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1. 发明授权

US09254946B2 Pierceable cap having single frangible seal 有权
标题翻译：具有单个易碎密封的可穿戴帽
公开(公告)号：US09254946B2
公开(公告)日：2016-02-09
申请号：US13985182
申请日：2012-02-14
申请人： Ammon David Lentz , Allan M. Kiang
发明人： Ammon David Lentz , Allan M. Kiang
IPC分类号： B65D47/36 , B01L3/00 , B65D51/00
CPC分类号： B65D47/36 , B01L3/50825 , B01L2200/0684 , B01L2200/141 , B01L2200/18 , B01L2300/044 , B01L2300/048 , B01L2300/123 , B65D51/002
摘要： A pierceable cap 411 may be used for containing sample specimens during storage and transport. The pierceable cap 411 may prevent unwanted escape of sample specimen before transfer with a transfer device 43. The pierceable cap 411 may fit over a vessel 21. An access port in the pierceable cap 411 may allow passage of a tip 41 of a transfer device 43 through the pierceable cap 411. Single or multiple frangible layers 415, 416 may be disposed across the access port. Single frangible layers 415, 416 are configured to prevent venting upon initially being pierced by a transfer device 43 but to allow venting as the transfer device 43 is advanced through the frangible layer 415, 416.
摘要翻译：在可储存和运输过程中，可以使用可刺穿的盖子411来容纳样品。可穿透帽411可以防止样品在与转移装置43转移之前不想要的逸出。可刺穿帽411可以装配在容器21上。可刺穿帽411中的进入口可以允许传送装置43的尖端41通过穿过可刺穿帽411.可以跨越进入端口布置单个或多个易碎层415,416。单个易碎层415,416被构造成防止最初被传送装置43刺穿时的通气，但是当传送装置43前进穿过易碎层415,416时允许排气。

2. 发明授权

US08387810B2 Pierceable cap having piercing extensions for a sample container 有权
标题翻译：具有用于样品容器的穿孔延伸部的可穿透帽
公开(公告)号：US08387810B2
公开(公告)日：2013-03-05
申请号：US11785144
申请日：2007-04-16
申请人： Dwight Livingston , Dustin Diemert , Ammon David Lentz
发明人： Dwight Livingston , Dustin Diemert , Ammon David Lentz
IPC分类号： B65D47/36 , B65D47/38 , B01L3/00 , A61J1/05
CPC分类号： B65D51/224 , B01L3/50825 , B01L2300/044 , B01L2300/0672 , B01L2400/0683
摘要： A pierceable cap may be used for containing sample specimens during storage and transport. The pierceable cap may prevent unwanted escape of sample specimen before transfer with a transfer device. The pierceable cap may fit over a vessel. An access port in the pierceable cap may allow passage of a tip of a transfer device though the pierceable cap. A frangible layer may be disposed across the access port. One or more extensions proximate to the frangible layer may be coupled to the pierceable cap by coupling regions or other similar devices. The one or more extension may rotate around the one or more coupling regions during insertion of the transfer device. The movement of the one or more extensions may pierce the frangible layer to create airways and allow air to escape from a vessel at a reduced velocity.
摘要翻译：在可储存和运输过程中，可以使用可刺破的盖子来容纳样品。可穿透帽可以防止在用传送装置转移之前样品样品的不必要的逸出。可刺破的帽可以装在船上。可穿透帽中的进入口可以允许传送装置的尖端通过可刺穿的帽。可以跨越进入端口设置易碎层。靠近易碎层的一个或多个延伸部可以通过联接区域或其它类似的装置连接到可刺穿的帽。一个或多个延伸部可以在传送装置的插入期间绕一个或多个耦合区域旋转。一个或多个延伸部的运动可以刺穿易碎层以形成气道并允许空气以较低的速度从容器中逸出。

