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1. 发明授权

US07803034B2 System for moving and positioning an object such as a tool 有权
标题翻译：用于移动和定位诸如工具的对象的系统
公开(公告)号：US07803034B2
公开(公告)日：2010-09-28
申请号：US11692833
申请日：2007-03-28
申请人： Edward C. Camp , Craig Gardner
发明人： Edward C. Camp , Craig Gardner
IPC分类号： B24B41/00
CPC分类号： B24B19/06 , B23Q1/5481 , B24B41/04
摘要： A system for moving and positioning an object such as a tool. The system has a first assembly that has a first rotatable portion that is rotatable about a first axis, and a second assembly that has a second rotatable portion that is rotatable about a second axis that is not coincident with the first axis. The system may include a third assembly that has a third rotatable portion that is rotatable about a third axis that is not coincident with the second axis. The assemblies are coupled such that rotation of the first rotatable portion causes eccentric rotation of the second and third rotatable portions about the first axis. The system also includes a controller for causing one, two or all three of the rotatable portions to rotate, so as to establish a desired position of an object that is coupled to the system.
摘要翻译：用于移动和定位诸如工具的对象的系统。该系统具有第一组件，该第一组件具有可围绕第一轴线旋转的第一可旋转部分，以及第二组件，该第二组件具有可围绕不与第一轴线重合的第二轴线旋转的第二可旋转部分。该系统可以包括具有第三可旋转部分的第三组件，该第三可旋转部分可围绕不与第二轴线重合的第三轴线旋转。组件联接成使得第一可旋转部分的旋转引起第二和第三可旋转部分围绕第一轴的偏心旋转。该系统还包括用于使一个，两个或全部三个可旋转部分旋转的控制器，以便建立耦合到系统的物体的期望位置。

2. 发明授权

US06718189B2 Method and apparatus for non-invasive blood analyte measurement with fluid compartment equilibration 失效
标题翻译：用流体隔室平衡测量非侵入性血液分析物的方法和装置
公开(公告)号：US06718189B2
公开(公告)日：2004-04-06
申请号：US09864774
申请日：2001-05-24
申请人： Mark Rohrscheib , Craig Gardner , Mark R. Robinson
发明人： Mark Rohrscheib , Craig Gardner , Mark R. Robinson
IPC分类号： A61B500
CPC分类号： A61B5/0059 , A61B5/14532 , A61B5/1455 , A61B5/1495 , A61B2562/146
摘要： A method and apparatus for non-invasively measuring the concentration of an analyte, particularly blood analyte in blood. The method utilizes spectrographic techniques in conjunction with means for equilibrating the concentration of the analyte between the vascular system fluid compartment of the test area and the other tissue fluid compartment. An improved optical interface between a sensor probe and a skin surface or tissue surface of the body containing the blood to be analyzed. Multiple readings during the equilibration period are taken and utilized to show the direction and rate of charge of concentration of the analyte in the blood which is useful in optimizing therapeutic response to the collected data.
摘要翻译：用于非侵入性地测量血液中分析物，特别是血液分析物浓度的方法和装置。该方法利用光谱技术结合用于平衡测试区域的血管系统流体隔室与另一组织液体隔室之间的分析物的浓度的装置。传感器探针与包含待分析血液的身体的皮肤表面或组织表面之间的改进的光学界面。在平衡期间进行多次读数并用于显示血液中分析物浓度的方向和速率，这有助于优化对收集的数据的治疗反应。

3. 发明授权

US5127498A Impedance matches mass damper 失效
标题翻译：阻力匹配大型阻尼器
公开(公告)号：US5127498A
公开(公告)日：1992-07-07
申请号：US465034
申请日：1990-01-16
申请人： Richard H. Lyon , Craig Gardner
发明人： Richard H. Lyon , Craig Gardner
IPC分类号： F16F7/104
CPC分类号： F16F7/104
摘要： Damping structural vibrations by applying a multiplicity of discrete untuned passive dampers to a structure. Each passive damper includes a damping element and a damping mass, and the damping element provides damping generally in proportion to the relative velocity occurring between the mass and a point of attachment of the damper to the structure. The damping coefficients of the damping elements are selected so that the dampers increase the effective loss factor of the structure. The passive dampers each have a damping mass which is supported such that the dampers experience an undamped natural frequency below the resonant frequencies and the frequency range of the structure.
摘要翻译：通过将多个离散的未调谐无源阻尼器应用于结构来阻尼结构振动。每个被动阻尼器包括阻尼元件和阻尼块，并且阻尼元件通常以与阻尼器与结构件的质量和连接点之间出现的相对速度成比例地提供阻尼。选择阻尼元件的阻尼系数，使阻尼器增加结构的有效损耗因子。无源阻尼器各自具有被支撑的阻尼质量，使得阻尼器在谐振频率和结构的频率范围之下经历无阻尼的固有频率。

