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1. 发明授权

US08597925B2 Homogeneously-structured nano-catalyst/enzyme composite electrode, fabricating method and application of the same 有权
标题翻译：均相结构的纳米催化剂/酶复合电极，其制备方法和应用
公开(公告)号：US08597925B2
公开(公告)日：2013-12-03
申请号：US12887768
申请日：2010-09-22
申请人： Bing-Joe Hwang , Min-Hsin Yeh , Shih-Hong Chang , Chung-Chiun Liu , Chao-Shan Chou
发明人： Bing-Joe Hwang , Min-Hsin Yeh , Shih-Hong Chang , Chung-Chiun Liu , Chao-Shan Chou
IPC分类号： C12N9/00 , C07K14/00
CPC分类号： C25D15/02 , A61B5/14532
摘要： A homogeneously-structured catalyst/enzyme composite structure formed by electrophoresis deposition (EPD) method. Catalyst and enzyme are simultaneously deposited onto the electrode surface by the EPD method, so as to form a film of catalyst/enzyme composite thereon. The film of catalyst/enzyme composite includes enzyme for catalyzing the biochemical reaction, and catalyst for increasing the rate of the electrochemical reaction, which are homogeneously mixed and forms a stable and three-dimensional structure. Also, this homogeneously-structured catalyst/enzyme composite is applicable as a working electrode of the bioreceptor in a mini-biosensor.
摘要翻译：通过电泳沉积（EPD）法形成均匀结构的催化剂/酶复合结构。催化剂和酶通过EPD方法同时沉积在电极表面上，从而在其上形成催化剂/酶复合膜。催化剂/酶复合膜包括用于催化生化反应的酶和用于提高电化学反应速率的催化剂，其均匀混合并形成稳定的三维结构。此外，该均匀结构的催化剂/酶复合物也可用作微生物传感器中生物受体的工作电极。

2. 发明申请

US20110155576A1 HOMOGENEOUSLY-STRUCTURED NANO-CATALYST/ENZYME COMPOSITE ELECTRODE, FABRICATING METHOD AND APPLICATION OF THE SAME 有权
标题翻译：均质结构的纳米催化剂/酶复合电极，制备方法及其应用
公开(公告)号：US20110155576A1
公开(公告)日：2011-06-30
申请号：US12887768
申请日：2010-09-22
申请人： Bing-Joe Hwang , Min-Hsin Yeh , Shih-Hong Chang , Chung-Chiun Liu , Chao-Shan Chou
发明人： Bing-Joe Hwang , Min-Hsin Yeh , Shih-Hong Chang , Chung-Chiun Liu , Chao-Shan Chou
IPC分类号： G01N27/327 , C25D15/00
CPC分类号： C25D15/02 , A61B5/14532
摘要： A homogeneously-structured catalyst/enzyme composite structure formed by electrophoresis deposition (EPD) method. Catalyst and enzyme are simultaneously deposited onto the electrode surface by the EPD method, so as to form a film of catalyst/enzyme composite thereon. The film of catalyst/enzyme composite includes enzyme for catalyzing the biochemical reaction, and catalyst for increasing the rate of the electrochemical reaction, which are homogeneously mixed and forms a stable and three-dimensional structure. Also, this homogeneously-structured catalyst/enzyme composite is applicable as a working electrode of the bioreceptor in a mini-biosensor.
摘要翻译：通过电泳沉积（EPD）法形成均匀结构的催化剂/酶复合结构。催化剂和酶通过EPD方法同时沉积在电极表面上，从而在其上形成催化剂/酶复合膜。催化剂/酶复合膜包括用于催化生化反应的酶和用于提高电化学反应速率的催化剂，其均匀混合并形成稳定的三维结构。此外，该均匀结构的催化剂/酶复合物也可用作微生物传感器中生物受体的工作电极。

3. 发明授权

US07232545B2 Sensor for determining concentration of fluid sterilant 有权
标题翻译：用于确定流体灭菌剂浓度的传感器
公开(公告)号：US07232545B2
公开(公告)日：2007-06-19
申请号：US10663593
申请日：2003-09-16
申请人： Michael A. Centanni , Chung-Chiun Liu , Dong Zhao , Jinsong Yu
发明人： Michael A. Centanni , Chung-Chiun Liu , Dong Zhao , Jinsong Yu
IPC分类号： G01N29/02
CPC分类号： A61L2/208 , A61L2/28 , A61L2202/14 , G01N29/036 , G01N2291/0256 , Y10T436/206664
摘要： A sensor for detecting hydrogen peroxide, comprising an element exhibiting piezoelectric properties having a metal-oxide-containing coating, the metal-oxide having a divalent or tetravalent state.
摘要翻译：一种用于检测过氧化氢的传感器，包括具有含金属氧化物的涂层的压电性能的元素，所述金属氧化物具有二价或四价态。

