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1. 发明授权

US09638769B2 Position marker for use in an MRI apparatus 有权
公开(公告)号：US09638769B2
公开(公告)日：2017-05-02
申请号：US14233811
申请日：2012-07-16
申请人： Daniel Wirtz , Christoph Leussler , Sascha Krueger
发明人： Daniel Wirtz , Christoph Leussler , Sascha Krueger
IPC分类号： G01V3/00 , G01R33/28 , G01R33/58
CPC分类号： G01R33/28 , G01R33/287 , G01R33/58
摘要： A fiducial position marker (1) for use in a magnetic resonance (MR) imaging apparatus is disclosed for exciting and/or receiving MR signals in/from a local volume which at least substantially surrounds or adjoins the position marker, in order to determine and/or image from these MR signals the position of the position marker in an MR image of an examination object. Such a position marker (1) is especially used for determining and/or imaging a position of an interventional or non-interventional instrument to which the position marker may be attached, like a catheter, a surgical device, a biopsy needle, a pointer, a stent or another invasive or any non-invasive device in an MR image of an examination object. Further, a position marker system comprising such a position marker (1) and a circuit arrangement (5, 6, 6a, 8) for driving the position marker (1) for exciting MR signals and/or for processing MR signals received by the position marker is disclosed.

2. 发明申请

US20120169340A1 MR IMAGING SYSTEM WITH FREELY ACCESSIBLE EXAMINATION VOLUME 审中-公开
标题翻译：具有可访问量的成像系统
公开(公告)号：US20120169340A1
公开(公告)日：2012-07-05
申请号：US13394969
申请日：2010-09-14
申请人： Christoph Leussler , Daniel Wirtz
发明人： Christoph Leussler , Daniel Wirtz
IPC分类号： G01R33/48 , G01R33/32
CPC分类号： G01R33/345 , G01R33/341 , G01R33/343 , G01R33/4802
摘要： The invention relates to a magnetic resonance imaging system (1) comprising: a main magnet for generating a uniform, steady magnetic field within an examination volume (21), an RF waveguide (19) for guiding travelling RF waves along an axis of the examination volume (21) in at least one travelling mode of the RF waveguide (19), at least one RF antenna (9) for transmitting RF pulses to and/or receiving MR signals from a body (10) of a patient positioned in the examination volume (21), wherein the RF antenna (9) is configured to couple to the at least one travelling mode of the RF waveguide (19), and wherein the RF antenna (9) is located on the imaging system such that the examination volume (21) is freely accessible, a control unit (15) for controlling the temporal succession of RF pulses, and a reconstruction unit (17) for reconstructing an MR image from the received MR signals. Further, the invention relates to an RF antenna (9) for an MR imaging system (1), wherein the RF antenna (9) is formed by an electrically conductive plate (22) comprising at least one recess (23).
摘要翻译：本发明涉及一种磁共振成像系统（1），包括：用于在检查体积（21）内产生均匀的稳定磁场的主磁体，用于沿检查轴引导行波RF波的RF波导（19）在RF波导（19）的至少一个行进模式中的体积（21），用于将RF脉冲发送到和/或接收来自位于检查中的患者的身体（10）的MR信号的至少一个RF天线（9）（21），其中所述RF天线（9）被配置为耦合到所述RF波导（19）的所述至少一个行进模式，并且其中所述RF天线（9）位于所述成像系统上，使得所述检查体积（21）可自由访问，用于控制RF脉冲的时间连续的控制单元（15），以及用于从所接收的MR信号重建MR图像的重建单元（17）。此外，本发明涉及一种用于MR成像系统（1）的RF天线（9），其中RF天线（9）由包括至少一个凹部（23）的导电板（22）形成。

3. 发明申请

US20100181109A1 TRANSMISSION CABLE FOR USE IN RADIO-FREQUENCY MAGNETIC OR ELECTRICAL FIELDS 有权
标题翻译：用于无线电频率电磁场的变速电缆
公开(公告)号：US20100181109A1
公开(公告)日：2010-07-22
申请号：US12665947
申请日：2008-06-27
申请人： Sascha Krueger , Bernd David , Oliver Lips , Steffen Weiss , Daniel Wirtz
发明人： Sascha Krueger , Bernd David , Oliver Lips , Steffen Weiss , Daniel Wirtz
IPC分类号： H01B7/00
CPC分类号： G01R33/36 , A61B18/14 , A61B2018/00178 , A61B2090/374 , A61N1/086 , G01R33/287 , G01R33/288 , G01R33/3664
摘要： A transmission cable for use in an elongate medical device (420) such as a catheter, guide wire, etc., wherein the transmission cable is capable of being switched to an MR-safe mode only when necessary, while retaining its optimal electrical transmission properties otherwise, is disclosed herein. The transmission cable comprises a transmission line including at least two electrically conductive line segments (104a, 104b) separated by a non-conductive gap (106a), a bridging unit comprising at least one electrically conductive bridge segment (108a) capable of bridging the non-conductive gap, and a switching unit (112) arranged to move the bridging unit and/or the transmission line to electrically connect the two line segments by closing the non-conductive gap using the bridge segment or to electrically disconnect the two line segments by opening the non-conductive gap.
摘要翻译：一种用于诸如导管，导丝等细长医疗设备（420）的传输电缆，其中传输电缆仅在必要时能够切换到MR安全模式，同时保持其最佳电气传输特性否则，在此公开。传输电缆包括传输线，传输线包括由非导电间隙（106a）隔开的至少两个导电线段（104a，104b）;桥接单元，包括至少一个导电桥段（108a）以及开关单元（112），其布置成使桥接单元和/或传输线移动以通过使用桥接段闭合非导电间隙来电连接两个线段，或者通过打开非导电间隙。