4. 发明申请

US20110237467A1 NANOPARTICLE-DENSIFIED COMPLETION FLUIDS 审中-公开
标题翻译：纳米级透明液体
公开(公告)号：US20110237467A1
公开(公告)日：2011-09-29
申请号：US12731938
申请日：2010-03-25
申请人： H. Mitchell Cornette , Craig Gardner , Ben Bloys , Earl Coludrovich , Thomas G. Corbett , Henry Bergeron
发明人： H. Mitchell Cornette , Craig Gardner , Ben Bloys , Earl Coludrovich , Thomas G. Corbett , Henry Bergeron
IPC分类号： C09K8/68
CPC分类号： C09K8/03 , C09K8/32 , C09K8/52 , C09K8/70 , C09K2208/04 , C09K2208/10 , C09K2208/32
摘要： The present invention is directed to completion fluid compositions and methods of making same. Such completion fluids are unique in that they utilize nanoparticles as weighting (densification) agents that increase the specific gravity (or density) of the fluid into which they are dispersed. Depending on their properties, such nanoparticulate weighting agents can vastly broaden the types of base fluid used in the completion fluid, permitting the use of non-aqueous and even hydrocarbon base fluids. Additionally, such nanoparticle-densified completion fluids can provide reduced environmental risks, and the nanoparticle weighting agents used therein can be more easily recovered from the based fluids into which they are dispersed.
摘要翻译：本发明涉及完成流体组合物及其制备方法。这样的完井液是独特的，因为它们利用纳米颗粒作为增加其分散在其中的流体的比重（或密度）的加重（致密化）试剂。根据其性质，这种纳米颗粒增重剂可以极大地拓宽完井液中使用的基础流体的类型，允许使用非水基和甚至烃基流体。此外，这种纳米颗粒致密化的完井液可以提供降低的环境风险，并且其中使用的纳米颗粒加重剂可以更容易地从其分散在其中的基础流体中回收。

5. 发明申请

US20050090750A1 Determination of disease state using Raman Spectroscopy of tissue 有权
标题翻译：使用组织拉曼光谱法测定疾病状态
公开(公告)号：US20050090750A1
公开(公告)日：2005-04-28
申请号：US10742110
申请日：2003-12-19
申请人： Marwood Ediger , Craig Gardner , Edward Hull
发明人： Marwood Ediger , Craig Gardner , Edward Hull
IPC分类号： A61B5/00 , A61B5/103 , A61B6/00
CPC分类号： A61B5/061 , A61B5/0059 , A61B5/0064 , A61B5/0066 , A61B5/0068 , A61B5/0071 , A61B5/0075 , A61B5/412 , A61B5/441 , A61B5/443
摘要： A method of determining disease state in an individual. A portion of the tissue of the individual is illuminated with excitation light, then light emitted by the tissue due to Raman scattering of a chemical with the tissue responsive to the excitation light is detected. The detected light can be combined with a model relating Raman emission with disease state to determine a disease state of the individual. The invention can comprise single wavelength excitation light, scanning of excitation light (illuminating the tissue at a plurality of wavelengths), detection at a single wavelength, scanning of detection wavelengths (detecting emitted light at a plurality of wavelengths), and combinations thereof. The invention also can comprise correction techniques that reduce determination errors due to detection of light other than that from Raman emission of a chemical in the tissue. For example, the reflectance of the tissue can lead to errors if appropriate correction is not employed. The invention can also comprise a variety of models relating Raman emission to disease state, including a variety of methods for generating such models. Other biologic information can be used in combination with the Raman spectral properties to aid in the determination of disease state. The invention also comprises apparatuses suitable for carrying out the method, including appropriate light sources, detectors, and models (for example, implemented on computers) used to relate detected Raman emission and disease state.
摘要翻译：确定个体疾病状态的方法。用激发光照射个体的组织的一部分，然后检测由组织响应于激发光的化学物质的拉曼散射而由组织发射的光。检测到的光可以与将拉曼发射与疾病状态相关联的模型组合以确定个体的疾病状态。本发明可以包括单波长激发光，激发光的扫描（以多个波长照射组织），单个波长的检测，检测波长的扫描（检测多个波长的发射光）及其组合。本发明还可以包括校正技术，其减少由于检测除了组织中的化学物质的拉曼发射以外的光的测定误差。例如，如果不采用适当的校正，组织的反射率可能导致错误。本发明还可以包括将拉曼发射与疾病状态相关联的各种模型，包括用于产生这种模型的各种方法。其他生物信息可以与拉曼光谱性质结合使用，有助于确定疾病状态。本发明还包括适于执行该方法的装置，包括用于检测的拉曼发射和疾病状态的适当的光源，检测器和模型（例如，在计算机上实现的）。