4. 发明申请

US20050063882A1 Sensor for determining concentration of fluid sterilant 有权
标题翻译：用于确定流体灭菌剂浓度的传感器
公开(公告)号：US20050063882A1
公开(公告)日：2005-03-24
申请号：US10663593
申请日：2003-09-16
申请人： Michael Centanni , Chung-Chiun Liu , Dong Zhao , Jinsong Yu
发明人： Michael Centanni , Chung-Chiun Liu , Dong Zhao , Jinsong Yu
IPC分类号： A61L2/20 , G01N27/00 , A61L2/00 , A61L9/00
CPC分类号： A61L2/208 , A61L2/28 , A61L2202/14 , G01N29/036 , G01N2291/0256 , Y10T436/206664
摘要： A sensor for detecting hydrogen peroxide, comprising an element exhibiting piezoelectric properties having a metal-oxide-containing coating, the metal-oxide having a divalent or tetravalent state.
摘要翻译：一种用于检测过氧化氢的传感器，包括具有含金属氧化物的涂层的压电性能的元素，所述金属氧化物具有二价或四价态。

5. 发明授权

US06387238B1 Electrolytic synthesis of peracetic acid 失效
标题翻译：过乙酸的电解合成
公开(公告)号：US06387238B1
公开(公告)日：2002-05-14
申请号：US09630934
申请日：2000-08-02
申请人： Tom L. Merk , Paul S. Malchesky , Chung-Chiun Liu
发明人： Tom L. Merk , Paul S. Malchesky , Chung-Chiun Liu
IPC分类号： C25B300
CPC分类号： A61L2/186 , A01N37/16 , A61L2/035 , A61L2/18 , A61L2202/21 , A61L2202/24 , C02F1/46109 , C02F1/4672 , C02F1/722 , C02F2001/46133 , C02F2001/46157 , C02F2201/46115 , C02F2303/04 , C07B2200/03 , C07C407/00 , C25B1/30 , C07C409/24
摘要： An electrolysis unit (10, 210, 310) has an anode (16, 216,316) and a gas diffusion cathode (18, 218, 318). Air is fed to the cathode (18, 218) to generate peroxide species, such as hydrogen peroxide, peroxide ions, or peroxide radicals by electrolysis of oxygenated water. A peracetic acid precursor, such as acetyl salicylic acid, reacts with the peroxide to form peracetic acid. An ion selective barrier (20, 220) optionally separates the unit into two chambers, an anodic chamber (12, 212) and a cathodic chamber (14, 214). By selecting either a proton permeable membrane or an anion exchange membrane for the barrier, the peracetic acid may be formed in either an alkaline electrolyte in the cathodic chamber or in an acid electrolyte in the anode chamber, respectively.
摘要翻译：电解单元（10,210,310）具有阳极（16,216,316）和气体扩散阴极（18,218,318）。通过电解含氧水将空气送入阴极（18,218）以产生过氧化物物质，例如过氧化氢，过氧化物离子或过氧化物自由基。过乙酸前体如乙酰水杨酸与过氧化物反应形成过乙酸。离子选择性屏障（20,220）可选地将该单元分离成两个室，阳极室（12,212）和阴极室（14,214）。通过选择用于阻挡层的质子渗透膜或阴离子交换膜，过乙酸可以分别在阴极室中的碱性电解质中或在阳极室中的酸性电解质中形成。

