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1. 发明申请

WO2007129087A1 PLASMID CURING 审中-公开
标题翻译：等离子体固化
公开(公告)号：WO2007129087A1
公开(公告)日：2007-11-15
申请号：PCT/GB2007/001682
申请日：2007-05-09
申请人： THE UNIVERSITY OF BIRMINGHAM , THOMAS, Christopher, Morton
发明人： THOMAS, Christopher, Morton
IPC分类号： C12N15/09
CPC分类号： C12N15/63
摘要： The present invention relates to plasmid curing, and particularly to efficient and stress-free methods for displacing resident or endogenous plasmids from a host cell, such as a bacterium. The invention extends to method of displacing a plasmid comprising a post-segregational killing system from a host cell, the method comprising introducing a recombinant nucleic acid molecule into a host cell harbouring a plasmid comprising a post-segregational killing (PSK) system, characterised in that the recombinant nucleic acid molecule is adapted to neutralise the toxic effects of the plasmid' s post-segregational killing system, and wherein the nucleic acid molecule is also adapted to outcompete or inhibit replication of the plasmid. The invention further extends to recombinant nucleic acid molecules that can be used in this method, as well as further uses of the methods and nucleic acid molecules of the invention.
摘要翻译：本发明涉及质粒固化，特别涉及用于从宿主细胞（例如细菌）中置换居民或内源性质粒的有效和无应力的方法。本发明延伸到将包含后隔离杀伤系统的质粒从宿主细胞置换的方法，所述方法包括将重组核酸分子引入宿主细胞中，所述质粒包含分离后杀伤（PSK）系统，其特征在于所述重组核酸分子适于中和所述质粒的分离后杀灭系统的毒性作用，并且其中所述核酸分子也适于超出或抑制所述质粒的复制。本发明进一步延伸到可用于该方法的重组核酸分子，以及本发明的方法和核酸分子的进一步使用。

2. 发明申请

WO2013082488A2 OPTICAL COATING METHOD, APPARATUS AND PRODUCT 审中-公开
标题翻译：光学涂层方法，设备和产品
公开(公告)号：WO2013082488A2
公开(公告)日：2013-06-06
申请号：PCT/US2012/067383
申请日：2012-11-30
申请人： CORNING INCORPORATED , LEE, Christopher Morton , LU, Xiao-Feng , OUYANG, Michael Xu , ZHANG, Junhong
发明人： LEE, Christopher Morton , LU, Xiao-Feng , OUYANG, Michael Xu , ZHANG, Junhong
IPC分类号： G02B1/11 , B05D5/06
CPC分类号： G02B1/11 , B05C13/00 , B05D5/061 , C03C17/002 , C03C17/42 , C03C2217/73 , C03C2217/734 , C03C2217/76 , C03C2217/78 , C03C2218/151 , C03C2218/32 , C23C14/044 , C23C14/12 , C23C14/24 , C23C14/505 , C23C14/56 , G02B1/115
摘要： This disclosure is directed to an improved process for making glass articles having optical coating and easy-to clean coating thereon, an apparatus for the process and a product made using the process. In particular, the disclosure is directed to a process in which the application of the optical coating and the easy-to-clean coating can be sequentially applied using a single apparatus. Using the combination of the coating apparatus and the substrate carrier described herein results in a glass article having both optical and easy-to-clean coating that have improved scratch resistance durability and optical performance, and in addition the resulting articles are "shadow free."
摘要翻译：本发明涉及用于制造其上具有光学涂层和易清洁涂层的玻璃制品的改进方法，用于该方法的设备和使用该方法制造的产品。具体而言，本公开涉及一种方法，其中可以使用单个装置依次施加光学涂层和易清洁涂层。使用本文所述的涂布设备和基材载体的组合导致具有光学且易于清洁的涂层的玻璃制品具有改进的耐刮擦耐久性和光学性能，此外所得制品是“无影的”。＆QUOT;

