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1. 发明申请

WO2009015372A1 PHOTO-PROTECTIVE DERMATOLOGICAL FORMULATIONS AND METHODS OF USING THE SAME 审中-公开
标题翻译：保护性皮肤制剂及其使用方法
公开(公告)号：WO2009015372A1
公开(公告)日：2009-01-29
申请号：PCT/US2008/071263
申请日：2008-07-25
申请人： DERMAPLUS, INC. , DICKMAN, Martin, B. , ENSLEY, Burt, D.
发明人： DICKMAN, Martin, B. , ENSLEY, Burt, D.
IPC分类号： A61K31/401 , A61K38/04 , A61K38/39 , A61K8/44 , A61K8/64 , A61Q17/04
CPC分类号： A61K31/401 , A61K8/44 , A61K8/445 , A61K8/447 , A61K8/4913 , A61K8/492 , A61K8/4946 , A61K38/39 , A61K2800/522 , A61Q17/04 , A61Q19/004 , A61K2300/00
摘要： It is described a dermatological formulation comprising: one or more amino acid-based antioxidants in an amount effective to reduce or repair photodamage to skin exposed to UV radiation; and a dermatologically acceptable carrier, and methods of using the same.
摘要翻译：描述了一种皮肤病学制剂，其包含：一种或多种基于氨基酸的抗氧化剂，其量有效地减少或修复暴露于UV辐射的皮肤的光损伤; 皮肤病学上可接受的载体及其使用方法。

2. 发明申请

WO2006130190A3 PROLINE SUPPRESSES APOPTOSIS 审中-公开
标题翻译：抑制抑制作用
公开(公告)号：WO2006130190A3
公开(公告)日：2007-01-25
申请号：PCT/US2006004349
申请日：2006-02-07
申请人： DICKMAN MARTIN B
发明人： DICKMAN MARTIN B
IPC分类号： C07H21/04
CPC分类号： A61K45/06 , A61K31/401 , A61K2300/00
摘要： The discovery that proline is a potent antioxidant and inhibitor of programmed cell death is described, as are proline-containing compositions and methods for using such compositions in response to, or in advance of, experiencing oxidative stress. These compositions and methods find application across the animal and plant kingdoms. Transgenic plants exhibiting altered intracellular proline levels, as compared to plants lacking such an alteration, are also described, as are transgenic plants that exhibit altered expression of one or more genes involved in the metabolism of reactive oxygen species (ROS), as compared to unmodified plants.
摘要翻译：描述了脯氨酸是有效的抗氧化剂和程序性细胞死亡抑制剂的发现，脯氨酸组合物和使用这些组合物以响应或预先经历氧化应激的方法也被描述。这些组合物和方法可以在整个动物和植物界获得应用。还描述了与缺乏这种改变的植物相比表现出改变的细胞内脯氨酸水平的转基因植物，与未修饰的相比，表现出参与活性氧代谢（ROS）的一种或多种基因表达改变的转基因植物植物。

3. 发明申请

WO2006130190A2 PROLINE SUPPRESSES APOPTOSIS 审中-公开
标题翻译：抑制抑制作用
公开(公告)号：WO2006130190A2
公开(公告)日：2006-12-07
申请号：PCT/US2006/004349
申请日：2006-02-07
申请人： DICKMAN, Martin, B.
发明人： DICKMAN, Martin, B.
CPC分类号： A61K45/06 , A61K31/401 , A61K2300/00
摘要： The discovery that proline is a potent antioxidant and inhibitor of programmed cell death is described, as are proline-containing compositions and methods for using such compositions in response to, or in advance of, experiencing oxidative stress. These compositions and methods find application across the animal and plant kingdoms. Transgenic plants exhibiting altered intracellular proline levels, as compared to plants lacking such an alteration, are also described, as are transgenic plants that exhibit altered expression of one or more genes involved in the metabolism of reactive oxygen species (ROS), as compared to unmodified plants.
摘要翻译：描述了脯氨酸是有效的抗氧化剂和程序性细胞死亡抑制剂的发现，脯氨酸组合物和使用这些组合物以响应或预先经历氧化应激的方法也被描述。这些组合物和方法可以在整个动物和植物界获得应用。还描述了与缺乏这种改变的植物相比表现出改变的细胞内脯氨酸水平的转基因植物，与未修饰的相比，表现出参与活性氧代谢（ROS）的一种或多种基因表达改变的转基因植物植物。