4. 发明申请

US20100060283A1 DETUNING A RADIO-FREQUENCY COIL 有权
标题翻译：清除无线电频率线圈
公开(公告)号：US20100060283A1
公开(公告)日：2010-03-11
申请号：US12302354
申请日：2007-05-29
申请人： Christian FINDEKLEE , Daniel WIRTZ
发明人： Christian FINDEKLEE , Daniel WIRTZ
IPC分类号： G01R33/44
CPC分类号： G01R33/34046 , G01R33/34007 , G01R33/345 , G01R33/3453 , G01R33/3635 , G01R33/3657
摘要： For detuning of radio-frequency coils (in magnetic resonance imaging and spectroscopy, for example), a conducting element (102) of a transmission cable is configured to form a primary resonant circuit tunable to at least one first resonance frequency. A second conducting element (104) of the transmission cable is configured to form a switching circuit that is electrically insulated from and reactively coupled via inductive coupling and/or capacitive coupling to the primary resonant circuit, and is adapted to tune the primary resonant circuit to at least one second resonance frequency, thereby detuning the primary resonant circuit.
摘要翻译：对于射频线圈的失谐（例如在磁共振成像和光谱学中），传输电缆的导电元件（102）被配置为形成可调谐至少一个第一共振频率的主谐振电路。传输电缆的第二导电元件（104）被配置为形成开关电路，该开关电路通过电感耦合和/或电容耦合与主谐振电路电绝缘并且通过其反应耦合，并且适于将主谐振电路调谐到至少一个第二谐振频率，从而使主谐振电路失谐。

5. 发明申请

US20100041977A1 CATHETER AND MEDICAL ASSEMBLY 有权
标题翻译：导管和医疗装置
公开(公告)号：US20100041977A1
公开(公告)日：2010-02-18
申请号：US12440252
申请日：2007-09-07
申请人： Oliver Lips , Bernd David , Bernhard Gleich , Sascha Krueger , Steffen Weiss , Daniel Wirtz
发明人： Oliver Lips , Bernd David , Bernhard Gleich , Sascha Krueger , Steffen Weiss , Daniel Wirtz
IPC分类号： A61N1/375 , A61B5/0408 , A61B5/055
CPC分类号： A61B5/042 , A61B5/0428 , A61B5/055 , A61B2562/222 , A61N1/056 , A61N1/086 , A61N1/3625 , A61N1/3718 , G01R33/287
摘要： The present invention relates to a catheter (6) comprising: a connector (65, 66) at a proximal side of the catheter for connecting the catheter to an external signal transmission/receiving unit (10) for transmitting and/or receiving signals, an electrode (63, 64) at a distal side of the catheter, and an electrical connection including an electrical wire (61, 62) for electrically connecting the electrode and the connector for the transmission of signals between the electrode and the connector, wherein the electrical connection has a high electrical resistance of at least 1 kΩ, in particular of at least 5 kΩ. Thus, the present invention provides a solution to prevent excessive heating during EP interventions under MR guidance by using by using highly resistive wires and or lumped resistors as connections within catheters.
摘要翻译：本发明涉及一种导管（6），包括：在导管的近侧的连接器（65,66），用于将导管连接到用于传输和/或接收信号的外部信号传输/接收单元（10），电极（63,64），以及包括用于电连接电极和连接器以用于在电极和连接器之间传输信号的电线（61,62）的电连接，其中电气连接具有至少1kΩ和OHgr的高电阻，特别是至少5kΩ。因此，本发明提供了一种用于在MR引导下的EP干预期间通过使用高电阻丝和/或集中电阻器作为导管内的连接使用来防止过度加热的解决方案。

