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1. 发明专利

JP2008212691A Method and apparatus for lesion localization, definition and verification 有权
标题翻译：用于LESION定位，定义和验证的方法和装置
公开(公告)号：JP2008212691A
公开(公告)日：2008-09-18
申请号：JP2008068612
申请日：2008-03-18
申请人： Tony Falco , Dimitre Hristov , ファルコ,トニー , リストフ,ディミトル
发明人： FALCO TONY , HRISTOV DIMITRE
IPC分类号： A61B8/08 , G01R33/28 , A61B5/055 , A61B6/03 , A61B8/00 , A61N5/10 , G01T1/161
CPC分类号： A61N5/1049 , A61B8/08 , A61B8/4245 , A61N2005/105 , A61N2005/1051 , A61N2005/1058
摘要： PROBLEM TO BE SOLVED: To provide a method and apparatus for lesion or organ definition for the purpose of radiation treatment planning localization and treatment position verification. SOLUTION: The apparatus uses a combination of an ultrasonic imaging system and a diagnostic imaging system to acquire localization ultrasonic images referenced in the coordinate space of the diagnostic imaging system through the use of a position sensing system. The method compares the location of the lesion in the localization ultrasonic images with the position of the lesion in ultrasonic images taken while the patient lies on the treatment table of a therapy treatment unit, suggests corrective measures to place the lesion in its intended treatment position and performs the correction upon confirmation from qualified personnel. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：为了辐射治疗计划的定位和治疗位置验证的目的，提供用于病变或器官定义的方法和装置。解决方案：该装置使用超声波成像系统和诊断成像系统的组合来通过使用位置感测系统获取在诊断成像系统的坐标空间中参考的定位超声图像。该方法将定位超声图像中的病变位置与患者置于治疗处理单元的治疗台上的超声图像中的病变位置进行比较，提出将病变置于其预期治疗位置的纠正措施，以及经合格人员确认后进行更正。版权所有（C）2008，JPO＆INPIT

2. 发明专利

JP2007054641A Method and apparatus for resolution and confirmation of lesion 审中-公开
标题翻译：用于分辨和确认LESION的方法和装置
公开(公告)号：JP2007054641A
公开(公告)日：2007-03-08
申请号：JP2006271724
申请日：2006-10-03
申请人： Tony Falco , Dimitre Hristov , ファルコ,トニー , リストフ,ディミトル
发明人： FALCO TONY , HRISTOV DIMITRE
IPC分类号： A61B8/00 , G01R33/28 , A61B5/055 , A61B6/03 , A61B8/08 , A61N5/10 , G01T1/161
CPC分类号： A61N5/1049 , A61B8/08 , A61B8/4245 , A61N2005/105 , A61N2005/1051 , A61N2005/1058
摘要： PROBLEM TO BE SOLVED: To provide a method and an apparatus for resolution, positional measurement and confirmation and correction of the treating position of a lesion or an organ for the purpose of planning of the radiotherapy. SOLUTION: A combination of an ultrasonic imaging system 008 and a diagnostic imaging system 002 selected from a group including an MRI, a CT and a PET is used for securing the positional measurement of the ultrasonic image related to a coordinate space of the diagnostic imaging system through the usage of a positional sensing system. The position of the lesion 010 in a positional measurement ultrasonic image and the position of the lesion in the ultrasonic image captured while a patient lies on a treatment table of a therapy unit are compared to suggest the correct plan for arranging the lesion at its subjective treatment position and the correction by the confirmation acquired from a qualified person is executed. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：为了规划放射疗法的目的，提供一种用于分辨率，位置测量和确定和校正病变或器官的治疗位置的方法和装置。超声波成像系统008和从包括MRI，CT和PET的组中选择的诊断成像系统002的组合被用于确保与超声成像系统008的坐标空间相关的超声波图像的位置测量诊断成像系统通过使用位置检测系统。比较位置测量超声波图像中的病变010的位置和患者处于治疗单元的治疗台时所拍摄的超声波图像中的病变位置，以建议在其主观治疗中排列病变的正确计划执行由合格人员取得的确认的更正。版权所有（C）2007，JPO＆INPIT