4. 发明申请

WO2010009348A8 TRANSFORMATION OF GLYCEROL AND CELLULOSIC MATERIALS INTO HIGH ENERGY FUELS 审中-公开
标题翻译：甘油和纤维素材料在高能燃料中的转化
公开(公告)号：WO2010009348A8
公开(公告)日：2010-08-26
申请号：PCT/US2009050905
申请日：2009-07-16
申请人： TEXAS A & M UNIV SYS , DE FIGUEIREDO PAUL , LI LEI , NIKOLOV ZIVKO , SHAW BRIAN D , DICKMAN MARTIN B , LOUZADA ELIEZER S , STURINO JOSEPH M , CHANG YING-YING
发明人： DE FIGUEIREDO PAUL , LI LEI , NIKOLOV ZIVKO , SHAW BRIAN D , DICKMAN MARTIN B , LOUZADA ELIEZER S , STURINO JOSEPH M , CHANG YING-YING
IPC分类号： C12P7/00 , C12N1/21 , C12N15/54 , C12R1/865
CPC分类号： C12N1/22 , C12N1/32 , C12N9/1205 , C12P5/00 , C12P5/02 , C12P7/6409 , C12P7/6463 , C12P7/649 , Y02E50/13 , Y02P20/52
摘要： The present invention includes a system and method for making a biofuel comprising: providing a nitrogen-limiting, minimal growth media comprising glycerol, sugars generated from cellulosic biomass or both, under conditions in which an oleaginous microbe converts the growth media into at least one of triacylglycerol, neutral lipids, fatty acids, long-chain fatty acids, and hydrocarbons that is secreted by the microbe.
摘要翻译：本发明包括用于制备生物燃料的系统和方法，包括：在含油微生物将生长培养基转化成以下至少一种的条件下，提供包含甘油，由纤维素生物质产生的糖或两者的限氮最小生长培养基：三酰甘油，中性脂质，脂肪酸，长链脂肪酸和由微生物分泌的烃。

5. 发明申请

WO2008076844A3 NOVEL GENES AND RNA MOLECULES THAT CONFER STRESS TOLERANCE 审中-公开
标题翻译：新的基因和RNA分子，承担压力容忍
公开(公告)号：WO2008076844A3
公开(公告)日：2009-03-12
申请号：PCT/US2007087480
申请日：2007-12-13
申请人： UNL TECHNOLOGY DEV CORP , DICKMAN MARTIN B
发明人： DICKMAN MARTIN B
IPC分类号： A01H5/00 , C12N1/19 , C12N15/11 , C12N15/115
CPC分类号： C12N15/8263 , C12N15/111 , C12N15/115 , C12N15/8271 , C12N15/8279
摘要： Non-coding RNA molecules that include the sequence 5'-AUUU-3', the expression of which confers resistance or tolerance to abiotic and biotic stresses, are described, as are genes encoding the same, expression cassettes and vectors harboring such genes, and transgenic eukaryotic organisms that express such RNAs.
摘要翻译：描述了包括序列5'-AUUU-3'的非编码RNA分子，其表达赋予对非生物和生物胁迫的抗性或耐受性，编码相同的基因，表达盒和携带这种基因的载体，以及表达这种RNA的转基因真核生物。

6. 发明申请

WO2008076844A2 NOVEL GENES AND RNA MOLECULES THAT CONFER STRESS TOLERANCE 审中-公开
标题翻译：新的基因和RNA分子，承担压力容忍
公开(公告)号：WO2008076844A2
公开(公告)日：2008-06-26
申请号：PCT/US2007/087480
申请日：2007-12-13
申请人： UNL TECHNOLOGY DEVELOPMENT CORPORATION , DICKMAN, Martin, B.
发明人： DICKMAN, Martin, B.
IPC分类号： C12N15/11 , C12N15/63 , C12N5/10 , C12N1/21 , C12N1/19 , A01H5/00 , A01G1/00
CPC分类号： C12N15/8263 , C12N15/111 , C12N15/115 , C12N15/8271 , C12N15/8279
摘要： Non-coding RNA molecules that include the sequence 5'-AUUU-3', the expression of which confers resistance or tolerance to abiotic and biotic stresses, are described, as are genes encoding the same, expression cassettes and vectors harboring such genes, and transgenic eukaryotic organisms that express such RNAs.
摘要翻译：描述了包括序列5'-AUUU-3'的非编码RNA分子，其表达赋予对非生物和生物胁迫的抗性或耐受性，编码相同的基因，表达盒和携带这种基因的载体，以及表达这种RNA的转基因真核生物。

7. 发明申请

WO2010009348A3 TRANSFORMATION OF GLYCEROL AND CELLULOSIC MATERIALS INTO HIGH ENERGY FUELS 审中-公开
公开(公告)号：WO2010009348A3
公开(公告)日：2010-05-14
申请号：PCT/US2009050905
申请日：2009-07-16
申请人： TEXAS A & M UNIV SYS , DE FIGUEIREDO PAUL , LI LEI , NIKOLOV ZIVKO , SHAW BRIAN D , DICKMAN MARTIN B , LOUZADA ELIEZER S , STURINO JOSEPH M , CHANG YING-YING
发明人： DE FIGUEIREDO PAUL , LI LEI , NIKOLOV ZIVKO , SHAW BRIAN D , DICKMAN MARTIN B , LOUZADA ELIEZER S , STURINO JOSEPH M , CHANG YING-YING
IPC分类号： C12P7/00 , C12N1/21 , C12N15/54 , C12R1/865
CPC分类号： C12N1/22 , C12N1/32 , C12N9/1205 , C12P5/00 , C12P5/02 , C12P7/6409 , C12P7/6463 , C12P7/649 , Y02E50/13 , Y02P20/52
摘要： The present invention includes a system and method for making a biofuel comprising: providing a nitrogen-limiting, minimal growth media comprising glycerol, sugars generated from cellulosic biomass or both, under conditions in which an oleaginous microbe converts the growth media into at least one of triacylglycerol, neutral lipids, fatty acids, long-chain fatty acids, and hydrocarbons that is secreted by the microbe.

