)号：US20070276214A1
公开(公告)日：2007-11-29
申请号：US10580763
申请日：2004-11-26
申请人： Frank Dachille , Dongqing Chen , Michael Meissner , Wenli Cai
发明人： Frank Dachille , Dongqing Chen , Michael Meissner , Wenli Cai
IPC分类号： A61B5/00
CPC分类号： G06T7/0012 , G06F19/321 , G06T19/00 , G06T2207/30004 , G06T2210/41 , G06T2219/008
摘要： An imaging system for automated segmentation and visualization of medical images (100) includes an image processing module (107) for automatically processing image data using a set of directives (109) to identify a target object in the image data and process the image data according to a specified protocol, a rendering module (105) for automatically generating one or more images of the target object based on one or more of the directives (109) and a digital archive (110) for storing the one or more generated images. The image data may be DICOM-formatted image data (103), wherein the imaging processing module (107) extracts and processes meta-data in DICOM fields of the image data to identify the target object. The image processing module (107) directs a segmentation module (108) to segment the target object using processing parameters specified by one or more of the directives (109).
摘要翻译：一种用于医疗图像（100）的自动分割和可视化的成像系统包括图像处理模块（107），用于使用一组指令（109）自动处理图像数据，以识别图像数据中的目标对象，并根据根据指定协议，基于所述指令（109）中的一个或多个自动生成所述目标对象的一个或多个图像的再现模块（105）和用于存储所述一个或多个所生成的图像的数字存档（110）。图像数据可以是DICOM格式的图像数据（103），其中成像处理模块（107）提取并处理图像数据的DICOM字段中的元数据以识别目标对象。图像处理模块（107）引导分割模块（108）使用由一个或多个指令（109）指定的处理参数来分割目标对象。

8. 发明申请

US20070167718A1 SYSTEM AND METHOD FOR PERFORMING A THREE-DIMENTIONAL VIRTUAL EXAMINATION OF OBJECTS, SUCH AS INTERNAL ORGANS 有权
标题翻译：用于执行对象的三维虚拟检查的系统和方法，如内部机构
公开(公告)号：US20070167718A1
公开(公告)日：2007-07-19
申请号：US11613283
申请日：2006-12-20
申请人： Arie Kaufman , Zhengrong Liang , Mark Wax , Ming Wan , Dongqing Chen , Bin Li
发明人： Arie Kaufman , Zhengrong Liang , Mark Wax , Ming Wan , Dongqing Chen , Bin Li
IPC分类号： A61B5/05
CPC分类号： A61B5/055 , A61B5/726 , A61B6/032 , A61B8/483 , G06T7/11 , G06T15/08 , G06T19/00 , G06T2207/10072 , G06T2207/30028 , G06T2207/30084 , G06T2207/30172 , G06T2210/41 , G06T2219/028 , G06T2219/2004 , G09B23/28
摘要： Methods for generating a three-dimensional visualization image of an object, such as an internal organ, using volume visualization techniques are provided. The techniques include a multi-scan imaging method; a multi-resolution imaging method; and a method for generating a skeleton of a complex three dimension object. The applications include virtual cystoscopy, virtual laryngoscopy, virtual angiography, among others.
摘要翻译：提供了使用体积可视化技术来生成诸如内部器官的对象的三维可视化图像的方法。该技术包括多扫描成像方法; 多分辨率成像方法; 以及用于生成复杂三维物体的骨架的方法。应用包括虚拟膀胱镜检查，虚拟喉镜检查，虚拟血管造影等。

9. 发明申请

US20070103464A1 SYSTEM AND METHOD FOR PERFORMING A THREE-DIMENSIONAL VIRTUAL EXAMINATION OF OBJECTS, SUCH AS INTERNAL ORGANS 有权
公开(公告)号：US20070103464A1
公开(公告)日：2007-05-10
申请号：US11613306
申请日：2006-12-20
申请人： Arie Kaufman , Zhengrong Liang , Mark Wax , Ming Wan , Dongqing Chen , Bin Li
发明人： Arie Kaufman , Zhengrong Liang , Mark Wax , Ming Wan , Dongqing Chen , Bin Li
IPC分类号： G06T17/00
CPC分类号： G06T17/00 , G06T7/0012 , G06T7/11 , G06T7/136 , G06T7/64 , G06T15/08 , G06T19/00 , G06T2207/10081 , G06T2207/20044 , G06T2207/20064 , G06T2207/30028 , G06T2207/30101
摘要： Methods for generating a three-dimensional visualization image of an object, such as an internal organ, using volume visualization techniques are provided. The techniques include a multi-scan imaging method; a multi-resolution imaging method; and a method for generating a skeleton of a complex three dimension object. The applications include virtual cystoscopy, virtual laryngoscopy, virtual angiography, among others.

10. 发明授权

US07630750B2 Computer aided treatment planning 有权
标题翻译：计算机辅助治疗计划
公开(公告)号：US07630750B2
公开(公告)日：2009-12-08
申请号：US10182217
申请日：2001-02-05
申请人： Zhengrong Liang , Bin Li , Dongqing Chen , Eric E. Smouha , Clemente T. Roque , Arie E. Kaufman , Mark R. Wax , Kevin Kreeger
发明人： Zhengrong Liang , Bin Li , Dongqing Chen , Eric E. Smouha , Clemente T. Roque , Arie E. Kaufman , Mark R. Wax , Kevin Kreeger
IPC分类号： A61B5/05
CPC分类号： G06T19/003 , A61B34/10 , A61B90/36 , G06F19/00 , G06F19/321 , G06F19/3481 , G06T15/08 , G06T2210/41 , G16H50/50 , Y10S128/922
摘要： A method of computer aided treatment planning is performed by generating and manipulating a three dimensional (3D) image of a region which includes at least one anatomical structure for which treatment, such as surgery, biopsy, tissue component analysis, prosthesis implantation, radiation, chemotherapy and the like, is contemplated. A virtual intervention, which simulates at least a portion of the contemplated treatment, is performed in the 3D image. The user can then determine the effect of the intervention and interactively modify the intervention for improved treatment results. Preferably, a warning is automatically provided if the intervention poses a risk of detrimental effect. The user can navigate through the contemplated region in the 3D image and assess the results. The treatment plans can be saved for comparison and post treatment evaluation.
摘要翻译：计算机辅助治疗计划的方法通过生成和操纵包括至少一个解剖结构的区域的三维（3D）图像来进行，所述解剖结构例如手术，活组织检查，组织成分分析，假体植入，放射，化疗等等。在3D图像中执行模拟预期治疗的至少一部分的虚拟介入。然后，用户可以确定干预的效果并交互地修改干预以改善治疗结果。优选地，如果干预造成有害影响的风险，则自动提供警告。用户可以浏览3D图像中的预期区域并评估结果。治疗计划可以节省进行比较和治疗后评估。

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