6. 发明授权

US06240306B1 Method and apparatus for non-invasive blood analyte measurement with fluid compartment equilibration 失效
标题翻译：用流体隔室平衡测量非侵入性血液分析物的方法和装置
公开(公告)号：US06240306B1
公开(公告)日：2001-05-29
申请号：US09343800
申请日：1999-06-30
申请人： Mark Rohrscheib , Craig Gardner , Mark R. Robinson
发明人： Mark Rohrscheib , Craig Gardner , Mark R. Robinson
IPC分类号： A61B500
CPC分类号： A61B5/0059 , A61B5/14532 , A61B5/1455 , A61B5/1495 , A61B2562/146
摘要： A method and apparatus for non-invasively measuring the concentration of an analyte, particularly blood analyte in blood. The method utilizes spectrographic techniques in conjunction with equilibrating the concentration of the analyte between the vascular system fluid compartment of the test area and the other tissue fluid compartment. An improved optical interface between a sensor probe and a skin surface or tissue surface of the body containing the blood to be analyzed. Multiple readings during the equilibration period are taken and utilized to show the direction and rate of charge of concentration of the analyte in the blood which is useful in optimizing therapeutic response to the collected data.
摘要翻译：用于非侵入性地测量血液中分析物，特别是血液分析物浓度的方法和装置。该方法利用光谱技术结合平衡测试区域的血管系统流体隔室与另一组织液体隔室之间的分析物的浓度。传感器探针与包含要分析的血液的身体的皮肤表面或组织表面之间的改进的光学界面。在平衡期间进行多次读数并用于显示血液中分析物浓度的方向和速率，这有助于优化对收集的数据的治疗反应。

7. 发明申请

US20060167349A1 Apparatus for non-invasive determination of direction and rate of change of an analyte 失效
标题翻译：非侵入性测定分析物方向和变化率的装置
公开(公告)号：US20060167349A1
公开(公告)日：2006-07-27
申请号：US11328927
申请日：2006-01-10
申请人： Craig Gardner , Trent Ridder , William Gruner
发明人： Craig Gardner , Trent Ridder , William Gruner
IPC分类号： A61B5/00
CPC分类号： A61B5/1455 , A61B5/0059 , A61B5/0075 , A61B5/14532 , A61B5/1491 , A61B2560/0233 , A61B2562/146
摘要： The present invention relates generally to a non-invasive method and apparatus for measuring a fluid analyte, particularly relating to glucose or alcohol contained in blood or tissue, utilizing spectroscopic methods. More particularly, the method and apparatus incorporate means for detecting and quantifying changes in the concentration of specific analytes in tissue fluid. Also, the method and apparatus can be used to predict future levels of analyte concentration either in the tissue fluid or in blood in an adjacent vascular system.
摘要翻译：本发明一般涉及一种用于测量流体分析物，特别是与血液或组织中所含的葡萄糖或醇相关的非侵入性方法和装置，其使用光谱方法。更具体地，该方法和装置包括用于检测和量化组织液中特定分析物浓度变化的装置。此外，该方法和装置可以用于预测在相邻血管系统中的组织液或血液中的分析物浓度的未来水平。

8. 发明授权

US06983176B2 Optically similar reference samples and related methods for multivariate calibration models used in optical spectroscopy 失效
公开(公告)号：US06983176B2
公开(公告)日：2006-01-03
申请号：US09832608
申请日：2001-04-11
申请人： Craig Gardner , Michael J. Haass , Robert K. Rowe , Howland Jones , Steven T. Strohl , Matthew J. Novak , Russell E. Abbink , David Nuñez , William Gruner , Robert D. Johnson
发明人： Craig Gardner , Michael J. Haass , Robert K. Rowe , Howland Jones , Steven T. Strohl , Matthew J. Novak , Russell E. Abbink , David Nuñez , William Gruner , Robert D. Johnson
IPC分类号： A61B5/00
CPC分类号： G01N21/278 , A61B5/0075
摘要： Systems and methods for establishing and/or maintaining the prediction capability over time of a multivariate calibration model designed for quantitative optical spectroscopic measurement of attributes or analytes in bodily tissues, bodily fluids or other biological samples, which are particularly useful when the spectral absorbance of the attribute or analyte is small relative to the background. The present invention provides an optically similar reference sample to capture the characteristics of instrument and environmental variation and to reduce the effect of such variation on the measurement capability of the model. The optically similar reference is preferably stable over time and is designed such that its optical properties are sufficiently matched to the sample of interest that instrument and environmental variations are captured in the same manner in both the test sample of interest and the optically similar reference sample. The optically similar reference sample may include one or more physical components which are spectroscopically measured in a manner which closely mimics the spectroscopic measurement of the test sample of interest. Spectral similarity may also be achieved by using alternative components with spectral characteristics similar to the components contained in the test sample of interest.

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