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1. 发明公开

EP3110800A1 NOVEL COMPOUNDS HAVING ANTI-ALLODYNIC AND ANTIHYPERALGESIC ACTIVITY 审中-公开
标题翻译：抗坏血酸乙酯抗生素在抗生素治疗中的应用
公开(公告)号：EP3110800A1
公开(公告)日：2017-01-04
申请号：EP14718743.9
申请日：2014-02-27
申请人： Consorzio Interuniversitario Nazionale Per La Scienza E La Tecnologia Dei Materiali (INSTM) , Universita' Degli Studi di Firenze
发明人： NATIVI, Cristina , GHELARDINI, Carla , LA MARCA, Giancarlo
IPC分类号： C07D339/04 , C07D409/12 , A61K31/385 , A61P25/04
CPC分类号： C07D409/12 , A61K31/282 , A61K31/381 , A61K31/4025 , C07D339/04
摘要： The present invention relates to molecules of formula (I) where R1 = -SO3H, -PO3H, -PO2(OH)2, -OPO2H2, -NHSO3H, -S (N=H)Me, SH, SR o guanidyl; R = C1-4 alkyl, phenyl or 5 or 6 membered aromatic nitrogen heterocycles; n = 1, 2, 3, 4 o 5; X = C=0, C(OH)H, C(OAIk)H, C=S, CH2; Alk = C1-6 alkyl linear, branched or cyclic, optionally hydroxylated or polyhydroxylated; their preparation and use as analgesics and in the treatment of pain induced by chemotherapies.
摘要翻译：本发明涉及其中R 1 = -SO 3 H，-PO 3 H，-PO 2（OH）2，-OPO 2 H 2，-NHSO 3 H，-S（N = H）Me，SH，SR o胍基的式（I） R = C 1-4烷基，苯基或5或6元芳族氮杂环; n = 1,2,3,4 o 5; X = C = O，C（OH）H，C（OAI k）H，C = S，CH 2; 烷基=直链，支链或环状的C 1-6烷基，任选羟基化或多羟基化; 它们的制备和用途作为止痛剂和治疗由化疗引起的疼痛。

2. 发明公开

EP3587358A1 FILTER FOR REMOVING HEAVY METALS WHICH ARE HARMFUL TO HUMAN HEALTH FROM AQUEOUS SOLUTIONS AND METHOD FOR OBTAINING THEREOF 有权转让
公开(公告)号：EP3587358A1
公开(公告)日：2020-01-01
申请号：EP19182546.2
申请日：2019-06-26
申请人： Consorzio Interuniversitario Nazionale Per La Scienza E La Tecnologia Dei Materiali , Università degli Studi di Brescia
发明人： ALESSANDRI, Ivano , VASSALINI, Irene
IPC分类号： C02F1/28 , B01D39/18 , B01J20/24 , C02F101/22
摘要： The present invention relates to a filter comprising a porous material for removing heavy metals which are harmful to human health from aqueous solutions and to a method for obtaining thereof.
This method provides for the use of organic acids extracted from waste plants which are suitable for food consumption or from expired drugs for the functionalization of pre-existing filters comprising a porous material.
In particular, the present invention relates to a filter for removing hexavalent chromium from aqueous solutions.