8. 发明申请

WO2010009348A2 TRANSFORMATION OF GLYCEROL AND CELLULOSIC MATERIALS INTO HIGH ENERGY FUELS 审中-公开
标题翻译：甘油和纤维素材料转化为高能燃料
公开(公告)号：WO2010009348A2
公开(公告)日：2010-01-21
申请号：PCT/US2009/050905
申请日：2009-07-16
申请人： THE TEXAS A&M UNIVERSITY SYSTEM , DE FIGUEIREDO, Paul , LI, Lei , NIKOLOV, Zivko , SHAW, Brian, D. , DICKMAN, Martin, B. , LOUZADA, Eliezer, S. , STURINO, Joseph, M. , CHANG, Ying-Ying
发明人： DE FIGUEIREDO, Paul , LI, Lei , NIKOLOV, Zivko , SHAW, Brian, D. , DICKMAN, Martin, B. , LOUZADA, Eliezer, S. , STURINO, Joseph, M. , CHANG, Ying-Ying
IPC分类号： C12P7/00 , C12N1/21 , C12N15/54 , C12R1/865
CPC分类号： C12N1/22 , C12N1/32 , C12N9/1205 , C12P5/00 , C12P5/02 , C12P7/6409 , C12P7/6463 , C12P7/649 , Y02E50/13 , Y02P20/52
摘要： The present invention includes a system and method for making a biofuel comprising: providing a nitrogen-limiting, minimal growth media comprising glycerol, sugars generated from cellulosic biomass or both, under conditions in which an oleaginous microbe converts the growth media into at least one of triacylglycerol, neutral lipids, fatty acids, long-chain fatty acids, and hydrocarbons that is secreted by the microbe.
摘要翻译：本发明包括一种用于生产生物燃料的系统和方法，包括：在油性微生物将生长培养基转化成以下至少一种的条件下，提供包含甘油的氮限制性最小生长培养基，由纤维素生物质或二者生成的糖三酰基甘油，中性脂质，脂肪酸，长链脂肪酸和由微生物分泌的碳氢化合物。

9. 发明申请

WO0222822A3 PLANT DERIVED BAG HOMOLOGUES 审中-公开
标题翻译：植物衍生的袋子同位素
公开(公告)号：WO0222822A3
公开(公告)日：2003-08-07
申请号：PCT/US0129169
申请日：2001-09-14
申请人： UNIV NEBRASKA , DICKMAN MARTIN B
发明人： DICKMAN MARTIN B
IPC分类号： C07K14/415 , C12N15/29 , C12N15/82 , C07K16/16 , G01N33/68
CPC分类号： C07K14/415 , C12N15/8249 , C12N15/8263 , C12N15/8271 , C12N15/8279
摘要： This invention provides isolated BAG polypeptides and functional fragments thereof, isolated nucleic acid molecules encoding the same, methods utilizing the polypeptides or functional fragments thereof, and transgenic plants or transgenic plant cells with altered expression level of BAG genes.
摘要翻译：本发明提供分离的BAG多肽及其功能片段，编码其的分离的核酸分子，利用其多肽或其功能片段的方法以及具有改变的BAG基因表达水平的转基因植物或转基因植物细胞。

10. 发明申请

WO0026391A3 TRANS-SPECIES TRANSFER OF APOPTOTIC GENES AND TRANSGENIC PLANTS DEVELOPED THEREBY 审中-公开
标题翻译：跨物种转基因和与之相关的转基因植物
公开(公告)号：WO0026391A3
公开(公告)日：2000-10-26
申请号：PCT/US9925522
申请日：1999-10-29
申请人： UNIV NEBRASKA LINCOLN , DICKMAN MARTIN B
发明人： DICKMAN MARTIN B
IPC分类号： A01H5/00 , C07K14/47 , C12N5/10 , C12N15/09 , C12N15/82 , C12Q1/68 , C12R1/91 , G01N33/68
CPC分类号： C12N15/8283 , C07K14/4747 , C12N15/8257 , C12N15/8271 , C12N15/8282
摘要： The invention relates to trans-species transfer of apoptotic genes to plant cells, transgenic plants developed therefrom, and screening assays using these plants. The invention also relates to drug discovery screening methods utilizing transgenic plant cells. In addition, the invention relates to methods of identifying plant apoptotic pathway components utilizing non-plant proteins and nucleic acids.
摘要翻译：本发明涉及凋亡基因向植物细胞的跨物种转移，由其开发的转基因植物以及使用这些植物的筛选测定。本发明还涉及利用转基因植物细胞的药物发现筛选方法。另外，本发明涉及利用非植物蛋白和核酸鉴定植物细胞凋亡途径组分的方法。

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