6. 发明授权

US4340448A Potentiometric detection of hydrogen peroxide and apparatus therefor 失效
标题翻译：过氧化氢的电位检测及其设备
公开(公告)号：US4340448A
公开(公告)日：1982-07-20
申请号：US937365
申请日：1978-08-28
申请人： Julian G. Schiller , Lemuel B. Wingard, Jr. , Chung-Chiun Liu
发明人： Julian G. Schiller , Lemuel B. Wingard, Jr. , Chung-Chiun Liu
IPC分类号： C12Q1/00 , C12Q1/54 , G01N27/416 , C12Q1/26 , C12Q1/30 , G01N27/46
CPC分类号： C12Q1/54 , C12Q1/005 , G01N27/3271 , Y10S435/817
摘要： A method for potentiometric detection of hydrogen peroxide including providing an electrolytic cell having a working electrode and a reference electrode. The working electrode is composed of a hydrogen peroxide sensitive material and also is employed as a support for an oxidase enzyme. Introducing a hydrogen peroxide releasing substance into the cell and releasing the hydrogen peroxide by effecting interaction with the enzyme. Developing in said cell an electrical potential which is a function of the concentration of the hydrogen peroxide and measuring the electrical potential of the cell. The method may be employed as a quantitative glucose detector by employing as the enzyme or enzymes glucose oxidase with or without catalase.Apparatus for potentiometric determination of hydrogen peroxide includes a cell containing an electrolyte, a working electrode and a reference electrode. An electrometer is operatively associated with the electrodes. The working electrode is composed of a material which will create an electrical potential when it interacts with hydrogen peroxide. At least one oxidase enzyme is immobilized on the working electrode.
摘要翻译：一种用于电位检测过氧化氢的方法，包括提供具有工作电极和参比电极的电解池。工作电极由过氧化氢敏感材料组成，也用作氧化酶的载体。引入过氧化氢释放物质进入细胞并通过与酶的相互作用释放过氧化氢。在所述电池中显影电位，其是过氧化氢浓度和测量电池电位的函数。该方法可以用作定量葡萄糖检测器，通过使用具有或不具有过氧化氢酶的酶或酶葡萄糖氧化酶。用于电位测定过氧化氢的装置包括含有电解质，工作电极和参考电极的电池。静电计可操作地与电极相关联。工作电极由与过氧化氢相互作用时产生电位的材料组成。至少一种氧化酶固定在工作电极上。

7. 发明授权

US06623620B2 Method for detecting or monitoring sulfur dioxide with an electrochemical sensor 失效
标题翻译：用电化学传感器检测或监测二氧化硫的方法
公开(公告)号：US06623620B2
公开(公告)日：2003-09-23
申请号：US09466865
申请日：1999-12-17
申请人： Ann Lai , Laurie A. Dudik , Chung-Chiun Liu
发明人： Ann Lai , Laurie A. Dudik , Chung-Chiun Liu
IPC分类号： G01N27407
CPC分类号： G01N27/4045 , G01N33/0042 , Y02A50/248
摘要： A thick film electrochemical micro-sensor device for detecting or monitoring sulfur dioxide, comprising a substrate to which is applied a working electrode, a counter electrode, a reference electrode, and optionally a heater and a temperature detector, wherein a portion of the electrodes is covered with an insulator, and a portion of the electrodes is covered with an electrolyte. The device is especially useful for detecting or monitoring sulfur dioxide in emission gases. A method of detecting or monitoring sulfur dioxide emissions using the electrochemical micro-sensor device includes contacting the emission gas with the sensor of the present invention, measuring the current output of the sensor, determining if the current output indicates the presence of sulfur dioxide, and generating a signal, that can be used to actuate a scrubber system when a pre-determined level of sulfur dioxide is detected.
摘要翻译：一种用于检测或监测二氧化硫的厚膜电化学微传感器装置，包括施加工作电极，对电极，参考电极以及任选的加热器和温度检测器的衬底，其中电极的一部分覆盖有绝缘体，并且一部分电极被电解质覆盖。该装置特别适用于检测或监测排放气体中的二氧化硫。使用电化学微量传感器装置检测或监测二氧化硫排放的方法包括使排放气体与本发明的传感器接触，测量传感器的电流输出，确定当前输出是否表示二氧化硫的存在，以及产生信号，当检测到预定量的二氧化硫时，该信号可用于致动洗涤器系统。

