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1. 发明授权

US10980737B1 System for treating unwanted tissue using heat and heat activated drugs 有权
公开(公告)号：US10980737B1
公开(公告)日：2021-04-20
申请号：US15452712
申请日：2017-03-07
申请人： Samuel Victor Lichtenstein , Daniel Gelbart
发明人： Samuel Victor Lichtenstein , Daniel Gelbart
IPC分类号： A61K9/00 , A61M31/00 , A61M16/14 , A61B18/14 , A61K45/06 , A61B18/00
摘要： The invention can selectively heat a diseased area in the lung while minimizing heating to the healthy area and surrounding tissue. This is done by exposing the lung to an electromagnetic field causing dielectric or eddy current heating. The invention is particularly useful for treating emphysema as the diseased areas have reduced blood flow. The diseased area will heat up rapidly while the healthy tissue will be cooled by the blood flow. This is particularly effective for treating emphysema because of the low mass of the lungs and the high blood flow. To avoid heating of surrounding organs the direction of the electromagnetic energy is switched in a way it always passes through lungs but only intermittently passes through adjacent organs. If heat activated drugs are present in the lungs, they are selectively released in the heated tissue.

2. 发明授权

US09744038B2 Medical device for constricting tissue or a bodily orifice, for example a mitral valve 有权
公开(公告)号：US09744038B2
公开(公告)日：2017-08-29
申请号：US12899407
申请日：2010-10-06
申请人： Jon Dahlgren , Doug Goertzen , Daniel Gelbart
发明人： Jon Dahlgren , Doug Goertzen , Daniel Gelbart
IPC分类号： A61M31/00 , A61F2/24 , A61B17/04 , A61B17/00 , A61B17/22
CPC分类号： A61F2/2445 , A61B17/0401 , A61B17/0469 , A61B17/0485 , A61B2017/00331 , A61B2017/0409 , A61B2017/0437 , A61B2017/0441 , A61B2017/0464 , A61B2017/0496 , A61B2017/22038 , A61F2/2454
摘要： A medical apparatus positionable in a cavity of a bodily organ (e.g., a heart) may constrict a bodily orifice (e.g., a mitral valve). The medical apparatus may include tissue anchors that are implanted in the annulus of the orifice. The tissue anchors may be guided into position by an intravascularly or percutaneously deployed anchor guiding frame. Constriction of the orifice may be accomplished by cinching a flexible cable attached to implanted tissue anchors. The medical device may be used to approximate the septal and lateral (clinically referred to as anterior and posterior) annulus of the mitral valve in order to move the posterior leaflet anteriorly and the anterior leaflet posteriorly and thereby improve leaflet coaptation and eliminate mitral regurgitation.

3. 发明授权

US08979776B2 Lithotripsy system with automatic 3D tracking 有权
公开(公告)号：US08979776B2
公开(公告)日：2015-03-17
申请号：US12289717
申请日：2008-11-03
申请人： Daniel Gelbart , Lindsay Machan
发明人： Daniel Gelbart , Lindsay Machan
IPC分类号： A61H1/00 , A61B17/225 , A61B17/22
CPC分类号： A61B17/225 , A61B17/2251 , A61B17/2256 , A61B2017/22028
摘要： A lithotripsy system capable of 3D tracking monitors the acoustic reflection from the stone in order to focus the shock wave on the stone regardless of shock wave displacement or stone movement. The tracking and focusing is based on a phased array concept, allowing the lithotripsy head to remain stationary and well coupled to the body. An alternate shock wave steering is based on refraction by a variable liquid wedge.

4. 发明授权

US08615856B1 Apparatus and method for forming self-retaining sutures 有权
标题翻译：用于形成自固定缝线的装置和方法
公开(公告)号：US08615856B1
公开(公告)日：2013-12-31
申请号：US12363582
申请日：2009-01-30
申请人： Daniel Gelbart
发明人： Daniel Gelbart
IPC分类号： B21F25/00 , A61B17/04
CPC分类号： B21F25/00 , A61B17/06166 , A61B2017/00526 , A61B2017/06176 , B21F45/008 , D02G3/448 , D02J3/00 , Y10T29/20
摘要： An apparatus and method for forming retainers on a continuous strand such as, for example, of suture material and a suture produced by the same. The apparatus may include a retainer forming member configured to rotate about a first axis. The retainer forming member may include a cutter, the cutting edge of which may directed substantially inward toward, or outward away from, the first axis to define a retainer forming zone when the retainer forming member rotates about the first axis. The apparatus may further include a support member arranged adjacent to the retainer forming member and configured to receive and support the continuous strand in the retainer forming zone. When the retainer forming member rotates about the first axis, the passing strand may be intermittently or continuously cut by the cutting edge of the cutter.
摘要翻译：一种用于在连续股线上形成保持器的装置和方法，例如缝合材料和由其制成的缝合线。该装置可以包括构造成围绕第一轴线旋转的保持器形成构件。保持器形成构件可以包括切割器，其切割边缘可以朝着第一轴线或向外远离第一轴线指向，以在保持器形成构件围绕第一轴线旋转时限定保持器成形区域。该装置还可以包括邻近保持器形成构件设置并构造成在保持器成形区域中接收和支撑连续线材的支撑构件。当保持器形成构件围绕第一轴线旋转时，通过的线可以由切割器的切割边缘间歇地或连续地切割。

