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1. 发明授权

US06394769B1 Pump having a magnetically suspended rotor with one active control axis 有权
标题翻译：泵具有具有一个主动控制轴的磁悬浮转子
公开(公告)号：US06394769B1
公开(公告)日：2002-05-28
申请号：US09602471
申请日：2000-06-23
申请人： Gill B. Bearnson , Pratap S. Khanwilkar , James W. Long , Jed C. Ludlow , Brad E. Paden , Chen Chen , Dave B. Paden , Don B. Olsen , James Antaki , Paul E. Allaire , Michael Baloh
发明人： Gill B. Bearnson , Pratap S. Khanwilkar , James W. Long , Jed C. Ludlow , Brad E. Paden , Chen Chen , Dave B. Paden , Don B. Olsen , James Antaki , Paul E. Allaire , Michael Baloh
IPC分类号： F04B1700
CPC分类号： F04D29/048 , A61M1/101 , A61M1/1015 , A61M1/1017 , A61M1/1031 , A61M1/1036 , A61M1/1086 , A61M1/12 , A61M1/122 , F04D13/0633 , F04D13/064 , F04D13/0646 , F05B2200/23 , F05B2240/515 , F16C32/0423 , F16C32/0476 , F16C2316/18 , F16C2360/44 , Y10S415/90
摘要： An inventive blood pump in accordance with this invention includes a housing that has inlet and outlet ports for receiving and discharging blood. A rotor is positioned in the housing's interior for pumping blood between the housing's inlet and outlet ports, with the rotor being capable of motion in three translational and three rotational axes. An assembly for magnetically suspending and rotating the rotor in a contact-free manner with respect to the housing includes only one electromagnetic bearing that actively controls motion of the rotor with respect to one axis selected from the rotor's three translational and three rotational axes, an electromagnetic motor that actively drives motion of the rotor with respect to one of its three rotational axes, and magnetic bearings for passively controlling motion of the rotor with respect to the remaining four of its translational and rotational axes. The inventive blood pump can also be incorporated into an artificial heart.
摘要翻译：根据本发明的创新血泵包括具有用于接收和排出血液的入口和出口的壳体。转子定位在壳体的内部，用于在壳体的入口和出口之间泵送血液，转子能够以三个平移和三个旋转轴线运动。用于相对于壳体以无接触方式磁性地悬挂和旋转转子的组件仅包括一个电磁轴承，其主动地控制转子相对于从转子的三个平移和三个旋转轴中选择的一个轴的运动，电磁主动驱动转子相对于其三个旋转轴中的一个运动的电机，以及用于被动地控制转子相对于其平移轴和旋转轴的剩余四个运动的磁轴承。本发明的血液泵还可以并入人造心脏。

2. 发明授权

US07070398B2 Axial-flow blood pump with magnetically suspended, radially and axially stabilized impeller 失效
标题翻译：具有磁悬浮，径向和轴向稳定的叶轮的轴流式血泵
公开(公告)号：US07070398B2
公开(公告)日：2006-07-04
申请号：US10949884
申请日：2004-09-24
申请人： Don B. Olsen , Paul E. Allaire , Houston G. Wood , Ronald Kipp , Wei Jiang , Zongli Lin , Guoxin Li
发明人： Don B. Olsen , Paul E. Allaire , Houston G. Wood , Ronald Kipp , Wei Jiang , Zongli Lin , Guoxin Li
IPC分类号： A61M1/10 , F04B17/00
CPC分类号： F16C32/0448 , A61M1/101 , A61M1/1015 , F16C32/0461 , F16C2316/18
摘要： A blood pump has an impeller rotatably disposed and magnetically suspended within a cavity of a stator by a plurality of magnetic bearings including an axial bearing to support the impeller axially in the cavity. The axial bearing includes adjacent impeller magnets and adjacent stator magnets with axially aligned polarities and reverse polarities with respect to adjacent magnets. A motor includes impeller magnets on the impeller and coils and poles associated with the stator. Radial permanent magnet and electromagnetic bearings are also included. The magnetic bearings and the motor have stator magnets or coils and poles disposed radially across the fluid passage from corresponding impeller magnets to define an annular gap positioned radially between the impeller and the stator, and positioned radially between all of the plurality of magnetic bearings, creating a straight through blood path without secondary flow paths.
摘要翻译：血泵具有可旋转地设置并通过包括轴向轴承的多个磁性轴承磁性地悬挂在定子的空腔内的叶轮，以便在空腔中轴向地支撑叶轮。轴向轴承包括相邻的叶轮磁体和相邻的定子磁体，其相对于相邻的磁体具有轴向对准的极性和相反的极性。电动机包括叶轮上的叶轮磁体和与定子相关联的线圈和极。还包括径向永磁体和电磁轴承。磁性轴承和电动机具有定子磁体或线圈和磁极，其径向跨越来自相应的叶轮磁体的流体通道设置，以限定径向位于叶轮和定子之间并且径向位于所有多个磁性轴承之间的环形间隙，从而产生直通血路，无二次流路。