3. 发明申请

WO2009111390A1 METHODS OF FABRICATING ENHANCED TISSUE-ENGINEERED CARTILAGE 审中-公开
标题翻译：制备增强组织工程化纤维的方法
公开(公告)号：WO2009111390A1
公开(公告)日：2009-09-11
申请号：PCT/US2009/035712
申请日：2009-03-02
申请人： WILLIAM MARSH RICE UNIVERSITY , ATHANASIOU, Kyriacos, A. , ELDER, Benjamin, Daniel , HU, Jerry , NATOLI, Roman, M. , REVELL, Christopher, Morton
发明人： ATHANASIOU, Kyriacos, A. , ELDER, Benjamin, Daniel , HU, Jerry , NATOLI, Roman, M. , REVELL, Christopher, Morton
IPC分类号： A61F2/08
CPC分类号： A61L27/3852 , A61L27/3817 , A61L27/3895 , C12N5/0655 , C12N2501/70 , C12N2521/00 , C12N2533/76
摘要： Compositions and methods for fabricating a tissue-engineered cartilage construct comprising: providing a cell sample comprising a plurality of chondrocytes; culturing the cell sample to produce a tissue-engineered cartilage construct; and treating the tissue-engineered cartilage construct, wherein treating the tissue-engineered cartilage construct comprises the use of a biochemical reagent, a mechanical force, hydrostatic pressure, or any combination thereof.
摘要翻译：用于制备组织工程软骨构建体的组合物和方法，包括：提供包含多个软骨细胞的细胞样品; 培养细胞样品以产生组织工程化的软骨构建体; 以及治疗所述组织工程化软骨构建体，其中处理所述组织工程化软骨构建体包括使用生化试剂，机械力，静水压力或其任何组合。

4. 发明申请

WO2013082477A3 PROCESS FOR MAKING OF GLASS ARTICLES WITH OPTICAL AND EASY-TO-CLEAN COATINGS 审中-公开
标题翻译：用光学和易清洁涂层制作玻璃制品的方法
公开(公告)号：WO2013082477A3
公开(公告)日：2013-09-26
申请号：PCT/US2012067370
申请日：2012-11-30
申请人： CORNING INC , LEE CHRISTOPHER MORTON , LU XIAO-FENG , OUYANG MICHAEL XU , ZHANG JUNHONG
发明人： LEE CHRISTOPHER MORTON , LU XIAO-FENG , OUYANG MICHAEL XU , ZHANG JUNHONG
IPC分类号： C03C17/42 , C03C17/00
CPC分类号： C03C17/42 , C03C17/002 , C03C2217/734 , C03C2217/76 , C03C2217/78 , C03C2218/151 , C03C2218/152 , C03C2218/32 , G02B1/111 , G02B27/0006
摘要： The present disclosure is directed to a process in which both an optical coating, for example an AR coating, and an ETC coating can be applied to a glass substrate article, in sequential steps of the optical coating first and the ETC coating second, using substantially the same procedure without exposing the article to the atmosphere at any time during the application of the optical coating and ETC coating. After post-treating the article to create strong chemical bonding between the ETC coating and the optical coating deposited on the substrate, and cross-linking between ETC molecules, the article has an average water contact angle of at least 70° after 5,500 abrasion cycles using with #0 steel wool and 1 kg weight load on a 1 cm surface area.
摘要翻译：本公开涉及一种方法，其中光学涂层例如AR涂层和ETC涂层可以在第一次光学涂层和ETC涂层的顺序步骤中施加到玻璃基板制品上，使用基本上在使用光学涂层和ETC涂层期间的任何时间将物品暴露于大气中的相同程序。在后处理该物品以在ETC涂层和沉积在基底上的光学涂层之间产生强化学键合以及ETC分子之间的交联之后，该物品在5,500次磨擦循环之后具有至少70°的平均水接触角，使用在1厘米表面积上具有＃0钢丝绒和1公斤重量载荷。

5. 发明申请

WO2013082488A3 OPTICAL COATING METHOD, APPARATUS AND PRODUCT 审中-公开
标题翻译：光学涂层方法，装置和产品
公开(公告)号：WO2013082488A3
公开(公告)日：2013-08-22
申请号：PCT/US2012067383
申请日：2012-11-30
申请人： CORNING INC , LEE CHRISTOPHER MORTON , LU XIAO-FENG , OUYANG MICHAEL XU , ZHANG JUNHONG
发明人： LEE CHRISTOPHER MORTON , LU XIAO-FENG , OUYANG MICHAEL XU , ZHANG JUNHONG
IPC分类号： C03C17/00 , C03C17/42 , C23C14/24 , C23C14/50 , C23C14/54 , C23C16/458
CPC分类号： G02B1/11 , B05C13/00 , B05D5/061 , C03C17/002 , C03C17/42 , C03C2217/73 , C03C2217/734 , C03C2217/76 , C03C2217/78 , C03C2218/151 , C03C2218/32 , C23C14/044 , C23C14/12 , C23C14/24 , C23C14/505 , C23C14/56 , G02B1/115
摘要： This disclosure is directed to an improved process for making glass articles having optical coating and easy-to clean coating thereon, an apparatus for the process and a product made using the process. In particular, the disclosure is directed to a process in which the application of the optical coating and the easy-to-clean coating can be sequentially applied using a single apparatus. Using the combination of the coating apparatus and the substrate carrier described herein results in a glass article having both optical and easy-to-clean coating that have improved scratch resistance durability and optical performance, and in addition the resulting articles are "shadow free."
摘要翻译：本公开涉及一种用于制造具有光学涂层并且易于清洁涂层的玻璃制品的改进方法，用于该方法的装置和使用该方法制造的产品。特别地，本公开涉及一种可以使用单个装置顺序地施加光学涂层和易于清洁的涂层的方法。使用本文所述的涂布装置和基底载体的组合，可以得到具有改善的耐刮擦性耐久性和光学性能的光学和易于清洁的涂层的玻璃制品，并且所得到的制品“无影像”。