3. 发明授权

US08058078B2 Device for automatically adjusting the bacterial inoculum level of a sample 有权
标题翻译：用于自动调节样品细菌接种量的装置
公开(公告)号：US08058078B2
公开(公告)日：2011-11-15
申请号：US13016040
申请日：2011-01-28
申请人： Timothy Hansen , Mark Anthony Messina , John Thuin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
发明人： Timothy Hansen , Mark Anthony Messina , John Thuin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
IPC分类号： G01N15/06 , G01N33/00 , G01N33/48
CPC分类号： G01N1/38 , C12M33/04 , G01N15/0205 , G01N35/0099 , G01N2035/00801 , G01N2035/1032 , Y10T436/11 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
摘要： Various embodiments of the present invention provide, for example, a system and method for automatically adjusting the inoculum level of a sample. Certain embodiments of the present invention may measure a concentration of particles present in a preliminary sample using a sensor device and determine an amount of diluent to be added to or removed from a sample container to prepare a sample having a selected concentration of particles, corresponding to a selected inoculum level. Embodiments of the present invention may also automatically add or remove the diluent using an automated fluidics system so as to prepare a sample having the selected particle concentration. Once the selected particle concentration is achieved and verified, some embodiments may also remove at least a portion of the sample from the sample container such that the container contains a selected volume of the sample.
摘要翻译：本发明的各种实施例提供了例如用于自动调节样品的接种物水平的系统和方法。本发明的某些实施方案可以使用传感器装置测量存在于初步样品中的颗粒的浓度，并且确定要添加到样品容器中或从样品容器移除的稀释剂的量以制备具有选定浓度的颗粒的样品，对应于选择接种量。本发明的实施方案还可以使用自动化流体系统自动添加或除去稀释剂，以制备具有所选择的颗粒浓度的样品。一旦获得并验证所选择的颗粒浓度，一些实施方案也可以从样品容器中去除样品的至少一部分，使得容器含有所选择的样品体积。

4. 发明申请

US20110123975A1 DEVICE FOR AUTOMATICALLY ADJUSTING THE BACTERIAL INOCULUM LEVEL OF A SAMPLE 有权
标题翻译：用于自动调节样品的细菌浓度的装置
公开(公告)号：US20110123975A1
公开(公告)日：2011-05-26
申请号：US13016040
申请日：2011-01-28
申请人： Timothy Roy Hansen , Mark Anthony Messina , John Thulin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
发明人： Timothy Roy Hansen , Mark Anthony Messina , John Thulin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
IPC分类号： C12Q3/00 , G06F19/00
CPC分类号： G01N1/38 , C12M33/04 , G01N15/0205 , G01N35/0099 , G01N2035/00801 , G01N2035/1032 , Y10T436/11 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
摘要： Various embodiments of the present invention provide, for example, a system and method for automatically adjusting the inoculum level of a sample. Certain embodiments of the present invention may measure a concentration of particles present in a preliminary sample using a sensor device and determine an amount of diluent to be added to or removed from a sample container to prepare a sample having a selected concentration of particles, corresponding to a selected inoculum level. Embodiments of the present invention may also automatically add or remove the diluent using an automated fluidics system so as to prepare a sample having the selected particle concentration. Once the selected particle concentration is achieved and verified, some embodiments may also remove at least a portion of the sample from the sample container such that the container contains a selected volume of the sample.
摘要翻译：本发明的各种实施例提供了例如用于自动调节样品的接种物水平的系统和方法。本发明的某些实施方案可以使用传感器装置测量存在于初步样品中的颗粒的浓度，并且确定要添加到样品容器中或从样品容器移除的稀释剂的量以制备具有选定浓度的颗粒的样品，对应于选择接种量。本发明的实施方案还可以使用自动化流体系统自动添加或除去稀释剂，以制备具有所选择的颗粒浓度的样品。一旦获得并验证所选择的颗粒浓度，一些实施方案也可以从样品容器中去除样品的至少一部分，使得容器含有所选择的样品体积。

5. 发明申请

US20080251489A1 Pierceable cap 有权
标题翻译：可穿帽子
公开(公告)号：US20080251489A1
公开(公告)日：2008-10-16
申请号：US11785144
申请日：2007-04-16
申请人： Dwight Livingston , Dustin Diemert , Ammon David Lentz
发明人： Dwight Livingston , Dustin Diemert , Ammon David Lentz
IPC分类号： B65D47/36 , B01L3/00 , B65D47/38
CPC分类号： B65D51/224 , B01L3/50825 , B01L2300/044 , B01L2300/0672 , B01L2400/0683
摘要： A pierceable cap may be used for containing sample specimens during storage and transport. The pierceable cap may prevent unwanted escape of sample specimen before transfer with a transfer device. The pierceable cap may fit over a vessel. An access port in the pierceable cap may allow passage of a tip of a transfer device though the pierceable cap. A frangible layer may be disposed across the access port. One or more extensions proximate to the frangible layer may be coupled to the pierceable cap by coupling regions or other similar devices. The one or more extension may rotate around the one or more coupling regions during insertion of the transfer device. The movement of the one or more extensions may pierce the frangible layer to create airways and allow air to escape from a vessel at a reduced velocity.
摘要翻译：在可储存和运输过程中，可以使用可刺破的盖子来容纳样品。可穿透帽可以防止在用传送装置转移之前样品样品的不必要的逸出。可刺破的帽可以装在船上。可穿透帽中的进入口可以允许传送装置的尖端通过可刺穿的帽。可以跨越进入端口设置易碎层。靠近易碎层的一个或多个延伸部可以通过联接区域或其它类似的装置连接到可刺穿的帽。一个或多个延伸部可以在传送装置的插入期间绕一个或多个耦合区域旋转。一个或多个延伸部的运动可以刺穿易碎层以形成气道并允许空气以较低的速度从容器中逸出。

