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1. 发明申请

US20120129193A1 DEVICE AND METHOD FOR ANALYSING CELLS 审中-公开
标题翻译：用于分析细胞的装置和方法
公开(公告)号：US20120129193A1
公开(公告)日：2012-05-24
申请号：US13126116
申请日：2009-10-27
申请人： Christian Hennig , Gesine Hansen
发明人： Christian Hennig , Gesine Hansen
IPC分类号： G01N21/64 , C12M1/34
CPC分类号： G01N33/5005 , B01L3/5027
摘要： There is provided a carrier substrate for nonspecific immobilization of living bacterial and/or eukaryotic cells, especially of animal cells, which can be present as single cells, cell agglomerates or tissue sections. The surface of the carrier substrate is provided at least sectionally with a layer having or consisting of oligonucleic acids, preferably having ribonucleic acids covalently coupled to the carrier substrate, e.g. RNA, preferably single-stranded or double-stranded DNA.
摘要翻译：提供了用于非特异性固定生物细菌和/或真核细胞，特别是动物细胞的载体底物，其可以作为单细胞，细胞聚集体或组织切片存在。载体衬底的表面至少部分地设置有具有或由低聚核酸组成的层，优选具有共价偶联到载体衬底的核糖核酸，例如， RNA，优选单链或双链DNA。

2. 发明申请

US20100096727A1 SEMI-CONDUCTOR SUBSTRATE AND METHOD OF MASKING LAYER FOR PRODUCING A FREE-STANDING SEMI-CONDUCTOR SUBSTRATE BY MEANS OF HYDRIDE-GAS PHASE EPITAXY 有权
标题翻译：半导体基板和用于通过氢化气相外延生产自由稳定的半导体基板的掩膜层的方法
公开(公告)号：US20100096727A1
公开(公告)日：2010-04-22
申请号：US11996446
申请日：2006-08-24
申请人： Christian Hennig , Markus Weyers , Eberhard Richter , Guenther Traenkle
发明人： Christian Hennig , Markus Weyers , Eberhard Richter , Guenther Traenkle
IPC分类号： H01L29/12 , H01L21/205 , C30B25/04 , H01L21/78
CPC分类号： H01L21/0262 , H01L21/0237 , H01L21/02378 , H01L21/0242 , H01L21/02458 , H01L21/02502 , H01L21/0254 , H01L21/02581 , H01L21/02642 , H01L21/02647
摘要： The invention relates to a free-standing semiconductor substrate as well as a process and a mask layer for the manufacture of a free-standing semiconductor substrate, wherein the semiconductor substrate self-separates from the starting substrate without further process steps.The process according to the invention for the manufacture of a semiconductor substrate comprises the following process steps: providing a starting substrate, forming a mask layer with a multitude of openings on the starting substrate, growing at least one semiconductor substrate, wherein the mask layer is laterally overgrown by at least one semiconductor material, and subsequent, cooling of starting substrate, mask layer and semiconductor substrate, wherein the material for forming the mask layer consists at least partially of tungsten silicide nitride or tungsten silicide, and wherein the semiconductor substrate and the starting substrate are caused to separate during the growth of the at least one semiconductor substrate or during cooling, and wherein a semiconductor substrate is obtained free-standing. The mask layer according to the invention for the manufacture of a free-standing semiconductor substrate here consists at least partially of tungsten silicide nitride or tungsten silicide.
摘要翻译：本发明涉及独立式半导体衬底以及用于制造独立式半导体衬底的工艺和掩模层，其中半导体衬底与起始衬底自分离而无需进一步的工艺步骤。根据本发明的用于制造半导体衬底的方法包括以下工艺步骤：提供起始衬底，在起始衬底上形成具有多个开口的掩模层，生长至少一个半导体衬底，其中掩模层是由至少一种半导体材料横向长满，以及随后冷却起始衬底，掩模层和半导体衬底，其中用于形成掩模层的材料至少部分由硅化钨或硅化钨组成，并且其中半导体衬底和使起始衬底在至少一个半导体衬底的生长期间或在冷却期间分离，并且其中独立地获得半导体衬底。本发明的用于制造独立式半导体衬底的掩模层至少部分地由硅化钨或氮化硅构成。

3. 发明授权

US08865414B2 Detection conjugate and method for analysis 有权
标题翻译：检测共轭和分析方法
公开(公告)号：US08865414B2
公开(公告)日：2014-10-21
申请号：US13139870
申请日：2009-12-17
申请人： Christian Hennig , Gesine Hansen
发明人： Christian Hennig , Gesine Hansen
IPC分类号： G01N33/53 , C07K14/00 , C07K16/00 , C12Q1/68 , C07H21/00 , C07H21/02 , C07H21/04
CPC分类号： C12Q1/6804 , C12Q2565/101
摘要： The invention provides a combination of reagents as a test kit containing a detection conjugate having a binding portion and a reagent for deactivating of the fluorochrome portion by interaction with the linker. The binding portion especially is an antibody portion. The detection conjugate has a fluorochrome portion connected to the antibody portion, and a linker connected to the fluorochrome portion, wherein the linker comprises an oligonucleotide. The fluorochrome portion can be deactivated by hydrolysis of the linker or by specific hybridization of a quencher having an oligonucleotide to the linker.
摘要翻译：本发明提供试剂的组合作为测试试剂盒，其含有具有结合部分的检测缀合物和通过与接头相互作用而使荧光染料部分失活的试剂。结合部分特别是抗体部分。检测缀合物具有连接到抗体部分的荧光染料部分和与荧光染料部分连接的连接体，其中连接体包含寡核苷酸。可以通过接头的水解或通过具有寡核苷酸的猝灭剂与接头的特异性杂交来使荧光染料部分失活。

