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1. 发明申请

WO2010105995A3 ZOO-TECHNICAL DRUG DELIVERY DEVICE 审中-公开
标题翻译： ZOO技术药物递送设备
公开(公告)号：WO2010105995A3
公开(公告)日：2011-01-20
申请号：PCT/EP2010053240
申请日：2010-03-15
申请人： INTERVET INT BV , ORGANON NV , DRIANCOURT MARC-ANTOINE , DE GRAAFF WOUTER , ZEEMAN RAYMOND
发明人： DRIANCOURT MARC-ANTOINE , DE GRAAFF WOUTER , ZEEMAN RAYMOND
IPC分类号： A61K9/00 , A23K1/18 , A61K31/56
CPC分类号： A61K9/5073 , A61K9/0024 , A61K9/0036 , A61K31/565 , A61K31/567 , A61K31/57 , A61K45/06 , A61K47/32 , A61K2300/00
摘要： The present invention relates to a veterinary zoo-technical drug delivery system (device) for the simultaneous release of two or more active substances, which system releases the active substances in a substantially constant ratio over a prolonged period of time. The drug delivery system can be in different forms, such as e.g. an implant, or a intravaginal device such as a helical coil, a spring or a ring.
摘要翻译：本发明涉及用于同时释放两种或多种活性物质的兽医动物园技术药物递送系统（装置），该系统在长时间内以基本恒定的比例释放活性物质。药物递送系统可以是不同的形式，例如，植入物或阴道内装置，例如螺旋线圈，弹簧或环。

2. 发明申请

WO2008061963A3 HELICALLY-SHAPED DRUG DELIVERY SYSTEM 审中-公开
标题翻译：螺旋形药物递送系统
公开(公告)号：WO2008061963A3
公开(公告)日：2008-11-06
申请号：PCT/EP2007062514
申请日：2007-11-19
申请人： ORGANON NV , INTERVET INT BV , DRIANCOURT MARC-ANTOINE , DE GRAAFF WOUTER , BUTTAFOCO LAURA , PAYOT FABRICE , VEENSTRA HARM , VOSS RENE
发明人： DRIANCOURT MARC-ANTOINE , DE GRAAFF WOUTER , BUTTAFOCO LAURA , PAYOT FABRICE , VEENSTRA HARM , VOSS RENE
IPC分类号： A61K9/00
CPC分类号： A61K9/0036 , A61K31/575 , A61K47/32
摘要： The present invention relates to a helically-shaped medicated veterinary system suitable for delivery of a drug to the vaginal cavity of a female non-human mammal and to a method of manufacture. The drug delivery system is helically-shaped and comprises a three layered polymer fibre. The polymer fibre comprises a polymer core, a polymer intermediate layer comprising a drug, and a polymer skin. The medicated system provides a controlled delivery of drug to the vaginal cavity of the mammal. The present invention also relates to a process of making the springs.
摘要翻译：本发明涉及适用于将药物递送至雌性非人类哺乳动物的阴道腔的螺旋形药物兽医系统及其制造方法。药物递送系统是螺旋形的并且包含三层聚合物纤维。聚合物纤维包含聚合物芯，包含药物的聚合物中间层和聚合物表层。加药系统提供药物到哺乳动物阴道腔的受控递送。本发明还涉及一种制造弹簧的方法。

3. 发明申请

WO2011086175A1 TOOL FOR MANIPULATING AN OBJECT IN A BODY CAVITY 审中-公开
标题翻译：用于操纵身体中的物体的工具
公开(公告)号：WO2011086175A1
公开(公告)日：2011-07-21
申请号：PCT/EP2011/050499
申请日：2011-01-17
申请人： INTERVET INTERNATIONAL B.V. , MIDDELBEEK, Hans Almer , SMIT, Jozefus A. C. , DRIANCOURT, Marc-Antoine , PROHACZIK, Angella
发明人： MIDDELBEEK, Hans Almer , SMIT, Jozefus A. C. , DRIANCOURT, Marc-Antoine , PROHACZIK, Angella
IPC分类号： A61M31/00 , A61D7/00 , A61F6/18
CPC分类号： A61M31/00 , A61D7/00 , A61F6/18
摘要： A tool for manipulating a solid object (12) in a cavity (16) of a human or animal body, comprising a longitudinal rod member (14) adapted for insertion into said body cavity (16), a first coupling member (26) connected to one of the rod member (14) and the object (12) through a flexible filament (28), and a second coupling member (24) connected to the other of the rod member and the object, said first and second coupling members being arranged for being mechanically coupled together through magnetic attraction, wherein one of the first and second coupling members forms a recess (30), the other of the first and second coupling members is configured as a key member (26), and magnetic poles of at least one of the first and second coupling members are arranged for drawing the key member into the recess along a direction perpendicular to the longitudinal direction of the rod member, wherein the key member and recess are constituted such that when the key member is drawn into the recess, an operative contact surface exists between the key member and the recess, the said contact surface extending in a direction perpendicular to the longitudinal direction of the rod member.
摘要翻译：一种用于操纵人体或动物体的空腔（16）中的固体物体（12）的工具，包括适于插入所述体腔（16）中的纵向杆构件（14），连接到所述第一联接构件（26）通过柔性灯丝（28）与杆构件（14）和物体（12）中的一个连接，以及连接到杆构件和物体中的另一个的第二联接构件（24），所述第一和第二联接构件是布置成通过磁吸引力机械耦合在一起，其中第一和第二联接构件中的一个形成凹部（30），第一和第二联接构件中的另一个构造为键构件（26），并且磁极所述第一和第二联接构件中的至少一个被布置成沿着与所述杆构件的纵向方向垂直的方向将所述键构件拉入所述凹部中，其中所述键构件和所述凹部被构造成使得当所述键构件被拉入休息时间操作接触表面存在于键构件和凹部之间，所述接触表面沿与杆构件的纵向方向垂直的方向延伸。

