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1. 发明申请

WO2023281419A2 ADMINISTRATION OF NAKED NUCLEIC ACID MOLECULE 审中-公开
公开(公告)号：WO2023281419A2
公开(公告)日：2023-01-12
申请号：PCT/IB2022/056252
申请日：2022-07-06
申请人： DAICEL CORPORATION
发明人： SAKAGUCHI, Naoki , YAMASHITA, Kunihiko
IPC分类号： A61M5/48 , C12M1/42
摘要： Provided herein is a method of administering a naked nucleic acid molecule to a subject. The method may include injecting the naked nucleic acid molecule to the subject, wherein the injecting exhibits a bi-phasic injection profile comprising a first phase and a second phase, the second phase being after the first phase, and the bi-phasic injection profile has (i) at least two peaks within 15 msec from the injecting, (ii) the first peak of at least 2 MPa, or (iii) the highest peak of the second phase of the bi-phasic injection within 30 msec from the injecting.

2. 发明申请

WO2013176064A1 GAS GENERATOR 审中-公开
标题翻译：气体发电机
公开(公告)号：WO2013176064A1
公开(公告)日：2013-11-28
申请号：PCT/JP2013/063874
申请日：2013-05-14
申请人： DAICEL CORPORATION
发明人： UKITA, Shinichiro , MATSUDA, Naoki
IPC分类号： B60R21/264
CPC分类号： C06D5/00 , B60R21/2644 , B60R2021/2648
摘要： The present invention provides a gas generator including: • a housing (13) including an inner cylindrical member (24) for defining an ignition chamber (19) therein, • a first combustion chamber (30) and a second combustion chamber (40) provided outside the inner cylindrical member and being charged with the first and second gas generating agents (32,42), respectively, • a plenum chamber (50) located between the first combustion chamber and the second combustion chamber and being defined by the partition member, • a first communication nozzle (80) and a second communication nozzle (82) provided in the inner cylindrical member, • an axial position of the first communication nozzle being adjusted to be farther away from the plenum chamber than an axial position of the second communication nozzle, a first gas generating agent to be burn up earlier than a second gas generating agent.
摘要翻译：本发明提供一种气体发生器，包括：包括用于在其中限定点火室（19）的内圆柱形构件（24）的壳体（13）。第一燃烧室（30）和第二燃烧室（40），其分别设置在所述内圆柱形构件的外部并且分别装载有所述第一和第二气体发生剂（32,42）。位于第一燃烧室和第二燃烧室之间并由分隔构件限定的增压室（50）。第一连通喷嘴（80）和设置在所述内圆柱形构件中的第二连通喷嘴（82）。第一连通喷嘴的轴向位置被调节为比第二连通喷嘴的轴向位置更远离充气室，第一气体发生剂比第二气体发生剂早燃烧。

3. 发明申请

WO2013161431A1 GAS GENERATOR 审中-公开
标题翻译：气体发电机
公开(公告)号：WO2013161431A1
公开(公告)日：2013-10-31
申请号：PCT/JP2013/057335
申请日：2013-03-11
申请人： DAICEL CORPORATION
发明人： UKITA, Shinichiro , HANANO, Teppei , YAMAZAKI, Masayuki
IPC分类号： B60R21/264 , B60R21/26
CPC分类号： C06D5/00 , B60R21/26 , B60R2021/26011 , B60R2021/26076
摘要： The present invention provides a gas generator including a housing provided with a diffuser shell and a closure shell, an ignition device, the diffuser shell being in a substantially cup-like shape and having an annular bent portion obtained by bending a circumferential wall portion at an opening inwardly, the closure shell being in a substantially annular shape having a annular plate portion that includes a annular curved portion projecting toward the inside of the housing, the ignition device being fixed to a central hole in the annular plate portion with a resin, an inner circumferential part of the annular plate portion in the closure shell abutting against the resin, an outer circumferential part of the annular plate portion abutting against and being fixed to the annular bent portion of the diffuser shell.
摘要翻译：本发明提供一种气体发生器，其包括设置有扩散器壳体和封闭壳体的壳体，点火装置，所述扩散器壳体基本上为杯状形状，并且具有环形弯曲部分，该环形弯曲部分通过在所述封闭壳体是向内开口的，所述封闭壳体具有环形板部分，所述环形板部分包括朝向所述壳体内部突出的环形弯曲部分，所述点火装置用树脂固定到所述环形板部分中的中心孔，封闭壳体中环形板部分的内圆周部分抵靠树脂，环形板部分的外圆周部分邻接并固定到扩散器壳体的环形弯曲部分。

