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1. 发明授权

US4848094A Droplet freezing method and apparatus 失效
标题翻译：液滴冷冻方法和装置
公开(公告)号：US4848094A
公开(公告)日：1989-07-18
申请号：US188308
申请日：1988-04-29
申请人： Robert B. Davis , Donald L. DeVack
发明人： Robert B. Davis , Donald L. DeVack
IPC分类号： A23L3/36 , A23L3/375 , A61K9/16 , F25C1/00
CPC分类号： A23L3/375 , A23L3/361 , A61K9/1688 , F25C1/00
摘要： The present invention relates to a method and apparatus for the generation of essentially spherical frozen droplets of a liquid biological or organic-comprising composition. The liquid composition if fed under positive pressure through a nozzle in a manner which provides a continuous stream of the liquid composition exiting the nozzle; the continuous stream travels through a gas or vapor for a distance sufficient to cause the continuous stream to break apart, forming droplets ranging in size from about 0.6 mm to about 5 mm; the liquid composition droplets are then contacted with a cryogenic liquid capable of freezing the droplets into a solid phase; the frozen droplets are concentrated into a portion of the contacting cryogenic liquid from which they are subsequently separated.
摘要翻译：本发明涉及用于产生液体生物或含有机物的组合物的基本上球形的冷冻液滴的方法和装置。液体组合物如果以正压力通过喷嘴以提供液体组合物离开喷嘴的连续流的方式进料; 连续料流穿过气体或蒸汽足以使连续流分离的距离，形成尺寸为约0.6mm至约5mm的液滴; 然后液体组合物液滴与能够将液滴冻结成固相的低温液体接触; 冷冻的液滴被浓缩成接触的低温液体的一部分，随后从其中分离。

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