4. 发明申请

WO2008061963A2 HELICALLY-SHAPED DRUG DELIVERY SYSTEM 审中-公开
标题翻译：简单形式的药物递送系统
公开(公告)号：WO2008061963A2
公开(公告)日：2008-05-29
申请号：PCT/EP2007/062514
申请日：2007-11-19
申请人： N.V. ORGANON , INTERVET INTERNATIONAL B.V. , DRIANCOURT, Marc-Antoine , DE GRAAFF, Wouter , BUTTAFOCO, Laura , PAYOT, Fabrice , VEENSTRA, Harm , VOSS, René
发明人： DRIANCOURT, Marc-Antoine , DE GRAAFF, Wouter , BUTTAFOCO, Laura , PAYOT, Fabrice , VEENSTRA, Harm , VOSS, René
IPC分类号： A61K9/00
CPC分类号： A61K9/0036 , A61K31/575 , A61K47/32
摘要： The present invention relates to a helically-shaped medicated veterinary system suitable for delivery of a drug to the vaginal cavity of a female non-human mammal and to a method of manufacture. The drug delivery system is helically-shaped and comprises a three layered polymer fibre. The polymer fibre comprises a polymer core, a polymer intermediate layer comprising a drug, and a polymer skin. The medicated system provides a controlled delivery of drug to the vaginal cavity of the mammal. The present invention also relates to a process of making the springs.
摘要翻译：本发明涉及一种适合于将药物递送至女性非人哺乳动物的阴道腔的螺旋形药物兽医系统及其制造方法。药物递送系统是螺旋形的并且包括三层聚合物纤维。聚合物纤维包括聚合物芯，包含药物的聚合物中间层和聚合物皮肤。药物系统提供药物到哺乳动物的阴道腔的受控递送。本发明还涉及制造弹簧的方法。

5. 发明申请

WO2013014269A1 A METHOD TO PROMOTE GROWTH OF A NEWBORN ANIMAL 审中-公开
标题翻译：一种促进新生动物生长的方法
公开(公告)号：WO2013014269A1
公开(公告)日：2013-01-31
申请号：PCT/EP2012/064773
申请日：2012-07-27
申请人： INTERVET INTERNATIONAL B.V. , LEHMANN, Holger , DRIANCOURT, Marc-Antoine
发明人： LEHMANN, Holger , DRIANCOURT, Marc-Antoine
IPC分类号： C07K16/26 , A01K67/027
CPC分类号： C07K16/26 , A61K2039/505 , A61K2039/55
摘要： The present invention pertains to a method to promote growth of a newborn animal, the method comprising administering anti-PYY antibodies to the newborn animal. The invention also pertains to the use of PYY to raise anti-PYY antibodies for the manufacture of a composition comprising these antibodies that after administration to a newborn animal promote growth of this animal and to the use of PYY to manufacture a composition comprising immunogenic PYY for administration to a female animal to induce anti-PYY antibodies in the said animal for passing these antibodies to a newborn animal by allowing the newborn animal to drink milk from the female animal.
摘要翻译：本发明涉及促进新生儿生长的方法，该方法包括向新生动物施用抗PYY抗体。本发明还涉及PYY用于产生抗PYY抗体以制备包含这些抗体的组合物，所述组合物在施用于新生儿动物后促进该动物的生长，并且使用PYY制备包含免疫原性PYY的组合物施用于雌性动物以在所述动物中诱导抗PYY抗体，以通过允许新生动物从雌性动物中饮用牛奶将这些抗体通过新生动物。

6. 发明申请

WO2010105995A2 ZOO-TECHNICAL DRUG DELIVERY DEVICE 审中-公开
标题翻译： ZOO技术药物递送装置
公开(公告)号：WO2010105995A2
公开(公告)日：2010-09-23
申请号：PCT/EP2010/053240
申请日：2010-03-15
申请人： INTERVET INTERNATIONAL B.V. , N.V. ORGANON , DRIANCOURT, Marc-Antoine , DE GRAAFF, Wouter , ZEEMAN, Raymond
发明人： DRIANCOURT, Marc-Antoine , DE GRAAFF, Wouter , ZEEMAN, Raymond
IPC分类号： A61K9/00
CPC分类号： A61K9/5073 , A61K9/0024 , A61K9/0036 , A61K31/565 , A61K31/567 , A61K31/57 , A61K45/06 , A61K47/32 , A61K2300/00
摘要： The present invention relates to a veterinary zoo-technical drug delivery system (device) for the simultaneous release of two or more active substances, which system releases the active substances in a substantially constant ratio over a prolonged period of time. The drug delivery system can be in different forms, such as e.g. an implant, or a intravaginal device such as a helical coil, a spring or a ring.
摘要翻译：本发明涉及用于同时释放两种或多种活性物质的兽用动物园技术药物递送系统（装置），该系统在长时间内以基本恒定的比例释放活性物质。药物递送系统可以是不同的形式，例如，植入物或阴道内装置，例如螺旋线圈，弹簧或环。

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