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1. 发明授权

US08105513B2 Pipette tip containing particle-filled polymer monolith 有权
标题翻译：移液管尖端含有颗粒填充聚合物整料
公开(公告)号：US08105513B2
公开(公告)日：2012-01-31
申请号：US12479676
申请日：2009-06-05
申请人： Alexander Bonn , Guenther Bonn , Christian Huck , Bernhard Maerk , Harald Sonderegger , Mathias Rainer , Douglas T. Gjerde
发明人： Alexander Bonn , Guenther Bonn , Christian Huck , Bernhard Maerk , Harald Sonderegger , Mathias Rainer , Douglas T. Gjerde
IPC分类号： B05D7/22 , B01L3/02 , B01D35/02
CPC分类号： B01J20/28042 , B01J20/02 , B01J20/0211 , B01J20/0237 , B01J20/0281 , B01J20/043 , B01J20/048 , B01J20/06 , B01J20/08 , B01J20/103 , B01J20/20 , B01J20/205 , B01J20/26 , B01J20/28007 , B01J20/28026 , B01J2220/64 , B82Y30/00 , G01N2035/1053
摘要： The present invention relates to a pipette tip which is fitted with a porous organic monolith which is doped with active particles. Due to a unique polymerization method, the extraction tips stay highly permeable which allows sample to pass through the monolithic bed. The extraction tip represents an ideal tool for solid phase extraction, especially for desalting, isolating and purifying biomolecules such as peptides and proteins.
摘要翻译：吸液头技术领域本发明涉及一种移液管吸头，其配有掺有活性颗粒的多孔有机整料。由于独特的聚合方法，萃取尖端保持高渗透性，允许样品通过整体床。提取尖端代表固相萃取的理想工具，特别是用于脱盐，分离和纯化生物分子如肽和蛋白质。

2. 发明申请

US20080044451A1 Biological Surfaces 有权
标题翻译：生物表面
公开(公告)号：US20080044451A1
公开(公告)日：2008-02-21
申请号：US11792613
申请日：2005-12-07
申请人： Doris Steinmuller-Nethl , Detlef Steinmuller , Frank Kloss , Robert Gassner , Gunther Bonn , Christian Huck , Muhammed Najam-Ul-Haq , Matthias Rainer , Gunther Stecher
发明人： Doris Steinmuller-Nethl , Detlef Steinmuller , Frank Kloss , Robert Gassner , Gunther Bonn , Christian Huck , Muhammed Najam-Ul-Haq , Matthias Rainer , Gunther Stecher
IPC分类号： A61F2/00 , C12N1/00
CPC分类号： A61L27/303 , A61L27/54 , A61L29/103 , A61L29/16 , A61L31/084
摘要： A base body contains a substrate that is at least partially coated with a carbon-containing layer. The carbon-containing layer is at least partially functionalized with a molecule that is bound directly or via at least one linker or functional group to the carbon-containing layer. The base body, which has a functionalized carbon-containing surface, is capable of influencing biological processes during a corresponding functionalization.
摘要翻译：基体包含至少部分地涂覆有含碳层的基材。含碳层至少部分地被直接结合或通过至少一个与含碳层的接头或官能团结合的分子官能化。具有官能化含碳表面的基体能够在相应的官能化过程中影响生物过程。

3. 发明授权

US07244902B2 Method for classifying wine and coffee 有权
标题翻译：葡萄酒和咖啡分类方法
公开(公告)号：US07244902B2
公开(公告)日：2007-07-17
申请号：US10479064
申请日：2002-05-06
申请人： Michael A. Popp , Günther Bonn , Christian Huck , Wolfgang Guggenbichler
发明人： Michael A. Popp , Günther Bonn , Christian Huck , Wolfgang Guggenbichler
IPC分类号： B07C5/00
CPC分类号： G01N33/146 , G01N33/14 , G06K9/00 , Y10S250/91
摘要： A method for classifying beverages of natural origin, such as wine or coffee. Classification is carried out by means of NIR spectroscopy and corresponding numerical-mathematical conditioning of the spectral data of the individual beverage samples, wherein respective obtained spectra are then correlated with a predetermined beverage, class. By means of the method of the invention it is possible to classify wines by sort of wine, growing regions, grape, vine, vintage, kind of material or wood of the wine cask used, and varying degree of maturity of the wine, and by other chemical parameters. Coffee, for example, may be classified by coffee sort, country of origin, coffee growing region, roasting method and defined chemical parameters, e.g., caffeine content, or chlorogenic acid content.
摘要翻译：用于分类天然来源的饮料的方法，例如葡萄酒或咖啡。通过NIR光谱法和各个饮料样品的光谱数据的相应的数学 - 数学调节进行分类，其中相应的获得的光谱然后与预定饮料类相关。通过本发明的方法，可以通过葡萄酒，生长区域，葡萄，葡萄藤，葡萄酒，葡萄酒，所使用的酒桶的材料或木材，葡萄酒的成熟程度以及葡萄酒的成熟程度来分类葡萄酒。其他化学参数。例如，咖啡可以通过咖啡分类，原产地，咖啡生长区域，焙烧方法和确定的化学参数（例如咖啡因含量或绿原酸含量）进行分类。

