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1. 发明申请

WO2010025383A1 EXPANDABLE MICROSPHERES AND METHODS OF MAKING AND USING THE SAME 审中-公开
标题翻译：可膨胀的微球及其制造和使用方法
公开(公告)号：WO2010025383A1
公开(公告)日：2010-03-04
申请号：PCT/US2009/055390
申请日：2009-08-28
申请人： INTERNATIONAL PAPER COMPANY , HONG, Yaoliang , MOHAN, Kosaraju Krishna , FROASS, Peter, M. , FAGAN, Mark , ANDERSON, Christopher, D. , BOYARS, Bryan , DANIELS, Eric, Scott , DIMONIE, Victoria, Laurentia , SUDOL, Edward, David , KLEIN, Andrew
发明人： HONG, Yaoliang , MOHAN, Kosaraju Krishna , FROASS, Peter, M. , FAGAN, Mark , ANDERSON, Christopher, D. , BOYARS, Bryan , DANIELS, Eric, Scott , DIMONIE, Victoria, Laurentia , SUDOL, Edward, David , KLEIN, Andrew
IPC分类号： C08F259/06 , C08J9/20 , D21H21/54
CPC分类号： C08L27/08 , B01J13/14 , C08L33/20 , D21H21/54
摘要： Expandable microspheres formed by suspension polymerization using a shot growth method are provided. The microspheres are formed of a continuous, gas impermeable shell surrounding a blowing agent. The shell includes a first polymer layer formed from primary monomers and a second layer that includes a chemically reactive monomer or a high Tg monomer. To form the microspheres, the primary monomers are polymerized in a reaction vessel to an approximate 90% polymerization, at which time a secondary monomer that is either a monomer having a Tg of at least 85 °C or a chemically reactive monomer, is added to the reaction vessel to drive the polymerization reaction to completion. The outer layer thus contains either a larger amount of the high Tg monomer or a chemically reactive monomer that possesses the ability to covalently bond a cationic species. The microspheres may be used in papermaking processes to increase the paper bulk.
摘要翻译：提供了通过使用喷射生长法的悬浮聚合形成的可发泡微球。微球由围绕发泡剂的连续不透气壳形成。壳包括由初级单体形成的第一聚合物层和包含化学反应性单体或高Tg单体的第二层。为了形成微球，将初级单体在反应容器中聚合至约90％的聚合，此时将作为Tg至少为85℃的单体的二次单体或化学反应性单体加入到反应容器驱动聚合反应完成。因此，外层含有较大量的高Tg单体或具有共价键合阳离子物质的能力的化学反应性单体。微球可用于造纸过程中以增加纸张体积。

2. 发明申请

WO2006069349A2 CELL-LOADED PROSTHESES FOR REGENERATIVE INTRALUMINAL APPLICATIONS 审中-公开
标题翻译：细胞负载假体再生颅内应用
公开(公告)号：WO2006069349A2
公开(公告)日：2006-06-29
申请号：PCT/US2005/046926
申请日：2005-12-22
申请人： CYTORI THERAPEUTICS, INC. , DANIELS, Eric , STREM, Brian , RILEY, Susan, Lynn , DE EMEDIO, Mike , FRASER, John, K. , HEDRICK, Marc, H.
发明人： DANIELS, Eric , STREM, Brian , RILEY, Susan, Lynn , DE EMEDIO, Mike , FRASER, John, K. , HEDRICK, Marc, H.
CPC分类号： A61L27/3839 , A61F2/90 , A61F2250/0067 , A61L27/3804
摘要： Cell-loaded devices or prostheses having various applications such as insertion into body passages are disclosed. The prostheses include cell carrier portions which are compatible with living tissue and which are loaded with therapeutic cell populations, and the prostheses can be applied within or replace one or more of narrow segments, environments which may be difficult to access or luminal areas of the body such as parts of blood vessels. In the context of blood vessels, the cell-loaded devices or prostheses can line or otherwise treat with therapeutic cell populations inner walls of damaged blood vessels and surrounding parenchyma or other organs.
摘要翻译：公开了具有各种应用的细胞负载装置或假体，例如插入身体通道中。假体包括与活组织兼容的细胞载体部分，并且载有治疗细胞群体，并且假体可以应用于或替代一个或多个狭窄部分，难以接近的环境或身体腔区域如部分血管。在血管的情况下，装载细胞的装置或假体可以与治疗细胞群受损血管的内壁以及周围的薄壁组织或其他器官一致或以其他方式治疗。