4. 发明申请

WO2013161430A1 GAS GENERATOR 审中-公开
标题翻译：气体发电机
公开(公告)号：WO2013161430A1
公开(公告)日：2013-10-31
申请号：PCT/JP2013/057334
申请日：2013-03-11
申请人： DAICEL CORPORATION
发明人： KOBAYASHI, Tomoharu
IPC分类号： B60R21/264
CPC分类号： F02G3/00 , B60R21/2644 , B60R2021/26029 , F42B3/04
摘要： The present invention provides a gas generator including a housing, an inner cylindrical member defining an ignition chamber therein and a combustion chamber outside, an ignition device disposed inside the ignition chamber, a solid gas generating agent charged in the combustion chamber, the inner cylindrical member including, a plurality of nozzles provided in a circumferential wall to communicate the ignition chamber with the combustion chamber, a guide member provided at least in the outer side or the inner side of the circumferential wall, so that combustion products from the ignition chamber is discharged from the nozzles and guided towards a bottom plate of the housing, the combustion chamber defined by the circumferential wall of the inner cylindrical member and the circumferential wall portion of the housing, an outlet from the inner cylindrical member being formed closer to the bottom plate than to the gas discharge port.
摘要翻译：本发明提供一种气体发生器，包括壳体，在其中限定点火室的内圆柱形构件和在外部的燃烧室，设置在点火室内的点火装置，装在燃烧室中的固体气体发生剂，内圆柱形构件包括设置在周壁中的多个喷嘴以使点火室与燃烧室连通，至少设置在周壁的外侧或内侧的引导构件，使得来自点火室的燃烧产物被排出从喷嘴引导并引导到壳体的底板，由内圆柱形构件的圆周壁和壳体的周壁部分限定的燃烧室，从内圆柱形构件的出口形成得比底板更靠近底板，到排气口。

5. 发明申请

WO2013133349A1 GAS GENERATOR FOR RESTRAINING DEVICE 审中-公开
标题翻译：用于限制装置的气体发生器
公开(公告)号：WO2013133349A1
公开(公告)日：2013-09-12
申请号：PCT/JP2013/056219
申请日：2013-02-28
申请人： DAICEL CORPORATION
发明人： OZAKI, Nobuhiko , YAMAZAKI, Masayuki
IPC分类号： B60R21/264
CPC分类号： C06D5/00 , B60R21/261 , B60R21/2644
摘要： The present invention provides: a gas generator for a restraining device including, a housing (10) having an ignition device (12) and a diffuser portion (14) and a gas generating agent charged in an inner space of the housing, a plate-like partition member (20) being disposed so as to incline regarding a long axis (X) of the housing, thereby dividing the inner space into a gas generating agent charging space (38) and a gas flow channel space (40), both of the edges of the partition member (20) being abutted against an inner circumferential surface of the housing, a cross-sectional area of the gas generating agent charging space (38) decreasing from the ignition device side to the diffuser portion side, a cross-sectional area of the gas flow channel space (40) increasing from the ignition device side to the diffuser portion side.
摘要翻译：本发明提供一种用于约束装置的气体发生器，包括：具有点火装置（12）和扩散器部分（14）的壳体（10）和装在壳体的内部空间中的气体发生剂，（20）被设置为关于壳体的长轴（X）倾斜，从而将内部空间分成气体发生剂充电空间（38）和气体流动通道空间（40），两者均为分隔构件（20）的边缘抵靠壳体的内周面，气体发生剂充电空间（38）的从点火装置侧向扩散器部侧减小的横截面积，气体流路空间40的截面积从点火装置侧向扩散部侧增加。