3. 发明授权

US06595762B2 Hybrid magnetically suspended and rotated centrifugal pumping apparatus and method 有权
公开(公告)号：US06595762B2
公开(公告)日：2003-07-22
申请号：US09968690
申请日：2001-10-01
申请人： Pratap S. Khanwilkar , Paul E. Allaire , Gill B. Bearnson , Don B. Olsen , Eric H. Maslen , James W. Long
发明人： Pratap S. Khanwilkar , Paul E. Allaire , Gill B. Bearnson , Don B. Olsen , Eric H. Maslen , James W. Long
IPC分类号： F04B17100
CPC分类号： F04D29/048 , A61M1/101 , A61M1/1012 , A61M1/1015 , A61M1/1025 , A61M1/1031 , A61M1/1086 , A61M1/122 , F04D13/0666 , F05B2200/23 , F05B2240/51 , F05B2240/511 , F05B2240/515 , F16C32/044 , F16C2316/18 , Y10S415/90
摘要： An apparatus and method for a centrifugal fluid pump for pumping sensitive biological fluids, which includes (i) an integral impeller and rotor which is entirely supported by an integral combination of permanent magnets and electromagnetic bearings and rotated by an integral motor, (ii) a pump housing and arcuate passages for fluid flow and containment, (iii) a brushless driving motor embedded and integral with the pump housing, (iv) a power supply, and (v) specific electronic sensing of impeller position, velocity or acceleration using a self-sensing method and physiological control algorithm for motor speed and pump performance based upon input from the electromagnetic bearing currents and motor back emf—all fitly joined together to provide efficient, durable and low maintenance pump operation. A specially designed impeller and pump housing provide the mechanism for transport and delivery of fluid through the pump to a pump output port with reduced fluid turbulence.

4. 发明授权

US06302661B1 Electromagnetically suspended and rotated centrifugal pumping apparatus and method 有权
标题翻译：电磁悬挂和旋转式离心泵送装置及方法
公开(公告)号：US06302661B1
公开(公告)日：2001-10-16
申请号：US09459146
申请日：1999-12-10
申请人： Pratap S. Khanwilkar , Paul E. Allaire , Gill Brent Bearnson , Don B. Olsen , Eric H. Maslen , James W. Long
发明人： Pratap S. Khanwilkar , Paul E. Allaire , Gill Brent Bearnson , Don B. Olsen , Eric H. Maslen , James W. Long
IPC分类号： F04B1700
CPC分类号： F04D29/048 , A61M1/101 , A61M1/1015 , A61M1/1031 , A61M1/1036 , A61M1/1086 , A61M1/122 , A61M1/127 , F04D13/0633 , F04D13/0646 , F05B2240/515 , Y10S415/90
摘要： An apparatus and method for a centrifugal pump for pumping sensitive biological fluids which includes (i) an integral impeller and rotor which is electromagnetically supported and rotated, (ii) a pump housing and arcuate passages for fluid flow and containment, (iii) a brushless driving motor embedded and integral with the pump housing, (iv) a power supply, and (v) specific electronic sensing and control algorithms—all fitly joined together to provide efficient, durable and low maintenance pump operation. A specially designed impeller and pump housing provide the mechanism for transport and delivery of fluid through the pump to a pump output port with reduced fluid turbulence.
摘要翻译：一种用于泵送敏感生物流体的离心泵的装置和方法，其包括（i）电磁支撑和旋转的整体叶轮和转子，（ii）用于流体流动和容纳的泵壳体和弧形通道，（iii）无刷驱动电动机嵌入式并与泵壳一体化，（iv）电源，以及（v）特定的电子感应和控制算法 - 所有这些都适合连接在一起，以提供高效，耐久和低维护的泵运行。特别设计的叶轮和泵壳体提供了通过泵将流体输送和输送到具有减少的流体湍流的泵输出端口的机构。