6. 发明申请

US20100013484A1 TRANSMISSION LINE FOR USE IN MAGNETIC RESONANCE SYSTEM 有权
标题翻译：用于磁共振系统的传输线
公开(公告)号：US20100013484A1
公开(公告)日：2010-01-21
申请号：US12520182
申请日：2007-12-20
申请人： Daniel Wirtz , Oliver Lips , Sascha Krueger , Bernd David , Steffen Weiss
发明人： Daniel Wirtz , Oliver Lips , Sascha Krueger , Bernd David , Steffen Weiss
IPC分类号： G01R33/44
CPC分类号： G01R33/287 , G01R33/288
摘要： An electrically conductive transmission cable for supplying a DC signal safely to an electrical device in the presence of radio-frequency (RF) fields in a magnetic resonance (MR) is disclosed herein. The transmission cable comprises a transmission line (STL) comprising at least a first segment (S1) and a second segment (S2), wherein the first and second segments are electrically connected to each other by a reactive coupling unit (103), and a rectifier unit (101) connected to the transmission line and configured to extract the DC signal (203) from the modulated DC signal (201). The extracted DC signal may be supplied to an electrical device or used for cardiac pacing. The transmission cable finds application in auxiliary devices used in an MR environment, for example an interventional catheter with or without an active tracking circuit (301).
摘要翻译：本文公开了一种用于在磁共振（MR）中存在射频（RF）场的情况下将DC信号安全地提供给电气设备的导电传输电缆。传输电缆包括至少包括第一段（S1）和第二段（S2）的传输线（STL），其中第一和第二段通过无功耦合单元（103）彼此电连接，并且整流单元（101），连接到所述传输线并且被配置为从所述调制的DC信号（201）提取所述DC信号（203）。所提取的DC信号可以被提供给电气设备或用于心脏起搏。传输电缆可用于在MR环境中使用的辅助设备中，例如具有或不具有主动跟踪电路（301）的介入导管。

7. 发明申请

US20090206840A1 MAGNETIC RESONANCE RECEIVE COIL ARRAY INTEGRATED INTO WALL OF SCANNER BORE 审中-公开
标题翻译：磁共振接收线圈阵列集成到扫描器的壁上
公开(公告)号：US20090206840A1
公开(公告)日：2009-08-20
申请号：US12305442
申请日：2007-06-19
申请人： Johan A. Overweg , Daniel Wirtz
发明人： Johan A. Overweg , Daniel Wirtz
IPC分类号： G01R33/36
CPC分类号： G01R33/341 , G01R33/3415 , G01R33/3621 , G01R33/3642 , G01R33/3657
摘要： In a magnetic resonance scanner, a radio frequency transmit coil (30, 30′) includes a plurality of parallel rods rungs (32, 32′, 32″) at least partially surrounding an examination region. The radio frequency transmit coil is configured to transmit radio frequency energy into the examination region at or near a magnetic resonance frequency. A plurality of magnetic resonance receive coils (40) are disposed with the radio frequency transmit coil. For decoupling, each magnetic resonance receive coil is positioned substantially centered on a proximate one rod or rung or proximate plurality of neighboring rods or rungs of the radio frequency transmit coil.
摘要翻译：在磁共振扫描器中，射频发射线圈（30,30'）包括至少部分地围绕检查区域的多个平行杆梯级（32,32'，32“）。射频发射线圈被配置为在磁谐振频率处或接近磁共振频率处将射频能量传送到检查区域。多个磁共振接收线圈（40）与射频发射线圈配置。为了解耦，每个磁共振接收线圈基本上定位在射频发射线圈的邻近的一个杆或梯级或邻近的多个相邻杆或梯级的中心。

8. 发明申请

US20120256630A1 DYNAMIC NUCLEAR POLARIZATION APPARATUS WITH SAMPLE TRANSPORT SYSTEM 审中-公开
标题翻译：动态核极化装置与样品运输系统
公开(公告)号：US20120256630A1
公开(公告)日：2012-10-11
申请号：US13516747
申请日：2010-12-28
申请人： Christoph Leussler , Daniel Wirtz , Peter Boernert , Jochen Keupp , Holger Eggers , Bernd David , Johannes Adrianus Overweg , Rainer Eckart
发明人： Christoph Leussler , Daniel Wirtz , Peter Boernert , Jochen Keupp , Holger Eggers , Bernd David , Johannes Adrianus Overweg , Rainer Eckart
IPC分类号： G01R33/28
CPC分类号： G01R33/62 , G01R33/282 , G01R33/5601 , G01R33/5605 , G01R33/5608 , G01R33/56366 , G01R33/56383
摘要： The invention relates to a dynamic nuclear polarization apparatus (116) for continuous provision of hyperpolarized samples (114) comprising dynamically nuclear polarized nuclear spins, the apparatus (116) comprising a polarization region (106) for polarization of said nuclear spins resulting in said hyperpolarized samples, wherein the apparatus (116) further comprises: a cryostat (102) for cooling the samples (114) in the polarization region (106), a magnet (100) for providing a magnetic field to the cooled samples in the polarization region (106), a radiation source (112) for concurrently to the magnetic field provision providing a nuclear polarizing radiation to the polarization region (106) for receiving the hyperpolarized samples, a sample transport system (104) for continuously receiving unpolarized samples (114), transporting the unpolarized samples to the polarization region (106) for nuclear spin polarization and providing the resulting hyperpolarized samples (114).
摘要翻译：本发明涉及用于连续提供包括动态核偏振核自旋的超极化样本（114）的动态核极化装置（116），所述装置（116）包括用于所述核自旋的极化的偏振区域（106），导致所述超极化样品，其中所述装置（116）还包括：用于冷却所述偏振区域（106）中的样品（114）的低温恒温器（102），用于向所述偏振区域中的所述冷却样品提供磁场的磁体（100） 106），用于与磁场提供同时提供用于接收超极化样本的偏振区域（106）的核偏振辐射的辐射源（112），用于连续接收非偏振样本（114）的样本传输系统（104）将非偏振样品运送到用于核自旋极化的偏振区域（106），并提供所得到的超极化样本（114）。

