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    • 2. 发明授权
    • Individual packages for absorbent interlabial devices
    • 用于吸收性阴唇间器件的单独包装
    • US06299607B1
    • 2001-10-09
    • US08975795
    • 1997-11-21
    • Thomas Ward Osborn, IIIDiane Dunn Farris
    • Thomas Ward Osborn, IIIDiane Dunn Farris
    • A61F1315
    • A61F13/55165A61F13/15211A61F13/15252A61F13/47209A61F15/002Y10S604/904
    • Individual packages to assist the hygienic insertion of an absorbent device into the interlabial space of a female user are disclosed. The individual package includes a wrapper for packaging the absorbent device. The wrapper provides a flexible sheet which is wrapped around the absorbent device. The wrapper being at least partially removable from around the absorbent device wherein at least a portion of the wrapper remains between a user's hands and the absorbent device when the absorbent device is inserted into the interlabial space to prevent the user's hands from contacting the absorbent device for hygienic insertion. The wrapper is folded about the absorbent device relative to the longitudinal axis of the lower portion forming a longitudinal fold, an opposing open end, and transverse side edges. The opposing open end and transverse side edges are sealed forming the individual package.
    • 公开了用于辅助将吸收装置卫生地插入女用户的阴唇间空间的单个包装。 单个包装包括用于包装吸收装置的包装物。 包装纸提供缠绕在吸收装置上的柔性片材。 包装物至少部分地可从吸收装置周围移除,其中当吸收装置插入阴唇间空间中时,包装物的至少一部分保留在使用者的手和吸收装置之间,以防止使用者的手与吸收装置接触 卫生插入。 包装物围绕吸收装置相对于下部的纵向轴线折叠,形成纵向折叠,相对的开口端和横向侧边缘。 相对的开口端和横向侧边缘被密封形成单个包装。
    • 3. 发明申请
    • Rapid direct sequence analysis of multi-exon genes
    • 多外显子基因的快速直接序列分析
    • US20060223062A1
    • 2006-10-05
    • US10539178
    • 2003-12-17
    • Kevin FlaniganRobert WeissDiane DunnAndrew Niederhausern
    • Kevin FlaniganRobert WeissDiane DunnAndrew Niederhausern
    • C12Q1/68C12P19/34
    • C12Q1/6883C12Q2600/156
    • Disclosed is a Single Condition Amplification/Internal Primer (SCAIP) sequencing method which allows for the rapid, accurate, and economical analysis of any large multi-exon gene. The method can be used to detect genomic mutations in any large multi-exon gene including the dystrophin gene. In some forms, the method can rely on amplification of a large number of exons at a single set of PCR temperatures with a first set of amplification primers followed by sequencing without optimization of individual amplicon conditions, using a second, internal set of sequencing primers. The SCAIP method provides for the identification and analysis of specific individual genomic mutations such as deletions, point mutations, frameshifts, or combinations thereof, in gene complexes with multiple exons/introns spanning large genomic regions.
    • 公开了单条件扩增/内部引物(SCAIP)测序方法,其允许任何大的多外显子基因的快速,准确和经济的分析。 该方法可用于检测任何大的多外显子基因(包括肌营养不良蛋白基因)中的基因组突变。 在某些形式中,该方法可以依赖于在单一PCR温度下用第一组扩增引物扩增大量外显子,然后使用第二组内部测序引物优化单个扩增子条件,进行测序。 SCAIP方法在跨越大的基因组区域的多个外显子/内含子的基因复合物中提供鉴定和分析特定的单个基因组突变,例如缺失,点突变,移位或其组合。