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1. 发明申请

US20130098137A1 TONOMETER CALIBRATION TOOL 有权
标题翻译： TONOMETER校准工具
公开(公告)号：US20130098137A1
公开(公告)日：2013-04-25
申请号：US13278214
申请日：2011-10-21
申请人： Russell Bonaventura , David G. Kelkenberg , David L. Beverly , Donald E. Miller , David A. Luce
发明人： Russell Bonaventura , David G. Kelkenberg , David L. Beverly , Donald E. Miller , David A. Luce
IPC分类号： G01L27/00
CPC分类号： A61B3/165 , G01L27/002
摘要： A tool for calibrating a non-contact tonometer (NCT) comprises a body having a mating feature configured for removably mounting the body on the nosepiece or on the measurement head of the NCT, a pressure sensor carried by the body and arranged to receive an air pulse discharged by the NCT to provide a pressure signal in response to the air pulse, and a radiation emitter carried by the body, wherein the radiation emitter provides a pseudo-applanation event when the pressure signal reaches a predetermined level that is detectable by the NCT as though an actual corneal applanation had taken place. In one embodiment, the mating feature includes a mounting orifice for receiving a portion of the nosepiece. In another embodiment, the mating feature includes a pair of mounting pins sized for receipt by a corresponding pair of mounting holes in the measurement head of the NCT.
摘要翻译：用于校准非接触式眼压计（NCT）的工具包括具有配置特征的主体，该配合特征被配置为将主体可拆卸地安装在鼻甲管或NCT的测量头上，压力传感器由主体承载并布置成接收空气由NCT放电的脉冲以响应于空气脉冲提供压力信号，以及由身体携带的辐射发射器，其中当压力信号达到可被NCT检测到的预定水平时，辐射发射器提供假压平事件好像发生了一个实际的角膜压迫。在一个实施例中，配合特征包括用于接收鼻梁的一部分的安装孔。在另一个实施例中，配合特征包括一对安装销，其尺寸适于由NCT的测量头中的相应的一对安装孔接收。

2. 发明申请

US20120190961A1 SUBSYSTEMS AND METHODS FOR NON-CONTACT CORNEAL DEFORMATION 有权
标题翻译：非接触角度变形的子系统和方法
公开(公告)号：US20120190961A1
公开(公告)日：2012-07-26
申请号：US13013102
申请日：2011-01-25
申请人： David A. Luce
发明人： David A. Luce
IPC分类号： A61B3/16
CPC分类号： A61B3/165
摘要： An ophthalmic instrument that discharges a fluid pulse to deform the cornea of a test subject is improved by reducing the working distance between a nosepiece or a discharge tube from which the fluid pulse is discharged and the eye of the test subject. The invention improves measurement repeatability and patient comfort.
摘要翻译：通过减少流体脉冲被排出的鼻梁或放电管与受试者的眼睛之间的工作距离，可以改善排出流体脉冲以使测试对象的角膜变形的眼科仪器。本发明提高了测量重复性和患者舒适度。

3. 发明申请

US20110245649A1 Ophthalmic Diagnostic Instrument And Method 有权
标题翻译：眼科诊断仪器及方法
公开(公告)号：US20110245649A1
公开(公告)日：2011-10-06
申请号：US12751281
申请日：2010-03-31
申请人： David A. Luce
发明人： David A. Luce
IPC分类号： A61B3/16
CPC分类号： A61B3/165 , A61B3/0025
摘要： In an ophthalmic instrument that directs a fluid pulse at a cornea to cause reversible deformation of the cornea and monitors the corneal deformation to generate a deformation signal, the shape of the deformation signal is analyzed with respect to deformation signal data from a statistical population of eyes to calculate a deformation signal score indicating a degree of probability that the deformation signal corresponds in shape to a normal deformation signal for normal eyes in the population. In calculating the deformation signal score, significant geometrical signal parameters are calculated and combined. The deformation signal score may be used as a basis to keep or discard intraocular pressure measurements in a non-contact tonometer, and/or as a basis to conduct further diagnostic screening.
摘要翻译：在眼科仪器中，指示角膜上的流体脉冲引起角膜的可逆变形并监测角膜变形以产生变形信号，相对于来自统计学上的眼睛的变形信号数据分析变形信号的形状计算出变形信号得分，其表示变形信号的形状对于群体中正常眼睛的正常变形信号的概率。在计算变形信号得分时，计算并组合了重要的几何信号参数。变形信号得分可以用作在非接触眼压计中保持或丢弃眼压测量的基础，和/或作为进一步诊断筛查的基础。