9. 发明申请

US20100312091A1 MAGNETIC RESONANCE SAFETY MONITORING SYSTEMS AND METHODS 有权
标题翻译：磁共振安全监测系统及方法
公开(公告)号：US20100312091A1
公开(公告)日：2010-12-09
申请号：US12808404
申请日：2008-12-22
申请人： Sascha Krueger , Daniel Wirtz , Steffen Weiss
发明人： Sascha Krueger , Daniel Wirtz , Steffen Weiss
IPC分类号： A61B5/055 , G08B23/00
CPC分类号： G01R33/285 , G01R33/288
摘要： A magnetic resonance method comprises applying a radio frequency excitation in an examination region (14), measuring a magnetic resonance signal generated by the applied radio frequency excitation in a subject (16) in the examination region, monitoring a radio frequency parameter during the applying, and evaluating subject safety based on the monitoring. A magnetic resonance safety monitor (40) comprises an analyzer (42, 44, 46, 50) configured to (i) receive a radio frequency signal during magnetic resonance excitation, (ii) extract a radio frequency parameter from the received radio frequency signal, and (iii) evaluate subject safety based on the extracted radio frequency parameter, and a remediation module (54) configured to perform a remediation of the magnetic resonance excitation responsive to the evaluation (iii) indicating a potentially unsafe condition.
摘要翻译：磁共振方法包括在检查区域（14）中施加射频激励，测量由所述检查区域中的被检体（16）施加的射频激励产生的磁共振信号，在施加期间监视射频参数，并根据监测评估受试者的安全性。磁共振安全监视器（40）包括分析器（42,44,46,50），其被配置为（i）在磁共振激励期间接收射频信号，（ii）从所接收的射频信号中提取射频参数，以及（iii）基于提取的射频参数来评估对象安全性;以及修复模块（54），其被配置为响应于指示潜在不安全状况的评估（iii）来执行磁共振激励的修复。

10. 发明授权

US09968277B2 Magnetic resonance guidance of a shaft to a target zone 有权
公开(公告)号：US09968277B2
公开(公告)日：2018-05-15
申请号：US14007990
申请日：2012-04-04
申请人： Steffen Weiss , Ronaldus Frederik Johannes Holthuizen , Sascha Krueger , Peter Koken , Daniel Wirtz , Thomas Erik Amthor , Falk Uhlemann
发明人： Steffen Weiss , Ronaldus Frederik Johannes Holthuizen , Sascha Krueger , Peter Koken , Daniel Wirtz , Thomas Erik Amthor , Falk Uhlemann
IPC分类号： A61B5/055 , G01R33/28 , A61B5/06 , A61B5/00 , G01R33/34
CPC分类号： A61B5/055 , A61B5/064 , A61B5/6832 , A61B5/72 , G01R33/287 , G01R33/34084
摘要： A medical apparatus (1100) comprising a magnetic resonance imaging system and an interventional device (300) comprising a shaft (302, 1014, 1120). The medical apparatus further comprises a toroidal magnetic resonance fiducial marker (306, 600, 800, 900, 1000, 1122) attached to the shaft. The shaft passes through a center point (610, 810, 908, 1006) of the fiducial marker. The medical apparatus further comprises machine executable instructions (1150, 1152, 1154, 1156, 1158) for execution by a processor. The instructions cause the processor to acquire (100, 200) magnetic resonance data, to reconstruct (102, 202) a magnetic resonance image (1142), and to receive (104, 204) the selection of a target volume (1118, 1144, 1168). The instructions further cause the processor to repeatedly: acquire (106, 206) magnetic resonance location data (1146) from the fiducial marker and render (108, 212) a view (1148, 1162) indicating the position of the shaft relative to the target zone.

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