3. 发明公开

EP1843144A1 System and method for tagging a product, associated certification method and tagging product 审中-公开
标题翻译：系统与Verfahren zum Etikettierung von Produkten，zugeordnetes Beglaubigungsverfahren und Etikettierungsprodukt
公开(公告)号：EP1843144A1
公开(公告)日：2007-10-10
申请号：EP06425232.3
申请日：2006-04-04
申请人： Consorzio Interuniversitario Nazionale Per La Scienza E La Tecnologia Dei Materiali (INSTM)
发明人： Veronesi, Fabio , Cardinali, Gianluigi , Fatichenti, Fabrizio , Rellini, Paolo , Kenny, José Maria , Petrucci, Roberto , Manzo, Alberto
IPC分类号： G01N21/31
CPC分类号： G01N21/31 , G01N2021/3196
摘要： What is described is a tagging system which comprises a material adapted to be associated with a product, such as a commercial product, an article, or the like. This material includes a base polymer matrix, adapted to provide a spectrum of response to one or more predetermined incident electromagnetic radiations, and at least one additive substance incorporated into a predetermined marking zone of the material. This additive substance is adapted to cause a modification of at least one characteristic of the response spectrum of the base matrix. The system also comprises a reference instructive item, for providing information correlated with at least one characteristic of the said modified spectrum. The information provided by the reference item is compared with corresponding information obtained from a spectral analysis of the material associated with the product in a method of certification of the product.
Also described are a tagging method based on the aforesaid system, a method of certification of a product tagged in this way, and tagging products such as a package, a label, an article, a textile, a varnish, paint or ink, and an adhesive product or sealant.
摘要翻译：描述的是标签系统，其包括适于与产品相关联的材料，例如商业产品，物品等。该材料包括基础聚合物基质，其适于提供对一个或多个预定入射电磁辐射的响应谱，以及掺入材料的预定标记区域中的至少一种添加剂物质。该添加剂物质适于引起基础基质的响应谱的至少一种特性的修饰。该系统还包括用于提供与所述修改的频谱的至少一个特征相关的信息的参考指导项目。将参考项目提供的信息与在产品认证方法中与产品相关联的材料的光谱分析获得的相应信息进行比较。还描述了基于上述系统的标记方法，以这种方式标记的产品的认证方法，以及标记诸如包装，标签，制品，纺织品，清漆，油漆或油墨的产品，以及粘合剂产品或密封剂。

4. 发明公开

EP3496761A1 FUNCTIONALIZED HYALURONIC ACID 有权转让
公开(公告)号：EP3496761A1
公开(公告)日：2019-06-19
申请号：EP17761924.4
申请日：2017-08-07
申请人： Consorzio Interuniversitario Nazionale Per La Scienza E La Tecnologia Dei Materiali , Universita' Degli Studi di Firenze , Università degli Studi di Siena
发明人： MAGNANI, Agnese , NATIVI, Cristina , LEONE, Gemma , LAMPONI, Stefania , CONSUMI, Marco , FRAGAI, Marco , BALDONESCHI, Veronica , RICHICHI, Barbara , FRANCESCONI, Oscar
IPC分类号： A61K47/61 , A61P27/04 , A61P19/02
摘要： The present invention describes the functionalization of sodium hyaluronate in a homogeneous phase with small molecules with proven inhibitory activity against membrane metalloproteins involved in the dry eye disease (MMP-2, MMP-9), in inflammatory processes at an osteoarticular level (MMP-12 and MMP-13) and in the formation of wrinkles (MMP-1 ). The hyaluronic acid derivative thus obtained (MMP- HA inhibitor) is useful for the medical treatment of dry eye and of inflammatory processes at the osteoarticular level, but also for the cosmetic treatment of skin blemishes due to aging processes.

5. 发明公开

EP2521731A1 COMPOUNDS WITH BOTH ANALGESIC AND ANTI-HYPERALGESIC EFFICACY 有权
标题翻译：具有镇痛和抗痛觉过敏作用CONNECTIONS
公开(公告)号：EP2521731A1
公开(公告)日：2012-11-14
申请号：EP11705998.0
申请日：2011-01-04
申请人： Consorzio Interuniversitario Nazionale Per La Scienza E La Tecnologia Dei Materiali (INSTM) , Nativi, Cristina , Ghelardini, Carla , La Marca, Giancarlo , Dragoni, Elisa
发明人： Consorzio Interuniversitario Nazionale Per La Scienza E La Tecnologia Dei Materiali (INSTM) , Nativi, Cristina , Ghelardini, Carla , La Marca, Giancarlo , Dragoni, Elisa
IPC分类号： C07K5/02 , A61K31/198
CPC分类号： C07D409/12
摘要： The present invention relates to molecules of formula (I), deriving from lipoic acid and camosine, their preparation and use as analgesics.

