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1. 发明申请

US20090232864A1 METHOD FOR APPLYING A BIOACTIVE, TISSUE-COMPATIBLE LAYER ONTO SHAPED ARTICLES AND THE USE OF SUCH SHAPED ARTICLES 审中-公开
标题翻译：将生物活性，组织相容性层应用于形状文章的方法和使用这种形状的文章
公开(公告)号：US20090232864A1
公开(公告)日：2009-09-17
申请号：US12306404
申请日：2007-05-15
申请人： Christoph Schultheiss
发明人： Christoph Schultheiss
IPC分类号： A61K9/00 , C23C14/34 , A61P43/00 , A61B5/07
CPC分类号： A61L27/306
摘要： A method for applying a bioactive, tissue-compatible layer onto a shaped article includes providing, as a target material, a bioactive glass ceramic having a S53P4 composition, cleaning a shaped article and activating a surface of the shaped article with ions. The Shaped article is exposed to a bioactive glass ceramic beam pulse ablated by a pulsed electron-beam ablation of the bioactive glass ceramic target material so as to deposit a bioactive glass ceramic layer having a thickness ranging from 1 μm to 10 μm on the surface of the shaped article. A respective pulse frequency of the at least one of: 1) an electron pulse of the pulse electron beam abalation, and 2) the bioactive glass ceramic beam pulse, is controlled. Prior to an implantation, so as to avoid an initial cytotoxicity, at least one of the following is performed: a) an exposure of the article at least the times to 24-hour contact with at least one of a culture medium (SBL), a de-mineralized water, and a 0.9% NaCl electrolyte, and b) a wet-vapor sterilization of the article.
摘要翻译：将生物活性的组织相容层施加到成形制品上的方法包括提供具有S53P4组合物的生物活性玻璃陶瓷作为靶材料，用离子清洁成型制品和活化成形制品的表面。将成形制品暴露于通过生物活性玻璃陶瓷靶材料的脉冲电子束烧蚀消融的生物活性玻璃陶瓷束脉冲，以沉积厚度范围为1〜10μm的生物活性玻璃陶瓷层，表面为成型制品。以下至少一个的相应脉冲频率：1）脉冲电子束衰减的电子脉冲和2）生物活性玻璃陶瓷束脉冲被控制。在植入之前，为了避免初始细胞毒性，进行以下至少一种：a）至少将制品暴露于与培养基（SBL），去矿化水和0.9％NaCl电解质，以及b）制品的湿蒸气灭菌。

2. 发明申请

US20080279995A1 Process for the More Effective and Gentle Release of Quality-Enhancing Constituents From Grapes, the Young Wine Obtained in the Process and the Wine Produced Therefrom, as Well as a Device for Carrying Out the Electroporation 审中-公开
标题翻译：更加有效和温和地释放葡萄品质提升成分，过程中获得的年轻葡萄酒和生产的葡萄酒，以及进行电穿孔的设备
公开(公告)号：US20080279995A1
公开(公告)日：2008-11-13
申请号：US10593694
申请日：2005-03-04
申请人： Christoph Schultheiss , Rolf Nuesch , Hanns-Gunther Mayer , Jurgen Sigler , Martin Kern
发明人： Christoph Schultheiss , Rolf Nuesch , Hanns-Gunther Mayer , Jurgen Sigler , Martin Kern
IPC分类号： C12G1/02 , A23N1/00 , C12M1/42
CPC分类号： C12G1/02 , C02F1/4608 , C02F2103/325
摘要： An improved and more gentle process for extracting useful substances from wine grapes is achieved by electroporation of the must produced from red and/or white grapes. The must is pumped or circulated before the pressing applied for must production through an installation or part of an installation and pulsed electric fields are applied therein to irreversibly rupture the biological cell walls of the grape skins. The device for carrying out must electroporation comprises a dielectric pipe, the flow duct for the must, in whose wall are arranged two mutually spaced electrodes to form a pulsed electric field between the electrodes. The must, which forms the electrolytic load of the device, has an electric resistance at least as high as the impedance of a high-voltage pulse generator connected to the device.
摘要翻译：从葡萄葡萄中提取有用物质的改进和更温和的方法是通过电穿孔从红葡萄和/或白葡萄产生的必需品实现的。必须在通过安装或部分安装施加必须生产的压制之前泵送或循环，并且施加脉冲电场以不可逆地破坏葡萄皮的生物细胞壁。用于进行的装置必须电穿孔包括介电管，用于必须的流动管道，其壁中布置有两个相互间隔的电极，以在电极之间形成脉冲电场。形成器件的电解负载的必须具有至少与连接到器件的高电压脉冲发生器的阻抗一样高的电阻。