6. 发明申请

WO2013082477A2 PROCESS FOR MAKING OF GLASS ARTICLES WITH OPTICAL AND EASY-TO-CLEAN COATINGS 审中-公开
标题翻译：用光学和易清洁涂层制作玻璃制品的方法
公开(公告)号：WO2013082477A2
公开(公告)日：2013-06-06
申请号：PCT/US2012/067370
申请日：2012-11-30
申请人： CORNING INCORPORATED , LEE, Christopher Morton , LU, Xiao-feng , OUYANG, Michael Xu , ZHANG, Junhong
发明人： LEE, Christopher Morton , LU, Xiao-feng , OUYANG, Michael Xu , ZHANG, Junhong
IPC分类号： G02B1/11 , B05D5/06
CPC分类号： G02B1/11 , C03C17/002 , C03C17/42 , C03C2217/734 , C03C2217/76 , C03C2217/78 , C03C2218/151 , C03C2218/152 , C03C2218/32 , G02B1/111 , G02B1/18 , G02B27/0006
摘要： The present disclosure is directed to a process in which both an optical coating, for example, and AR coating, and an ETC coating can be applied to a glass substrate article, in sequential steps of the optical coating first and the ETC coating second, using substantially the same procedure without exposing the article to the atmosphere at any time during the application of the optical coating and ETC coating. After post-treating the article to create strong chemical bonding between the ETC coating and the optical coating deposited on the substrate, and cross-linking between ETC molecules, the article has an average water contact angle of at least 70° after 5,500 abrasion cycles using with #0 steel wool and 1kg weight load on a 1cm2 surface area.
摘要翻译：本公开涉及一种方法，其中光学涂层例如AR涂层和ETC涂层可以在光学涂层第一和ETC涂层的顺序步骤中施加到玻璃基板制品上，其次使用在使用光学涂层和ETC涂层期间的任何时间将制品暴露于大气中的程序基本相同。在后处理该物品以在ETC涂层和沉积在基底上的光学涂层之间产生强化学键合以及ETC分子之间的交联之后，该物品在5,500次磨擦循环之后具有至少70°的平均水接触角，使用在1cm2表面积上配备＃0钢丝绒和1kg重量载荷。

7. 发明申请

WO2014055134A1 OPTICAL COATING METHOD, APPARTUS AND PRODUCT 审中-公开
标题翻译：光学涂层方法，APPARTUS和产品
公开(公告)号：WO2014055134A1
公开(公告)日：2014-04-10
申请号：PCT/US2013/043415
申请日：2013-05-30
申请人： CORNING INCORPORATED , LEE, Christopher Morton , LU, Xiao-Feng , OUYANG, Michael Xu , ZHANG, Junhong
发明人： LEE, Christopher Morton , LU, Xiao-Feng , OUYANG, Michael Xu , ZHANG, Junhong
IPC分类号： C23C14/50 , C23C16/458
CPC分类号： C23C14/505 , C23C14/547 , C23C16/4581 , C23C16/4584 , C23C16/4585 , C23C16/52
摘要： This disclosure is directed to an improved process for making glass articles having optical coating and easy-to clean coating thereon, an apparatus for the process and a product made using the process. In particular, the disclosure is directed to a process in which the application of the optical coating and the easy-to-clean coating can be sequentially applied using a single apparatus. Using the combination of the coating apparatus and the substrate carrier described herein results in a glass article having both optical and easy-to-clean coating that have improved scratch resistance durability and optical performance, and in addition the resulting articles are "shadow free."
摘要翻译：本公开涉及一种用于制造具有光学涂层并且易于清洁涂层的玻璃制品的改进方法，用于该方法的装置和使用该方法制造的产品。特别地，本公开涉及一种可以使用单个装置顺序地施加光学涂层和易于清洁的涂层的方法。使用本文所述的涂布装置和基底载体的组合，可以得到具有改善的耐刮擦性耐久性和光学性能的光学和易于清洁的涂层的玻璃制品，并且所得到的制品“无影像”。