8. 发明授权

US6023961A Micro-viscosity sensor and lubrication analysis system employing the same 失效
标题翻译：微粘度传感器和使用其的润滑分析系统
公开(公告)号：US6023961A
公开(公告)日：2000-02-15
申请号：US54117
申请日：1998-04-02
申请人： Frederick M. Discenzo , Chung-Chiun Liu , Donald L. Feke , Laurie Ann Dudik
发明人： Frederick M. Discenzo , Chung-Chiun Liu , Donald L. Feke , Laurie Ann Dudik
IPC分类号： F16C19/52 , G01N11/16 , G01N29/02 , G01N33/28 , G01N33/30 , G01N9/00
CPC分类号： F16C19/52 , F16C41/008 , G01N11/16 , G01N29/022 , G01N33/2888 , G01N33/30 , F16N2250/30 , F16N2250/36 , F16N2260/18 , F16N2270/52 , F16N2270/54 , F16N2270/56 , G01N2291/0226 , G01N2291/0256 , G01N2291/02818 , G01N2291/106
摘要： A micro-viscosity sensor for measuring the viscosity of a lubricant. The micro-viscosity sensor including at least one finger-like element or an array of finger-like elements vertically extending from the surface of a semiconductor base, the at least one finger-like element being oscillated at a desired frequency. The power required to oscillate the at least one-finger-like element is monitored because the power required is a function of the viscosity of the lubricant. The sensor also includes a temperature detector, wherein the thermal conductivity of the temperature detector varies in correspondence with the temperature of the lubricant. A first set of electrical contacts provides for electrical connection to the at least one finger-like element; and a second set of electrical contacts provides for electrical connection to the temperature detector. The viscosity of the lubricant is determined based on the temperature of the lubricant correlated with the power required to oscillate the at least one-finger like element at a particular frequency.
摘要翻译：用于测量润滑剂粘度的微粘度传感器。微粘度传感器包括至少一个手指状元件或从半导体基底的表面垂直延伸的指状元件的阵列，所述至少一个指状元件以期望的频率振荡。监测振荡至少一指指状元件所需的功率，因为所需的功率是润滑剂粘度的函数。传感器还包括温度检测器，其中温度检测器的热导率根据润滑剂的温度而变化。第一组电触点提供与至少一个手指状元件的电连接; 并且第二组电触点提供与温度检测器的电连接。润滑剂的粘度基于与以特定频率振荡至少一个手指状元件所需的功率相关的润滑剂的温度来确定。

9. 发明授权

US4571292A Apparatus for electrochemical measurements 失效
标题翻译：电化学测量仪器
公开(公告)号：US4571292A
公开(公告)日：1986-02-18
申请号：US407566
申请日：1982-08-12
申请人： Chung-Chiun Liu , Vasilios A. Karagounis
发明人： Chung-Chiun Liu , Vasilios A. Karagounis
IPC分类号： G01N27/49 , G01N27/46
CPC分类号： G01N27/404
摘要： A sensor for an electrochemically active species, such as oxygen, uses more than two electrodes, namely, at least a working electrode, counter electrode and reference electrode. The sensor preferably is substantially planar, is made using thick film or thin film technique and accordingly may be very small. With the sensor in an electrolyte balanced reverse reactions occur, respectively, at the working and counter electrodes while no reaction occurs at the reference electrode, which is maintained in equilibrium with the electrolyte, and voltage between the working the reference electrodes is maintained constant. Current flow between the working and counter electrodes, then, provides an accurate, stable representation of species concentration.
摘要翻译：用于电化学活性物质如氧的传感器使用两个以上的电极，即至少一个工作电极，对电极和参比电极。传感器优选地基本上是平面的，使用厚膜或薄膜技术制造，因此可能非常小。在传感器处于电解质时，分别在工作电极和对电极处发生平衡的反向反应，而在与电解质保持平衡的参考电极上没有发生反应，并且工作的参考电极之间的电压保持恒定。然后，工作电极和对电极之间的电流提供了物质浓度的准确，稳定的表示。

10. 发明授权

US10444180B1 Polymer electrolyte-based sensors 有权
公开(公告)号：US10444180B1
公开(公告)日：2019-10-15
申请号：US13552760
申请日：2012-07-19
申请人： Gary W Hunter , Jennifer C Xu , Chung-Chiun Liu
发明人： Gary W Hunter , Jennifer C Xu , Chung-Chiun Liu
IPC分类号： G01N27/406 , G01N27/407
摘要： A polymer electrolyte-based sensor is disclosed. The sensor includes a conductive polymer electrolyte film including water-retaining components. The water-retaining components facilitate operational conductivity of the conductive polymer electrolyte film in lower humidity environments than would be possible without the water-retaining components.

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