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1. 发明授权

US09763937B2 Aminoheteroaryl benzamides as kinase inhibitors 有权
公开(公告)号：US09763937B2
公开(公告)日：2017-09-19
申请号：US14964057
申请日：2015-12-09
申请人： Jeffrey T. Bagdanoff , Yu Ding , Wooseok Han , Zilin Huang , Qun Jiang , Xianming Jin , Xiang Kou , Patrick Lee , Mika Lindvall , Zhongcheng Min , Yue Pan , Sabina Pecchi , Keith Bruce Pfister , Daniel Poon , Vivek Rauniyar , Xiaojing Michael Wang , Qiong Zhang , Jianguang Zhou , Shejin Zhu
发明人： Jeffrey T. Bagdanoff , Yu Ding , Wooseok Han , Zilin Huang , Qun Jiang , Xianming Jin , Xiang Kou , Patrick Lee , Mika Lindvall , Zhongcheng Min , Yue Pan , Sabina Pecchi , Keith Bruce Pfister , Daniel Poon , Vivek Rauniyar , Xiaojing Michael Wang , Qiong Zhang , Jianguang Zhou , Shejin Zhu
IPC分类号： C07D241/02 , A61K31/4965 , A61K31/497 , A61K31/4433 , A61K31/44 , A61K31/4436 , A61K31/5355
CPC分类号： A61K31/497 , A61K31/44 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/4545 , A61K31/4965 , A61K31/506 , A61K31/5355 , A61K31/5377 , A61K31/5383 , A61K31/553 , A61K45/06 , A61K2121/00 , C07D213/73 , C07D241/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/06 , C07D405/04 , C07D405/14 , C07D409/04 , C07D413/14 , C07D498/04
摘要： The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.

2. 发明申请

US20170182038A1 AMINOHETEROARYL BENZAMIDES AS KINASE INHIBITORS 审中-公开
公开(公告)号：US20170182038A1
公开(公告)日：2017-06-29
申请号：US14964057
申请日：2015-12-09
申请人： Jeffrey T. BAGDANOFF , Yu DING , Wooseok HAN , Zilin HUANG , Qun JIANG , Xianming JIN , Xiang KOU , Patrick LEE , Mika LINDVALL , Zhongcheng MIN , Yue PAN , Sabina PECCHI , Keith Bruce PFISTER , Daniel POON , Vivek RAUNIYAR , Xiaojing Michael WANG , Qiong ZHANG , Jianguang ZHOU , Shejin ZHU
发明人： Jeffrey T. BAGDANOFF , Yu DING , Wooseok HAN , Zilin HUANG , Qun JIANG , Xianming JIN , Xiang KOU , Patrick LEE , Mika LINDVALL , Zhongcheng MIN , Yue PAN , Sabina PECCHI , Keith Bruce PFISTER , Daniel POON , Vivek RAUNIYAR , Xiaojing Michael WANG , Qiong ZHANG , Jianguang ZHOU , Shejin ZHU
IPC分类号： A61K31/497 , A61K31/5355 , A61K31/4436 , A61K31/4433 , A61K31/44
CPC分类号： A61K31/497 , A61K31/44 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/4545 , A61K31/4965 , A61K31/506 , A61K31/5355 , A61K31/5377 , A61K31/5383 , A61K31/553 , A61K45/06 , A61K2121/00 , C07D213/73 , C07D241/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/06 , C07D405/04 , C07D405/14 , C07D409/04 , C07D413/14 , C07D498/04
摘要： The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.

3. 外观设计

USD770321S1 Wrist band device case 有权
标题翻译：腕带装置盒
公开(公告)号：USD770321S1
公开(公告)日：2016-11-01
申请号：US29511474
申请日：2014-12-11
申请人： Jennifer Ann Murphy , Daniel Poon , Aaron Jones , Timothy Brian Chalfant
设计人： Jennifer Ann Murphy , Daniel Poon , Aaron Jones , Timothy Brian Chalfant