6. 发明申请

US20080072664A1 DEVICE FOR AUTOMATICALLY ADJUSTING THE BACTERIAL INOCULUM LEVEL OF A SAMPLE 有权
标题翻译：用于自动调节样品的细菌浓度的装置
公开(公告)号：US20080072664A1
公开(公告)日：2008-03-27
申请号：US11691662
申请日：2007-03-27
申请人： Timothy Roy Hansen , John Thulin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
发明人： Timothy Roy Hansen , John Thulin Page , Thomas Paul Borgoyn , Ammon David Lentz , Robert Michael Novak
IPC分类号： G01N1/38 , B01L11/00 , G06F17/00
CPC分类号： G01N1/38 , C12M33/04 , G01N15/0205 , G01N35/0099 , G01N2035/00801 , G01N2035/1032 , Y10T436/11 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
摘要： Various embodiments of the present invention provide, for example, a system and method for automatically adjusting the inoculum level of a sample. Certain embodiments of the present invention may measure a concentration of particles present in a preliminary sample using a sensor device and determine an amount of diluent to be added to or removed from a sample container to prepare a sample having a selected concentration of particles, corresponding to a selected inoculum level. Embodiments of the present invention may also automatically add or remove the diluent using an automated fluidics system so as to prepare a sample having the selected particle concentration. Once the selected particle concentration is achieved and verified, some embodiments may also remove at least a portion of the sample from the sample container such that the container contains a selected volume of the sample.
摘要翻译：本发明的各种实施例提供了例如用于自动调节样品的接种物水平的系统和方法。本发明的某些实施方案可以使用传感器装置测量存在于初步样品中的颗粒的浓度，并且确定要添加到样品容器中或从样品容器移除的稀释剂的量以制备具有选定浓度的颗粒的样品，对应于选择接种量。本发明的实施方案还可以使用自动化流体系统自动添加或除去稀释剂，以制备具有所选择的颗粒浓度的样品。一旦获得并验证所选择的颗粒浓度，一些实施方案也可以从样品容器中去除样品的至少一部分，使得容器含有所选择的样品体积。

7. 发明申请

US20050288656A1 System for bi-directionally controlling the cryo-tip of a cryoablation catheter 失效
标题翻译：用于双向控制冷冻消融导管的低温尖端的系统
公开(公告)号：US20050288656A1
公开(公告)日：2005-12-29
申请号：US10876306
申请日：2004-06-24
申请人： Richard Koerner , David Lentz , Joseph O'Donnell , Alvin Salinas
发明人： Richard Koerner , David Lentz , Joseph O'Donnell , Alvin Salinas
IPC分类号： A61B17/00 , A61B18/02 , A61M31/00 , A61M37/00
CPC分类号： A61M25/0147 , A61B18/02 , A61B2017/003 , A61B2018/0212 , A61B2018/0262 , A61M25/0043 , A61M25/0136 , A61M25/0138 , A61M2025/0161
摘要： A bi-directional system for actively deflecting the distal tip of a catheter includes a reconfigurable tube that is positioned proximal to the catheter's distal tip. The tube is formed with slits that are arranged to allow the tube to be transformed from a relaxed, cylindrical configuration to a plurality of deflected configurations. First and second pull wires are provided, with each wire having a respective distal end that is attached to the distal end of the tube. Each wire extends to a catheter handle where it is attached to a respective reel. The reels can be rotated, back and forth, to selectively deflect or relax the tube. To ensure a smooth recovery after a relatively large deflection, a mechanism is disclosed for delaying an application of tension on one of the pull wires until at least a portion of any tension on the other pull wire is released.
摘要翻译：用于主动地偏转导管的远端的双向系统包括可重新配置的管，其位于导管的远端顶端附近。管形成有狭缝，狭缝被设置成允许管从松弛的圆柱形构型转变成多个偏转构型。提供第一和第二拉线，每条线具有附接到管的远端的相应远端。每根导线延伸到导管手柄，在其处连接到相应的卷轴上。卷轴可以来回旋转，以选择性地偏转或松弛管。为了确保在相对大的偏转之后的平稳恢复，公开了一种用于延迟在一条拉丝上施加张力的机构，直到另一拉线上的任何张力的至少一部分被释放。