5. 发明申请

US20130226148A1 Mixing syringe 有权
标题翻译：混合注射器
公开(公告)号：US20130226148A1
公开(公告)日：2013-08-29
申请号：US13385627
申请日：2012-02-28
申请人： Lindsay S. Machan , Daniel Gelbart
发明人： Lindsay S. Machan , Daniel Gelbart
IPC分类号： A61M5/31
CPC分类号： A61M5/31596 , A61M2005/31516 , A61M2005/31598 , A61M2205/7545
摘要： A movable mixing disc is inserted into a regular syringe. The mixing disc has a small hole covered by a fine screen, allowing only saline solution to get behind the disc. When the plunger of the syringe is pressed, the saline solution emerges from the mixing disc hole as a high velocity jet, stirring up the settled particles. As the ejection continues, the mixing disc is pushed forward by the plunger in order to eliminate any unused volume.
摘要翻译：将可动混合盘插入常规注射器中。混合盘具有被细筛网覆盖的小孔，只允许盐水溶液到达盘后。当注射器的柱塞被按压时，盐溶液作为高速喷射从混合盘孔中排出，搅拌沉降的颗粒。当喷射继续时，混合盘被柱塞向前推动，以消除任何未使用的体积。

6. 发明授权

US08337524B2 Method and device for closing holes in tissue 有权
标题翻译：用于封闭组织中的孔的方法和装置
公开(公告)号：US08337524B2
公开(公告)日：2012-12-25
申请号：US12777883
申请日：2010-05-11
申请人： Daniel Gelbart , Samuel Victor Lichtenstein
发明人： Daniel Gelbart , Samuel Victor Lichtenstein
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B2017/00243 , A61B2017/00292 , A61B2017/00575 , A61B2017/00579 , A61B2017/00584 , A61B2017/00592 , A61B2017/00615 , A61B2017/00623 , A61B2017/00637 , A61B2017/00862 , A61B2017/22061
摘要： A device for closing holes in tissue is delivered via a catheter to the inside of a body lumen such as a heart. An elastic barbed clip is expanded, pulled into the tissue and released, pulling the tissue with it. The operation is fully reversible.
摘要翻译：用于封闭组织中的孔的装置通过导管输送到诸如心脏的体腔内部。弹性带刺的夹子被膨胀，拉入组织并释放，用它拉动组织。操作完全可逆。

7. 发明申请

US20120215095A1 X-Ray radiation reduction system 审中-公开
标题翻译： X射线辐射降低系统
公开(公告)号：US20120215095A1
公开(公告)日：2012-08-23
申请号：US13385402
申请日：2012-02-21
申请人： Amit Mordechai Av-Shalom , Meir Deutsch , Daniel Gelbart
发明人： Amit Mordechai Av-Shalom , Meir Deutsch , Daniel Gelbart
IPC分类号： A61B6/00 , A61B6/08
CPC分类号： A61B6/4441 , A61B6/06 , A61B6/405 , A61B6/469 , A61B6/487 , A61B6/542
摘要： By exposing the ROI at full exposure and full frame rate while exposing the area outside the ROI with low exposure and up to full frame rate an overall reduction in X-Ray radiation is achieved. The resultant image has slightly lower resolution outside the ROI but better resolution (as compared to standard fluoroscopy practices) in the ROI because of reduced scattering. Different exposures are supplied to different parts of the image by using a fast shutter in conjunction with the exposure control.
摘要翻译：通过在全曝光和全帧速率下曝光ROI，同时以低曝光和高达全帧速率曝光ROI外部的区域，实现了X射线辐射的全面减少。所得到的图像在ROI之外具有略低的分辨率，但是由于散射减少，ROI中的分辨率（与标准荧光透视实践相比）更好。通过使用快门与曝光控制相结合，将不同的曝光提供给图像的不同部分。

8. 发明授权

US07983391B2 System for reduction of exposure to X-ray radiation 有权
标题翻译：用于减少暴露于X射线辐射的系统
公开(公告)号：US07983391B2
公开(公告)日：2011-07-19
申请号：US12386895
申请日：2009-04-27
申请人： Lindsay S. Machan , Daniel Gelbart
发明人： Lindsay S. Machan , Daniel Gelbart
IPC分类号： H05G1/64 , G21K1/04
CPC分类号： G21K1/04 , A61B6/06 , A61B6/12 , A61B6/4441 , A61B6/504 , G21K1/043
摘要： To reduce X-ray exposure, an area of interest is selected in the image. The image of the selected area is updated frequently, comparable to rate of updates used today for the whole image. The rest of the image is updated at a significantly lower rate. Since the area of interest normally is a small part of the overall area, the total exposure is reduced significantly. A movable X-ray shield placed near the X-ray source blocks the radiation from areas outside the area of interest. The shield automatically retracts when the complete image is updated. The area of interest can be selected by the user or automatically selected based on activity in the image.
摘要翻译：为了减少X射线曝光，图像中选择感兴趣区域。所选区域的图像经常更新，与整个图像当前使用的更新速率相当。图像的其余部分以显着较低的速率更新。由于感兴趣的区域通常是整个区域的一小部分，因此总体暴露量显着降低。放置在X射线源附近的可移动的X射线屏蔽物阻挡来自感兴趣区域外的区域的辐射。完整的图像更新后，屏幕会自动缩回。感兴趣区域可以由用户选择或根据图像中的活动自动选择。