3. 发明申请

US20130142310A1 DYNAMIC MULTI-AXES TRAJECTORY OPTIMIZATION AND DELIVERY METHOD FOR RADIATION TREATMENT 审中-公开
标题翻译：用于辐射处理的动态多轴测距优化和传送方法
公开(公告)号：US20130142310A1
公开(公告)日：2013-06-06
申请号：US13490450
申请日：2012-06-06
申请人： Benjamin Pooya Fahimian , Lei Xing , Sarah Geneser , Dimitre Hristov
发明人： Benjamin Pooya Fahimian , Lei Xing , Sarah Geneser , Dimitre Hristov
IPC分类号： A61N5/10
CPC分类号： A61N5/103 , A61N5/1047 , A61N5/1082
摘要： Embodiments of the present invention provide methods for improved radiation treatment and imaging of solid cancers utilizing radiation beam trajectory optimization techniques to obtain conformal radiation coverage of tissue that is targeted to receive radiation, while minimizing exposure of healthy tissue and organs to harmful, unnecessary radiation.
摘要翻译：本发明的实施例提供了用于利用辐射束轨迹优化技术改进放射治疗和固体癌成像的方法，以获得靶向接受辐射的组织的适形辐射覆盖，同时使健康组织和器官暴露于有害的不必要的辐射最小化。

4. 发明授权

US07551759B2 Target identification using time-based data sets 有权
标题翻译：使用基于时间的数据集进行目标识别
公开(公告)号：US07551759B2
公开(公告)日：2009-06-23
申请号：US11007068
申请日：2004-12-07
申请人： Dimitre Hristov Hristov , Gangadharan M. Bijumon
发明人： Dimitre Hristov Hristov , Gangadharan M. Bijumon
IPC分类号： G06K9/00 , A61B1/00
CPC分类号： A61B6/032 , A61B6/463 , A61B6/466 , A61B6/541 , A61N5/103
摘要： A system includes acquisition of a first image of a portion of a body, the first image representing the portion during a first phase of motion, acquisition of a second image of the portion of the body, the second image representing the portion during a second phase of motion, generation of a composite image based on the first image and the second image, the composite image indicating a position of a target during the first phase of motion and a position of the target during the second phase of motion, and identification of a target region based on the composite image.
摘要翻译：一种系统包括获取身体的一部分的第一图像，在第一运动阶段期间表示该部分的第一图像，获取身体部分的第二图像，在第二阶段期间表示该部分的第二图像基于第一图像和第二图像生成合成图像，在第一运动阶段期间指示目标的位置的合成图像和在第二运动阶段期间的目标的位置，以及基于合成图像的目标区域。

5. 发明申请

US20050201604A1 Time-based system to link periodic X-ray images 有权
标题翻译：基于时间的系统来连接周期性X射线图像
公开(公告)号：US20050201604A1
公开(公告)日：2005-09-15
申请号：US10796733
申请日：2004-03-09
申请人： Dimitre Hristov
发明人： Dimitre Hristov
IPC分类号： G06K9/00 , G06K9/36
CPC分类号： G06T11/008 , G06T2211/412
摘要： A system includes acquisition of a plurality of images of a first portion of a body undergoing substantially periodic motion, each of the plurality of images associated with a respective time, determination of a correlation between at least two of the plurality of images, and determination of a period of the periodic motion based on the respective times associated with the at least two of the plurality of images.
摘要翻译：一种系统包括获取经历基本上周期性运动的身体的第一部分的多个图像，所述多个图像中的每一个与相应的时间相关联，确定所述多个图像中的至少两个图像之间的相关性，以及确定基于与所述多个图像中的所述至少两个图像相关联的相应时间的所述周期性运动的周期。

6. 发明授权

US07366336B2 System to link periodic X-ray images 有权
标题翻译：连接定期X射线图像的系统
公开(公告)号：US07366336B2
公开(公告)日：2008-04-29
申请号：US10796327
申请日：2004-03-09
申请人： Dimitre Hristov Hristov
发明人： Dimitre Hristov Hristov
IPC分类号： G06K9/00
CPC分类号： G06T7/38 , G06T2207/10076 , G06T2207/10081 , G06T2207/30004
摘要： A system includes acquisition of a plurality of images of a first portion of a body undergoing substantially periodic motion, acquisition of a second plurality of images of a second portion of the body, the second portion comprising a portion of the first portion, and determination of a correlation between at least one of the first plurality of images and at least one of the second plurality of images. A system may also include generation of a combined image of the first portion and the second portion based on the at least one of the first plurality of images and the at least one of the second plurality of images, the combined image corresponding to a first phase of the periodic motion.
摘要翻译：一种系统包括获取经历基本上周期性运动的身体的第一部分的多个图像，获取身体的第二部分的第二多个图像，第二部分包括第一部分的一部分，以及确定所述第一多个图像中的至少一个与所述第二多个图像中的至少一个之间的相关性。系统还可以包括基于第一多个图像中的至少一个和第二多个图像中的至少一个图像来生成第一部分和第二部分的组合图像，该组合图像对应于第一阶段的周期运动。