6. 发明申请

WO2013061717A1 GAS GENERATOR FOR RESTRAINING DEVICE 审中-公开
标题翻译：用于限制装置的气体发生器
公开(公告)号：WO2013061717A1
公开(公告)日：2013-05-02
申请号：PCT/JP2012/074310
申请日：2012-09-14
申请人： DAICEL CORPORATION , KOBAYASHI, Tomoharu , NUMOTO, Kenji
发明人： KOBAYASHI, Tomoharu , NUMOTO, Kenji
IPC分类号： B60R21/264
CPC分类号： B60R21/2644 , B60R2021/26076 , B60R2021/2648
摘要： The present invention provides a gas generator for a restraining device, including: • a housing (16) formed by a diffuser shell (12) having a gas discharge port (38) and a closure shell (14), • an ignition device chamber (18) in which an ignition device (24) is accommodated, and a combustion chamber (20) in which a gas generating agent (28) is accommodated, being defined inside the housing, • the ignition device chamber being defined inside an inner tube (22) disposed in the housing, and the combustion chamber being de fined outside the inner tube, • the inner tube including, • openings on both ends being fixed to a bottom surface and a top surface of the housing, • a flame-transferring hole (52) being formed in a circumferential wall portion to communicate the ignition device chamber with the combustion chamber, and • a reduced strength portion (56) being provided in the circumferential wall portion between the flame-transferring hole and the top surface of the housing.
摘要翻译：本发明提供一种用于约束装置的气体发生器，包括：由具有气体排出口（38）和封闭壳（14）的扩散器外壳（12）形成的壳体（16）。其中容纳有点火装置（24）的点火装置室（18）和容纳有气体发生剂（28）的燃烧室（20）被限定在壳体内部。所述点火装置室被限定在设置在所述壳体内的内管（22）的内部，并且所述燃烧室被限定在所述内管的外部。内管包括。两端的开口固定在壳体的底面和顶面上。在圆周壁部分中形成有火焰传递孔（52），以将点火装置室与燃烧室连通。减震强度部分（56）设置在所述火焰传送孔和所述壳体的顶表面之间的周壁部分中。

7. 发明申请

WO2013027587A1 THRUST NEUTRAL INFLATOR FOR AN AIR BAG MODULE 审中-公开
标题翻译：用于空气袋模块的中性穿透器
公开(公告)号：WO2013027587A1
公开(公告)日：2013-02-28
申请号：PCT/JP2012/070281
申请日：2012-08-02
申请人： DAICEL CORPORATION , IWAKIRI, Toshiro
发明人： IWAKIRI, Toshiro
IPC分类号： B60R21/217
CPC分类号： B60R21/2171 , B60R21/261
摘要： The present invention provides a gas generator assembly (1) for a restraining device, including: a gas generator (10) including, a housing (12) a cup-shaped diffuser (16) having a gas discharge port (14) and being attached to one end of the housing, a cup- shaped gas flow controller (20) assembled with the gas generator, an outer diameter of the diffuser being smaller than an outer diameter of the housing the gas flow controller having a bottom surface (24), a circumferential wall portion (23) and an opening portion (22), the bottom surface being provided with a communication hole (26) for allowing passage of gas flow, the circumferential wall portion of the gas flow controller surrounding the gas discharge port, the gas flow controller being attached such as to form a gap between a peripheral edge of the opening portion and the housing, gas, discharged from the gas discharge port colliding the circumferential wall portion of the gas flow controller, the gas flow being divided into both sides in the axial (X) direction to flow out from the gap and the communication hole.
摘要翻译：本发明提供了一种用于约束装置的气体发生器组件（1），包括：气体发生器（10），包括：壳体（12），具有气体排出口（14）的杯状扩散器（16）壳体的一端，与气体发生器组装的杯形气体流量控制器（20），扩散器的外径小于壳体的外径，气体流量控制器具有底表面（24），周壁部（23）和开口部（22），底面设置有用于允许气流通过的连通孔（26），围绕气体排出口的气体流量控制器的周壁部分安装气体流量控制器，以在开口部分的周边边缘与壳体之间形成间隙，从气体排出口排出的气体与气体流量控制器的周壁部分相撞，将气体流分为机器人 h侧轴向（X）方向从间隙和连通孔流出。