8. 发明申请

US20050288626A1 Active system for deflecting a distal portion of a catheter into a hoop configuration 有权
标题翻译：用于将导管的远端部分偏转成环形构造的主动系统
公开(公告)号：US20050288626A1
公开(公告)日：2005-12-29
申请号：US10876312
申请日：2004-06-24
申请人： Richard Koerner , David Lentz , Joseph O'Donnell
发明人： Richard Koerner , David Lentz , Joseph O'Donnell
IPC分类号： A61B18/02 , A61M25/01 , A61M31/00
CPC分类号： A61M25/0147 , A61B2017/003 , A61B2018/0212 , A61B2018/0231 , A61B2018/0262 , A61M25/0136 , A61M2025/0161
摘要： An active system for deflecting a distal portion of a catheter into a hoop configuration includes an elongated catheter body having a proximal portion and a distal portion that is formed with a lumen. A thin-walled tube, which is typically made of a metallic material, is positioned in the lumen. The tube includes a cylindrical wall and includes a plurality of lateral slits that are typically formed in the tube wall and arranged such that the tube can be transformed between a relaxed, cylindrical configuration and a deflected configuration wherein the tube is substantially hoop shaped. One end of a deflection wire is attached to the tube and the other wire end is attached to a reel that is rotationally mounted onto a catheter handle housing. In use, the reel is rotated to axially retract the wire and transform the tube into a hoop configuration.
摘要翻译：用于将导管的远侧部分偏转成环形构造的主动系统包括具有近端部分和形成有内腔的远侧部分的细长导管主体。通常由金属材料制成的薄壁管被定位在内腔中。管包括圆柱形壁并且包括多个横向狭缝，其通常形成在管壁中并且布置成使得管可以在松弛的圆柱形构造和偏转构造之间变形，其中管基本上是环形的。偏转线的一端附接到管，另一个线端附接到旋转地安装到导管手柄壳体上的卷轴上。在使用中，卷轴旋转以轴线缩回线，并将管转变成环箍构型。

9. 发明申请

US20050283179A1 Introducer sheath 审中-公开
标题翻译：导引鞘
公开(公告)号：US20050283179A1
公开(公告)日：2005-12-22
申请号：US10869996
申请日：2004-06-17
申请人： David Lentz
发明人： David Lentz
IPC分类号： A61F2/958 , A61M25/00 , A61M25/06 , A61M29/00
CPC分类号： A61M25/0662 , A61M25/0054 , A61M25/10
摘要： An introducer sheath includes an elongated hollow hypotube that is formed with a spiral cut that extends between the ends of the hypotube and extends through the hypotube from its outer surface to its inner surface. During manufacture, the spiral cut is made with a pitch angle (α) that can be varied along the length of the hypotube to provide different sections of the hypotube with different degrees of flexibility. A polymer coating is positioned on the outer surface of the hypotube to establish a lubricious coating for the introducer sheath.
摘要翻译：引导器护套包括细长的中空海波波形管，其形成有在海波波的端部之间延伸的螺旋形切口，并从海波波的外表面延伸到其内表面。在制造过程中，螺旋切割采用可以沿海波波长度变化的俯仰角（α），以提供不同程度的柔度的海波管的不同部分。聚合物涂层定位在海波管的外表面上，以为引导器护套建立光滑的涂层。

10. 发明申请

US20050177131A1 Catheter articulation segment with alternating cuts 审中-公开
标题翻译：导管交叉节段交替切割
公开(公告)号：US20050177131A1
公开(公告)日：2005-08-11
申请号：US10774665
申请日：2004-02-09
申请人： David Lentz , Richard Koerner
发明人： David Lentz , Richard Koerner
IPC分类号： A61M25/00
CPC分类号： A61M25/0013 , A61M25/0054 , A61M25/0138
摘要： An articulation segment for a catheter includes a tube formed with a first plurality of axially aligned slits that are respectively oriented in planes perpendicular to the axis, with each slit extending azimuthally in an arc partway around the axis. The tube is also formed with a second plurality of similarly formed slits that are axially offset and diametrically opposed relative to the slits of the first plurality to allow for a bending of the catheter in a plurality of different planes.
摘要翻译：用于导管的关节节段包括形成有第一多个轴向对准的狭缝的管，其分别定向在垂直于轴线的平面中，每个狭缝围绕轴线在一半弧中方位延伸。管还形成有第二多个类似形成的狭缝，其相对于第一多个的狭缝轴向地偏置并沿直径相对，以允许导管在多个不同平面中弯曲。

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