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1. 发明授权

US06719689B2 Method and system for compressing and storing data in a medical device having limited storage 有权
标题翻译：用于在具有有限存储的医疗装置中压缩和存储数据的方法和系统
公开(公告)号：US06719689B2
公开(公告)日：2004-04-13
申请号：US09847049
申请日：2001-04-30
申请人： Dave Munneke , Harry B. A. Kerver
发明人： Dave Munneke , Harry B. A. Kerver
IPC分类号： A61B504
CPC分类号： A61B5/04325 , A61B5/7232 , G06F19/00
摘要： A method for compressing data in an implantable device is provided. A current data sample is received. A difference value is determined between the current data sample and a previous data sample. The current data sample is compressed to at least one output symbol based on the difference value between the current sample and the previous data sample. Systems and programs of using the method are also provided.
摘要翻译：提供了一种用于在可植入装置中压缩数据的方法。接收当前数据样本。在当前数据样本和先前的数据样本之间确定差值。基于当前样本和先前数据样本之间的差值，将当前数据样本压缩到至少一个输出符号。还提供了使用该方法的系统和程序。

2. 发明授权

US06745076B2 Implantable medical device with autosensitivity algorithm for controlling sensing of cardiac signals 有权
标题翻译：具有自动感应算法的植入式医疗器械用于控制心脏信号的感测
公开(公告)号：US06745076B2
公开(公告)日：2004-06-01
申请号：US09987777
申请日：2001-11-16
申请人： Peter Wohlgemuth , Henk A. Westendorp , Harry W. M. De Bruyn , J. Dave Munneke
发明人： Peter Wohlgemuth , Henk A. Westendorp , Harry W. M. De Bruyn , J. Dave Munneke
IPC分类号： A61N1362
CPC分类号： A61N1/3704 , A61N1/3718
摘要： A cardiac pacing system and method incorporate DSP processing and software algorithms for collecting signal amplitude data and noise data, and organizing the data for automatic checking of signal channel gain and signal detection sensitivity. Unfiltered signals are used to obtain values representative of maximum amplitude, which values are stored in a gain histogram, from which determination of the percentage of clipped signals can be made. Gain is adjusted by limiting clipping to a predetermined range of allowed clipping, to optimize use of the DSP range. The signals, both P waves and R waves for a dual chamber system, are also processed by DSP and parameters representing maximum amplitudes are stored in amplitude histograms. At the same time, noise is analyzed for respective windows of time following each ventricular event, and noise amplitude data is stored in noise histograms. After a predetermined waiting period, the signal amplitude and noise histograms are analyzed and compared, and for each channel the sensitivity is adjusted to fall between a calculated noise floor and the lowest bin of the amplitude histogram that contains valid data.
摘要翻译：心脏起搏系统和方法结合DSP处理和软件算法，用于收集信号幅度数据和噪声数据，并组织数据以自动检查信号通道增益和信号检测灵敏度。使用未滤波的信号来获得表示最大幅度的值，该值被存储在增益直方图中，从而可以确定限幅信号的百分比。通过将削波限制到允许限幅的预定范围来调整增益，以优化DSP范围的使用。双室系统的P波和R波信号也由DSP处理，表示最大振幅的参数存储在振幅直方图中。同时，针对每个心室事件之后的各个窗口分析噪声，噪声幅度数据被存储在噪声直方图中。在预定的等待周期之后，分析和比较信号幅度和噪声直方图，并且对于每个通道，灵敏度被调整为落在计算的本底噪声和包含有效数据的幅度直方图的最小二进制位之间。

3. 发明授权

US06434426B1 Method and system for determining a noise floor in a cardiac pacing system 失效
标题翻译：用于确定心脏起搏系统中的基底噪声的方法和系统
公开(公告)号：US06434426B1
公开(公告)日：2002-08-13
申请号：US09559052
申请日：2000-04-27
申请人： Jacob Dave Munneke , Peter W. Wohlgemuth , Harry W. M. De Bruyn , Anton L. Huijnen
发明人： Jacob Dave Munneke , Peter W. Wohlgemuth , Harry W. M. De Bruyn , Anton L. Huijnen
IPC分类号： A61N137
CPC分类号： A61N1/3956 , A61N1/3704 , A61N1/3925 , Y10S128/901
摘要： A method for determining a representative noise floor in a cardiac pacing system from which future events are measured is provided. An event amplitude is determined. Pluralities of noise levels are recorded, when each of the plurality of noise levels is less than a predetermined percentage of the event amplitude. The noise floor is determined as an absolute maximum value of the plurality of recorded noise levels.
摘要翻译：提供了一种用于确定心脏起搏系统中的代表性噪声基底的方法，其中测量未来事件。确定事件幅度。当多个噪声电平中的每一个小于事件幅度的预定百分比时，记录多个噪声电平。噪声本底被确定为多个记录噪声电平的绝对最大值。

4. 发明授权

US06556859B1 System and method for classifying sensed atrial events in a cardiac pacing system 有权
标题翻译：在心脏起搏系统中分类感觉到的心房事件的系统和方法
公开(公告)号：US06556859B1
公开(公告)日：2003-04-29
申请号：US09556663
申请日：2000-04-24
申请人： Peter W. Wohlgemuth , Dave Munneke , Gustaaf Stoop , Henk Westendorp , Mattias Rouw
发明人： Peter W. Wohlgemuth , Dave Munneke , Gustaaf Stoop , Henk Westendorp , Mattias Rouw
IPC分类号： A61B50452
CPC分类号： A61N1/362 , A61N1/3622 , A61N1/3704 , A61N1/3956
摘要： A system for a method of classifying distinct signals sensed from an electrode of an implantable cardiac pacing system positioned within an atrium of a heart of a patient is disclosed. The cardiac pacing system includes a pulse generator for generating pacing pulses and a controller for controlling the operation of a pacemaker. The method includes collecting atrial event signals consisting of P-wave signals and far field R-wave signals. An interim form factor histogram is generated based upon a form of collected atrial event signals. The interim form factor histogram includes an interim P-wave form factor histogram and an interim far field R-wave form factor histogram, each having bins of atrial event signals. A previously generated form factor histogram is weighted and combined with the interim form factor histogram to create a representative form factor histogram. The representative form factor histogram is analyzed to determine if a minimal safety margin is located between the representative P-wave form factor histogram and the representative far field R-wave form factor histogram. Atrial event signals are classified by form as either P-wave signals or far field R-wave signals based upon the representative form factor histogram.
摘要翻译：公开了一种用于分类从位于患者心脏的心房内的可植入心脏起搏系统的电极感测到的不同信号的方法的系统。心脏起搏系统包括用于产生起搏脉冲的脉冲发生器和用于控制起搏器操作的控制器。该方法包括收集由P波信号和远场R波信号组成的心房事件信号。基于收集的心房事件信号的形式生成临时形状因子直方图。临时形状因子直方图包括临时P波形状因子直方图和临时远场R波形形状因子直方图，每个都具有心房事件信号。将先前生成的形状因子直方图加权并与临时形状因子直方图组合以创建代表性的形状因子直方图。分析代表性形状因子直方图以确定代表性的P波形状因子直方图与代表性的远场R波形形状因子直方图之间是否存在最小安全裕度。基于代表性的形状因子直方图，心房事件信号通过形式分类为P波信号或远场R波信号。

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