3. 发明授权

US5978445A Spectrometer for X-radiation 失效
标题翻译： X射线光谱仪
公开(公告)号：US5978445A
公开(公告)日：1999-11-02
申请号：US666443
申请日：1997-03-19
申请人： Christoph Schultheiss , Waldemar Jakobi, deceased
发明人： Christoph Schultheiss , Waldemar Jakobi, deceased
IPC分类号： G21K1/06 , G01T1/36 , G21K1/00 , G21K1/02 , G21K3/00
CPC分类号： G21K1/025 , G01T1/36
摘要： The invention relates to a spectrometer for X-radiation, including a disk which is impervious to the radiation and which has a first and a second surface provided with a plurality of channels or bores measuring a maximum of 50 .mu.m. The bores are disposed in such a manner that they extend from the first to the second disk surface and their extensions point toward a common line or a common point, with the common line or common point being located opposite the second surface. Also provided is a device with the aid of which the arching of the disk can be altered in such a way that the distance of the common line or common point from the concave surface changes.
摘要翻译： PCT No.PCT / EP95 / 03775第 371日期1997年3月19日 102（e）1997年3月19日PCT PCT 1995年9月23日PCT公布。第WO96 / 13734号公报日期：1996年5月9日本发明涉及一种用于X射线的光谱仪，其包括不透辐射的盘，并且具有设置有多个测量最多50μm的通道或孔的第一和第二表面。孔以这样的方式设置，使得它们从第一盘表面延伸到第二盘表面，并且它们的延伸部指向公共线或公共点，公共线或公共点与第二表面相对。还提供了一种借助于这种装置，可以以这样的方式改变盘的拱形，使得公共线或公共点与凹面的距离改变。

4. 发明授权

US5028584A Process and apparatus for producing epitaxial and/or highly textured grown film, free of foreign phases, of a high-T.sub.c -oxide superconductor on a substrate 失效
标题翻译：在衬底上生产高Tc-氧化物超导体的外延和/或高度纹理生长的薄膜（没有异相）的方法和装置
公开(公告)号：US5028584A
公开(公告)日：1991-07-02
申请号：US407989
申请日：1989-09-15
申请人： Christoph Schultheiss , Jochen Geerk , Hans Karow
发明人： Christoph Schultheiss , Jochen Geerk , Hans Karow
IPC分类号： C30B23/08 , C23C14/28 , C23C14/30 , C23C26/02 , C30B23/02 , C30B29/22 , H01B12/06 , H01B13/00 , H01L39/24
CPC分类号： H01L39/2448 , C23C14/28 , C23C14/30 , C23C26/02 , C30B23/02 , C30B29/22 , C30B29/225 , Y10S505/732
摘要： A process for producing an epitaxial and/or highly texturized grown film, free of foreign phases, of a high-T.sub.c -oxide superconductor on a substrate, in which an ablation process is triggered and maintained on a spender target by means of pulsed particles or a laser beams, and the thus developing small droplets are deposited on a heated substrate. The substrate is held at a temperature at which the droplets on impact wet the substrate and coagulate into a uniform smooth film.An apparatus for this process comprises an electron source which produces a pulsed electron beam with an electron energy of about 10 to 20 keV and a current density in the range of 10.sup.3 to 10.sup.4 A/cm.sup.2.
摘要翻译：一种用于在衬底上生产高Tc氧化物超导体的外延和/或高度组织化的外延和/或高度组织化的生长膜的方法，其中消融过程通过脉冲粒子触发并保持在花束靶上，激光束，并且由此显影的小液滴沉积在加热的基底上。将基板保持在冲击下的液滴湿润基板并凝固成均匀光滑膜的温度。用于该方法的装置包括电子源，其产生具有约10至20keV的电子能量和103至104A / cm 2范围内的电流密度的脉冲电子束。

5. 发明授权

US06761858B2 Method and apparatus for processing ashes of incinerator plants 失效
标题翻译：焚烧炉植物灰烬处理方法及装置
公开(公告)号：US06761858B2
公开(公告)日：2004-07-13
申请号：US09906941
申请日：2001-07-18
申请人： Christoph Schultheiss , Christel Adelheim , Britta Bergfeldt , Ralf Straessner , Volker Neubert , Helmul Denning , Bernard Kotte
发明人： Christoph Schultheiss , Christel Adelheim , Britta Bergfeldt , Ralf Straessner , Volker Neubert , Helmul Denning , Bernard Kotte
IPC分类号： B01J1908
CPC分类号： C22B7/005 , B02C19/18 , B02C2019/183 , B03B9/04 , B09B3/00 , C22B7/006 , C22B7/04 , Y02P10/234
摘要： In a method and apparatus for processing materials comprising ashes from waste incineration plants and mineral residues to condition them in a short time by washing them and by subjecting them to electrodynamic processes and shock waves generated by high voltage spark discharges, the material is made chemically inert and aged so that it can be used immediately after treatment without harming the environment.
摘要翻译：在用于处理来自废物焚烧厂和矿物残余物的灰分的材料的处理材料的方法和装置中，通过洗涤它们并在短时间内对其进行电动处理和由高压火花放电产生的冲击波进行处理，材料被制成化学惰性老化，可以在治疗后立即使用，不会对环境造成伤害。