7. 发明申请

US20060122499A1 Target identification using time-based data sets 有权
公开(公告)号：US20060122499A1
公开(公告)日：2006-06-08
申请号：US11007068
申请日：2004-12-07
申请人： Dimitre Hristov , Gangadharan Bijumon
发明人： Dimitre Hristov , Gangadharan Bijumon
IPC分类号： A61B5/05
CPC分类号： A61B6/032 , A61B6/463 , A61B6/466 , A61B6/541 , A61N5/103
摘要： A system includes acquisition of a first image of a portion of a body, the first image representing the portion during a first phase of motion, acquisition of a second image of the portion of the body, the second image representing the portion during a second phase of motion, generation of a composite image based on the first image and the second image, the composite image indicating a position of a target during the first phase of motion and a position of the target during the second phase of motion, and identification of a target region based on the composite image.

8. 发明申请

US20050116173A1 Variable gain imaging 有权
标题翻译：可变增益成像
公开(公告)号：US20050116173A1
公开(公告)日：2005-06-02
申请号：US10726449
申请日：2003-12-02
申请人： Dimitre Hristov , Zirao Zheng
发明人： Dimitre Hristov , Zirao Zheng
IPC分类号： G01T1/20
CPC分类号： G01T1/2018
摘要： An apparatus may include a scintillator to emit light, imaging elements to capture image information based on received light, and an optical filter disposed between the scintillator and the imaging elements, wherein an opacity of the optical filter is controllable.
摘要翻译：一种装置可以包括发射光的闪烁器，基于接收的光捕获图像信息的成像元件和设置在闪烁器和成像元件之间的滤光器，其中滤光器的不透明度是可控的。

9. 发明授权

US07388976B2 Time-based system to link periodic X-ray images 有权
标题翻译：基于时间的系统来连接周期性X射线图像
公开(公告)号：US07388976B2
公开(公告)日：2008-06-17
申请号：US10796733
申请日：2004-03-09
申请人： Dimitre Hristov Hristov
发明人： Dimitre Hristov Hristov
IPC分类号： G06K9/00
CPC分类号： G06T11/008 , G06T2211/412
摘要： A system includes acquisition of a plurality of images of a first portion of a body undergoing substantially periodic motion, each of the plurality of images associated with a respective time, determination of a correlation between at least two of the plurality of images, and determination of a period of the periodic motion based on the respective times associated with the at least two of the plurality of images.
摘要翻译：一种系统包括获取经历基本上周期性运动的身体的第一部分的多个图像，所述多个图像中的每一个与相应的时间相关联，确定所述多个图像中的至少两个图像之间的相关性，以及确定基于与所述多个图像中的所述至少两个图像相关联的相应时间的所述周期性运动的周期。

10. 发明授权

US07697662B2 Online verification of radiation field, collimator position and/or leakage 有权
标题翻译：在线验证辐射场，准直器位置和/或泄漏
公开(公告)号：US07697662B2
公开(公告)日：2010-04-13
申请号：US11900433
申请日：2007-09-11
申请人： Jonathan S. Maltz , Dimitre Hristov Hristov
发明人： Jonathan S. Maltz , Dimitre Hristov Hristov
IPC分类号： A61N5/10 , G21K1/02
CPC分类号： A61N5/1048 , A61N2005/1054
摘要： A system includes delivery of treatment radiation to a target, acquisition of an image representing the treatment radiation during delivery of the treatment radiation, determination of a position of a leaf of a collimator delivery of the treatment radiation based on the image, and presentation of a notification of an error during delivery of the treatment radiation based on the determined position.
摘要翻译：系统包括将治疗辐射传送到目标，在递送治疗辐射期间获取表示治疗辐射的图像，基于图像确定治疗辐射的准直仪传送的位置，以及呈现基于确定的位置在处理辐射的传送期间通知错误。

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