3. 发明申请

WO2004074457A3 METHODS OF USING ADIPOSE TISSUE-DERIVED CELLS IN THE TREATMENT OF CARDIOVASCULAR CONDITIONS 审中-公开
标题翻译：将ADIPOSE TISSUE衍生细胞用于治疗心血管事件的方法
公开(公告)号：WO2004074457A3
公开(公告)日：2006-05-18
申请号：PCT/US2004005117
申请日：2004-02-20
申请人： MACROPORE BIOSURGERY INC , FRASER JOHN K , HEDRICK MARC H , ZHU MIN , STREM BRIAN M , DANIELS ERIC , WULUR ISABELLA
发明人： FRASER JOHN K , HEDRICK MARC H , ZHU MIN , STREM BRIAN M , DANIELS ERIC , WULUR ISABELLA
IPC分类号： A01N63/00 , C12N5/00 , C12N5/071 , C12N5/0775
CPC分类号： C12N5/0667 , A61K35/12 , A61L27/3804 , A61L27/3839 , C12N5/069 , C12N2506/1384
摘要： Cells present in processed lipoaspirate tissue are used to treat patients, including patients with cardiovascular conditions, diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in processed lipoaspirate are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic cardiovascular benefit.
摘要翻译：存在于加工的脂肪抽吸组织中的细胞用于治疗患者，包括患有心血管病症，疾病或病症的患者。治疗患者的方法包括加工脂肪组织以将从脂肪组织获得的浓缩量的干细胞输送给患者。所述方法可以在封闭系统中实施，使得干细胞在施用于患者之前不暴露于外部环境。因此，在优选的方法中，存在于加工的lipoaspirate中的细胞与用于促进，产生或支持治疗性心血管益处所必需的这种添加剂一起直接放置在受体中。

4. 发明申请

WO2006014162A2 METHODS OF USING REGENERATIVE CELLS IN THE TREATMENT OF RENAL DISEASES AND DISORDERS 审中-公开
标题翻译：使用再生细胞治疗肾脏疾病和病症的方法
公开(公告)号：WO2006014162A2
公开(公告)日：2006-02-09
申请号：PCT/US2004/021549
申请日：2004-07-01
申请人： MACROPORE BIOSURGERY INC. , HEDRICK, Marc, H. , FRASER, John, K. , DANIELS, Eric
发明人： HEDRICK, Marc, H. , FRASER, John, K. , DANIELS, Eric
IPC分类号： A61K48/00
CPC分类号： C12N5/0691 , A61K35/28 , A61K45/06 , C12N5/0667 , C12N5/0692 , A61K2300/00
摘要： Cells present in processed lipoaspirate tissue are used to treat patients, including patients with renal conditions, diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in processed lipoaspirate are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic renal benefit.
摘要翻译：处理过的脂肪抽出物组织中存在的细胞用于治疗患者，包括患有肾病，疾病或病症的患者。治疗患者的方法包括处理脂肪组织以将从脂肪组织获得的浓缩量的干细胞递送给患者。该方法可以在封闭系统中实施，以便干细胞在施用于患者之前不暴露于外部环境。因此，在优选的方法中，存在于处理过的脂肪抽出物中的细胞与促进，产生或支持治疗性肾益处所必需的这些添加剂一起直接置于接受者体内。

5. 发明申请

WO2013028644A2 SOLAR SYNCHRONIZED LOADS FOR PHOTOVOLTAIC SYSTEMS 审中-公开
标题翻译：太阳能同步系统的同步负载
公开(公告)号：WO2013028644A2
公开(公告)日：2013-02-28
申请号：PCT/US2012/051639
申请日：2012-08-20
申请人： ROBERT BOSCH GMBH , DANIELS, Eric , SAUSSELE, John
发明人： DANIELS, Eric , SAUSSELE, John
IPC分类号： H02J1/00 , H02J9/00 , H02M7/44 , H02M7/04
CPC分类号： H02J3/383 , H02J3/14 , H02J7/35 , H02J2003/143 , H02M7/44 , Y02B10/14 , Y02B70/3266 , Y02E10/563 , Y02E10/566 , Y04S20/242 , Y10T307/344 , Y10T307/406 , Y10T307/707
摘要： An electrical power supply arrangement includes a solar power device that converts sunlight into DC electrical power. A DC load runs on the DC current electrical power. The DC load may be controlled or adjusted to consume a maximum amount of the electrical output of the solar power device. A DC-to-AC converter converts the DC electrical power into AC electrical power. A controller enables the DC-to-AC converter to receive a portion of the DC current electrical power from the solar power device only if all of the DC current electrical power cannot be consumed by the DC load.
摘要翻译：电力供应装置包括将太阳光转换为直流电力的太阳能发电装置。直流负载运行在直流电流上。可以控制或调整DC负载以消耗太阳能发电装置的最大电力输出量。 DC-AC转换器将DC电力转换成AC电力。控制器使DC-AC转换器能够仅在所有直流电功率不能被直流负载消耗的情况下从太阳能发电装置接收一部分直流电力电力。