4. 发明申请

US20080054171A1 Target for Laser Desorption/Ionisation Mass Spectrometry 审中-公开
标题翻译：激光解吸/电离质谱的目标
公开(公告)号：US20080054171A1
公开(公告)日：2008-03-06
申请号：US11547411
申请日：2004-04-04
申请人： Gunther Bonn , Isabel Feuerstein , Christian Huck , Muhammad Najam-Al-Haq , Matthias Rainer , Gunther Stecher , Georg Schwarzmann , Doris Steinmuller-Nethl , Detlef Steinmuller
发明人： Gunther Bonn , Isabel Feuerstein , Christian Huck , Muhammad Najam-Al-Haq , Matthias Rainer , Gunther Stecher , Georg Schwarzmann , Doris Steinmuller-Nethl , Detlef Steinmuller
IPC分类号： G21K5/04
CPC分类号： H01J49/0418 , B82Y10/00
摘要： The invention relates to a target for a laser desorption/ionisation mass spectrometer, comprising a substrate that is at least partially coated with a carbon-containing layer comprising a material selected from the group consisting of diamond, amorphous carbon, DLC (diamond-like carbon), graphite, nanotubes, nanowires, fullerenes and mixtures thereof.
摘要翻译：本发明涉及一种用于激光解吸/电离质谱仪的靶，其包括至少部分地涂覆有含碳层的基底，所述含碳层包含选自金刚石，无定形碳，DLC（类金刚石碳），石墨，纳米管，纳米线，富勒烯及其混合物。

5. 发明申请

US20100009845A1 Pipette Tip Containing Particle-Filled Polymer Monolith 有权
标题翻译：移液管尖端包含颗粒填充的聚合物整体
公开(公告)号：US20100009845A1
公开(公告)日：2010-01-14
申请号：US12479676
申请日：2009-06-05
申请人： Alexander Bonn , Guenther Bonn , Christian Huck , Bernhard Maerk , Harald Sonderegger , Mathias Rainer , Douglas T. Gjerde
发明人： Alexander Bonn , Guenther Bonn , Christian Huck , Bernhard Maerk , Harald Sonderegger , Mathias Rainer , Douglas T. Gjerde
IPC分类号： B01J20/26
CPC分类号： B01J20/28042 , B01J20/02 , B01J20/0211 , B01J20/0237 , B01J20/0281 , B01J20/043 , B01J20/048 , B01J20/06 , B01J20/08 , B01J20/103 , B01J20/20 , B01J20/205 , B01J20/26 , B01J20/28007 , B01J20/28026 , B01J2220/64 , B82Y30/00 , G01N2035/1053
摘要： The present invention relates to a pipette tip which is fitted with a porous organic monolith which is doped with active particles. Due to a unique polymerization method, the extraction tips stay highly permeable which allows sample to pass through the monolithic bed. The extraction tip represents an ideal tool for solid phase extraction, especially for desalting, isolating and purifying biomolecules such as peptides and proteins.
摘要翻译：吸液头技术领域本发明涉及一种移液管吸头，其配有掺有活性颗粒的多孔有机整料。由于独特的聚合方法，萃取尖端保持高渗透性，允许样品通过整体床。提取尖端代表固相萃取的理想工具，特别是用于脱盐，分离和纯化生物分子如肽和蛋白质。

6. 发明授权

US08053247B2 Method and device for preparing an analyte for analysis by mass spectrometry 有权
标题翻译：用于通过质谱法制备用于分析的分析物的方法和装置
公开(公告)号：US08053247B2
公开(公告)日：2011-11-08
申请号：US11973912
申请日：2007-10-10
申请人： Isabel Feuerstein , Günther Bonn , Douglas T. Gjerde , Christian Huck , Guenther Stecher
发明人： Isabel Feuerstein , Günther Bonn , Douglas T. Gjerde , Christian Huck , Guenther Stecher
IPC分类号： G01N1/00 , G01N1/18
CPC分类号： G01N35/028 , G01N1/34 , G01N2035/103 , Y10T436/11 , Y10T436/119163 , Y10T436/25 , Y10T436/255 , Y10T436/2575
摘要： The invention provides methods and apparatus for automated sample preparation for MALDI-TOF MS using columns in combination with a liquid handling system. The samples are typically biological such as serum or urine. The columns typically include a bed of media positioned within a modified pipette tip. In some embodiments, the invention provides methods for storing the prepared samples.
摘要翻译：本发明提供用于使用与液体处理系统结合的柱的MALDI-TOF MS的自动化样品制备的方法和装置。样品通常是生物的，如血清或尿液。柱通常包括定位在改进的移液管尖端内的介质床。在一些实施方案中，本发明提供了储存所制备样品的方法。

7. 发明申请

US20080090295A1 Method and device for preparing an analyte for analysis by mass spectrometry 有权
标题翻译：用于通过质谱法制备用于分析的分析物的方法和装置
公开(公告)号：US20080090295A1
公开(公告)日：2008-04-17
申请号：US11973912
申请日：2007-10-10
申请人： Isabel Feuerstein , Gunther Bonn , Douglas Gjerde , Christian Huck , Guenther Stecher
发明人： Isabel Feuerstein , Gunther Bonn , Douglas Gjerde , Christian Huck , Guenther Stecher
IPC分类号： G01N35/10 , G01N35/00
CPC分类号： G01N35/028 , G01N1/34 , G01N2035/103 , Y10T436/11 , Y10T436/119163 , Y10T436/25 , Y10T436/255 , Y10T436/2575
摘要： The invention provides methods and apparatus for automated sample preparation for MALDI-TOF MS using columns in combination with a liquid handling system. The samples are typically biological such as serum or urine. The columns typically include a bed of media positioned within a modified pipette tip. In some embodiments, the invention provides methods for storing the prepared samples.
摘要翻译：本发明提供用于使用与液体处理系统结合的柱的MALDI-TOF MS的自动化样品制备的方法和装置。样品通常是生物的，如血清或尿液。柱通常包括定位在改进的移液管尖端内的介质床。在一些实施方案中，本发明提供了储存所制备样品的方法。

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