6. 发明授权

US6049162A Pulsed electron beam source and its use 失效
标题翻译：脉冲电子束源及其应用
公开(公告)号：US6049162A
公开(公告)日：2000-04-11
申请号：US70028
申请日：1998-04-30
申请人： Christoph Schultheiss , Vladimir Engelko , Gerd Kraft , Gustav Schumacher , Georg Muller
发明人： Christoph Schultheiss , Vladimir Engelko , Gerd Kraft , Gustav Schumacher , Georg Muller
IPC分类号： H01J3/02 , H01J37/06 , H01J17/26 , H01J61/28
CPC分类号： H01J3/02 , H01J37/06 , H01J2237/06375 , H01J2237/316
摘要： In a pulsed electron beam source based on the vacuum principle, comprising a vacuum diode having a multi-point emission cathode with a flange and a plurality of emission points, a control grid, a pulse generator, a magnetic compression unit consisting of field coils, a drift chamber, a target chamber and a synchronization unit, the multipoint emission cathode is embedded in a shield electrode, and the shield electrode is connected to the cathode base by way of a resistor which is so sized that the shield electrode is capable of freely floating.
摘要翻译：在基于真空原理的脉冲电子束源中，包括具有法兰和多个发射点的多点发射阴极的真空二极管，控制栅格，脉冲发生器，由场线圈组成的磁压缩单元，漂移室，目标室和同步单元，多点发射阴极嵌入屏蔽电极中，屏蔽电极通过电阻器连接到阴极基座，电阻器的尺寸使得屏蔽电极能够自由地浮动

7. 发明授权

US07691324B2 Method and reactor for the non-thermal decomposition and pasteurization of organic process materials by electroporation 失效
标题翻译：通过电穿孔对有机工艺材料进行非热分解和巴氏灭菌的方法和反应器
公开(公告)号：US07691324B2
公开(公告)日：2010-04-06
申请号：US10783875
申请日：2004-02-20
申请人： Christoph Schultheiss
发明人： Christoph Schultheiss
IPC分类号： B08B17/00 , A61L2/00 , B01J19/08 , C12N13/00 , C12M1/00 , C25D5/14 , C25D11/20 , B01D17/06 , A23C3/07 , A21D6/00
CPC分类号： C02F1/4608 , A23L3/32 , A23L5/30 , A23L13/76 , C02F2103/32 , C13B10/08 , Y10S422/905 , Y10S422/907
摘要： In a reaction chamber, which constitutes a component of a process installation for obtaining foodstuffs or foodstuff components, biological products in harvested form that are whole or in pieces are subjected to pulsed electric fields as they pass through said reaction chamber, said electric fields forming pores in the cell walls so as to irreversibly open the latter, thus making the content of the cells more easily accessible. This is achieved by electrode groups, which can be energized to a high voltage and are located in the wall of a longitudinal passage of the reactor through which the process material is moved past grounded electrodes located in an opposing longitudinal wall area. Each electrode group is connected to an electric energy accumulator such as for example, a Marx generator, by means of a switch, in order to rapidly establish electric fields of multiple directions between the charged and the grounded electrodes.
摘要翻译：在构成用于获取食品或食品成分的处理装置的部件的反应室中，收获形式的整体或片状的生物产品在通过所述反应室时经受脉冲电场，所述电场形成孔在细胞壁中不可逆地打开后者，从而使细胞的内容更容易接近。这是通过电极组实现的，其可以被激励到高电压并且位于反应器的纵向通道的壁中，通过该组件，处理材料通过其移动通过位于相对的纵向壁区域中的接地电极。每个电极组通过开关连接到诸如马克思发生器的电能蓄能器，以便在充电和接地电极之间快速建立多个方向的电场。

8. 发明申请

US20050199134A1 Electroporation reactor for continuously processing products in the form of pieces 审中-公开
标题翻译：用于连续加工制品形式的电穿孔反应堆
公开(公告)号：US20050199134A1
公开(公告)日：2005-09-15
申请号：US10773051
申请日：2004-02-05
申请人： Christoph Schultheiss , Martin Kern
发明人： Christoph Schultheiss , Martin Kern
IPC分类号： A23C3/07 , A23N1/00
CPC分类号： A23N1/006 , A23C3/07 , C12M35/02
摘要： In an electroporation reactor for continuously processing products in the form of pieces wherein a drum with carrier elements is rotatably supported in a housing of dielectric material in a process liquid through which the products are moved from an inlet to an outlet through a degasification zone, a reaction zone and a discharge zone at the bottom of the housing, a group of electrodes is arranged adjacent the treatment zone and a high voltage is supplied to the electrodes within not more than 3 μsec generating between the electrodes and the grounded drum a large potential difference for the electroporation of all the walls of the process pieces while passing through the reaction zone.
摘要翻译：在用于连续加工成片形式的产品的电穿孔反应器中，其中具有载体元件的滚筒可旋转地支撑在介质材料的壳体中的处理液体中，产物通过其从入口通过脱气区移动到出口，反应区和位于壳体底部的放电区，一组电极被布置在处理区附近，并且在电极和接地鼓之间产生的不超过3个音圈内向电极提供高电压，具有大的电位差用于在通过反应区的过程中所有壁的电穿孔。