4. 发明授权

US07798962B2 Method and apparatus for measuring corneal resistance 有权
标题翻译：测量角膜抵抗力的方法和装置
公开(公告)号：US07798962B2
公开(公告)日：2010-09-21
申请号：US11222132
申请日：2005-09-08
申请人： David A. Luce
发明人： David A. Luce
IPC分类号： A61B3/16 , A61B13/00 , A61B5/103 , A61B5/117 , A61B3/00 , A61B3/10 , A61B3/14
CPC分类号： A61B3/16 , A61B3/1005
摘要： A method and apparatus for measuring corneal resistance to deformation use an empirically derived function wherein an inward applanation pressure P1 and an outward applanation pressure P2 obtained during a corneal deformation cycle caused by a fluid pulse are separately weighted so as to minimize dependence of the calculated corneal resistance factor (CRF) on intraocular pressure. In one embodiment, the function is optimized, at least in part, to maximize statistical correlation between the calculated corneal resistance factor (CRF) and central corneal thickness.
摘要翻译：用于测量变形抗角膜变形的方法和装置使用经验导出的功能，其中在由流体脉冲引起的角膜变形循环期间获得的向内压平压力P1和向外压扁压力P2被分别加权，以便使所计算的角膜的依赖性最小化阻力因子（CRF）对眼压的影响。在一个实施例中，该功能至少部分地被优化，以最大化计算的角膜电阻因子（CRF）和中心角膜厚度之间的统计学相关性。

5. 发明授权

US07481767B2 Method and apparatus for determining true intraocular pressure 有权
标题翻译：用于确定真实眼内压的方法和装置
公开(公告)号：US07481767B2
公开(公告)日：2009-01-27
申请号：US11222166
申请日：2005-09-08
申请人： David A. Luce
发明人： David A. Luce
IPC分类号： A61B3/16
CPC分类号： A61B3/165
摘要： A method and apparatus for measuring intraocular pressure of an eye use an empirically derived function wherein an inward applanation pressure P1 and an outward applanation pressure P2 obtained during a corneal deformation cycle caused by a fluid pulse are separately weighted so as to minimize cornea-related influence on the intraocular pressure value calculated by the function. In one embodiment, the function is optimized, at least in part, to minimize change in calculated IOP between measurements made before surgical alteration of the cornea and measurements made after surgical alteration of the cornea.
摘要翻译：用于测量眼睛眼压的方法和装置使用经验导出的功能，其中在由流体脉冲引起的角膜变形循环期间获得的向内压迫压力P1和向外压迫压力P2被分别加权，以便最小化与角膜相关的影响对由功能计算出的眼内压值。在一个实施例中，该功能被优化，至少部分地最小化在角膜手术改变之前进行的测量和角膜手术改变后进行的测量之间的计算IOP的变化。

6. 发明授权

US06419631B1 Non-contact tonometry method 有权
标题翻译：非接触式眼压测定法
公开(公告)号：US06419631B1
公开(公告)日：2002-07-16
申请号：US09553111
申请日：2000-04-20
申请人： David A. Luce
发明人： David A. Luce
IPC分类号： A61B500
CPC分类号： A61B3/165
摘要： During corneal deformation induced by a fluid pulse, observations associated with an inward first state of applanation and an outward second state of applanation are processed to provide a final reported intra-ocular pressure value that is substantially without error due to corneal thickness effects.
摘要翻译：在由流体脉冲引起的角膜变形期间，处理与向内的第一压迫状态和挤压的外部第二状态相关联的观察，以提供由于角膜厚度效应基本上没有误差的最终报告的眼内压力值。

