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1. 发明授权

US06328689B1 Lung constriction apparatus and method 有权
标题翻译：肺缩窄装置及方法
公开(公告)号：US06328689B1
公开(公告)日：2001-12-11
申请号：US09534244
申请日：2000-03-23
申请人： Hugo X. Gonzalez , Diane M. Muff , William A. Sirokman
发明人： Hugo X. Gonzalez , Diane M. Muff , William A. Sirokman
IPC分类号： A61F200
CPC分类号： A61B17/12 , A61B17/00234 , A61F2/0063
摘要： A lung constriction device and method provide lung air leak suppression or lung volume reduction. The lung constriction device includes a jacket of flexible material. The jacket is configured to cover at least a portion of a lung. The jacket is further configured to receive the lung portion as it is drawn therein. The jacket may be expandable and held in an expanded condition as the lung tissue is drawn into the jacket. Thereafter, the jacket is permitted to collapse about the lung portion to constrict the lung portion. The jacket may alternatively be nonexpandable. As the lung tissue is drawn into the jacket, it will collapse. Once disposed in the jacket, the jacket constricts the lung tissue to provide leakage suppression or lung volume reduction. The jacket may further be severable so that after the lung portion is drawn into the jacket, the jacket may be severed to section the lung portion.
摘要翻译：肺收缩装置和方法提供肺空气泄漏抑制或肺体积减少。肺收缩装置包括柔性材料夹套。护套构造成覆盖肺的至少一部分。外套进一步构造成在其被抽吸时接收肺部分。当肺组织被拉入夹套时，护套可以是可扩张的并且保持在扩张状态。此后，允许护套围绕肺部折叠以收缩肺部。夹克可以替代地不可调。当肺组织被拉入夹套时，它会塌陷。一旦被设置在护套中，护套会收缩肺组织以提供泄漏抑制或减少肺体积。护套可以进一步可分离，使得在将肺部分拉入护套之后，护套可以被切断以切断肺部。

2. 发明授权

US5628774A Cardiac lead with composite insulating structure 失效
标题翻译：心脏导联复合绝缘结构
公开(公告)号：US5628774A
公开(公告)日：1997-05-13
申请号：US429886
申请日：1995-04-27
申请人： John R. Helland , Diane M. Muff
发明人： John R. Helland , Diane M. Muff
IPC分类号： A61N1/04 , A61N1/05
CPC分类号： A61N1/0563 , A61N1/056
摘要： A lead for implantation in a human body exhibits improved combined biodegradation, blood surface compatibility, wear and flexibility characteristics. The lead includes at least one electrode and at least one connector connecting the electrode to a connector at the proximal end of the lead. An outer insulation surrounds the at least one conductor, and includes a first insulation formed of silicone encircling the at least one conductor, and a second insulation formed from polyurethane encircling the silicone rubber insulation.
摘要翻译：植入人体的铅显示出改进的组合生物降解，血液表面相容性，磨损和柔韧性特征。引线包括至少一个电极和将电极连接到引线近端的连接器的至少一个连接器。外部绝缘体包围至少一个导体，并且包括由环绕至少一个导体的硅树脂形成的第一绝缘体和由环氧树脂绝缘体的聚氨酯形成的第二绝缘体。

3. 发明授权

US5318572A High efficiency tissue stimulating and signal sensing electrode 失效
标题翻译：高效组织刺激和信号感应电极
公开(公告)号：US5318572A
公开(公告)日：1994-06-07
申请号：US892463
申请日：1992-06-02
申请人： John R. Helland , Diane M. Muff
发明人： John R. Helland , Diane M. Muff
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/0565
摘要： A pacing lead having a porous electrode of platinum-iridium with recessed areas or grooves formed into the surface. The grooves allow for acute electrode stabilization as a result of clot formation and endocardial tissue capture during insertion and immediate immobilization upon implant. At least one layer of a porous coating of 20-200 micron diameter spherical particles are deposited on the surface of the base electrode to obtain a porous macrostructure for promoting chronic tissue ingrowth. Additionally, a microstructure surface coating is applied to increase the active surface area and enhance electrical efficiency by lowering electrochemical polarization and increasing electrical capacitance.
摘要翻译：具有铂 - 铱的多孔电极的起搏引线，具有形成在表面中的凹陷区域或凹槽。沟槽允许由于凝块形成和插入期间的心内膜组织捕获以及植入物立即固定而导致的急性电极稳定化。至少一层20-200微米直径的球形颗粒的多孔涂层沉积在基底表面上，以获得促进慢性组织向内生长的多孔宏观结构。另外，通过降低电化学极化和增加电容，施加微结构表面涂层以增加活性表面积并提高电效率。

4. 发明授权

US5476493A Implantable lead having self-locking suture sleeve 失效
标题翻译：可植入铅具有自锁缝合套管
公开(公告)号：US5476493A
公开(公告)日：1995-12-19
申请号：US64681
申请日：1993-05-19
申请人： Diane M. Muff
发明人： Diane M. Muff
IPC分类号： A61N1/05 , A61N1/362
CPC分类号： A61N1/057 , A61N2001/0582
摘要： A movable self-locking suture sleeve which can be securely positioned on the lead body of a pacing lead. The self-locking suture sleeve includes first and second cooperative rigid elements interconnected by a flexible tubing element. The tubing element is constructed from a woven mesh designed to constrict when stretched. A resilient element or spring is interposed between the first and second cooperative rigid elements, tending to force the cooperative rigid elements axially apart. Once the suture sleeve is moved into position, a self-locking feature allows the suture sleeve to secure itself to the lead body.
摘要翻译：可移动的自锁缝合套管，其可以牢固地定位在起搏引线的引导体上。自锁缝合套管包括通过柔性管道元件互连的第一和第二协作刚性元件。管道元件由设计成在拉伸时收缩的编织网构造。弹性元件或弹簧介于第一和第二协作刚性元件之间，倾向于迫使协作刚性元件轴向分开。一旦缝合套筒移动到位置，自锁特征允许缝合套筒将其自身固定到引线体上。

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