6. 发明公开

EP1378526A1 Partially fluorinated acrylic copolymers and their use as coatings, in particular antifouling coatings 审中-公开
标题翻译：部分氟化的丙烯酸酯共聚物和它们作为涂料，尤其是防污涂料使用
公开(公告)号：EP1378526A1
公开(公告)日：2004-01-07
申请号：EP03015084.1
申请日：2003-07-03
申请人： UNIVERSITA DEGLI STUDI DI GENOVA , Consorzio Interuniversitario Nazionale Per La Scienza E La Tecnologia Dei Materiali (INSTM)
发明人： Casazza, Elena , Piacenti, Franco , Russo, Saverio
IPC分类号： C08F8/18 , C09D5/16
CPC分类号： C08F220/24 , C08F8/18 , C08F214/186 , C08F220/18 , C08F265/04 , C08F283/006 , C08F290/00 , C08L51/003 , C09D5/1668 , C09D133/16 , C09D151/003 , C08F20/00 , C08L2666/02
摘要： Novel, partially fluorinated acrylic copolymers of formula:
wherein W is -CH 3 or -H, W 1 is -CH 3 or -H, m is an integer between 10 and 2000, n is an integer between 1 and 100, q is an integer between 0 (zero) and 17, t is 0 (zero) or 1, r is 0 (zero) or 1, p is 0 (zero) or 1, s is 0 (zero) or 1, T is an organic spacer constituted by an aliphatic hydrocarbon chain with from 1 to 6 carbon atoms and/or by a cycloaliphatic and/or aromatic structure, X is an ester, urethane, or amido group, L is an organic spacer constituted by an aliphatic hydrocarbon chain with from 1 to 6 carbon atoms and/or by a cycloaliphatic and/or aromatic structure, Y is an ester, urethane, or amido group, Rf is a perfluoroalkyl radical with from 1 to 7 carbon atoms or a perfluoropolyether radical formed by -CF 2 -O- and/or -CF 2 -CF 2 -O-, and/or -CF(CF 3 )-CF 2 -O- units, as well as a terminal halogen or hydrogen atom, are described.
摘要翻译：新颖的式部分氟化的丙烯酸类共聚物： worin W是-CH 3或-H，W <1>是-CH 3或-H，m为10和2000之间的整数，n是1和100之间的整数， q是0（零）和17之间的整数，t为0（零）或1，r是0（零）或1，p是0（零）或1，s为0（零）或1，T是的有机间隔在脂族烃链具有1至6个碳原子和/或由脂环族和/或芳族结构由通过，X为酯，氨基甲酸酯或酰胺基，L是通过在脂族烃链构成的有机间隔具有1至6个碳原子和/或由脂环族和/或芳族结构，Y是酯，氨基甲酸乙酯，或酰氨基，R f是用基团1至7个碳原子或全氟聚醚基团由-CF 2形成的全氟烷基 -O-和/或-CF 2 CF 2 O-，和/或-CF（CF 3）-CF 2 O单元，以及一个末端卤素或氢原子，被描述。

7. 发明授权

EP2521731B1 COMPOUNDS WITH BOTH ANALGESIC AND ANTI-HYPERALGESIC EFFICACY 有权
标题翻译：具有镇痛和抗痛觉过敏作用CONNECTIONS
公开(公告)号：EP2521731B1
公开(公告)日：2014-04-02
申请号：EP11705998.0
申请日：2011-01-04
申请人： Consorzio Interuniversitario Nazionale Per La Scienza E La Tecnologia Dei Materiali (INSTM) , Nativi, Cristina , Ghelardini, Carla , La Marca, Giancarlo , Dragoni, Elisa
发明人： NATIVI, Cristina , GHELARDINI, Carla , LA MARCA, Giancarlo , DRAGONI, Elisa
IPC分类号： C07K5/02 , A61K31/198
CPC分类号： C07D409/12

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