6. 发明申请

WO2006127007A3 METHODS OF USING ADIPOSE TISSUE-DERIVED CELLS IN THE TREATMENT OF CARDIOVASCULAR CONDITIONS 审中-公开
标题翻译：将ADIPOSE TISSUE衍生细胞用于治疗心血管事件的方法
公开(公告)号：WO2006127007A3
公开(公告)日：2009-04-16
申请号：PCT/US2005018605
申请日：2005-05-25
申请人： CYTORI THERAPEUTICS INC , FRASER JOHN K , HEDRICK MARC H , ZHU MIN , STREM BRIAN M , DANIELS ERIC , WULUR ISABELLA
发明人： FRASER JOHN K , HEDRICK MARC H , ZHU MIN , STREM BRIAN M , DANIELS ERIC , WULUR ISABELLA
IPC分类号： A61K35/34 , C12N5/00 , A61K35/12 , A61P9/02 , C12N5/071 , C12N5/0775
CPC分类号： C12N5/0667 , A61K35/12
摘要： Adipose derived regenerative cells are used to treat patients, including patients with cardiovascular conditions, diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells, e.g., stem and/or progenitor cells, obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, adipose derived regenerative cells are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic cardiovascular benefit.
摘要翻译：脂肪来源的再生细胞用于治疗患者，包括患有心血管疾病，疾病或病症的患者。治疗患者的方法包括加工脂肪组织以将从脂肪组织获得的浓缩量的再生细胞例如干细胞和/或祖细胞递送给患者。所述方法可以在封闭系统中实施，使得干细胞在施用于患者之前不暴露于外部环境。因此，在优选的方法中，将脂肪来源的再生细胞与促进，产生或支持治疗性心血管益处所必需的这些添加剂一起直接放入受体中。

7. 发明申请

WO2004074457A2 METHODS OF USING ADIPOSE TISSUE-DERIVED CELLS IN THE TREATMENT OF CARDIOVASCULAR CONDITIONS 审中-公开
标题翻译：将ADIPOSE TISSUE衍生细胞用于治疗心血管事件的方法
公开(公告)号：WO2004074457A2
公开(公告)日：2004-09-02
申请号：PCT/US2004/005117
申请日：2004-02-20
申请人： MACROPORE BIOSURGERY, INC. , FRASER, John, K. , HEDRICK, Marc, H. , ZHU, Min , STREM, Brian, M. , DANIELS, Eric , WULUR, Isabella
发明人： FRASER, John, K. , HEDRICK, Marc, H. , ZHU, Min , STREM, Brian, M. , DANIELS, Eric , WULUR, Isabella
IPC分类号： C12N
CPC分类号： C12N5/0667 , A61K35/12 , A61L27/3804 , A61L27/3839 , C12N5/069 , C12N2506/1384
摘要： Cells present in processed lipoaspirate tissue are used to treat patients, including patients with cardiovascular conditions, diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in processed lipoaspirate are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic cardiovascular benefit.
摘要翻译：存在于加工的脂肪抽吸组织中的细胞用于治疗患者，包括患有心血管病症，疾病或病症的患者。治疗患者的方法包括加工脂肪组织以将从脂肪组织获得的浓缩量的干细胞输送给患者。所述方法可以在封闭系统中实施，使得干细胞在施用于患者之前不暴露于外部环境。因此，在优选的方法中，存在于加工的lipoaspirate中的细胞与用于促进，产生或支持治疗性心血管益处所必需的这种添加剂一起直接放置在受体中。

