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1. 发明申请

US20100323996A1 MEANS AND METHODS OF CONTROLLING COMMENSALES 审中-公开
标题翻译：手段和控制方法
公开(公告)号：US20100323996A1
公开(公告)日：2010-12-23
申请号：US12867766
申请日：2009-02-18
申请人： Dechert Ute , Eck Jurgen , Krohn Michael
发明人： Dechert Ute , Eck Jurgen , Krohn Michael
IPC分类号： A61K31/122 , C07C49/647 , A61K31/60 , A61K31/17 , A61Q19/00 , A01P1/00 , A01N35/06
CPC分类号： A61K8/35 , A61L27/54 , A61L29/16 , A61L31/16 , A61L2300/404 , A61Q17/005
摘要： The present invention relates to a cosmetic composition for the cleaning of the skin, said composition comprising or consisting of one or more compounds of formula (I) wherein represents a single bond or double bond; R1 and R2 are independently selected from H, linear or branched C1 to C4 alkyl, linear or branched C1 to C4 alkenyl, linear or branched C1 to C4 alkinyl, and linear or branched C1 to C4 alkanoyl; R4 is selected from H, linear or branched C1 to C4 alkyl, linear or branched C1 to C4 alkenyl, and linear or branched C1 to C4 alkinyl; and R3 and R5 are independently selected from H, OH and halogen, or R3 and R5 together are O to form an epoxid, wherein represents a single bond in case R3 and R5 together are O. Also provided are means and methods for the prevention or reduction of biofilm formation on an intracorporeal device and/or for the removal of biofilm from an intracorporeal device, wherein said biofilm comprises or consists of bacteria of the genus Propionibacterium. Furthermore provided is an intracorporeal device which is coated and/or loaded with one or more compounds as defined above.
摘要翻译：本发明涉及一种用于清洁皮肤的化妆品组合物，所述组合物包含一种或多种式（I）化合物或其组合，其中代表单键或双键; R 1和R 2独立地选自H，直链或支链C 1至C 4烷基，直链或支链C 1至C 4烯基，直链或支链C 1至C 4炔基，和直链或支链C 1至C 4烷酰基; R4选自H，直链或支链C1至C4烷基，直链或支链C1至C4烯基，直链或支链C1至C4炔基; 并且R 3和R 5独立地选自H，OH和卤素，或者R 3和R 5一起为O以形成环氧化物，其中在R 3和R 5一起为O的情况下表示单键。还提供了用于预防或在体内装置中减少生物膜形成和/或从体内装置去除生物膜，其中所述生物膜包含丙酸杆菌属的细菌或由其构成。此外，提供了一种体外装置，其被涂覆和/或加载一种或多种如上所定义的化合物。

2. 发明申请

WO2009103500A1 MEANS AND METHODS FOR CONTROLLING COMMENSALES 审中-公开
标题翻译：用于控制通信的手段和方法
公开(公告)号：WO2009103500A1
公开(公告)日：2009-08-27
申请号：PCT/EP2009/001135
申请日：2009-02-18
申请人： B.R.A.I.N. , DECHERT, Ute , ECK, Jürgen
发明人： DECHERT, Ute , ECK, Jürgen
IPC分类号： A61K8/35 , A61Q19/10 , A61P17/10 , A61Q19/00
CPC分类号： A61K8/35 , A61L27/54 , A61L29/16 , A61L31/16 , A61L2300/404 , A61Q17/005
摘要： The present invention relates to a cosmetic composition for the cleaning of the skin, said composition comprising or consisting of one or more compounds of formula (I) wherein (formula II) represents a single bond or double bond; R 1 and R 2 are independently selected from H, linear or branched C 1 to C 4 alkyl, linear or branched C 1 to C 4 alkenyl, linear or branched C 1 to C 4 alkinyl, and linear or branched C 1 to C 4 alkanoyl; R 4 is selected from H, linear or branched C 1 to C 4 alkyl, linear or branched C 1 to C 4 alkenyl, and linear or branched C 1 to C 4 alkinyl; and R 3 and R 5 are independently selected from H, OH and halogen, or R 3 and R 5 together are O to form an epoxid, wherein (formula II) represents a single bond in case R 3 and R 5 together are O. Also provided are means and methods for the prevention or reduction of biofilm formation on an intracorporeal device and/or for the removal of biofilm from an intracorporeal device, wherein said biofilm comprises or consists of bacteria of the genus Propionibacterium. Furthermore provided is an intracorporeal device which is coated and/or loaded with one or more compounds as defined above.
摘要翻译：本发明涉及一种用于清洁皮肤的化妆品组合物，所述组合物包含一种或多种式（I）化合物或由其组成，其中（式II）表示单键或双键; R 1和R 2独立地选自H，直链或支链C 1至C 4烷基，直链或支链C 1至C 4烯基，直链或支链C 1至C 4炔基，和直链或支链C 1至C 4烷酰基; R4选自H，直链或支链C1至C4烷基，直链或支链C1至C4烯基，直链或支链C1至C4炔基; 并且R 3和R 5独立地选自H，OH和卤素，或者R 3和R 5一起为O以形成环氧化物，其中（式II）在情况R3和R5一起为O时表示单键。还提供了手段和方法用于预防或减少在体内装置上生物膜形成和/或从体内装置中除去生物膜，其中所述生物膜包含丙酸杆菌属的细菌或由其构成。此外，提供了一种体外装置，其被涂覆和/或加载一种或多种如上所定义的化合物。