5. 发明授权

US06270831B1 Method and apparatus for providing a conductive, amorphous non-stick coating 失效
公开(公告)号：US06270831B1
公开(公告)日：2001-08-07
申请号：US09071371
申请日：1998-04-30
申请人： B. Ajit Kumar , Pratap Khanwilkar , Don B. Olsen
发明人： B. Ajit Kumar , Pratap Khanwilkar , Don B. Olsen
IPC分类号： A61L1300
摘要： A conductive, non-stick coating is provided using a ceramic material which is conductive, flexible and provides a surface which exhibits the property of lubricity. A room or near room temperature manufacturing process produces a coating of titanium nitride on a substrate, where the coating is amorphous if the substrate is a solid material including plastics, composites, metals, magnets, and ceramics, enabling the substrate to bend without damaging the coating. The coating can also be applied as a conformal coating on a variety of substrate shapes, depending upon the application. The coating is bio-compatible and can be applied to a variety of medical devices.

6. 发明授权

US6074180A Hybrid magnetically suspended and rotated centrifugal pumping apparatus and method 失效
公开(公告)号：US6074180A
公开(公告)日：2000-06-13
申请号：US850598
申请日：1997-05-02
申请人： Pratap S. Khanwilkar , Paul E. Allaire , Gill Brent Bearnson , Don B. Olsen , Eric H. Maslen , James W. Long
发明人： Pratap S. Khanwilkar , Paul E. Allaire , Gill Brent Bearnson , Don B. Olsen , Eric H. Maslen , James W. Long
IPC分类号： A61M1/10 , F03B13/00 , F04B15/00 , F04B17/00 , F04B35/04 , F04B49/06 , F04D7/00 , F04D13/06 , F04D15/00 , F04D29/04 , F04D29/048
CPC分类号： F04D29/048 , A61M1/101 , A61M1/1015 , A61M1/1031 , F04D13/0666 , F16C32/044 , F05B2200/23 , F05B2240/51 , F05B2240/511 , F05B2240/515 , Y10S415/90
摘要： An apparatus and method for a centrifugal fluid pump for pumping sensitive biological fluids, which includes (i) an integral impeller and rotor which is entirely supported by an integral combination of permanent magnets and electromagnetic bearings and rotated by an integral motor, (ii) a pump housing and arcuate passages for fluid flow and containment, (iii) a brushless driving motor embedded and integral with the pump housing, (iv) a power supply, and (v) specific electronic sensing of impeller position, velocity or acceleration using a self-sensing method and physiological control algorithm for motor speed and pump performance based upon input from the electromagnetic bearing currents and motor back emf--all fitly joined together to provide efficient, durable and low maintenance pump operation. A specially designed impeller and pump housing provide the mechanism for transport and delivery of fluid through the pump to a pump output port with reduced fluid turbulence.