9. 发明授权

US5841235A Source for the generation of large area pulsed ion and electron beams 失效
标题翻译：用于生成大面积脉冲离子和电子束的源
公开(公告)号：US5841235A
公开(公告)日：1998-11-24
申请号：US866551
申请日：1997-05-30
申请人： Vladimir Engelko , Harald Giese , Georg Muller , Sven Schalk , Christoph Schultheiss , Hermann Wurz
发明人： Vladimir Engelko , Harald Giese , Georg Muller , Sven Schalk , Christoph Schultheiss , Hermann Wurz
IPC分类号： H01J3/02 , H01J27/08 , H01J37/077 , H01J37/08 , H01J37/00
CPC分类号： H01J37/08 , H01J27/08 , H01J3/025 , H01J37/077
摘要： In a source for the generation of large-area pulsed ion or electron beams from an anode discharge electrode which has openings receiving discharge electrodes forming a vacuum arc plasma source, the discharge is safely triggered by a load which determines the total current and which consists of a parallel circuit including an ohmic resistor and a capacitor wherein the load output is adapted to the internal resistance of the pulse voltage generator. With a dimensioning of the electrical components taking into consideration given limits, a homogeneous beam of charged particles is obtained wherein the particle composition can be all the same or a homogeneous mixture of different particles depending on the choice of electrode materials.
摘要翻译：在用于从具有接收形成真空电弧等离子体源的放电电极的开口的阳极放电电极产生大面积脉冲离子或电子束的源中，该放电由确定总电流的负载安全地触发，并且由负载包括欧姆电阻和电容器的并联电路，其中负载输出适合于脉冲电压发生器的内部电阻。考虑到给定极限的电气元件的尺寸，得到均匀的带电粒子束，其中根据电极材料的选择，颗粒组成可以是全部相同的或不同颗粒的均匀混合物。

10. 发明授权

US5576593A Apparatus for accelerating electrically charged particles 失效
标题翻译：用于加速带电粒子的装置
公开(公告)号：US5576593A
公开(公告)日：1996-11-19
申请号：US301078
申请日：1994-09-06
申请人： Christoph Schultheiss , Martin Konijnenberg , Markus Schwall
发明人： Christoph Schultheiss , Martin Konijnenberg , Markus Schwall
IPC分类号： H01J37/077 , H05H1/06 , H05H1/24 , H05H1/54 , H05H5/00 , H05H9/00
CPC分类号： H05H1/06 , H05H5/00
摘要： In an apparatus for accelerating electrically charged particles from a pulsed plasma reservoir of high particle density in a dielectric tubular chamber which extends from the reservoir and is surrounded by at least two electrodes of which one is disposed at the wall of the reservoir, the dielectric tubular chamber is partially evacuated to a sufficiently low pressure p such that the product of the gas pressure p and the inner diameter d of the tubular chamber is low enough to avoid parasitic discharges in the residual gas charge, and a voltage is applied to the electrodes such that the particles are drawn into the dielectric tubular chamber with high flow density and are accelerated therein thereby forming a charged particle beam whereby the residual gas charge in the dielectric tubular chamber is ionized along the inside wall of the tubular chamber and polarized such that the wall of the dielectric tubular chamber becomes repulsive for the charged particle beam and its axis becomes attractive whereby the charged particle beam is electrostatically focussed and exits the dielectric tubular chamber with log losses.
摘要翻译：在用于从介质管状室中的高颗粒密度的脉冲等离子体储存器加速带电粒子的设备中，该介质管状室从储存器延伸并且被至少两个电极围绕，其中电极设置在储存器的壁处，介电管室被部分抽空到足够低的压力p，使得管状室的气体压力p和内径d的乘积足够低以避免残留气体充电中的寄生放电，并且向电极施加电压颗粒被吸入到具有高流动密度的介质管状室中并在其中被加速，由此形成带电粒子束，由此电介质管腔室中的残余气体电荷沿着管状室的内壁离子化并且被极化，使得壁介质管状室对于带电粒子束变得排斥，其轴线变为由此带电粒子束被静电聚焦并离开具有对数损失的介质管状室。

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