4. 发明授权

US08865732B2 Heterocyclic compounds and uses thereof 有权
标题翻译：杂环化合物及其用途
公开(公告)号：US08865732B2
公开(公告)日：2014-10-21
申请号：US13396339
申请日：2012-02-14
申请人： Zilin Huang , Jeff Jin , Timothy Machajewski , William R. Antonios-McCrea , Maureen McKenna , Daniel Poon , Paul A. Renhowe , Martin Sendzik , Cynthia Shafer , Aaron Smith , Yongjin Xu , Qiong Zhang , Zheng Chen
发明人： Zilin Huang , Jeff Jin , Timothy Machajewski , William R. Antonios-McCrea , Maureen McKenna , Daniel Poon , Paul A. Renhowe , Martin Sendzik , Cynthia Shafer , Aaron Smith , Yongjin Xu , Qiong Zhang , Zheng Chen
IPC分类号： A61K31/505 , C07D241/02
CPC分类号： A61K31/4439 , A61K31/444 , A61K31/4709 , A61K31/497 , A61K31/506 , A61K31/5383 , A61K45/06 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D498/04 , A61K2300/00
摘要： New substituted heterocyclic compounds, compositions containing them, and methods of using them for the inhibition of Raf kinase activity are provided. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
摘要翻译：提供了新的取代的杂环化合物，含有它们的组合物，以及使用它们来抑制Raf激酶活性的方法。新化合物和组合物可以单独使用或与至少一种另外的药物组合使用，用于治疗Raf激酶介导的病症，例如癌症。

5. 外观设计

USD711362S1 Case for a phone 有权
标题翻译：手机案例
公开(公告)号：USD711362S1
公开(公告)日：2014-08-19
申请号：US29444472
申请日：2013-01-31
申请人： Daniel Poon
设计人： Daniel Poon

6. 发明申请

US20140011825A1 Compounds and Compositions as Protein Kinase Inhibitors 有权
标题翻译：化合物和组合物作为蛋白激酶抑制剂
公开(公告)号：US20140011825A1
公开(公告)日：2014-01-09
申请号：US14022540
申请日：2013-09-10
申请人： Abran Q. Costales , Shenlin Huang , Jeff Xianming Jin , Zuosheng Liu , Sabina Pecchi , Daniel Poon , John Tellew
发明人： Abran Q. Costales , Shenlin Huang , Jeff Xianming Jin , Zuosheng Liu , Sabina Pecchi , Daniel Poon , John Tellew
IPC分类号： C07D403/04 , A61K45/06 , A61K31/506
CPC分类号： C07D403/04 , A61K31/506 , A61K45/06
摘要： The present invention provides compounds of Formula I or II: wherein R1, R1b, R2, R3, R4, R5, R6 and R7 are defined herein. The compounds of Formula (I) or (II) and pharmaceutical compositions thereof are useful for the treatment of B-Raf-associated diseases.
摘要翻译：本发明提供式I或II的化合物：其中R1，R1b，R2，R3，R4，R5，R6和R7如本文所定义。式（I）或（II）的化合物及其药物组合物可用于治疗B-Raf相关疾病。

7. 发明授权

US08202876B2 Compounds and compositions as protein kinase inhibitors 有权
标题翻译：化合物和组合物作为蛋白激酶抑制剂
公开(公告)号：US08202876B2
公开(公告)日：2012-06-19
申请号：US12444129
申请日：2007-09-24
申请人： Pamela Albaugh , Gregory B. Chopiuk , Qiang Ding , Shenlin Huang , Zuosheng Liu , Shifeng Pan , Pingda Ren , Xia Wang , Xing Wang , Yongping Xie , Chengzhi Zhang , Qiong Zhang , Guobao Zhang , Daniel Poon , Paul Renhowe , Martin Sendzik
发明人： Pamela Albaugh , Gregory B. Chopiuk , Qiang Ding , Shenlin Huang , Zuosheng Liu , Shifeng Pan , Pingda Ren , Xia Wang , Xing Wang , Yongping Xie , Chengzhi Zhang , Qiong Zhang , Guobao Zhang , Daniel Poon , Paul Renhowe , Martin Sendzik
IPC分类号： C07D401/00 , C07D403/00 , C07D405/00 , C07D409/00 , C07D411/00 , C07D413/00 , C07D417/00 , C07D419/00 , C07D231/00 , C07D403/02 , A01N43/56 , A61K31/415
CPC分类号： C07D403/04 , C07D401/14 , C07D403/14 , C07D405/14 , C07D417/14
摘要： The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, ARG, BCR-Abl, BRK, EphB, Fms, Fyn, KDR, c-Kit, LCK, PDGF-R, b-Raf, c-Raf, SAPK2, Src, Tie2 and TrkB kinases.
摘要翻译：本发明提供了一类新颖的化合物，包含这些化合物的药物组合物和使用这些化合物治疗或预防与异常或失调的激酶活性相关的疾病或病症的方法，特别是涉及Abl，ARG，BCR异常活化的疾病或病症 -Abl，BRK，EphB，Fms，Fyn，KDR，c-Kit，LCK，PDGF-R，b-Raf，c-Raf，SAPK2，Src，Tie2和TrkB激酶。