7. 发明授权

US6042232A Automatic optometer evaluation method using data over a wide range of focusing positions 失效
标题翻译：自动光度计评估方法使用数据在广泛的聚焦位置
公开(公告)号：US6042232A
公开(公告)日：2000-03-28
申请号：US234723
申请日：1999-01-21
申请人： David A. Luce , Matthew Severns
发明人： David A. Luce , Matthew Severns
IPC分类号： A61B3/10 , A61B3/103
CPC分类号： A61B3/103
摘要： A method and apparatus for measuring refractive properties of a refractive optical system by fitting measurement data points to a derived function are disclosed. In a preferred embodiment relating to an automatic objective optometer, each data point represents a peak signal amplitude extracted from a scan of a plurality of pixels on an area detector array receiving light from the illuminated refractive optical system at a particular optometer position. The derived function describes a relationship between the peak pixel signal and optometer position based on changing focusing conditions of light at the detector array, which correspond to focusing conditions at an image plane of the refractive optical system under a confocal arrangement. A first derived function is applied for fast and slow sphere optometer sweeps through broad and refined ranges and includes a pair of poles at first and second astigmatic focal points to give the magnitude of sphere and cylinder powers of the eye, and a second derived function is applied for a cylinder sweep varying the axis of a non-zero cylinder component introduced to the illuminating light and includes a single pole for giving the cylinder axis.
摘要翻译：公开了一种通过将测量数据点拟合到导出函数来测量折射光学系统的折射特性的方法和装置。在涉及自动目标光学计量器的优选实施例中，每个数据点表示从区域检测器阵列上的多个像素的扫描中提取的峰值信号振幅，该区域检测器阵列在特定的光度计位置处接收来自被照射的折射光学系统的光。衍生函数描述了基于在共焦排列处对应于折射光学系统的像面处的聚焦条件的检测器阵列处的光的聚焦条件改变的峰值像素信号和光度计位置之间的关系。第一个导出函数被应用于快速和慢速的球形光谱仪扫描广泛和精细的范围，并且包括在第一和第二散光焦点处的一对极点，以给出眼睛的球体和圆柱体功率的大小，并且第二导出函数是应用于改变引入照明光的非零气缸分量的轴线的气缸扫描，并且包括用于给出气缸轴线的单极。

8. 发明授权

US5754273A Non-contact tonometer having off-axis fluid pulse system 失效
标题翻译：非接触式眼压计具有离轴流体脉冲系统
公开(公告)号：US5754273A
公开(公告)日：1998-05-19
申请号：US804004
申请日：1997-02-21
申请人： David A. Luce
发明人： David A. Luce
IPC分类号： A61B3/16 , A61B3/10
CPC分类号： A61B3/165
摘要： A non-contact tonometer includes a fixation axis intersecting the corneal vertex, and a fluid axis angularly displaced from the fixation axis to form a non-zero angle therewith. A nozzle is axially aligned along the fluid axis for discharging a fluid pulse along the fluid axis to the corneal surface of the eye. In a preferred embodiment, the fixation and fluid axes reside in the same vertical plane, with the fluid axis below the fixation axis approaching the eye. Alignment and applanation detection optics are arranged coplanar with the fluid axis.
摘要翻译：非接触式眼压计包括与角膜顶点相交的固定轴和与固定轴成角度地偏离以与其形成非零角度的流体轴。喷嘴沿着流体轴线轴向对齐，用于将沿着流体轴线的流体脉冲排放到眼睛的角膜表面。在优选实施例中，固定和流体轴线位于相同的垂直平面中，流体轴线在固定轴线下方接近眼睛。对准和压平检测光学器件与流体轴线共面布置。

9. 发明授权

US5446274A Instructive display for assisting in centering an optical path element on a path 失效
标题翻译：辅助显示器，用于协助路径上的光路元件居中
公开(公告)号：US5446274A
公开(公告)日：1995-08-29
申请号：US199703
申请日：1994-02-22
申请人： David A. Luce , Christopher J. Percival
发明人： David A. Luce , Christopher J. Percival
IPC分类号： G01J1/04 , A61B3/15 , G01M11/00 , G01M11/02 , G01J1/20
CPC分类号： A61B3/152 , G01M11/0221
摘要： A polar or vector display provides an operator of an optical instrument with a symbolic instruction regarding the direction and amount of motion required to center an optical element on a chosen path.
摘要翻译：极性或矢量显示为光学仪器的操作者提供关于使所选择的路径上的光学元件居中所需的运动的方向和量的符号指令。

10. 发明授权

US4881807A Optical alignment system 失效
标题翻译：光学校准系统
公开(公告)号：US4881807A
公开(公告)日：1989-11-21
申请号：US228482
申请日：1988-08-05
申请人： David A. Luce , Srdjan Krstanovic
发明人： David A. Luce , Srdjan Krstanovic
IPC分类号： A61B3/10 , A61B3/00 , A61B3/107 , A61B3/16
CPC分类号： A61B3/165 , A61B3/0075 , A61B3/107
摘要： An optical alignment system using at least one CCD array for positioning an instrument in a chosen relationship to an object is disclosed. Means for "electronically" aligning the optical components and providing a macro view of the object on a CRT without additional illumination are also disclosed. Alignment may be achieved manually, if the operator observes the position of symbols on a CRT that move in response to movement of the instrument by the operator using a joystick, or automatically using information provided by the array.

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