4. 发明授权

US08637650B2 Macromolecular nucleotide compounds and methods for using the same 有权
标题翻译：大分子核苷酸化合物及其使用方法
公开(公告)号：US08637650B2
公开(公告)日：2014-01-28
申请号：US10578313
申请日：2004-11-05
申请人： Dmitry Cherkasov , Christian Hennig
发明人： Dmitry Cherkasov , Christian Hennig
IPC分类号： C07H21/02 , C07H21/04 , C07H21/00 , C07H19/04 , C12Q1/68 , C12P19/34
CPC分类号： C07H21/00 , C07H19/06 , C07H19/10 , C07H19/16 , C07H19/20 , C12Q1/6848 , C12Q1/6869 , C12Q2525/113 , C12Q2525/197
摘要： The invention relates to novel classes of nucleotides that can be used as substrates for enzymes, e.g. for labeling nucleic acids.
摘要翻译：本发明涉及可用作酶底物的新型核苷酸，例如，用于标记核酸。

5. 发明授权

US08591652B2 Semi-conductor substrate and method of masking layer for producing a free-standing semi-conductor substrate by means of hydride-gas phase epitaxy 有权
标题翻译：半导体基板和通过氢化物 - 气相外延生产独立的半导体基板的掩模层的方法
公开(公告)号：US08591652B2
公开(公告)日：2013-11-26
申请号：US11996446
申请日：2006-08-24
申请人： Christian Hennig , Markus Weyers , Eberhard Richter , Guenther Traenkle
发明人： Christian Hennig , Markus Weyers , Eberhard Richter , Guenther Traenkle
IPC分类号： C30B25/04
CPC分类号： H01L21/0262 , H01L21/0237 , H01L21/02378 , H01L21/0242 , H01L21/02458 , H01L21/02502 , H01L21/0254 , H01L21/02581 , H01L21/02642 , H01L21/02647
摘要： The invention relates to a free-standing semiconductor substrate as well as a process and a mask layer for the manufacture of a free-standing semiconductor substrate, wherein the material for forming the mask layer consists at least partially of tungsten silicide nitride or tungsten silicide and wherein the semiconductor substrate self-separates from the starting substrate without further process steps.
摘要翻译：本发明涉及独立式半导体衬底以及用于制造独立式半导体衬底的工艺和掩模层，其中用于形成掩模层的材料至少部分由硅化钨或硅化钨组成，其中所述半导体衬底在没有进一步的工艺步骤的情况下与所述起始衬底自分离。

6. 发明申请

US20110311966A1 DETECTION CONJUGATE AND METHOD FOR ANALYSIS 有权
标题翻译：检测结合和分析方法
公开(公告)号：US20110311966A1
公开(公告)日：2011-12-22
申请号：US13139870
申请日：2009-12-17
申请人： Christian Hennig , Gesine Hansen
发明人： Christian Hennig , Gesine Hansen
IPC分类号： G01N21/64 , C12Q1/68
CPC分类号： C12Q1/6804 , C12Q2565/101
摘要： The invention provides a combination of reagents as a test kit containing a detection conjugate having a binding portion and a reagent for deactivating of the fluorochrome portion by interaction with the linker. The binding portion especially is an antibody portion. The detection conjugate has a fluorochrome portion connected to the antibody portion, and a linker connected to the fluorochrome portion, wherein the linker comprises an oligonucleotide. The fluorochrome portion can be deactivated by hydrolysis of the linker or by specific hybridization of a quencher having an oligonucleotide to the linker.
摘要翻译：本发明提供试剂的组合作为测试试剂盒，其含有具有结合部分的检测缀合物和通过与接头相互作用而使荧光染料部分失活的试剂。结合部分特别是抗体部分。检测缀合物具有连接到抗体部分的荧光染料部分和与荧光染料部分连接的连接体，其中连接体包含寡核苷酸。可以通过接头的水解或通过具有寡核苷酸的猝灭剂与接头的特异性杂交来使荧光染料部分失活。

7. 发明申请

US20100029494A1 Macromolecular Nucleotide Compounds And Methods For Using The Same 有权
标题翻译：大分子核苷酸化合物及其使用方法
公开(公告)号：US20100029494A1
公开(公告)日：2010-02-04
申请号：US10578313
申请日：2004-11-05
申请人： Dmitry Cherkasov , Christian Hennig
发明人： Dmitry Cherkasov , Christian Hennig
IPC分类号： C40B30/04 , C07H21/00 , C07H21/02 , C07H21/04 , C07K14/00 , C12P19/34 , C40B50/14 , C12Q1/68 , C08F283/00 , C07K16/00 , C12N9/96 , C07K9/00
CPC分类号： C07H21/00 , C07H19/06 , C07H19/10 , C07H19/16 , C07H19/20 , C12Q1/6848 , C12Q1/6869 , C12Q2525/113 , C12Q2525/197
摘要： The invention relates to novel classes of nucleotides that can be used as substrates for enzymes, e.g. for labeling nucleic acids.
摘要翻译：本发明涉及可用作酶底物的新型核苷酸，例如，用于标记核酸。

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