8. 发明授权

US08129394B2 Heteroaryl-substituted imidazole compounds and uses thereof 失效
标题翻译：杂芳基取代的咪唑化合物及其用途
公开(公告)号：US08129394B2
公开(公告)日：2012-03-06
申请号：US12383035
申请日：2009-03-19
申请人： Zilin Hunag , Jeff Jin , Timothy Machajewski , William R. Antonios-McCrea , Maureen McKenna , Daniel Poon , Paul A. Renhowe , Martin Sendzik , Cynthia Shafer , Aaron Smith , Yongjin Xu , Qiong Zhang , Zheng Chen
发明人： Zilin Hunag , Jeff Jin , Timothy Machajewski , William R. Antonios-McCrea , Maureen McKenna , Daniel Poon , Paul A. Renhowe , Martin Sendzik , Cynthia Shafer , Aaron Smith , Yongjin Xu , Qiong Zhang , Zheng Chen
IPC分类号： A61K31/4965 , A61K31/505 , A01N43/54 , C07D403/00 , C07D401/00 , C07D405/00 , C07D409/00 , C07D411/00 , C07D413/00 , C07D417/00 , C07D419/00
CPC分类号： C07D498/04 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04
摘要： Novel imidazole compounds of the general formula are disclosed, wherein R1 and R2 comprise heteroaryl groups. These compounds and compositions containing them are useful in methods to treat Raf kinase-mediated disorders such as cancer.
摘要翻译：公开了通式的新型咪唑化合物，其中R 1和R 2包含杂芳基。这些含有它们的化合物和组合物可用于治疗Raf激酶介导的疾病如癌症的方法。

9. 发明申请

US20100304623A1 ELECTRO-MECHANICAL CONNECTOR FOR SOLAR ARRAYS 有权
标题翻译：太阳能电力机电连接器
公开(公告)号：US20100304623A1
公开(公告)日：2010-12-02
申请号：US12787602
申请日：2010-05-26
申请人： Daniel Poon , Kyle Smith
发明人： Daniel Poon , Kyle Smith
IPC分类号： H01R13/33
CPC分类号： H01L31/0508 , F16B5/0635 , F16B2001/0064 , F24S25/67 , Y02E10/50
摘要： A connector assembly is provided for connecting, two planar surfaces or structures together to permit electrical transmission between the two. As described, the connector have at least two housing sections having grooves formed therein for receiving springs, such as canted coil springs. The springs are configured to provide constant mechanical and electrical connection between multiple parts and allow for small motions between such parts. By allowing for movement of the connected parts, adequate connection during thermal changes and/or vibrations is maintained. This is possible due to the spring contact interface between the connector assembly and the connecting parts, which allows relative movement between the springs and the connecting parts.
摘要翻译：提供连接器组件用于将两个平面表面或结构连接在一起以允许两者之间的电传输。如上所述，连接器具有至少两个壳体部分，其中形成有用于接收弹簧的槽，例如倾斜螺旋弹簧。弹簧构造成在多个部件之间提供恒定的机械和电气连接，并允许这些部件之间的小运动。通过允许连接部件的移动，保持在热变化和/或振动期间的充分连接。这是可能的，因为连接器组件和连接部件之间的弹簧接触界面，这允许弹簧和连接部件之间的相对移动。

10. 外观设计

USD776098S1 Case for portable electronic communications device 有权
标题翻译：便携式电子通信设备案例
公开(公告)号：USD776098S1
公开(公告)日：2017-01-10
申请号：US29498106
申请日：2014-07-31
申请人： Daniel Poon
设计人： Daniel Poon

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