7. 发明授权

US4981484A Modified elliptical artificial heart 失效
标题翻译：修饰椭圆形人造心脏
公开(公告)号：US4981484A
公开(公告)日：1991-01-01
申请号：US438810
申请日：1989-11-20
申请人： John W. Holfert , Don B. Olsen
发明人： John W. Holfert , Don B. Olsen
IPC分类号： A61M1/10 , A61M1/12
CPC分类号： A61M1/1037 , A61M1/1096 , A61M1/122 , A61M1/106
摘要： An artificial heart device for producing heart pumping action as part of a total artificial heart implant comprising a housing of elongate configuration enclosing a pumping volume of sufficient capacity to provide adequate blood flow within the living being. A deformable diaphragm structure is attached at its perimeter to an interior housing surface approximately at the largest perimeter of the pumping volume to form a deformable partition deviding the pumping volume into a blood chamber and a drive chamber. The diaphragm structure has a modified hemi-ellipsoidal configuration when fully extended, modification being represented by four sections of substantially equal quadrants formed by intersection of the diaphragm structure with two orthogonal planes oriented in parallel relationship with the vertical axis. The curvature of each medial section of each quadrant is reduced or flattened to form a medial section having a lower profile as compared to surrounding ellipsoidal curvature. This structure reduces occurrence of bi-axial folding and enhancing random folding activity within the diaphragm. Valve inlet and outlet means are coupled to the housing in communication with the blood flow chamber for attachment along with the circulatory system of a living being. Pumping means are provided for actuating alternating extension and collapse of the diaphragm structure with respect to the drive chamber to simulate pumping action of the natural heart.
摘要翻译：一种人造心脏装置，用于作为总人造心脏植入物的一部分产生心脏抽吸作用，其包括具有足够容量的泵送体积的细长结构的壳体，以在生命体内提供足够的血液流动。可变形隔膜结构在其周边附近连接到内部壳体表面，大致在泵送体积的最大周边处，以形成将泵送体积分离成血液室和驱动室的可变形分隔件。当完全延伸时，膜片结构具有改进的半椭圆形结构，其修改由基本上相等的象限的四个部分表示，所述四个部分通过光阑结构与垂直轴平行关系定向的两个正交平面的交点形成。每个象限的每个中间部分的曲率被减小或变平，以形成与周围椭圆曲率相比具有较低轮廓的中间部分。这种结构减少了双向折叠的发生，并增强了隔膜内的随机折叠活动。阀入口和出口装置连接到与血流室连通的壳体，用于与活体的循环系统一起附着。提供泵送装置用于致动隔膜结构相对于驱动室的交替延伸和塌缩，以模拟天然心脏的泵送作用。

8. 发明授权

US07229258B2 Streamlined unobstructed one-pass axial-flow pump 失效
标题翻译：流线型无阻碍单向轴流泵
公开(公告)号：US07229258B2
公开(公告)日：2007-06-12
申请号：US10950176
申请日：2004-09-24
申请人： Houston G. Wood , Paul E. Allaire , Don B. Olsen , Steven W. Day , Xinwei Song , Alex Untaroiu , Amy Throckmorton
发明人： Houston G. Wood , Paul E. Allaire , Don B. Olsen , Steven W. Day , Xinwei Song , Alex Untaroiu , Amy Throckmorton
IPC分类号： F04B35/04 , A61M1/10
CPC分类号： F16C32/044 , F16C2316/18
摘要： A blood pump has an impeller rotatably disposed and magnetically suspended within a cavity of a stator by a plurality of magnetic bearings (passive permanent and active electromagnetic) having impeller magnets on the impeller and stator magnets or coils/poles on the stator. A motor includes impeller magnets on the impeller and coils/poles associated with the stator. A single, annular blood flow path extends axially through the cavity between the impeller and the stator, and between the impeller magnets on the impeller and the stator magnets or the coils/poles on the stator.
摘要翻译：血泵具有通过叶轮上的叶轮磁体和定子上的定子磁体或线圈/磁极上的多个磁性轴承（被动永磁和有源电磁）可旋转地设置并磁悬浮在定子的空腔内的叶轮。电动机包括叶轮上的叶轮磁体和与定子相关联的线圈/极。单个环形血流路径轴向延伸通过叶轮和定子之间的空腔，以及在叶轮上的叶轮磁体和定子磁体或定子上的线圈/极之间。