9. 发明申请

US20110125172A1 AUTOMATIC ATHERECTOMY SYSTEM 有权
标题翻译：自动化系统
公开(公告)号：US20110125172A1
公开(公告)日：2011-05-26
申请号：US12950871
申请日：2010-11-19
申请人： Daniel Gelbart , Samuel Victor Lichtenstein
发明人： Daniel Gelbart , Samuel Victor Lichtenstein
IPC分类号： A61B17/22
CPC分类号： A61B5/053 , A61B5/0538 , A61B17/320758 , A61B2017/00022 , A61B2017/00026 , A61B2017/00084 , A61B2017/003 , A61B2017/00539 , A61B2017/320004
摘要： An automatic atherectomy system uses a rotary burr at the tip of a catheter as a sensing device, in order to measure both electrical conductivity and permittivity of surrounding tissue at multiple frequencies. From these parameters it is determined which tissue lies in different directions around the tip. A servo system steers the catheter tip in the direction of the tissue to be removed. In non-atherectomy applications the rotary burr can be replaced with any desired tool and the system can be used to automatically steer the catheter to the desired position. The steering may be done hydraulically, by pressurizing miniature bellows located near the catheter tip.
摘要翻译：自动斑块切除术系统使用导管末端的旋转毛刺作为感测装置，以便测量多个频率的周围组织的电导率和介电常数。根据这些参数，确定哪个组织位于尖端周围的不同方向。伺服系统沿着要移除的组织的方向引导导管尖端。在非粥样斑块切除术应用中，旋转毛刺可以用任何所需的工具代替，并且该系统可用于将导管自动转向所需位置。通过对位于导管末端附近的微型波纹管进行加压，可以液压地进行转向。

10. 发明申请

US20110082538A1 MEDICAL DEVICE, KIT AND METHOD FOR CONSTRICTING TISSUE OR A BODILY ORIFICE, FOR EXAMPLE, A MITRAL VALVE 审中-公开
标题翻译：用于约束组织或身体组织的医疗装置，工具包和方法，例如，麻药阀
公开(公告)号：US20110082538A1
公开(公告)日：2011-04-07
申请号：US12894912
申请日：2010-09-30
申请人： Jonathan Dahlgren , Douglas Goertzen , Daniel Gelbart , Kelly Watkinson , Derrick To
发明人： Jonathan Dahlgren , Douglas Goertzen , Daniel Gelbart , Kelly Watkinson , Derrick To
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61B17/00234 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B2017/00243 , A61B2017/003 , A61B2017/00411 , A61B2017/00783 , A61B2017/00867 , A61B2017/0409 , A61B2017/0437 , A61B2017/0441 , A61B2017/045 , A61B2017/0464 , A61B2017/0496 , A61B2017/22038 , A61F2/2466 , A61F2210/0014 , A61F2220/0016 , A61F2230/0091
摘要： A device, kit and method may include or employ an implantable device (e.g., annuloplasty implant) and a tool operable to implant such. The implantable device is positionable in a cavity of a bodily organ (e.g., a heart) and operable to constrict a bodily orifice (e.g., a mitral valve). The tissue anchors may be guided into precise position by an intravascularly or percutaneously deployed anchor guide frame of the tool and embedded in an annulus of the orifice. Constriction of the orifice may be accomplished via a variety of structures, for example by cinching a flexible cable or via a anchored annuloplasty ring, the cable or ring attached to the tissue anchors. The annuloplasty ring may be delivered in an unanchored, generally elongated configuration, and implanted in an anchored generally arch, arcuate or annular configuration. Such may approximate the septal and lateral (clinically referred to as anterior and posterior) annulus of the mitral valve, to move the posterior leaflet anteriorly and the anterior leaflet posteriorly, thereby improving leaflet coaptation to eliminate mitral regurgitation.
摘要翻译：装置，套件和方法可以包括或采用可植入装置（例如，瓣膜成形植入物）和可操作以植入其的工具。可植入装置可定位在身体器官（例如，心脏）的空腔中并且可操作以收缩身体孔口（例如二尖瓣）。组织锚固件可以通过工具的血管内或经皮部署的锚定引导框架被引导到精确位置，并且嵌入孔的环形空间中。孔的收缩可以通过各种结构来实现，例如通过将柔性电缆束紧或经由锚定的瓣膜成形术环，连接到组织锚的电缆或环来实现。瓣环成形术环可以以非锚定的，大体上细长的构造递送，并且以锚定的大致拱形，弓形或环形构型植入。这可能近似于二尖瓣的间隔和外侧（临床称为前后）环，以向后移动后叶和前叶，从而改善小叶接合以消除二尖瓣反流。

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