3. 发明申请

WO2009103500A8 MEANS AND METHODS FOR CONTROLLING COMMENSALES 审中-公开
标题翻译：用于控制通信的手段和方法
公开(公告)号：WO2009103500A8
公开(公告)日：2009-12-03
申请号：PCT/EP2009001135
申请日：2009-02-18
申请人： B R A I N , DECHERT UTE , ECK JUERGEN , KROHN MICHAEL
发明人： DECHERT UTE , ECK JUERGEN , KROHN MICHAEL
IPC分类号： A61K8/35 , A61P17/10 , A61Q19/00 , A61Q19/10
CPC分类号： A61K8/35 , A61L27/54 , A61L29/16 , A61L31/16 , A61L2300/404 , A61Q17/005
摘要： The present invention relates to a cosmetic composition for the cleaning of the skin, said composition comprising or consisting of one or more compounds of formula (I) wherein (formula II) represents a single bond or double bond; R1 and R2 are independently selected from H, linear or branched C1 to C4 alkyl, linear or branched C1 to C4 alkenyl, linear or branched C1 to C4 alkinyl, and linear or branched C1 to C4 alkanoyl; R4 is selected from H, linear or branched C1 to C4 alkyl, linear or branched C1 to C4 alkenyl, and linear or branched C1 to C4 alkinyl; and R3 and R5 are independently selected from H, OH and halogen, or R3 and R5 together are O to form an epoxid, wherein (formula) represents a single bond in case R3 and R5 together are O. Also provided are means and methods for the prevention or reduction of biofilm formation on an intracorporeal device and/or for the removal of biofilm from an intracorporeal device, wherein said biofilm comprises or consists of bacteria of the genus Propionibacterium. Furthermore provided is an intracorporeal device which is coated and/or loaded with one or more compounds as defined above.
摘要翻译：本发明涉及一种用于清洁皮肤的化妆品组合物，所述组合物包含一种或多种式（I）化合物或由其组成，其中（式II）表示单键或双键; R 1和R 2独立地选自H，直链或支链C 1至C 4烷基，直链或支链C 1至C 4烯基，直链或支链C 1至C 4炔基，和直链或支链C 1至C 4烷酰基; R4选自H，直链或支链C1至C4烷基，直链或支链C1至C4烯基，直链或支链C1至C4炔基; 并且R 3和R 5独立地选自H，OH和卤素，或者R 3和R 5一起为O以形成环氧化物，其中（式）在R3和R5一起为O的情况下表示单键。还提供了用于预防或减少在体内装置上生物膜形成和/或从体内装置中除去生物膜，其中所述生物膜由丙酸杆菌属细菌组成或由其组成。此外，提供了一种体外装置，其被涂覆和/或加载一种或多种如上所定义的化合物。

4. 发明申请

WO2009103501A1 MEANS AND METHODS FOR CONTROLLING COMMENSALES 审中-公开
标题翻译：用于控制通信的手段和方法
公开(公告)号：WO2009103501A1
公开(公告)日：2009-08-27
申请号：PCT/EP2009/001136
申请日：2009-02-18
申请人： B.R.A.I.N. , DECHERT, Ute , ECK, Jürgen , KROHN, Michael , ZEECK, Axel
发明人： DECHERT, Ute , ECK, Jürgen , KROHN, Michael , ZEECK, Axel
IPC分类号： A61K8/49 , A61Q19/00 , A61P17/10
CPC分类号： A61Q17/005 , A61K8/4973 , A61K8/498 , A61L27/34 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/20 , A61L2300/404
摘要： This invention relates to a cosmetic composition comprising or consisting of one or more compounds selected from the compounds of formulae (A) and (B) wherein ---- represents a single bond or double bond; R 1 in formula (A) and R 1 in formula (B) are selected from H, linear or branched C 1 to C 4 alkyl, linear or branched C 1 to C 4 alkenyl, linear or branched C 1 to C 4 alkinyl, and linear or branched C 1 to C 4 alkanoyl; R 3 in formula (A) and R 3 in formula (B) are selected from H, linear or branched C 1 to C 4 alkyl, linear or branched C 1 to C 4 alkenyl, and linear or branched C 1 to C 4 alkinyl; R 2 and R 4 in formula (A) are independently selected from H, OH and halogen, or R 2 and R 4 together are O to form an epoxid, wherein ---- represents a single bond in case R 2 and R 4 together are O; and R 2 and R 4 in formula (B) are defined as R 2 and R 4 in formula (A), respectively. Preferably, said cosmetic composition is for the cleaning of the skin. Also provided are means and methods for the prevention or reduction of biofilm formation on an intracorporeal device and/or for the removal of biofilm from an intracorporeal device, wherein said biofilm comprises or consists of bacteria of the genus Propionibacterium . Furthermore provided is an intracorporeal device which is coated and/or loaded with one or more compounds as defined above.
摘要翻译：本发明涉及包含一种或多种选自式（A）和（B）的化合物的化合物或由其组成的化妆品组合物，其中----表示单键或双键; 式（A）中的R 1和式（B）中的R 1选自H，直链或支链C 1至C 4烷基，直链或支链C 1至C 4烯基，直链或支链C 1至C 4炔基，以及直链或支链C 1至C 4烷酰基 ; 式（A）中的R 3和式（B）中的R 3选自H，直链或支链C 1至C 4烷基，直链或支链C 1至C 4烯基，以及直链或支链C 1至C 4炔基; 式（A）中的R 2和R 4独立地选自H，OH和卤素，或者R 2和R 4一起为O以形成环氧化物，其中，在R 2和R 4一起为O的情况下，表示单键。式（B）中的R 2和R 4分别定义为式（A）中的R 2和R 4。优选地，所述化妆品组合物用于清洁皮肤。还提供了用于预防或减少在体内装置上生物膜形成和/或从体内装置中除去生物膜的手段和方法，其中所述生物膜包含丙酸杆菌属的细菌或由其构成。此外，提供了一种体外装置，其被涂覆和/或加载一种或多种如上所定义的化合物。

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