8. 发明申请

WO2014035432A2 DYNAMIC DISTRIBUTED-SENSOR NETWORK FOR FORECASTING EXTERNAL EVENTS 审中-公开
标题翻译：用于预测外部事件的动态分布式传感器网络
公开(公告)号：WO2014035432A2
公开(公告)日：2014-03-06
申请号：PCT/US2012/053502
申请日：2012-08-31
申请人： NEST LABS, INC. , FILSON, John, B. , DANIELS, Eric, B. , MITTLEMAN, Adam , NELMES, Sierra, L. , MATSUOKA, Yoky
发明人： FILSON, John, B. , DANIELS, Eric, B. , MITTLEMAN, Adam , NELMES, Sierra, L. , MATSUOKA, Yoky
IPC分类号： G06Q10/08
CPC分类号： G06Q10/08
摘要： Systems and methods for forecasting events can be provided. A measurement database can store sensor measurements, each having been provided by a non-portable electronic device with a primary purpose unrelated to collecting measurements from a type of sensor that collected the measurement. A measurement set identifier can select a set of measurements. The electronic devices associated with the set of measurements can be in close geographical proximity relative to their geographical proximity to other devices. An inter-device correlator can access the set and collectively analyze the measurements. An event detector can determine whether an event occurred. An event forecaster can forecast a future event property. An alert engine can identify one or more entities to be alerted of the future event property, generate at least one alert identifying the future event property, and transmit the at least one alert to the identified one or more entities.
摘要翻译：可以提供用于预测事件的系统和方法。测量数据库可以存储传感器测量值，每个传感器测量值都由非便携式电子设备提供，其主要目的与收集来自收集测量值的传感器类型的测量值无关。测量集标识符可以选择一组测量值。与该组测量相关联的电子设备相对于其与其他设备的地理接近度可以处于接近的地理接近度。设备间相关器可以访问该设备并共同分析测量结果。事件检测器可以确定事件是否发生。事件预报员可以预测未来的事件属性。警报引擎可以识别要提醒未来事件属性的一个或多个实体，生成识别未来事件属性的至少一个警报，并且将至少一个警报传送给所识别的一个或多个实体。

9. 发明申请

WO2006069349A3 CELL-LOADED PROSTHESES FOR REGENERATIVE INTRALUMINAL APPLICATIONS 审中-公开
标题翻译：用于再生血管内应用的细胞负载预测
公开(公告)号：WO2006069349A3
公开(公告)日：2007-08-09
申请号：PCT/US2005046926
申请日：2005-12-22
申请人： CYTORI THERAPEUTICS INC , DANIELS ERIC , STREM BRIAN , RILEY SUSAN LYNN , DE EMEDIO MIKE , FRASER JOHN K , HEDRICK MARC H
发明人： DANIELS ERIC , STREM BRIAN , RILEY SUSAN LYNN , DE EMEDIO MIKE , FRASER JOHN K , HEDRICK MARC H
IPC分类号： A61F2/02 , C12N5/00
CPC分类号： A61L27/3839 , A61F2/90 , A61F2250/0067 , A61L27/3804
摘要： Cell-loaded devices or prostheses having various applications such as insertion into body passages are disclosed. The prostheses include cell carrier portions which are compatible with living tissue and which are loaded with therapeutic cell populations, and the prostheses can be applied within or replace one or more of narrow segments, environments which may be difficult to access or luminal areas of the body such as parts of blood vessels. In the context of blood vessels, the cell-loaded devices or prostheses can line or otherwise treat with therapeutic cell populations inner walls of damaged blood vessels and surrounding parenchyma or other organs.
摘要翻译：公开了具有诸如插入到体通道中的各种应用的装有电池的装置或假体。假体包括与活组织相容并且装有治疗细胞群体的细胞载体部分，并且假体可以施用于狭窄部分或可能难以进入的环境或身体的腔内区域中的一个或多个如血管部分。在血管的背景下，细胞负载装置或假体可以与治疗细胞群体受损的血管和周围的实质或其他器官的内壁相交或以其它方式治疗。

10. 发明申请

WO2006127007A2 METHODS OF USING ADIPOSE TISSUE-DERIVED CELLS IN THE TREATMENT OF CARDIOVASCULAR CONDITIONS 审中-公开
标题翻译：将ADIPOSE TISSUE衍生细胞用于治疗心血管事件的方法
公开(公告)号：WO2006127007A2
公开(公告)日：2006-11-30
申请号：PCT/US2005/018605
申请日：2005-05-25
申请人： MACROPORE BIOSURGERY INC. , FRASER, John, K. , HEDRICK, Marc, H. , ZHU, Min , STREM, Brian, M. , DANIELS, Eric , WULUR, Isabella
发明人： FRASER, John, K. , HEDRICK, Marc, H. , ZHU, Min , STREM, Brian, M. , DANIELS, Eric , WULUR, Isabella
IPC分类号： A61K35/34 , C12N5/08
CPC分类号： C12N5/0667 , A61K35/12
摘要： Adipose derived regenerative cells are used to treat patients, including patients with cardiovascular conditions, diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells, e.g., stem and/or progenitor cells, obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, adipose derived regenerative cells are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic cardiovascular benefit.
摘要翻译：脂肪来源的再生细胞用于治疗患者，包括患有心血管疾病，疾病或病症的患者。治疗患者的方法包括加工脂肪组织以将从脂肪组织获得的浓缩量的再生细胞例如干细胞和/或祖细胞递送给患者。所述方法可以在封闭系统中实施，使得干细胞在施用于患者之前不暴露于外部环境。因此，在优选的方法中，将脂肪来源的再生细胞与促进，产生或支持治疗性心血管益处所必需的这些添加剂一起直接放入受体中。

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