8. 发明申请

US20050013199A1 Tide clock utilizing GPS data 审中-公开
标题翻译：潮汐时钟利用GPS数据
公开(公告)号：US20050013199A1
公开(公告)日：2005-01-20
申请号：US10763342
申请日：2004-01-23
申请人： Daniel Danks , Mary Danks , Richard Danks , Christopher Morton , David Whipple , Kathleen Danks
发明人： Daniel Danks , Mary Danks , Richard Danks , Christopher Morton , David Whipple , Kathleen Danks
IPC分类号： G04G9/00 , G04B19/26
CPC分类号： G04G9/0076
摘要： A tide clock that utilizes global positioning system data to calculate tidal events. The tide clock includes a receiver that receives global positioning data describing the clock's position, and a memory having algorithms selectable to calculate the time of a tidal event for multiple locations.
摘要翻译：潮汐时钟，利用全球定位系统数据来计算潮汐事件。潮汐时钟包括接收器，其接收描述时钟位置的全球定位数据，以及存储器，其具有可选择的算法以计算多个位置的潮汐事件的时间。

9. 发明申请

US20110053262A1 METHODS OF FABRICATING ENHANCED TISSUE-ENGINEERED CARTILAGE 审中-公开
标题翻译：制备增强组织工程化纤维的方法
公开(公告)号：US20110053262A1
公开(公告)日：2011-03-03
申请号：US12874803
申请日：2010-09-02
申请人： Kyriacos A. Athanasiou , Benjamin Daniel Elder , Jerry Hu , Roman M. Natoli , Christopher Morton Revell
发明人： Kyriacos A. Athanasiou , Benjamin Daniel Elder , Jerry Hu , Roman M. Natoli , Christopher Morton Revell
IPC分类号： C12N5/00 , C12N5/02
CPC分类号： A61L27/3852 , A61L27/3817 , A61L27/3895 , C12N5/0655 , C12N2501/70 , C12N2521/00 , C12N2533/76
摘要： Compositions and methods for fabricating a tissue-engineered cartilage construct comprising: providing a cell sample comprising a plurality of chondrocytes; culturing the cell sample to produce a tissue-engineered cartilage construct; and treating the tissue-engineered cartilage construct, wherein treating the tissue-engineered cartilage construct comprises the use of a biochemical reagent, a mechanical force, hydrostatic pressure, or any combination thereof.
摘要翻译：用于制备组织工程软骨构建体的组合物和方法，包括：提供包含多个软骨细胞的细胞样品; 培养细胞样品以产生组织工程化的软骨构建体; 以及治疗所述组织工程化软骨构建体，其中处理所述组织工程化软骨构建体包括使用生化试剂，机械力，静水压力或其任何组合。

10. 发明申请

US20050151767A1 Methods and apparatus for an automatic fluid ejector alignment and performance system 有权
标题翻译：自动流体喷射器对准和性能系统的方法和装置
公开(公告)号：US20050151767A1
公开(公告)日：2005-07-14
申请号：US10752717
申请日：2004-01-08
申请人： Andrew Yeh , Roger Markham , Lesley Dudek , Eduardo Freire , Gary Kneezel , Christopher Morton
发明人： Andrew Yeh , Roger Markham , Lesley Dudek , Eduardo Freire , Gary Kneezel , Christopher Morton
IPC分类号： B41J2/01 , B41J2/165 , B41J29/38 , B41J29/393
CPC分类号： B41J2/2142 , B41J29/393
摘要： Methods and apparatus provide for automatic fluid ejector alignment and performance evaluation and modification in one or multiple planes. A fluid ejector fires a drop through a drop detection module. A signal indicating drop presence or absence is sent to a computer. The computer analyzes the data, and makes a compensation determination of a preferred method of using the fluid ejector. The compensation determination may include electronically modifying the image data to be printed, physically manipulating the fluid ejector, completely skipping the fluid ejector during printing operations, or in some other way modifying the fluid ejector or image data such that apparent printed image error due to fluid ejector alignment or performance error is reduced.
摘要翻译：方法和装置提供了一个或多个平面中的自动流体喷射器对准和性能评估和修改。液体喷射器通过液滴检测模块触发液滴。指示下降存在或不存在的信号被发送到计算机。计算机分析数据，并对使用流体喷射器的优选方法进行补偿确定。补偿确定可以包括电子修改要打印的图像数据，物理地操纵流体喷射器，在打印操作期间完全跳过流体喷射器，或以某种其他方式修改流体喷射器或图像数据，使得由于流体而导致的明显的印刷图像误差喷射器对准或性能误差降低。

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