8. 发明申请

WO2012111727A1 SEAL TAPE FOR GAS GENERATOR 审中-公开
标题翻译：气体发生器密封胶带
公开(公告)号：WO2012111727A1
公开(公告)日：2012-08-23
申请号：PCT/JP2012/053591
申请日：2012-02-09
申请人： DAICEL CORPORATION , HANANO, Teppei , UKITA, Shinichiro
发明人： HANANO, Teppei , UKITA, Shinichiro
IPC分类号： B60R21/262 , B60R21/274 , F16J15/06 , F16K17/14 , B60R21/264
CPC分类号： F16K17/16 , B60R21/2644 , B60R2021/2648 , F16J15/064
摘要： A seal tape (10A), a gas generator for a restraining apparatus using the seal tape, a method for manufacturing a gas generator with such a seal tape. A seal tape closes, from the outside of the gas generator housing, a gas discharge port (113) in a housing. The seal tape includes, a rupture portion (12) for forming a door portion (16), and including a fragile portion (13) and a rupture blocking potion (14) at a tip of the fragile portion (13), a fixing support portion (15) remaining attached to the housing, the door portion (16) bounded by the rupture portion (12) and the fixing support portion (15) being adjusted such that the gas discharge port (113) is entirely open in a case where the door portion (16) is opened.
摘要翻译：密封带（10A），用于使用密封带的约束装置的气体发生器，用这种密封带制造气体发生器的方法。密封带从气体发生器壳体的外部封闭在壳体中的气体排出口（113）。密封带包括用于形成门部分（16）的破裂部分（12），并且在脆弱部分（13）的尖端处包括脆弱部分（13）和破裂阻挡部分（14），固定支撑件保持附着在壳体上的部分（15），由破裂部分（12）和固定支撑部分（15）限定的门部分（16）被调整为使得气体排出口（113）完全打开，门部分（16）打开。

9. 发明申请

WO2023281418A1 PERSONALIZED VACCINE ADMINISTRATION 审中-公开
公开(公告)号：WO2023281418A1
公开(公告)日：2023-01-12
申请号：PCT/IB2022/056251
申请日：2022-07-06
申请人： DAICEL CORPORATION
发明人： SAKAGUCHI, Naoki , YAMASHITA, Kunihiko , TERAI, Kazuhiro
IPC分类号： A61K9/00 , A61K39/00 , A61M5/00
摘要： Provided herein is a method of manufacturing a packaged vaccine personalized to a subject. Also provided is a method of administering a personalized vaccine to a subject. Further provided is an injector having an igniter and a removable cartridge.

10. 发明申请

WO2022133984A1 CURABLE COMPOUND PRODUCT 审中-公开
公开(公告)号：WO2022133984A1
公开(公告)日：2022-06-30
申请号：PCT/CN2020/139307
申请日：2020-12-25
申请人： DAICEL CORPORATION , LIU, Feng
发明人： OKANO, Yoshimichi , NAKATANI, Kouji
IPC分类号： C08G65/40 , C08G65/48 , C08G73/12
摘要： The present invention provides a curable compound product that forms a cured product having excellent heat resistance and high insulating properties by performing heat treatment. The curable compound product of the present disclosure contains a compound represented by Formula (1) below, and a proportion of a group represented by Formula (r-1) below to the sum of the group represented by Formula (r-1) below and a group represented by Formula (r-2) below is 97%or greater. In Formula (1), R 1 and R 2 are identical or different, and each represent the group represented by Formula (r-1) the group represented by Formula (r-2) below: D 1 and D 2 are identical or different, and each represent a single bond or a linking group. L represents a divalent group having a repeating unit containing a structure represented by Formula (I) below and a structure represented by Formula (II) below.

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