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1. 发明申请

WO2002072074A1 METHOD TO PREPARE MICROPARTICLES METOPROLOL THAT CONTAIN 审中-公开
标题翻译：制备含有微量元素的方法
公开(公告)号：WO2002072074A1
公开(公告)日：2002-09-19
申请号：PCT/SE2002/000401
申请日：2002-03-06
申请人： ASTRAZENECA AB , DJURLE, Alf , HANSSON, Mikael , SÖDERBOM, Malin
发明人： DJURLE, Alf , HANSSON, Mikael , SÖDERBOM, Malin
IPC分类号： A61K9/16
CPC分类号： A61K9/1688 , A61K9/2081 , A61K9/5047
摘要： A method for the preparation of homogenous microparticles containing metoprolol by a fluidized bed process. The microparticles have a size distribution of less than 250 µm and contain at least 80% by weight of metoprolol.
摘要翻译：一种通过流化床方法制备含有美托洛尔的均匀微粒的方法。微粒的尺寸分布小于250μm，含有至少80重量％的美托洛尔。

2. 发明申请

WO2007084060A1 NEW METHOD AND SYSTEM 审中-公开
标题翻译：新方法和系统
公开(公告)号：WO2007084060A1
公开(公告)日：2007-07-26
申请号：PCT/SE2007/000051
申请日：2007-01-22
申请人： ASTRAZENECA AB , DJURLE, Alf , WURST, Reiner
发明人： DJURLE, Alf , WURST, Reiner
IPC分类号： A61J3/07 , B65B1/32 , B65B1/36
CPC分类号： G01G17/00 , A61J3/074 , B65B1/32 , B65B1/36 , B65B1/46 , Y10S53/90
摘要： The present invention relates to a method for dosing a pharmaceutical product in a packaging machine comprising at least one volumetric dosing unit with a dosing chamber. The method comprises metering a volume of a first component, weighing the first component, introducing the first component into a package and metering a volume of a second component, introduce g the second component into the package and weighing of the package into which the components have being introduced. The invention further relates to a system for dosing a pharmaceutical product in a packaging machine comprising at least one volumetric dosing unit with a dosing chamber. The system comprises at least one volumetric dosing unit for metering a volume of the components. Further, means for introducing the said components into a package and means for weighing the components and the package are comprised. The means for weighing comprises a first weighing unit for weighing the package and the components, and a second weighing unit for weighing the first component after metering the first component by volume and before introducing the first component into the package. (Figure 1)
摘要翻译：本发明涉及一种在包装机中给药产品的计量方法，该方法包括至少一个具有剂量室的体积计量单元。该方法包括计量第一组分的体积，称量第一组分，将第一组分引入包装并计量第二组分的体积，将第二组分引入包装并称重组分所含的包装被介绍本发明还涉及一种用于在包装机中给药产品进行计量的系统，该系统包括至少一个具有剂量室的体积计量单元。该系统包括用于计量一定体积的组分的至少一个体积计量单元。此外，包括将所述部件引入包装的装置和用于称量部件和包装的装置。用于称重的装置包括用于对包装和部件进行称重的第一称重单元和用于在计量第一部件的体积之后并且将第一部件引入包装之前称量第一部件的第二称重单元。（图1）

3. 发明专利

IL192759D0 NEW METHOD AND SYSTEM 未知
公开(公告)号：IL192759D0
公开(公告)日：2009-02-11
申请号：IL19275908
申请日：2008-07-10
申请人： ASTRAZENECA AB , DJURLE ALF , WURST REINER
IPC分类号： A61J20100101
摘要： The present invention relates to a method and system for dosing a pharmaceutical product in a packaging machine having at least one volumetric dosing unit with a dosing chamber. The system check-weighs the volumetrically dosed product with appropriate speed and is integrated into a filling or packaging machine. In accordance with the invention, a volume of a first pharmaceutical component is metered and weighed before being introduced into a package. The procedure is repeated with a second pharmaceutical component. The package containing the components is then weighed. Advantageously, accuracy and precision of the amount of the weighed components can be monitored with the present invention to secure the quality of the pharmaceutical product.

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