9. 发明授权

US5326344A Magnetically suspended and rotated rotor 失效
标题翻译：磁悬浮和转动转子
公开(公告)号：US5326344A
公开(公告)日：1994-07-05
申请号：US953409
申请日：1992-11-09
申请人： Gunter W. Bramm , Don B. Olsen
发明人： Gunter W. Bramm , Don B. Olsen
IPC分类号： A61M1/10 , F04D13/06 , F04D15/00 , F04D29/04 , F04D29/048 , F16C39/06 , H02K7/09 , A61N1/10 , A61N1/362 , B63H3/00 , F04B17/00
CPC分类号： F04D29/048 , A61M1/101 , A61M1/1015 , A61M1/1031 , F04D13/06 , F04D15/0066 , F16C39/063 , H02K7/09
摘要： The impellor of a blood pump is supported by permanent magnets on the impellor and pump housing and stabilized by an electromagnet on the housing. A control circuit supplies current to the electromagnet to maintain the axial position of the impellor at a control position in which the impellor is in mechanical equilibrium under permanent magnet forces and static axial forces on the impellor to minimize energy consumption in the support of the impellor. The impellor is rotated magnetically and stator coils in the housing are supplied with electric currents having a frequency and amplitude adjusted in relation to blood pressure at the pump inlet to match the flow characteristics of the pump to physiological characteristics of the natural heart. A cavity is formed in the impellor to match the average specific gravity of the impellor and portions of the suspension and drive systems thereon to the specific gravity of blood to further minimize power consumption by the pump. A valve member can be formed on the impellor to mate with a restriction in the pump inlet for pumps used to assist the pumping action of the natural heart.
摘要翻译：血泵的推进器由叶轮和泵壳体上的永磁体支撑并由壳体上的电磁体稳定。控制电路向电磁铁提供电流，以将叶轮的轴向位置保持在控制位置，在该控制位置中，叶轮在永久磁力下处于机械平衡状态，并且在叶轮上具有静态轴向力，以最小化叶轮支撑件的能量消耗。驱动器被磁性旋转，壳体中的定子线圈被提供有相对于泵入口处的血压调整的频率和幅度的电流，以将泵的流动特性与自然心脏的生理特征相匹配。在叶轮中形成空腔以将叶轮的平均比重及其上的悬架和驱动系统的部分与血液的比重匹配，以进一步最小化泵的功率消耗。阀构件可以形成在叶轮上以与用于辅助自然心脏的泵送动作的泵的泵入口中的限制配合。

10. 发明授权

US5078741A Magnetically suspended and rotated rotor 失效
标题翻译：磁悬浮旋转转子
公开(公告)号：US5078741A
公开(公告)日：1992-01-07
申请号：US510313
申请日：1990-04-16
申请人： Gunter W. Bramm , Don B. Olsen
发明人： Gunter W. Bramm , Don B. Olsen
IPC分类号： A61M1/10 , F04D13/06 , F04D15/00 , F04D29/04 , F04D29/048 , F16C39/06 , H02K7/09
CPC分类号： F04D29/048 , A61M1/101 , A61M1/1015 , A61M1/1031 , F04D13/06 , F04D15/0066 , F16C32/0444 , H02K7/09
摘要： The impellor of a blood pump is supported by permanent magnets on the impellor and pump housing and stabilized by an electromagnet on the housing. A control circuit supplies current to the electromagnet to maintain the axial position of the impellor at a control position in which the impellor is in mechanical equilibrium under permanent magnet forces and static axial forces on the impellor to minimize energy consumption in the support of the impellor. The impellor is rotated magnetically and stator coils in the housing are supplied with electric currents having a frequency and amplitude adjusted in relation to blood pressure at the pump inlet to match the flow characteristics of the pump to physiological characteristics of the natural heart. A cavity is formed in the impellor to match the average specific gravity of the impellor and portions of the suspension and drive systems thereon to the specific gravity of blood to further minimize power consumption by the pump. A valve member can be formed on the impellor to mate with a restriction in the pump inlet for pumps used to assist the pumping action of the natural heart.
摘要翻译：血泵的推进器由叶轮和泵壳体上的永磁体支撑并由壳体上的电磁体稳定。控制电路向电磁铁提供电流，以将叶轮的轴向位置保持在控制位置，在该控制位置中，叶轮在永久磁力下处于机械平衡状态，并且在叶轮上具有静态轴向力，以最小化叶轮支撑件的能量消耗。驱动器被磁性旋转，壳体中的定子线圈被提供有相对于泵入口处的血压调整的频率和幅度的电流，以将泵的流动特性与自然心脏的生理特征相匹配。在叶轮中形成空腔以将叶轮的平均比重及其上的悬架和驱动系统的部分与血液的比重匹配，以进一步最小化泵的功率消耗。阀构件可以形成在叶轮上以与用于辅助自然心脏的泵送动作的泵的泵入口中的限制配合。

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